Navigation Links
Old stain in a new combination
Date:5/20/2009

etocytes and thus improve the control of malaria," states Professor Dr. Olaf Mller, Project Head in the Department of Tropical Medicine and Public Health of the Hygiene Institute at the University of Heidelberg.

Methylene blue prevents transmission to mosquitoes

The appropriate component for such an alternative is a proven agent the methylene blue stain which has been given to malaria patients since the end of the 19th century has proven to be safe, well tolerated, and effective in combination with various malaria medications.

In the current study in Burkina Faso with 160 malaria patients between the ages of six and ten the Heidelberg scientists tested the effect of combination therapies with artemisinins and methylene blue on gametocytes in the blood. One group of the children received the standard treatment, consisting of a combination of artesunate and amodiaquine. Two other groups received methylene blue combined with one of the two drugs respectively. The physicians checked the number of gametocytes in blood samples three, seven, and fourteen days after the start of therapy.

Combination therapy is twice as effective as standard therapy

It was shown that both combination therapies are twice as effective against gametocytes as the standard therapy these parasites had almost completely disappeared in the first few days. "Methylene blue not only inhibits the formation of the reproductive forms, but also destroys already existing cells," explains Professor Mller. "In this way, the profiles of methylene blue and artemisinins, which quickly and effectively eliminate the parasites in the red blood cells, complement each other." Since the study group from Heidelberg has used methylene blue in Western Africa for years, it has already been adequately clinically tested severe or frequent side effects did not occur. Especially important is that the combination makes it more difficult for resistance to artemisi
'/>"/>

Contact: Prof. Olaf Mueller
Olaf.mueller@urz.uni-heidelberg.de
49-062-215-65035
University Hospital Heidelberg
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Grasslands: The future of sustainable agriculture
2. Going bananas for sustainable research -- scientists create fuel from African crop waste
3. K-State biologist collaborating with researchers in Africa on grassland sustainability, biodiversity
4. Organizational Change Management for Sustainability: The Harvard Case Study
5. Biofuels can provide viable, sustainable solution to reducing petroleum dependence
6. Symposium at UH will address how to put sustainability into practice
7. Biggest ever public investment in bioenergy to help provide clean, green and sustainable fuels
8. TXOTX, coordinated international project to contribute to sustainability of the marine resources
9. Abundance of ladybugs in olive orchards is an indicator of health and sustainability
10. Next generation microscopy: No stain, big gain
11. New publishing partnership for Energy for Sustainable Development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/8/2015)... May 8, 2015 Synaptics Inc. (NASDAQ: SYNA ... that members of the executive management team will present at ... Technology, Media and Telecom Conference Date: May 18, 2015 ... Boston, MA Cowen and Company ... 2:45pm ET Location: The New York Palace Hotel, ...
(Date:4/27/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... growing mobile commerce market, announces that its Wocket® Smart ... week of May, 2015 and will be fulfilling all ... Gino Pereira , Chief Executive Officer said, ... Wocket® enters the consumer market. We would like to ...
(Date:4/17/2015)... 2015 Increasing adoption ... advancement to drive biometric systems market in ... According to a recently released TechSci ... ", biometric systems market in Saudi ... at CAGR of over 22% through 2020. The ...
Breaking Biology News(10 mins):Synaptics to Present at Upcoming Investor Conferences 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 2Wocket, the Smartest Wallet You Will Ever Own, Announces Shipment to Pre-order Customers 3Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3
... team of researchers from the United States, Korea, and France ... strains of E. coli bacteria, one used to ... research or practical applications. The findings will help guide future ... understanding of classical research that is the foundation of our ...
... research is suggesting new ways to aid recovery after ... recovery rate and show how to make stem cell ... presented at Neuroscience 2009, the annual meeting of the ... emerging news on brain science and health. In ...
... of tons of fruits and vegetables in the United States ... to the U.S. Department of Agriculture? A Georgia State ... produce and flowers fresh for longer periods of time. ,Microbiologist ... larger than the width of a human hair to ...
Cached Biology News:Genomes of 2 popular research strains of E. coli sequenced 2Genomes of 2 popular research strains of E. coli sequenced 3Researchers find ways to encourage spinal cord regeneration after injury 2GSU professor develops new method to help keep fruit, vegetables and flowers fresh 2
(Date:5/27/2015)... MA (PRWEB) May 27, 2015 The ... is directing, via its wholly owned subsidiary, Anelixis ... potential treatment for ALS that targets the innate immune ... ALS Therapy Development Institute received from the 2014 social ... The entire sum of $4 million raised directly by ...
(Date:5/27/2015)... Calif. , May 27, 2015  Two years ... biotech professionals, hackers and citizen scientists, Oakland ... $30,000 crowdfunding campaign promoting its mission to democratize science ... Temescal District. ... Based out of ...
(Date:5/27/2015)... Madison, NJ (PRWEB) May 27, 2015 ... for evaluating the impact of regulation on medical innovation, ... Centered Innovation (iPCI) of Fairleigh Dickinson University’s ( ... inaugural MI3 Alert pertains to new FDA ... Senate proposal for accelerating the approval of certain medical ...
(Date:5/26/2015)... WORMS, GERMANY – May 26, ... GRA) announces that its manufacturing facility in Worms, ... from EXCiPACT™, an independent organization that certifies manufacturers, ... , All three Grace facilities that produce its ... gels have now received GMP certification, following the ...
Breaking Biology Technology:Ice Bucket Challenge Advances Antibody Toward Clinical Trial for ALS 2Ice Bucket Challenge Advances Antibody Toward Clinical Trial for ALS 3East Bay's Counter Culture Labs Seeks to Open Doors of Science to Public 2East Bay's Counter Culture Labs Seeks to Open Doors of Science to Public 3Medical Innovation Impact Index Launched at Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) under the Rothman Institute 2CORRECTION: Grace European Facility Receives GMP Excipient Certification for SYLOID® FP Silica Gel 2
... Stock Exchange Symbol: MS , , EDMONTON, July 17 ... in the treatment of multiple sclerosis (MS), today announced financial ... June 30, 2009. , "The pivotal phase III MAESTRO-01 trial ... expecting results from this study within the second half of ...
... , MINNETONKA, Minn., July 17 John H. ... - Minneapolis, one of several new Sanford Rose Associates executive ... as Chief Technology Officer at CircuLite, Inc. With a 30-year ... Jude Medical, John is a natural fit to spearhead the ...
... HOPKINTON, Mass., July 16 Caliper Life Sciences, Inc. (Nasdaq: ... second quarter 2009 financial results at 9:00 a.m. ET on Thursday, ... Peter McAree, Chief Financial Officer, will host the call. Management will ... future. , , A news ...
Cached Biology Technology:BioMS Medical announces second quarter 2009 results 2BioMS Medical announces second quarter 2009 results 3BioMS Medical announces second quarter 2009 results 4BioMS Medical announces second quarter 2009 results 5BioMS Medical announces second quarter 2009 results 6BioMS Medical announces second quarter 2009 results 7BioMS Medical announces second quarter 2009 results 8BioMS Medical announces second quarter 2009 results 9Sanford Rose Associates Opens Minneapolis Office 2Caliper Life Sciences' Second Quarter 2009 Financial Results Conference Call Notice 2
... Supplied with two sets of glass plates, ... cooling plate. Special features of these units ... and lower buffer reservoirs , upper and ... for easy and safe disposal of buffer ...
... is a cytochrome P450 (CYP450) metabolite postulated ... renal and cerebral vasculature. In rat cerebral ... pressure-induced autoregulatory vasoconstriction. 20-HETE is excreted mainly ... free 20-HETE (20-40 pg/ml in human urine) ...
... APAgene kits are designed to rapidly and ... our patented APA Technology. APAgene provides hassle-free, ... price. All necessary ingredients are provided in ... be used for gap filling, localized cloning ...
... designed to rapidly and reliably amplify ... patented APA Technology. APAgene provides hassle-free, ... competitive price. All necessary ingredients are ... Kit can be used for identifying ...
Biology Products: