Navigation Links
New scientific method unmasks chronic infections
Date:8/8/2012

Chronic infections are a large and growing problem throughout the developed world, and intensive research is being conducted in ways to combat the recalcitrant bacteria. When bacteria aggregate into so-called biofilm, they become resistant to antibiotics. Until now scientists have only been able to speculate about what happens when bacteria overpower the immune system during a chronic infection.

In close collaboration between various specialist fields, Danish scientists have now developed a method that gives a precise picture of how the immune system works. Using 5 mm silicone tubes, scientists created a model system that allows them to look closely at how the immune system and bacteria interact in isolation:

"Although we have always suspected that to cause a chronic infection, bacteria knock out the immune system's white blood cells, the new method allows us to see precisely what happens. Instead of looking down on the bacterial surface, we can examine a section to see the interaction directly and follow how the bacteria react to white blood cells and to antibiotics. That enables us to understand the basic processes behind chronic infections," explains Associate Professor Thomas Bjarnsholt, University of Copenhagen.

PhD student Maria Alhede adds: "The new method allows us to investigate which compounds the bacteria are secreting while overpowering the white blood cells. Conversely, we can also see what happens when the immune system works. The white blood cells make DNA traps that capture the bacteria, but that used to be only a guess," relates Maria Alhede, Department for International Health, Immunology and Microbiology.

Scientists follow the effect of drugs in the organism

The Core Facility for Integrated Microscopy at the Department of Biomedical Sciences has some of Europe's most sophisticated microscopes for conducting health research. By combining light microscopy and electron microscopy, scientists
'/>"/>

Contact: Associate Professor Ph.D. Thomas Bjarnsholt
tbjarnsholt@sund.ku.dk
45-20-65-98-88
University of Copenhagen
Source:Eurekalert

Page: 1 2

Related biology news :

1. Tale of 2 scientific fields -- ecology and phylogenetics -- offers new views of Earths biodiversity
2. Inaugural cross-disciplinary Public Participation in Scientific Research conference
3. FirstMark Scientific Board of Advisors Meet to Discuss New Clinical Studies for PREvent
4. New model in scientific publishing: GigaScience combines article and data publication
5. WALTHAM® demonstrates commitment to scientific dialogue and exchange at international human animal interaction conference
6. CRN assesses current state of scientific research for nutritional supplements
7. Scientific meeting at Virginia Tech will make more than $2 million economic impact
8. NTU researchers study little mighty creature for scientific breakthrough
9. FirstMark Welcomes Renowned Cardiologist and Researcher Dr. Prediman K. Shah to Scientific Advisory Board
10. FirstMark Welcomes Renowned Cardiologist and Researcher Dr. Prediman K. Shah to Scientific Advisor Board
11. Womens scientific achievements often overlooked and undervalued
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... ALBUQUERQUE, N.M. A credit-card-sized anthrax detection cartridge developed ... small business makes testing safer, easier, faster and cheaper. ... causes anthrax, is commonly found in soils all over ... illness in both humans and animals. The bacteria can ... to B. anthracis may occur through skin ...
(Date:4/17/2014)... A Kansas State University engineer has developed a ... detects improvised explosive devices. The same technique could ... the Steven M. and Kay L. Theede chair ... nuclear engineering, and his research team have created ... or in car trunks. The distance detection method ...
(Date:4/17/2014)... Clemson professor Rajendra Singh Thursday as a "Champion ... expand solar deployment in the residential, commercial and ... Professor of Electrical and Computer Engineering and director ... a local hero leading the charge across the ... solar power and driving policy changes at the ...
Breaking Biology News(10 mins):Pocket-sized anthrax detector aids global agriculture 2Pocket-sized anthrax detector aids global agriculture 3Patented research remotely detects nitrogen-rich explosives 2White House honors Clemson professor as 'Champion of Change' for solar deployment 2
... at the recent United Nations meeting emphasized nutrition as ... of State Hillary Clinton said a key focus is ... of Missouri nutrition experts say getting back to basics ... families and communities in many ways. As ...
... to be met is a significant increase in the use ... to grow in the future, because biomass is used in ... and various types of materials. The planning of biomass usage ... gap between what is included in countries, and regions, current ...
... Clemson University researchers recently reported finding a new class ... how cells repair damaged DNA. The finding from Cao,s ... with computational chemist Brian Dominy appeared in the Sept. ... "A new family of deamination repair enzymes in ...
Cached Biology News:Eating balanced meals, farm-fresh produce benefits families, communities, nutrition researchers say 2Better planning required if EU is to meet energy targets 2Clemson University biochemists identify new genetic code repair tool 2
(Date:1/15/2014)... January 15, 2014 A study has been ... the Formula 1 track could help to tackle the problem ... (MAT), Stowhealth (a GP surgery based in Stowmarket) and academics ... Simplyhealth. Telemetry technology, which is inspired by equipment ...
(Date:1/15/2014)... Rochester, NY (PRWEB) January 15, 2014 The ... cause a major disease. One of these latent viruses is ... is rheumatoid arthritis (RA). Rheumatoid arthritis (RA) is a chronic ... the theory, a study found that RA patients have high ...
(Date:1/15/2014)... Freeslate, Inc ., the leading ... Lupin Limited, one of India’s top five pharmaceutical companies, ... System for high throughput solid form screening. ... a wide range of quality, affordable generic and branded ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Date: Friday, April ... Location: Warrington Country Club, 1360 Almshouse Road, Warrington, Pa. ... nonprofit organization solely dedicated to finding a cure for hepatitis ... worldwide, will host its annual Crystal Ball on Friday, April ...
Breaking Biology Technology:Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2
... and OSAKA, Japan, May 18, 2011 Cellectis ... genome customization specialist, has appointed Wako Pure Chemical ... Company,s broad portfolio of research products and services, ... Chemical Industries is a leading distributor of research ...
... SAN JOSE, Calif., May 18, 2011 Oclaro, Inc. ... optical communications and laser solutions, today announced that its ... by Pantec Biosolutions, the leading provider of epidermal medical ... Laser Epidermal System) platform. This cutting-edge new laser platform ...
... May 17, 2011 New data presented today ... moderate to severe chronic prostatitis/chronic pelvic pain syndrome ... meeting of the American Urological Association, RAPAFLO(R) also ... of life. Chronic prostatitis/chronic pelvic pain ...
Cached Biology Technology:Cellectis bioresearch Appoints Wako as Exclusive Distributor of its Genome Customization Solutions in Japan 2Pantec Biosolutions Selects Oclaro Laser Diode Bars for Transdermal Drug Delivery and Tissue Ablation Systems 2Pantec Biosolutions Selects Oclaro Laser Diode Bars for Transdermal Drug Delivery and Tissue Ablation Systems 3Pantec Biosolutions Selects Oclaro Laser Diode Bars for Transdermal Drug Delivery and Tissue Ablation Systems 4Watson Pharmaceuticals Announces New Research Showing RAPAFLO(R) (silodosin) Improves Outcomes for Chronic Prostatitis/Chronic Pelvic Pain Syndrome 2Watson Pharmaceuticals Announces New Research Showing RAPAFLO(R) (silodosin) Improves Outcomes for Chronic Prostatitis/Chronic Pelvic Pain Syndrome 3Watson Pharmaceuticals Announces New Research Showing RAPAFLO(R) (silodosin) Improves Outcomes for Chronic Prostatitis/Chronic Pelvic Pain Syndrome 4Watson Pharmaceuticals Announces New Research Showing RAPAFLO(R) (silodosin) Improves Outcomes for Chronic Prostatitis/Chronic Pelvic Pain Syndrome 5Watson Pharmaceuticals Announces New Research Showing RAPAFLO(R) (silodosin) Improves Outcomes for Chronic Prostatitis/Chronic Pelvic Pain Syndrome 6
Component of HyperMu™ Insertion Kit...
Request Info...
... x 2 , Maintenance ... /each , Immunizations/Boost injections x5 ... ml) x1 /each , Production bleed ... Final Bleed ~ 100 ml blood (~50 ml ...
... 500 g protein in ... mouse whole cell lysate; Abelson transformed macrophage ... as Western blotting positive control, ... and thawing should be minimized, ...
Biology Products: