Navigation Links
New software traces origins of genetic disorders 20 times more accurately
Date:10/23/2013

In a bioinformatics breakthrough, iMinds STADIUS KU Leuven researchers have successfully applied advanced artificial intelligence to enable the automated analysis of huge amounts of genetic data. Their new software suite, eXtasy, automatically generates the most likely cause of a given genetic disorder. The breakthrough directly impacts the treatment of millions of people with a hereditary disease.

At least 5% of the world population suffers from a rare, hereditary disease. Until recently, the origins of these genetic disorders could be correctly identified in only half of all cases. The lack of a conclusive diagnosis prolongs uncertainty for both the patients and their families and marks the beginning of a long search, and expensive, strenuous and even unnecessary treatments.

The introduction of new, cheaper technologies for deciphering the human genome held the promise of a quicker and more accurate diagnosis of hereditary diseases. But this proved challenging particularly because of the huge amount and complexity of the data to be processed.

The genomes of two healthy individuals show no less than four million differences or mutations. Most of these mutations are harmless, but just one extra, malignant mutation can be enough to cause a genetic anomaly. Existing analytical methods simply do not have the means to reliably and quickly find this needle in the haystack.

The eXtasy software suite developed by iMinds STADIUS KU Leuven researchers drastically changes this outlook. The program can trace the origins of genetic disorders twenty times more accurately than existing analytical methods.

"eXtasy uses advanced artificial intelligence to combine whole sets of complex data into a global score that reflects how important a certain mutation is for a certain disease. This data can consist of networks of interacting proteins, but could also include scientific publications or even scores that estimate how harmful
'/>"/>

Contact: Dr. Ir. Yves Moreau
yves.moreau@esat.kuleuven.be
32-163-21075
KU Leuven
Source:Eurekalert

Page: 1 2

Related biology news :

