Navigation Links
New tuberculosis drug trial begins in South Africa
Date:12/11/2012

ve bacteria and mycobacteria; they work by stopping the creation of proteins that are essential to bacteria's survival. AZD5847 is active in culture against a broad array of drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis, which causes TB.

"AZD5847 is one part of AstraZeneca's ongoing commitment to conducting research and collaborating across industry, academia, and government to develop novel treatments for TB and help stop the spread of the disease," said Manos Perros, head of the AstraZeneca Infection Innovative Medicines Unit. "AstraZeneca's intent is to work with partners to test the contribution of AZD5847 in Phase 2b trials as part of one or more next-generation combination therapies."

Combating TB is one of the United Nations' Millennium Development goals . The most recent TB drugs were introduced in the 1960s. Since then, some strains have developed resistance to those medications. Drug-resistant TB requires up to two years of treatment with more expensive second-line drugs that have more side effects. Many patients with drug-resistant TB go untreated in endemic countries due to a lack of medical resources. The World Health Organization estimates that 220,000 to 400,000 multi-drug resistant TB cases occurred among TB cases in 2011. About 60 percent of these cases were reported in Brazil, China, India, the Russian Federation and South Africa.


'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Biosignatures distinguish between tuberculosis and sarcoidosis
2. Targeting tuberculosis hotspots could have widespread benefit
3. MIT-designed cooler preserves tuberculosis drugs, records doses
4. Research on improvements in diagnosing and treating tuberculosis
5. Millions of diabetics could die of tuberculosis
6. New approach of resistant tuberculosis
7. Iowa State, Ames Lab researchers study the structure of drug resistance in tuberculosis
8. High doses of Vitamin D help tuberculosis patients recover more quickly
9. Scientists reveal how natural antibiotic kills tuberculosis bacterium
10. Notre Dame research could provide new insights into tuberculosis and other diseases
11. Missing link discovered in the defence mechanism of the tuberculosis pathogen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/28/2014)... National University of Singapore (NUS) have discovered a new ... laying direct developing eggs in live bamboo with narrow ... bush frog ( Raorchestes chalazodes ). This critically ... known to adopt this novel reproductive strategy. The findings ... Biological Journal of the Linnean Society , in October ...
(Date:10/28/2014)... University Singapore (NTU Singapore) will be building a ... energy sources. , The first in the region, ... integration of solar, wind, tidal-current, diesel, storage and ... well together. , To be built under the ... the hybrid micro-grid will be located offshore at ...
(Date:10/27/2014)... a scientific one-two punch with a pair of papers ... sticky ends. , Collagen is the most common protein ... fibrous tissues that support cells and hold organs together. ... for tissue engineering and cosmetic and reconstructive medicine. , ... synthetic collagen for a decade, teasing out the details ...
Breaking Biology News(10 mins):NUS researchers discover for the first time that a rare bush frog breeds in bamboo 2NUS researchers discover for the first time that a rare bush frog breeds in bamboo 3NTU to build region's first renewable energy integration demonstration micro-grid 2NTU to build region's first renewable energy integration demonstration micro-grid 3'Sticky' ends start synthetic collagen growth 2'Sticky' ends start synthetic collagen growth 3
... year in the Horn of Africa affected millions of people ... of several migratory songbird species, a study from University of ... the migration route was revealed by data collected from small ... an extended stay in the Horn of Africa. , The ...
... Entomologist Marshall Johnson , an extension specialist and ... the Distinguished Scientist of the Year Award from the ... (IOBC-NRS). Only one individual is recognized annually for ... career in the nearctic region , which encompasses ...
... DNA self-assembly techniques, researchers have developed a new ... the time required to create and test medications. ... Foundation (NSF) Small Business Innovation Research grant, researchers ... and began evaluating a drug for combating the ...
Cached Biology News:Drought in the Horn of Africa delays migrating birds 2UC Riverside entomologist named Distinguished Scientist of the Year 2Drag-and-drop DNA 2Drag-and-drop DNA 3Drag-and-drop DNA 4
(Date:10/30/2014)... 30, 2014 Avure Technologies celebrates a year ... newest member of its fleet of high volume High Pressure ... anniversary as we return to PackExpo this year, which is ... Las Vegas,” said Jeff Williams, CEO at Avure. “Sales of ... pleased to be meeting the challenges of market demand for ...
(Date:10/30/2014)... challenges in the development of quantum technologies has been ... paper published today (28 October) in Nature Communications ... make a new type of flexibly designed microscopic trap ... sensors and specialised superfast computers, often depend on harnessing ... trapping these tiny particles are hugely problematic because of ...
(Date:10/27/2014)... TORONTO , Oct. 27, 2014 /PRNewswire/ ... GNBT) today announced two presentations demonstrating that the ... novel proprietary cancer immunotherapeutic AE37 vaccine correlated with ... The AE37 cancer vaccine is being developed by ... www.antigenexpress.com ). The presentations are being made at ...
(Date:10/27/2014)... The report “Smart Highway Market by Technology ... and by Display (Variable Message Signs, Digital Signage) ... market into various sub-segments with in-depth analysis and ... and restraints for this market with insights into ... tables and 37 figures spread through 141 pages ...
Breaking Biology Technology:In High Demand: New High Pressure Processing (HPP) System with Maximum Throughput Drives Strong Sales 2In High Demand: New High Pressure Processing (HPP) System with Maximum Throughput Drives Strong Sales 3Generex Announces Presentations Correlating Immunological Response with Reduced Recurrence in Phase II Study of AE37 Breast Cancer Vaccine in Patients at the American College of Surgeons 2Generex Announces Presentations Correlating Immunological Response with Reduced Recurrence in Phase II Study of AE37 Breast Cancer Vaccine in Patients at the American College of Surgeons 3Generex Announces Presentations Correlating Immunological Response with Reduced Recurrence in Phase II Study of AE37 Breast Cancer Vaccine in Patients at the American College of Surgeons 4Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 2Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 3Smart Highway Market by Technology, and Display Expected to Reach $27.992.0 Million by 2019- New Report by MarketsandMarkets 4
... , , WILMINGTON, Del., ... dispersible tablet (ODT) technologies with its patented Pharmaburst(R) and Pharmafreeze(TM) ... proprietary technology with superior organoleptics, Pharmaburst(R) 500 will most certainly ... formulators have come to expect from a quick-dissolve dosage form. ...
... WALTHAM, Mass., Aug. 11 Decision Resources, one of ... issues, finds that the entry and uptake of premium-priced biologics will ... from approximately $420 million in 2008 to nearly $2 billion in ... Systemic Lupus Erythematosus finds that the primary drivers of ...
... COLUMBIA, Md., Aug. 11 BP and Martek Biosciences ... a Joint Development Agreement (JDA) to work on the production of ... platform and operational capabilities to advance the development of a step-change ... , Under the terms of the multi-year agreement, Martek ...
Cached Biology Technology:Biologic Agents Will Drive the Systemic Lupus Erythematosus Drug Market to More Than Quadruple to Nearly $2 Billion in 2018 2BP and Martek Biosciences Enter a Joint Development Agreement to Deliver Advanced Biodiesels 2BP and Martek Biosciences Enter a Joint Development Agreement to Deliver Advanced Biodiesels 3BP and Martek Biosciences Enter a Joint Development Agreement to Deliver Advanced Biodiesels 4
Preparation TW--Compatibility: no end cap seals -Hybridization Tube for Hybrigene -Comp Dim: 240 80 mm -Material: borosilicate glass -Mfr Desig: Techne FHB-15...
...
... For use in hybridization incubators ... and GL 45 size PP plug-seal ... seal. Available in three lengths to ... plug-seal caps and O-rings available separately. ...
... extraction of DNA from agarose gels The SpinPrep ... of 150 bp to > 12,000 bp in size ... dissolve the gel slice, followed by adsorption of the ... format. After a wash step, the purified DNA is ...
Biology Products: