Navigation Links
New tuberculosis drug trial begins in South Africa
Date:12/11/2012

ve bacteria and mycobacteria; they work by stopping the creation of proteins that are essential to bacteria's survival. AZD5847 is active in culture against a broad array of drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis, which causes TB.

"AZD5847 is one part of AstraZeneca's ongoing commitment to conducting research and collaborating across industry, academia, and government to develop novel treatments for TB and help stop the spread of the disease," said Manos Perros, head of the AstraZeneca Infection Innovative Medicines Unit. "AstraZeneca's intent is to work with partners to test the contribution of AZD5847 in Phase 2b trials as part of one or more next-generation combination therapies."

Combating TB is one of the United Nations' Millennium Development goals . The most recent TB drugs were introduced in the 1960s. Since then, some strains have developed resistance to those medications. Drug-resistant TB requires up to two years of treatment with more expensive second-line drugs that have more side effects. Many patients with drug-resistant TB go untreated in endemic countries due to a lack of medical resources. The World Health Organization estimates that 220,000 to 400,000 multi-drug resistant TB cases occurred among TB cases in 2011. About 60 percent of these cases were reported in Brazil, China, India, the Russian Federation and South Africa.


'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Biosignatures distinguish between tuberculosis and sarcoidosis
2. Targeting tuberculosis hotspots could have widespread benefit
3. MIT-designed cooler preserves tuberculosis drugs, records doses
4. Research on improvements in diagnosing and treating tuberculosis
5. Millions of diabetics could die of tuberculosis
6. New approach of resistant tuberculosis
7. Iowa State, Ames Lab researchers study the structure of drug resistance in tuberculosis
8. High doses of Vitamin D help tuberculosis patients recover more quickly
9. Scientists reveal how natural antibiotic kills tuberculosis bacterium
10. Notre Dame research could provide new insights into tuberculosis and other diseases
11. Missing link discovered in the defence mechanism of the tuberculosis pathogen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2015)... NEW YORK , Sept. 2, 2015 ... key concern for enterprises, banks, government organizations, telecommunication and ... and assets. Keys, identity badges, and numeric keypads are ... with the structure of palm and fingers of an ... palm. Hand geometry scanners with infrared light and reflectors ...
(Date:9/2/2015)... , Sept. 2, 2015 Security ... concern for enterprises, banks, government organizations, telecommunications, hospitals, ... numeric keypads were previously being used to prevent ... of two-factor authentication, wherein individuals could gain access ... different components, such as hardware devices and numeric ...
(Date:9/2/2015)... September 2, 2015 ... implied in a system which uses identical human ... iris, vein, DNA and finger print. Increasing number ... develop such system which provides high level of ... Patterns and tokens are vulnerable to attacks. Furthermore, ...
Breaking Biology News(10 mins):Global Hand Geometry Biometrics Market 2015-2019 2Global Hand Geometry Biometrics Market 2015-2019 3Global Biometrics Spending Market in the Government Sector 2015-2019 2Global Biometrics Spending Market in the Government Sector 2015-2019 3Biometrics Technology Market is Expected to Reach $13.8 Billion by 2015: Hexa Research Inc. 2Biometrics Technology Market is Expected to Reach $13.8 Billion by 2015: Hexa Research Inc. 3Biometrics Technology Market is Expected to Reach $13.8 Billion by 2015: Hexa Research Inc. 4
... a reason to be afraid of the dark. ... the light of the water,s surface become proverbial "fish out ... found in caves, according to a study from North Carolina ... Biology Letters, a Royal Society scientific journal, NC State ...
... The Wildlife Conservation Society,s Bronx Zoo veterinarians, U.S. Fish ... Environmental Conservation, and the Massachusetts Natural Heritage and Endangered ... wildlife question: Why are bog turtles getting sick? ... turtle; an adult bog turtle reaches only 4.5 inches ...
... for food is soaring along with the world,s population, ... is becoming increasingly diminished and unreliable. Fortunately, it,s ... it will take, say the editors and contributors to ... for Agriculture, is rediscovering the value of soil management ...
Cached Biology News:Darkness stifles reproduction of surface-dwelling fish 2Smallest turtle in the land becomes more scarce 2Rediscovering sound soil management 2
(Date:9/3/2015)... ... , ... If you plan to attend the 27th annual Tradeline College ... to sign up for the tour of Framingham State University's newest addition to Hemenway ... of the (8) chemistry teaching labs that are exclusively utilizing (49) filtered fume ...
(Date:9/2/2015)... Mich. and LIBERTYVILLE, Ill. (PRWEB) , ... ... ... NSF International, a leading provider of regulatory compliance, quality systems, analytical testing, ... LLC, a consulting firm with expertise in medical device products/processes development, design ...
(Date:9/2/2015)... (PRWEB) , ... September 02, 2015 , ... ... treated and managed with the use of special anti-vascular endothelial growth factor agents ... many more patients, currently does not have a scientific protocol for the many ...
(Date:9/2/2015)... 02, 2015 ... announced the addition of Jain PharmaBiotech,s new ... Companies" to their offering. ... besides fluorescence in situ hybridization (FISH), comparative ... cytogenetics includes application of nanobiotechnology, microarrays, real-time ...
Breaking Biology Technology:Erlab Invites You to Tour the Largest Installation of Filtered Fume Hoods in the World 2NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 2NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 3NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 4NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 5NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 6NSF International Strengthens Medical Device Consulting With Acquisition of Avarent LLC 7StemCell GeneticMed Announces That It Has Started Stem Cell Treatments for Age Related Dry Macular Degeneration (AMG) 2Global Cytogenetics Technologies Study 2015-2025 - Latest Markets and Companies Analysis 2Global Cytogenetics Technologies Study 2015-2025 - Latest Markets and Companies Analysis 3
... was paired with a pitch to produce more alcohol fuel, ... whether Wisconsin can overcome a late start to become a ... engineered plants to create fuel, fiber, plastics and chemicals may ... ,The war in Iraq and a near-doubling of gasoline ...
... a cardinal rule with his graduate students: "If you want ... Wisconsin-Madison anthropologist practices what he preaches, deciding in 2005 not ... world via academic weblog. , ,The result is John Hawks.net ... also happened to evolve a life - and audience - ...
... business and IT consultancy with a significant Wisconsin presence, ... undisclosed terms. , ,Howard Blietz and Eric Wasowicz, Greenbrier ... senior executive roles. A Fujitsu company statement said that ... the company in their current roles for now to ...
Cached Biology Technology:Wisconsins promising bio-refining future wont run on ethanol alone 2Wisconsins promising bio-refining future wont run on ethanol alone 3Anthropology professor's blog raises public interest 2Anthropology professor's blog raises public interest 3
The SVT3-2 diverter valve is a 3-port, 2-position valve for use with the BioLogic DuoFlow system....
... The PROTEAN II XL cell, wide format, is used ... x 20 cm gels and requires 1.2 L of ... unit and the 2.0 mm IPG conversion kit, which ... and includes 2 sets of IPG clamps, 2 sets ...
... been developed with the drug discovery process ... sensitivity and performance, Safire is the ideal ... development and high throughput screening. Safire is ... that offers a range of high speed ...
F40 piston seals are supplied as 2 seals with a seal tool to service one F40 pump of a BioLogic DuoFlow workstation....
Biology Products: