Navigation Links
Nutrient in eggs and meat may influence gene expression from infancy to adulthood
Date:9/20/2012

ntinue to have a long-lasting influence on adult life," said Eva K. Pressman, M.D., study author and director of the high-risk pregnancy program at the University of Rochester Medical Center. "While our results won't change practice at this point, the idea that maternal choline intake could essentially change fetal genetic expression into adulthood is quite novel."

Pressman, who advises pregnant women every day, says choline isn't something people think a lot about because it is already present in many things we eat and there is usually no concern of choline deficiency. Though much more research has focused on folate functionally very similar to choline and used to decrease the risk of neural tube defects like spina bifida a few very compelling studies sparked her interest, including animal studies on the role of choline in mitigating fetal alcohol syndrome and changing outcomes in Down syndrome.

A long-time collaborator with researchers at Cornell, Pressman joined a team led by Marie Caudill, Ph.D., R.D., professor in the Division of Nutritional Sciences at Cornell, in studying 26 pregnant women in their third trimester who were assigned to take 480 mg per day, an amount slightly above the standard recommendation of 450 mg per day, or about double that amount, 930 mg per day. The choline was derived from the diet and from supplements and was consumed up until delivery.

The team found that higher maternal choline intake led to a greater amount of DNA methylation, a process in which methyl groups one carbon atom linked to three hydrogen atoms are added to our DNA. Choline is one of a handful of nutrients that provides methyl groups for this process. The addition of a single methyl group is all it takes to change an individual's epigenome.

Measurements of cord blood and samples from the placenta showed that increased choline, via the addition of methyl groups, altered epigenetic markers that govern cortisol-regulating genes
'/>"/>

Contact: Emily Boynton
emily_boynton@urmc.rochester.edu
585-273-1757
University of Rochester Medical Center
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Research on flavanols and procyanidins provides new insights into how these phytonutrients may positively impact human health
2. Consumers need simple, concise messages about benefits of phytonutrients
3. Nutrient and toxin all at once: How plants absorb the perfect quantity of minerals
4. Obtaining key nutrients from canned foods can save consumers money
5. Prenatal micronutrient, food supplementation intervention in Bangladesh decreases child death rate
6. Study: No-fat, low-fat dressings dont get most nutrients out of salads
7. U OF A expert pinpoints nutrient behind fresh water algae blooms
8. Increased sediment and nutrients delivered to bay as Susquehanna reservoirs near sediment capacity
9. Circadian rhythms have profound influence on metabolic output, UCI study reveals
10. BUSM researchers identify genes that influence hippocampal volume
11. Fat outside of arteries may influence onset of coronary artery disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/28/2014)... . , How ... when times are lean? By studying wild chimpanzees in ... the Max Planck Institute for Evolutionary Anthropology in Leipzig, ... can acquire extra energy needed to maintain large, costly ... more en route to breakfast sites containing fruits that ...
(Date:10/28/2014)... moving activity in a novel environment are linked ... to an experimental study completed at the University ... Fisheries Research Institute. The study used novel, long-term ... angling trials to analyse if behaviours predict the ... traditional and enriched hatchery rearing environments. Based ...
(Date:10/27/2014)... species of the West Antarctic Peninsula (WAP), one of ... the average annual temperature in the Antarctic Peninsula has ... Celsius during winter. , As the WAP climate ... to a warmer, sub-polar system with more rain. , ... local weather conditions and the weight of Adélie penguin ...
Breaking Biology News(10 mins):The early chimp gets the fig 2The early chimp gets the fig 3Fish 'personality' linked to vulnerability to angling 2University of Delaware study connects penguin chick weights to local weather conditions 2University of Delaware study connects penguin chick weights to local weather conditions 3
... Jeremy Smith, Governor,s Chair for Molecular Biophysics ... reveal a key trigger of GerstmannStrusslerScheinker (GSS) syndrome, ... could have far-reaching implications for the treatment of ... Parkinson,s. Smith conducted his research with ...
... BeeSpace Navigator, University of Illinois researchers have created both ... approach to searching for information. The project was ... Biology and the department of computer science. Led by ... at the U. of I., the team described the ...
... Virginia Tech in Blacksburg, Va. recently found a way ... more efficient, powerful and less expensive. Specifically, they discovered ... of water or ions, which are necessary for fuel ... Nafion, a polymer electrolyte membrane, or PEM, commonly used ...
Cached Biology News:UT scientist uncovers trigger to fatal neurodegenerative disease 2New curation tool a boon for genetic biologists 2New curation tool a boon for genetic biologists 3Stretching old material yields new results for energy- and environment-related devices 2
(Date:10/27/2014)... Oct. 27, 2014 Kalorama Information says that ... concern in the United States ... healthcare market researcher said the FDA,s Emergency Use Authorization (EUA) ... tests for the detection of the Ebola virus was ... Kalorama routinely assess the IVD industry and its biennial ...
(Date:10/27/2014)... The report “Smart Highway Market by Technology (Intelligent ... by Display (Variable Message Signs, Digital Signage) - ... into various sub-segments with in-depth analysis and forecasting ... restraints for this market with insights into trends, ... and 37 figures spread through 141 pages in-depth ...
(Date:10/26/2014)... The report "Data Center Networking Market [Ethernet switches, ... Appliances]: Global Advancements, Worldwide Forecasts & Analysis (2013-2018)" ... into various segments with an in-depth analysis and ... factors driving this market, various restraints and challenges, ... roadmaps. , Browse 106 market data tables and ...
(Date:10/25/2014)... BioProcess International (BPI), a business-to-business ... BioProcess International Awards. The awards celebrate the outstanding ... technology applications that will allow the industry to ... patient base. , Winners and finalists were honored ... entertaining and exciting awards dinner and ceremony yesterday ...
Breaking Biology Technology:Kalorama: PCR The Go-to Test in Ebola Fight 2Kalorama: PCR The Go-to Test in Ebola Fight 3Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 2Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 3Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 4Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 2Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 3Data Center Networking Market by Ethernet Switches, SAN & Routers Worth $21.85 Billion by 2018 - New Report by MarketsandMarkets 4BioProcess International Announces Winners of the 2014 BioProcess International Awards 2BioProcess International Announces Winners of the 2014 BioProcess International Awards 3BioProcess International Announces Winners of the 2014 BioProcess International Awards 4BioProcess International Announces Winners of the 2014 BioProcess International Awards 5
... 21, 2012 /PRNewswire-Asia/ -- Simcere Pharmaceutical Group (NYSE: ... the development, manufacturing, and marketing of branded generic and ... report its unaudited financial results for the fourth quarter ... March 7, 2012, before the market opens in the ...
... University have developed a new method for chemically ... step toward the creation of faster, thinner, flexible ... attributes, graphene is a one-atom thick, honeycomb-shaped lattice ... Among graphene,s many possible applications is electronics: Many ...
... announced that it has held an End-of-Phase 2 meeting with ... clinical studies completed for XaraColl ® and to discuss ... Phase 3. XaraColl ® is being developed for postoperative ... in patients undergoing hernia repair. FDA agreed to the Phase ...
Cached Biology Technology:Simcere Pharmaceutical Group to Announce Fourth Quarter and Fiscal Year 2011 Financial Results on Wednesday, March 7, 2012 2A step toward better electronics 2Innocoll Announces Successful End-of-Phase 2 Meeting with FDA for XaraColl® and Agreement of the Phase 3 Program 2
Anti-ADAM-12 (Meltrin Alpha); amino terminal region; rabbit host...
Mouse monoclonal [3G8] to MDMA ( Abpromise for all tested applications)....
Fluorescein isothiocyanate (FITC) mouse anti-human IFN-alpha2 25 tests...
Rabbit Anti-melatonin (different linkage) Polyclonal Antibody...
Biology Products: