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New technique for developing drugs to treat serious illnesses
Date:11/14/2013

used to treat inflammation and other conditions."

The work, being published in the Journal of Biological Chemistry, was funded by the Biotechnology and Biological Sciences Research Council (BBSRC), MRC and the Wellcome Trust. The Leicester team collaborated principally with Dr Julian Sale at the MRC Laboratory of Molecular Biology in Cambridge, with additional input from Dr Hiroshi Arakawa in Italy and Dr Jean-Marie Buerstedde at Yale.

Professor Brindle said: "We are really excited about getting this technique to work and are already using it to make other new molecules that we think will be useful to people. It was a real bonus for us to be able to evolve the ligand trap using the technique as this trap targets a molecule that is involved in a whole range of health problems."


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Contact: Nick Brindle
npjb1@mail.cfs.le.ac.uk
01-162-297-170
University of Leicester
Source:Eurekalert  

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