Navigation Links
New sickle cell anemia therapy advances to Phase II clinical trials
Date:6/12/2013

sed in patients too ill to undergo exercise stress testing using a treadmill. It is given in brief (10 seconds), intravenous doses.

In Phase I of the trial, a dose escalation safety study, participants received very low doses of Lexiscan administered by continuous intravenous infusion, over 12 or 24 hours, to suppress inflammation. Following this initial study of adults with sickle cell anemia not experiencing pain crises, Phase II of the trial will expand to include patients experiencing pain crises and acute chest syndrome, and children over 14. Dr. Linden adds that Phase II will be a placebo-controlled trial.


'/>"/>

Contact: Bonnie Ward
contact@liai.org
619-303-3160
La Jolla Institute for Allergy and Immunology
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Sickle cell trait can cause sudden cardiac death in black athletes: Why is this controversial?
2. Potential gene therapy approach to sickle cell disease highlighted at ASH
3. Nature study reveals loss of essential blood cell gene leads to anemia
4. Why a hereditary anemia is caused by genetic mutation in mechanically sensitive ion channel
5. Cleveland Clinic research shows anemia drug does not improve health of anemic heart failure patients
6. Discovery may help prevent chemotherapy-induced anemia
7. Scientists identify potential drug target for treatment-resistant anemias
8. Stanford scientists develop gene therapy approach to grow blood vessels in ischemic limbs
9. Ottawa researchers to lead world-first clinical trial of stem cell therapy for septic shock
10. New insight into mechanisms behind autoimmune diseases suggests a potential therapy
11. The Japanese traditional therapy, honokiol, blocks key protein in inflammatory brain damage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... are disappearing, and though conservationists are examining several possible ... rain and light pollution, a key piece of the ... once they leave their breeding sites, and what threats ... answer this question, a team of researchers out of ... map produced for a songbird, using tracking from both ...
(Date:7/23/2014)... 780 million people around the world have no access ... Organization (WHO), 3.4 million people die from water-related diseases ... goal of making a contribution to solving this problem. ... Stark, head of the Functional Materials Laboratory, the 23-year-old ... a prototype. , "What makes our DrinkPure filter unique ...
(Date:7/23/2014)... This news release is available in German . ... shape and stability to cells, drive metabolic processes and ... into complex three-dimensional shapes. Scientists at the Max Planck ... that proteins can be constructed of similar amino acid ... suggests that the proteins that exist today arose from ...
Breaking Biology News(10 mins):York University researchers use bird 'backpacks' to put wood thrushes migration on the map 2ETH student develops filter for clean water around the world 2Protein evolution follows a modular principle 2
... of our hearts and blood vessels. Conventional treatment attempts ... in the blood plasma. The opposite approach, which involves ... acid, has proven unpopular among patients up to now. ... acid has an unpleasant but harmless side-effect: the ...
... November, the Malaspina expedition 2010 will set sail from ... the Spanish National Research Council (CSIC) aims to evaluate ... to survey their biodiversity. The expedition has the backing ... and takes its name from mariner Alessandro Malaspina, the ...
... MADISON, WI, July 26th, 2010 NASA scientists ... and ground-based observations of precipitation. The NASA data ... to monitor non-point pollution and improve water quality. ... of Science Systems and Applications, Inc., incorporated two ...
Cached Biology News:Preventing heart problems while keeping a cool head 2Preventing heart problems while keeping a cool head 3Malaspina expedition 2010 2NASA satellite improves pollution monitoring 2
(Date:7/23/2014)... Sergei Filippov (MIPT and Russian Quantum Center at ... Czech Republic, and the Institute of Physics in ... quantum entanglement of particles passing through an amplifier ... distances. Details are provided in an article published ... (see preprint). , Quantum entangled particles are considered ...
(Date:7/23/2014)... Last year, Formedix celebrated its partnership with ... data management solutions for clinical trials. The company launched ... data capture (EDC) and clinical data management. Formedix, a ... added TrialMaster to its Transform for EDC product line. ... TrialMaster, is being released this week, in response to ...
(Date:7/23/2014)... DuPont Pioneer announced today that Neal Gutterson, ... Agricultural Biotechnology (ABT), effective July 21, 2014. Gutterson joins ... as president, chief executive officer and board member. , ... seed and crop protection industry to this integral role ... president of DuPont Pioneer. “I am looking forward to ...
(Date:7/23/2014)... 2014  Sofinnova Ventures, a Menlo Park ... of Sofinnova Venture Partners IX, L.P. at the hard ... initial fund target of $425 million. Sofinnova ... Consistent with recent funds, SVP IX will provide capital ... along with select investments in earlier stage opportunities. Investments ...
Breaking Biology Technology:Scientists find way to maintain quantum entanglement in amplified signals 2Scientists find way to maintain quantum entanglement in amplified signals 3Scientists find way to maintain quantum entanglement in amplified signals 4Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 3DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 2DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 3Sofinnova Raises $500 Million Biotech Venture Fund 2
... executives, mostly in denial, are shunning the subject. Smart ones ... general broadcasts. This is a revolution, and the entire model ... , Device Explosion , ,The receptacles to receive the ... but rather handheld devices or the hundreds of gadgets and ...
... Read Part 1 . Winslow Sargeants combination of ... the world of entrepreneurship and risk. His memories of growing ... tenacity is essential. , , Winslow Sargeant ... a child. In June, 1974, U.S. District Court Judge W. ...
... MadCity Murder Mystery game Madison, Wis. ... the UW-Madison School of Education, hopes to bring a ... games, which combine aspects of physical activity, traditional reading ... through the UW System and the Academic ADL ...
Cached Biology Technology:When TV surrenders to Web... 2When TV surrenders to Web... 3Winslow Sargeant: Stepping onto the train called Wisconsin - Part 2 2Winslow Sargeant: Stepping onto the train called Wisconsin - Part 2 3Winslow Sargeant: Stepping onto the train called Wisconsin - Part 2 4Augmented reality brings a new dimension to learning 2Augmented reality brings a new dimension to learning 3
... greater incorporation of Br-dUTP results in a ... using a fluorescein-labeled anti-BrdU antibody. Propidium ... kit to counterstain the total DNA. Features ... in improved detection than found by using ...
... cytoplasmic expression of an N-terminal FLAG® fusion ... selection marker from bicistronic mRNA. Two ... MCS2 for transcription of a single message ... useful for protein-protein interaction studies, multi-subunit proteins, ...
...
Mouse monoclonal antibody raised against a partial recombinant SCARB2. NCBI Entrez Gene ID = SCARB2...
Biology Products: