Navigation Links
Old drug may point the way to new treatments for diabetes and obesity
Date:2/10/2013

d obese mice. The chemical lowered the weight of obese mice and reversed related metabolic problems such as diabetes and fatty liver.

"These studies tell us that, at least in mice, the IKKE/TBK1 pathway plays an important role in defending body weight by increasing storage and decreasing burning of calories, and that by inhibiting that pathway with a compound, we can increase metabolism and induce weight loss, reverse diabetes and reduce fatty liver," Saltiel said.

The drug has been on the market in Japan for more than 25 years.

However, the researchers don't yet know if humans respond with the same pathway, or if the discovery of amlexanox's effectiveness in mice can lead to a compound that is safe and effective for treating obesity and diabetes in humans.

"We will be working hard on that," Saltiel said.


'/>"/>

Contact: Laura J. Williams
laurajw@umich.edu
734-615-4862
University of Michigan
Source:Eurekalert

Page: 1 2

Related biology news :

1. Bluemetal Architects appoints David Le Penske as Vice President of Health & Life Sciences
2. Summit of osteoporosis experts from CIS countries issue 5-point call for action
3. Scientists pinpoint molecular signals that make some women prone to miscarriage
4. Serendipity points to new potential target and therapy for melanoma
5. Research pinpoints key gene for regenerating cells after heart attack
6. Fish ear bones point to climate impacts
7. Protein injection points to muscular dystrophy treatment
8. University of Maryland School of Medicine, NIH study pinpoints brain areas role in learning
9. New study to examine ecological tipping points in hopes of preventing them
10. Fossil study helps pinpoint extinction risks for ocean animals
11. Remarkable enzyme points the way to reducing nitric acid use in industry
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/16/2015)... 2015  With the increasing number and severity of ... concern. The recent compromise of Federal employee data ... authentication within government agencies. HYPR Corp. announced ... (OTP) authenticator, has been submitted for testing and approval ... validation for tamper proofing. The proliferation ...
(Date:6/15/2015)... 16, 2015 According to a ... Type (Rule-Based, Statistical, and Hybrid), Technologies (Recognition, IVR, OCR, ... published by MarketsandMarkets, The Natural Language Processing Market is ... of 18.4% for the forecast period 2015-2020. ... F igures spread   through 155 P ...
(Date:6/12/2015)... DALLAS , June 12, 2015  Securus ... justice technology solutions for public safety, investigation, corrections ... issued its patent to electronically capture, analyze and ... various facial recognition methods. This system ... authorized by an enrollment and subsequent sign-on process ...
Breaking Biology News(10 mins):Government Ready Biometric Security Approaching as HYPR Corp. Files FIPS 140-2 Level 3 Validation for Its Proprietary Biometric Token 2Government Ready Biometric Security Approaching as HYPR Corp. Files FIPS 140-2 Level 3 Validation for Its Proprietary Biometric Token 3Natural Language Processing Market Worth $13.4 Billion by 2020 2Natural Language Processing Market Worth $13.4 Billion by 2020 3Natural Language Processing Market Worth $13.4 Billion by 2020 4Natural Language Processing Market Worth $13.4 Billion by 2020 5Securus Announces Patent Issued for Authorized Presence Verification During Video Visitation 2
... WI, August 2nd, 2010 Scientists demonstrate that biochar, ... capture and store carbon, can reduce emissions of nitrous ... from agriculture settings. The finding will help develop strategies ... reduce agriculture,s influence on climate change. A research ...
... Like a scout that runs ahead to spot signs ... yeast cells, genome during replication -- a process vulnerable to ... research. Researchers from Cornell University,s Weill Institute for Cell ... plays the role of "guardian of the genome," explained Marcus ...
... release is available in Spanish . , Scientists ... make up your body. But mysteries remain regarding the exact ... strengthening our skeletons. Those compounds include estrogen-like substances known as ... Van Loan and other researchers learned more about these compounds ...
Cached Biology News:Is biochar the answer for ag? 2'Guardian of the genome': Protein helps prevent damaged DNA in yeast 2Do soy isoflavones boost bone health? 2
(Date:7/6/2015)... BARBARA, Calif. , July 6, 2015  Approximately ... that is integrated into their chromosomes. These individuals are ... a new study published in one of the nation,s ... Faculty of Medicine in Canada.  Photo - ... as human herpesvirus 6 (HHV-6) causes roseola (also known ...
(Date:7/6/2015)... , July 6, 2015 Navitas, a leading Regulatory Service ... America hub in Bogota, Colombia . Navitas, ... the many benefits provided by Colombia , the third ... Logo - http://photos.prnewswire.com/prnh/20150703/228239LOGO ... location, allows US based clients to communicate with Navitas regulatory professionals in ...
(Date:7/3/2015)... ... July 03, 2015 , ... The Alexander Group, a ... service industries alike-- typically known for its consummate professionalism-- embarks each year in ... and break from their day jobs. , "Our motto has always been work ...
(Date:7/3/2015)... , July 3, 2015 ... den 22. september 2015 på  http://www.openinnovationinscience.at ... Science", der finder sted i ... nylig undersøgelse af internationale forskere og videnskabsmænd ... de to største udfordringer for sundhedsvidenskaben manglen ...
Breaking Biology Technology:Inherited Herpes Virus Increases the Risk of Angina Reports HHV-6 Foundation 2Inherited Herpes Virus Increases the Risk of Angina Reports HHV-6 Foundation 3Navitas Launches Latin American Regulatory Operations Hub in Bogota, Colombia 2Navitas Launches Latin American Regulatory Operations Hub in Bogota, Colombia 3The Alexander Group Declares Their Independence with a Bit of Levity 2Lancering af verdens første åbne innovationsprogram til uddannelse af forskere 2Lancering af verdens første åbne innovationsprogram til uddannelse af forskere 3
... and health providers draws dozens of life science companies ... ... The unique connectivity, talent and,collaboration that has attracted many of ... will be on show at BIO 2008 in San,Diego, California ...
... NovaVision today announced,the appointment of Rudy Mazzocchi ... Mazzocchi is responsible for leveraging the company,s novel,technology ... that patients with,impaired vision have access to NovaVision(R) ... of expertise bringing new medical technologies,and devices to ...
... PASADENA, Calif., June 16 Alexandria Real Estate,Equities, ... more than 100 life science,executives from around the ... certified,buildings and environmentally sustainable operations in the San ... Tour is being held in,conjunction with the Biotechnology ...
Cached Biology Technology:Scotland Showcased at BIO as Dynamic, Global Life Sciences Hub 2Scotland Showcased at BIO as Dynamic, Global Life Sciences Hub 3NovaVision Appoints Medical Technology Veteran Rudy Mazzocchi as Chief Executive Officer 2NovaVision Appoints Medical Technology Veteran Rudy Mazzocchi as Chief Executive Officer 3Alexandria Real Estate Equities, Inc. Features Green Buildings and Sustainable Operations Initiatives and Tour at 2008 BIO 2Alexandria Real Estate Equities, Inc. Features Green Buildings and Sustainable Operations Initiatives and Tour at 2008 BIO 3Alexandria Real Estate Equities, Inc. Features Green Buildings and Sustainable Operations Initiatives and Tour at 2008 BIO 4
... (enzyme-lined immunospot) Kit analyzes interferon gamma (IFNγ) ... spot forms at the site where secreted ... a dissection microscope or automated ELISPOT reader) ... cells added to the microplate. This allows ...
... CLS number is a ... to easily match Cornings ... no availability yet, please ... Sigma-Aldrich number (Z71,515-8) or ...
... of your microarray data using Asuragens bioinformatics ... from consultation to extensive data analysis using ... our expertise in combination with the Gene ... microarray experiments., ,Normalization and basic statistical analysis ...
... number is a new product number, ... number. If showing no availability yet, ... number (Z71,517-4) or contact customer service ... (expanded surface, easy grip) ...
Biology Products: