Navigation Links
Nutrient in eggs and meat may influence gene expression from infancy to adulthood
Date:9/20/2012

ntinue to have a long-lasting influence on adult life," said Eva K. Pressman, M.D., study author and director of the high-risk pregnancy program at the University of Rochester Medical Center. "While our results won't change practice at this point, the idea that maternal choline intake could essentially change fetal genetic expression into adulthood is quite novel."

Pressman, who advises pregnant women every day, says choline isn't something people think a lot about because it is already present in many things we eat and there is usually no concern of choline deficiency. Though much more research has focused on folate functionally very similar to choline and used to decrease the risk of neural tube defects like spina bifida a few very compelling studies sparked her interest, including animal studies on the role of choline in mitigating fetal alcohol syndrome and changing outcomes in Down syndrome.

A long-time collaborator with researchers at Cornell, Pressman joined a team led by Marie Caudill, Ph.D., R.D., professor in the Division of Nutritional Sciences at Cornell, in studying 26 pregnant women in their third trimester who were assigned to take 480 mg per day, an amount slightly above the standard recommendation of 450 mg per day, or about double that amount, 930 mg per day. The choline was derived from the diet and from supplements and was consumed up until delivery.

The team found that higher maternal choline intake led to a greater amount of DNA methylation, a process in which methyl groups one carbon atom linked to three hydrogen atoms are added to our DNA. Choline is one of a handful of nutrients that provides methyl groups for this process. The addition of a single methyl group is all it takes to change an individual's epigenome.

Measurements of cord blood and samples from the placenta showed that increased choline, via the addition of methyl groups, altered epigenetic markers that govern cortisol-regulating genes
'/>"/>

Contact: Emily Boynton
emily_boynton@urmc.rochester.edu
585-273-1757
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
2. Consumers need simple, concise messages about benefits of phytonutrients
3. Nutrient and toxin all at once: How plants absorb the perfect quantity of minerals
4. Obtaining key nutrients from canned foods can save consumers money
5. Prenatal micronutrient, food supplementation intervention in Bangladesh decreases child death rate
6. Study: No-fat, low-fat dressings dont get most nutrients out of salads
7. U OF A expert pinpoints nutrient behind fresh water algae blooms
8. Increased sediment and nutrients delivered to bay as Susquehanna reservoirs near sediment capacity
9. Circadian rhythms have profound influence on metabolic output, UCI study reveals
10. BUSM researchers identify genes that influence hippocampal volume
11. Fat outside of arteries may influence onset of coronary artery disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2015)... Calif. , April 20, 2015 Huntington ... Gabriel Valley to implant a new miniaturized, wireless monitoring ... System is the first and only FDA-approved heart failure ... hospital admissions when used by physicians to manage heart ... sensor that is implanted in the pulmonary artery (PA) ...
(Date:4/17/2015)... 2015 Increasing adoption ... advancement to drive biometric systems market in ... According to a recently released TechSci ... ", biometric systems market in Saudi ... at CAGR of over 22% through 2020. The ...
(Date:4/14/2015)... OXFORD, Conn. , April 14, 2015 ... "Company"), a biometric authentication company focused on the growing ... has been nominated for the 2015 New York Design ... The Design100, New York City Design Awards are ... are based on over 2,500 ratings from the marketplace, ...
Breaking Biology News(10 mins):Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 2Huntington Memorial Hospital Becomes First in the San Gabriel Valley to Offer Patients a New Heart Failure Monitoring Solution 3Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3
... 11 The following statement was,issued today by ... Affairs:, Good afternoon. I want to thank ... hospitality during our visit and for their,dedication to ... Germany., The cooperation between our two countries ...
... the University of Wisconsin School of Medicine and Public Health ... the way digits are formed. Studying the embryonic chick ... that explains how digits grow and why each digit is ... the Proceedings of the National Academy of Sciences Online Early ...
... startling discovery by scientists at the Carnegie Institution puts ... biological process on Earth. Photosynthesis by plants, algae, and ... food from sunlight, and in the process these organisms ... by Arthur Grossman and colleagues*+ reported in Biochimica et ...
Cached Biology News:Remarks Prepared for Delivery By Attorney General Michael B. Mukasey At the Ministerial Press Conference 2Wisconsin researchers describe how digits grow 2Wisconsin researchers describe how digits grow 3New twist on life's power source 2New twist on life's power source 3
(Date:4/24/2015)... Seoul Semiconductor announced the expansion ... in the lighting market. In recent months, ... technology in emerging markets such as Russia, South ... of applications such as streetlight and area lighting, ... First launched in 2005 the Acrich technology from ...
(Date:4/23/2015)... 2015 Athena San Diego, an organization ... women in San Diego’s technology and life science sectors, ... Awards at their Gala on April 30, 2015 from ... at http://athenasd.org/events/ , The Pinnacle Awards recognize ... Diego vision of fostering networking, risk taking and diversity ...
(Date:4/23/2015)... /CNW/ - A new and innovative service has won ... North America,s largest packaging trade association. ... the "Sustainability, service" category of the PAC Global ... is a service that scores clients, packaging against ... This benchmarking process shows clients how their packaging ...
(Date:4/23/2015)... D.C. (PRWEB) April 23, 2015 ... D.C. region on April 4-17 as part of ... marks the fourth group of biotechnology startups to ... of Nizhny Novgorod (UNN) and the University of ... deepen ties between their respective universities in the ...
Breaking Biology Technology:Acrich Technology from Seoul Semiconductor Adopted in Installations Worldwide 2Athena Pinnacle Awards to Honor Executives, Corporations and Educators Working to Promote Women Leaders 2U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 2U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 3U.S.-Russian Innovation Corridor Program Connects Visiting Russian Startups to U.S. Experts 4
... SAN DIEGO, Dec. 16, 2010 Gen-Probe Incorporated (Nasdaq: ... has acquired GTI Diagnostics, a privately held specialty diagnostics ... coagulation markets, for $53 million in cash. ... private equity firm, and from individual investors who include ...
... Conn., Dec. 15, 2010 HistoRx announces that Jack ... of Directors.  As the former President and CEO of ... company, he is an acknowledged diagnostic industry expert. ... Chairman of the Board at Dianon Systems, a leading ...
... performance of a brain-machine interface designed to help paralyzed subjects ... of a robotic arm providing sensory feedback, a new study ... translate brain activity into the movement of a computer cursor ... humans. But in these early systems, vision was the only ...
Cached Biology Technology:Gen-Probe Acquires GTI Diagnostics for $53 Million in Cash 2Gen-Probe Acquires GTI Diagnostics for $53 Million in Cash 3Jack Davis, Diagnostics Industry Executive, Joins the HistoRx Board of Directors 2Robot arm improves performance of brain-controlled device 2Robot arm improves performance of brain-controlled device 3