1. DigitalPersona Expands Secure Banking Solutions Portfolio with Software Acquisition
2. QUT develops software to reduce greenhouse gases
3. BioClaim, Inc. Signs Biometric Software Contract with Amerigroup Florida
4. Researchers develop software tool for cancer genomics
5. Neurotechnology Announces NCheck Bio Attendance 2.0 Biometric Time and Attendance Software
6. Iris Biometrics Leader, EyeLock, Redefines Identity Authentication, Announces Availability of Software Development Kit to Accelerate Deployment of Technology
7. DigitalPersona Announces U.are.U Software Development Kit (SDK) for Android Applications
8. Identify Security Software to Make Cyberspace Secure Once And For All
9. Hyland Software Partners with Communication Intelligence Corporation (CIC), a Leading Supplier of Electronic Signature Solutions
10. Medbox Partners with Bio-Tech Medical Software to Create Nations Safest Prescription Drug and Medical Marijuana Distribution System
11. Crank Software Selects TREW Marketing for Embedded Industry Outreach
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... has its own bacterial identity. That,s the conclusion of ... who studied the genetic fingerprints of bacteria on 57 ... "This study demonstrates for the first time that host ... strategies possess very different microbial communities on their leaves," ... researcher in the UO,s Institute of Ecology and Evolution ...
(Date:9/16/2014)... The fall marks a new school year, a new ... International Space Station. In September, SpaceX,s Dragon spacecraft is ... supplies and investigations as part of the company,s fourth ... cargo will be the third suite of research investigations ... in Space (CASIS). With the role of managing the ...
(Date:9/16/2014)... years after the Hesperides vessel returned to Spain culminating ... have an increasingly clear picture of how the global ... the input of pollutants from the atmosphere is not ... most remote areas of the planet, and it is ... are presented this week in CSIC Residence for Researchers ...
Breaking Biology News(10 mins):Microbiome research shows each tree species has a unique bacterial identity 2CASIS research set for launch aboard SpaceX mission to space station 2CASIS research set for launch aboard SpaceX mission to space station 3The Malaspina Expedition confirms that pollution reaches even the most remote areas of the ocean 2The Malaspina Expedition confirms that pollution reaches even the most remote areas of the ocean 3
... CORVALLIS, Ore. The soils in large areas of the ... America, have been drying up in the past decade, a ... ever examine "evapotranspiration" on a global basis. Most climate ... water from the land to the atmosphere, would increase with ...
... 9, 2010 Help may be on the way for ... the invasion of stink bugs. Scientists have reported a key ... stinkbugs, which are emerging as a major nuisance to homeowners ... a natural substance in a fungus that infects a common ...
... have reported direct evidence that taking up smoking results in ... results were reported at the 35th Congress of the European ... link between smoking and cancer has been established for decades, ... Institute of Cancer Studies, Birmingham, who presented the results. Smoking ...
Cached Biology News:Land 'evapotranspiration' taking unexpected turn: huge parts of world are drying up 2Land 'evapotranspiration' taking unexpected turn: huge parts of world are drying up 3Progress toward first commercial repellent for East Coast's stinker 2Study reveals cancer-linked epigenetic effects of smoking 2
(Date:9/16/2014)... 2014  Biocom, the association representing the ... 9 th Annual National Health Information Technology Week, ... in improving our health care system. ... the world,s most vibrant hubs for health IT and ... to genomic testing to remote patient monitoring," said ...
(Date:9/16/2014)... From cell phones to cars and flashlights, batteries ... and technology companies constantly are seeking ways to ... first time using a water-based solution, researchers at ... and more efficient nuclear battery that could be ... energy source in automobiles and also in complicated ...
(Date:9/16/2014)... BlueInGreen® , a water quality ... delivering dissolved gases into liquids, announced the addition ... manufacturer’s representative firm to its sales network. H2Flow ... water and wastewater applications in the Canadian provinces ... in 1992 and serves Quebec and Ontario markets ...
(Date:9/16/2014)... , Sept. 16, 2014  Donald Fresne, President and ... of Stephan Vagner , PhD to its Scientific Advisory ... of Toulouse, France , performed research at ... , and at Inserm, the French institute of health and ... works both at the Curie Institute, Orsay, France ...
Breaking Biology Technology:Biocom Recognizes National Health IT Week 2BlueInGreen® Expands into Canada – Signs Representative Agreement with H2Flow Equipment Inc. 2New Appointment to the Scientific Advisory Committee at Egenix, Inc. 2
... , , , ... RA (TM), a new online talk show hosted by award-winning journalist and ... , , To view the Multimedia News Release, go ... ) , , New Way RA ...
... , SCOTTSDALE, Ariz., July 29 ... subsidiary of IR BioSciences Holdings, Inc. (OTC Bulletin Board: IRBS), ... is both active on oral administration and provides therapeutic effects ... Preliminary analysis of ongoing bioavailability studies in rats ...
... , , SOUTH SAN FRANCISCO, Calif., ... reported financial results for the second quarter ended June 30, 2009. , ... was $3.5 million, with a net loss of $22.9 million, including non-cash ... from operations was $1.9 million for the second quarter and $10.2 million ...
Cached Biology Technology:Video: New Way RA(TM) Talk Show Premieres Online for People Living With Rheumatoid Arthritis (RA) 2Video: New Way RA(TM) Talk Show Premieres Online for People Living With Rheumatoid Arthritis (RA) 3Video: New Way RA(TM) Talk Show Premieres Online for People Living With Rheumatoid Arthritis (RA) 4ImmuneRegen BioSciences Confirms Homspera's Therapeutic Anti-Influenza Effect on Pandemic H1N1 Influenza Virus After Oral Administration 2ImmuneRegen BioSciences Confirms Homspera's Therapeutic Anti-Influenza Effect on Pandemic H1N1 Influenza Virus After Oral Administration 3Sunesis Reports Financial Results for the Second Quarter 2009 2Sunesis Reports Financial Results for the Second Quarter 2009 3Sunesis Reports Financial Results for the Second Quarter 2009 4Sunesis Reports Financial Results for the Second Quarter 2009 5Sunesis Reports Financial Results for the Second Quarter 2009 6Sunesis Reports Financial Results for the Second Quarter 2009 7Sunesis Reports Financial Results for the Second Quarter 2009 8Sunesis Reports Financial Results for the Second Quarter 2009 9Sunesis Reports Financial Results for the Second Quarter 2009 10Sunesis Reports Financial Results for the Second Quarter 2009 11
... Synthesis Service provides you with ... knockdown any gene. We offer ... pairs with terminal dT nucleotides), ... lengths of your choice. Each ...
... System is ideal for developing single and ... system contains the new, improved, and user ... user can design specific templates for commercial ... fully integrated graphing and data regression capabilities; ...
Polyclonal Antibody to HADHB...
3T3 cells (RSV-transformed) Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
Biology Products: