Navigation Links
New technique captures chemical reactions in a single living cell at unprecedented resolution
Date:11/19/2007

Berkeley -- Bioengineers at the University of California, Berkeley, have discovered a technique that for the first time enables the detection of biomolecules' dynamic reactions in a single living cell.

By taking advantage of the signature frequency by which organic and inorganic molecules absorb light, the team of researchers, led by Luke Lee, professor of bioengineering and director of UC Berkeley's Biomolecular Nanotechnology Center, can determine in real time whether specific enzymes are activated or particular genes are expressed, all with unprecedented resolution within a single living cell.

The technique, described in the Nov. 18 issue of the journal Nature Methods, could lead to a new era in molecular imaging with implications for cell-based drug discovery and biomedical diagnostics.

The researchers point out that other techniques, such as nuclear magnetic resonance, can at best provide information about a cluster of cells. But to determine the earliest signs of disease progression or of stem cell proliferation, it's necessary to drill down deeper to the molecular dynamics within a single cell.

To study the biochemical processes of a cell, scientists currently cut through its outer membrane to separate and analyze the cellular components. That method can never provide a real-time view of how components function together because the cell is killed in the process of extracting its components.

"Until now, there has been no non-invasive method that exists that can capture the chemical fingerprints of molecules with nanoscale spatial resolution within a single living cell," said Lee, who is also the co-director of the Berkeley Sensor and Actuator Center. "There is great hope that stem cells can one day be used to treat diseases, but one of the biggest challenges in this field is understanding exactly how individual cells differentiate. What is happening inside a stem cell as it develops into a heart muscle inst
'/>"/>

Contact: Sarah Yang
scyang@berkeley.edu
510-643-7741
University of California - Berkeley  
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New technique can be breakthrough for early cancer diagnosis
2. University of Leicester scientists discover technique to help friendly bacteria
3. New technique reveals subtle force-induced changes in biomolecules conformation
4. New magnetic separation technique might detect multiple pathogens at once
5. Amber specimen captures ancient chemical battle
6. New light trap captures larval stage of new species; DNA barcode technology used
7. Cold Spring Harbor Protocols highlights a method that captures cell growth and activity
8. Green tea boosts production of detox enzymes, rendering cancerous chemicals harmless
9. American Chemical Societys Weekly PressPac -- Aug. 8, 2007
10. Thermochemical process converts poultry litter into bio-oil
11. New chemically-sensitive MRI scan may bypass some invasive diagnostic tests in next decade
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New technique captures chemical reactions in a single living cell at unprecedented resolution
(Date:8/5/2015)... New York , August 5, 2015 ... market report titled "Facial Recognition Market - Global Industry ... 2022", the global market for facial recognition is forecast ... is driven by increased demand for surveillance systems by ... the rising number of crimes and terrorist activities across ...
(Date:8/3/2015)... Calif. , Aug. 3, 2015 Synaptics, ... human interface solutions, today announced that members of the ... at the Pacific Crest Global Technology Leadership Forum on ... The conference will be held at the Sonnenalp Resort ... The presentation may include forward-looking information. An audio ...
(Date:7/31/2015)... Chine, 31 juillet 2015 La 10e ... ) sera organisée par le BGI du 22 ... en Chine. La conférence ... inauguration en 2006, l,ICG est devenue l,une des ... domaine des « omiques » et c,est aussi la plus ...
Breaking Biology News(10 mins):Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 2Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 3Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 4Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 5Facial Recognition Market Expected to Reach US$ 2.67 Bn by 2022, at a CAGR of 9.5% From 2015 - 2022: Transparency Market Research 6La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 2La 10e International Conference on Genomics (ICG-10) doit s'ouvrir en octobre 3
... In an era of widespread genetic sequencing, the ability ... way to explore the information within and how it guides ... WisconsinMadison in the August issue of the journal GENETICS ... flies, demonstrating a remarkable level of fine control and, importantly, ...
... , Aug. 22, 2013   Valid USA continues ... announcement today that it has acquired ScreenCheck North ... and is the worldwide exclusive licensee for Polaroid ® ... and expertise to provide AAMVA compliant Real ID solutions. ...
... 2013) Multipotent fetal dermal cells (MFDCs) may be ... tissues and organs. Their performance is superior to that ... Italy that developed a cell isolation technique for MFDCs ... early e-publication for the journal Cell Transplantation , ...
Cached Biology News:Unprecedented control of genome editing in flies promises insight into human development, disease 2Unprecedented control of genome editing in flies promises insight into human development, disease 3Valid USA Continues Growth with Acquisition of ScreenCheck North America 2Fetal tissue-derived stem cells may be ideal source for repairing tissues and organs 2
(Date:8/31/2015)... , Aug. 31, 2015 Research and ... the "Middle East & Africa Biomedical Sensors Market ... their offering. The Middle ... estimated at $0.84 billion by 2018 at a CAGR ... near future will bring Biomedical sensors that are adaptable ...
(Date:8/31/2015)... SHANGHAI , Aug. 31, 2015  MicuRx ... antibiotics, today announced positive top-line results from the ... drug candidate MRX-I. MRX-I is an oral oxazolidinone ... MRSA and VRE, while offering physicians and patients ... currently available oxazolidinone agents. "These ...
(Date:8/31/2015)... Tampa, FL (PRWEB) , ... August 31, 2015 ... ... will bring together the world's most successful food and beverage processors, equipment manufacturers ... its competencies in product inspection and industrial weighing and formulation for manufacturers of ...
(Date:8/28/2015)... -- According to a new market research ... Thawing Equipment, Alarms), by Biospecimen (Human Tissue, Stem Cells, ... - Global Forecast to 2020", published by MarketsandMarkets, the ... Million by 2020 from USD 2,150.48 Million in 2015, ... 2020. Browse 74 Tables and 95 ...
Breaking Biology Technology:Middle East & Africa Biomedical Sensors Market Report 2015 - Growth, Trends & Forecasts to 2020 2MicuRX Reports Positive Top-Line Results In Phase 2 Clinical Trial For Novel Antibiotic MRX-I In Complicated Skin And Soft Tissue Infections 2METTLER TOLEDO Hosts Food Safety Educational Center at 2015 PROCESS EXPO 2Biopreservation Market Worth 3,731.03 Million USD by 2020 2Biopreservation Market Worth 3,731.03 Million USD by 2020 3Biopreservation Market Worth 3,731.03 Million USD by 2020 4Biopreservation Market Worth 3,731.03 Million USD by 2020 5
... Dec. 4 Vivakor, Inc. (OTC Bulletin Board: VIVK) today ... will receive the dividend of shares of common stock of ... Directors. HealthAmerica is a private Nevada corporation of which ... the record date. The distribution date is still expected to ...
... Dec. 4 Stemline Therapeutics, Inc. today announced that data from ... both in vitro and animal models of human chronic ... upcoming 51st Annual Meeting of the American Society of Hematology (ASH), ... poster will be presented by Stemline,s collaborators at The University of ...
... , , HOUSTON, ... that it has updated its facility to offer patients a second ... LAP-BAND® System that it currently performs. The first sleeve gastrectomy ... St. Laurent, MD on October 20, 2009. The patient is ...
Cached Biology Technology:Vivakor Confirms Record Date of Stock Dividend 2Vivakor Confirms Record Date of Stock Dividend 3Stemline Therapeutics Announces Poster Presenting in vivo and Anti-Cancer Stem Cell Activity of SL-401 against Chronic Myeloid Leukemia (CML) at the 51st Annual Meeting of the American Society of Hematology (ASH) 2JourneyLite of Houston Now Offering Sleeve Gastrectomy 2
...
A component of the Acridinium protein labeling kit....
... real-time PCR detection system holds 48 x 0.2 ... of 48 LEDs independently excites fluorescence (470-500 nm) ... photodiodes detects emitted light (523-543 nm and 540-700 ... Mini cycler, whose Peltier heat pumps provide superb ...
... up to 6 strain chambers with precise uniaxial ... design ensures that cells grow over long periods ... This unit allows you to control the frequency ... unique strain settings. The instrument fits in a ...
Biology Products: