Navigation Links
Nobel Laureate Jules Hoffmann kicks off Annual Drosophila Research Conference
Date:4/4/2013

WASHINGTON, D.C. April 4, 2013 A young scientist's astute observation that grasshoppers don't get sick eventually led to profound insights into our own immunity. Jules Hoffmann, PhD, Professor of Integrative Biology at Strasbourg University, Institute of Advanced Science, France Emeritus, and 2011 Nobel Prize recipient in Physiology or Medicine is the scientist who made these insights. He described his scientific journey in the keynote lecture on April 3, 2013, the opening night of the Genetics Society of America's 54th Annual Drosophila Research Conference in Washington, D.C., April 3-7, 2013.

A father who was "an enthusiastic entomologist" and a high school biology teacher sparked Dr. Hoffmann's early interest in insects, in post-World War II Luxembourg. Later, Dr. Hoffmann marveled at the apparent ability of grasshoppers to evade infection, even when he transplanted organs among them as an undergraduate at the University of Strasbourg. How did this happen?

For his doctoral work at the Institute of Zoology in Strasbourg, France, he discovered a blood-producing tissue near the insect's heart that when damaged with X-rays, led to body-wide infection and failure to molt. After earning his PhD in experimental biology in 1969, Dr. Hoffmann pursued endocrinology for postdoctoral work. In 1978 he became director of the laboratory of endocrinology and immunology at the University of Strasbourg.

In 1990, Dr. Hoffmann's lab replaced the grasshopper with the fruit fly, Drosophila melanogaster, and moved on to a genetic dissection of antimicrobial defense. The group focused on innate immunity, the ancient arm of the immune defense that provides generalized protection against common pathogens.

"At that time, innate immunity was not considered as essential and hardly studied at all. Immunity was mainly seen in the context of antibodies and vaccination" the responses of the adaptive (acquired) immune response, he said. Innate i
'/>"/>

Contact: Phyllis Edelman
pedelman@genetics-gsa.org
301-351-0896
Genetics Society of America
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Crowdsourcing to kickstart comeback from ash dieback
2. Annual Drug Discovery Conferences Being Held in Boston MA, Spring 2012
3. Registration open for the Ecological Society of Americas 2012 Annual Meeting in Portland, Ore.
4. 5th Annual Advances in Biomolecular Engineering Symposium
5. 2012 ARVO Award recipients honored at annual meeting
6. Cracking the Neural Code: Third Annual Aspen Brain Forum
7. DOE Plasma Science Center Annual Meeting at Princeton Plasma Lab
8. 6th Annual Canadian Neuroscience Meeting, Vancouver, May 20-23, 2012
9. European Society of Human Reproduction and Embryology 28th Annual Meeting -- Istanbul
10. BioMed Central announces winners of 6th Annual Research Awards
11. John Theurer Cancer Center presents significant blood cancer research at 2012 ASCO Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/17/2014)... . To date, ... overdoses, doctors are often limited to supportive therapy such as ... combination of drugs involved. So what can be done if ... ETH professor Jean-Christophe Leroux from the Institute of Pharmaceutical Sciences ... question. "The task was to develop an agent that could ...
(Date:10/16/2014)... efficiently, they are anything but sustainable: environmental damage ... is becoming increasingly evident. Despite their disadvantages, however, ... regarded as the sole possibility of achieving higher ... Bernhard Schmid, an ecology professor at the University ... agriculture and forestry. After all, a new study ...
(Date:10/15/2014)... As our ability to assess the pandemic risk from ... developments, we must not allow ourselves to become complacent ... an international consortium of scientists. , Influenza pandemics arise ... have yet to develop widespread immunity – spreads in ... in the past 100 years, the worst of which ...
Breaking Biology News(10 mins):Emergency aid for overdoses 2Emergency aid for overdoses 3Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2
... REDWOOD CITY, Calif., Oct. 28 , WHAT: ... speak at the Dallas SecureWorld Expo in the Industry ... "Protecting the User-Led Aspect of Endpoint Security," Fulton will ... caused by end users. He will further examine how ...
... emerging for how important it is for pregnant women to ... day seem to have children who are less likely to ... from the Sahlgrenska Academy at the University of Gothenburg, ... Linkping University, which is conducting a population study called ABIS ...
... Olympus, a precision technology leader creating innovative opto-digital ... today announced the availability of VisiGlide 1 , its ... Terumo Corporation 2 to facilitate ERCP procedures ... of the bile and pancreatic ducts, the new 0.025 ...
Cached Biology News:DigitalPersona to Speak at Dallas SecureWorld Expo 2Vegetables can protect unborn child against diabetes 2Olympus introduces the VisiGlide, a single-use guidewire 2
(Date:10/22/2014)... 22, 2014 Involution Studios , ... of a new infographic, Understanding Ebola . ... beautifully designed, easy to follow informative tool for anyone ... outbreak, symptoms and prevention. , "As the news has ... 2014 Ebola outbreak represents not only a healthcare crisis ...
(Date:10/22/2014)... October 22, 2014 Grace Century, a ... healthcare projects, announces the addition of Dr. Yousef ... its advisory team. Dr. Siddiqui will provide further healthcare ... A graduate of University College Medical School ... in medicine in 2001. With further certification as a ...
(Date:10/22/2014)... 22, 2014   Synthetic Biologics, Inc. (NYSE ... for serious infections and diseases, announced today that the ... of Allowance for a composition of matter patent application ... program, SYN-004. This is Synthetic Biologics, first allowed ... and adds to the Company,s extensive C. difficile ...
(Date:10/22/2014)... Research and Markets  has announced the addition of ... Geography - Global Analysis and Forecast (2014 - 2020)" ... electronics, also called as polymer electronics or plastic electronics, ... small conductive molecules and electrically conductive polymers. It is ... carbon based, made using synthetic strategies developed in the ...
Breaking Biology Technology:Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2Dr. Yousef Siddiqui joins the Grace Century Advisory Team 2Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 2Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 3Synthetic Biologics Announces Allowance of Key U.S. Composition of Matter Patent for C. difficile Program 4Global Organic Electronics (Semiconductor, Conductive, Dielectric and Substrate) Market - Analysis and Forecast (2014 - 2020) 2Global Organic Electronics (Semiconductor, Conductive, Dielectric and Substrate) Market - Analysis and Forecast (2014 - 2020) 3
... reveal critical evidence, as well as an identity, with ... University that detects trace amounts of explosives, drugs or ... new technology also can distinguish between overlapping fingerprints left ... optical forensic methods. , A team led by R. ...
... Brazil, Sept. 23 A bill designed to,strengthen ... by,the U.S. Senate Foreign Relations Committee, is a ... the United States to promote the production,and use ... the,Brazilian Sugarcane Industry Association (UNICA)., "It shows ...
... 23 Pressure,BioSciences, Inc. (Nasdaq: PBIO ... the Company,s pressure cycling technology ("PCT") was ... Fifth International Conference on,High Pressure Bioscience and ... San Diego, CA. The HPBB Conference was ...
Cached Biology Technology:Fingerprints provide clues to more than just identity 2New Bill to Expand Promotion of Biofuels Is a Welcome Boost for U.S.-Brazil Relations According to Brazilian Sugarcane Industry 2New Bill to Expand Promotion of Biofuels Is a Welcome Boost for U.S.-Brazil Relations According to Brazilian Sugarcane Industry 3Pressure Cycling Technology (PCT) Highlighted in Five Podium Presentations at the Fifth International Conference on High Pressure; PBI Introduces the Patent-pending 'PCT Shredder' at the Meeting 2Pressure Cycling Technology (PCT) Highlighted in Five Podium Presentations at the Fifth International Conference on High Pressure; PBI Introduces the Patent-pending 'PCT Shredder' at the Meeting 3Pressure Cycling Technology (PCT) Highlighted in Five Podium Presentations at the Fifth International Conference on High Pressure; PBI Introduces the Patent-pending 'PCT Shredder' at the Meeting 4
Tan solid. A glycoside used to permeabilize cellular membranes. Exhibits hemolytic activity. Contaminants: ash: ≤10%. Soluble in H 2 O. pH 4.4 - 4.6. RTECS VQ1400000, CAS 8047-15-2. References:...
Anti Autotaxin /ENPP2 , - (Rabbit)...
... 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose Pale yellow solid. An N-nitroso-containing ... nitric oxide donor in pancreatic islets. ... Causes DNA alkylation and DNA strand ... ≥95% by HPLC. Soluble in H ...
Mouse monoclonal antibody to CDC2L5 - cell division cycle 2-like 5 (cholinesterase-related cell division controller)...
Biology Products: