Navigation Links
New pump created for microneedle drug-delivery patch
Date:9/1/2010

WEST LAFAYETTE, Ind. - Purdue University researchers have developed a new type of pump for drug-delivery patches that might use arrays of "microneedles" to deliver a wider range of medications than now possible with conventional patches.

The current "transdermal" patches are limited to delivering drugs that, like nicotine, are made of small hydrophobic molecules that can be absorbed through the skin, said Babak Ziaie, a professor of electrical and computer engineering and biomedical engineering.

"There are only a handful of drugs that currently can be administered with patches," he said. "Most new drugs are large molecules that won't go through the skin. And a lot of drugs, such as those for treating cancer and autoimmune disorders, you can't take orally because they aren't absorbed into the blood system through the digestive tract."

Patches that used arrays of tiny microneedles could deliver a multitude of drugs, and the needles do not cause pain because they barely penetrate the skin, he said.

"It's like a bandage - you would use it and discard," Ziaie said.

The patches require a pump to push the drugs through the narrow needles, which have a diameter of about 20 microns, or roughly one-fourth as wide as a human hair. However, pumps on the market are too complex for patches, he said.

"We have developed a simple pump that's activated by touch from the heat of your finger and requires no battery," Ziaie said.

The pump contains a liquid that boils at body temperature so that the heat from a finger's touch causes it to rapidly turn to a vapor, exerting enough pressure to force drugs through the microneedles.

"It takes 20 to 30 seconds," Ziaie said.

The liquid is contained in a pouch separated from the drug by a thin membrane made of a rubberlike polymer, called polydimethylsiloxane, which is used as diaphragms in pumps.

Research findings are detailed in a paper being pre
'/>"/>

Contact: Emil Venere
venere@purdue.edu
765-494-4709
Purdue University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. A lab rat -- created in the lab
2. Smart orthopedic implants and self-fitting tissue scaffolding created by UMMS researchers
3. Alzheimers rat created for human research
4. New period of brain plasticity created with transplanted embryonic cells
5. MSU scientists unlock key enzyme using newly created cool method
6. 3-D kidney atlas created for researchers and physicians
7. Most extensive genetic resource for reef-building coral created
8. Microneedle, quantum dot study opens door to new clinical cancer tools
9. Ocean stirring and plankton patchiness
10. Even small patches of urban woods are valuable for migrating birds
11. Ancient artifacts reveals as northern ice patches melt
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New pump created for microneedle drug-delivery patch
(Date:10/16/2014)... NXT-ID, Inc. (NASDAQ: NXTD ... company focused on the growing mobile commerce market announces ... the Smart Wallet, at the 13 th annual ... global conference on the intersection of technology and the ... , founder and publisher of the Strategic News Service™, ...
(Date:10/15/2014)... spreading rapidly and to an unexpected extent. The outbreak ... and the virus shows a new disease dynamic in ... this reason, the German National Academy of Sciences Leopoldina, ... and the Union of the German Academies of Sciences ... epidemic today. , In the statement the academies call ...
(Date:10/14/2014)... thieves, prostate cancer tumors scavenge and hoard copper that ... avarice may be a fatal weakness. , Researchers ... prostate cancer cells by delivering a trove of copper ... cells brimming with the mineral, leaving non-cancer cells healthy. ... commercially available for other uses, could soon be tested ...
Breaking Biology News(10 mins):NXT-ID Inc. to Present at 13th Annual FiRe Conference 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 3Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5Prostate cancer's penchant for copper may be a fatal flaw 2
... , April 27 Tyco International Ltd. (NYSE: ... of its Electrical & Metal Products business. Tyco expects to file documents ... months and to complete the proposed transaction in the first half of ... traded U.S. company. , , ...
... , April 27 The Breema Center today ... Germany the 12-16 of May, 2010. Breema is a ... emphasizes the mind-body connection.  The Intensive program is designed to ... long time students deepen their understanding of Breema and its ...
... Debt advice specialists at MoneySolve believe that the record level of personal ... of financial management and debt education. , ... More than 134,000 people became insolvent during 2009, by entering ... to experience severe financial difficulties. Experts at MoneySolve believe that by increasing ...
Cached Biology News:Tyco International To Pursue Spin-Off of Electrical & Metal Products Business 2Tyco International To Pursue Spin-Off of Electrical & Metal Products Business 3Breema Center to Host International Intensive Week in Buhl, Germany 2Breema Center to Host International Intensive Week in Buhl, Germany 3
(Date:10/22/2014)... , Oct. 22, 2014 /PRNewswire/ - iCo Therapeutics ("iCo" ... announced next steps for its Oral Amphotericin B ... its in vitro work involving samples ... now plans to complete pre clinical studies and ... Phase 1A clinical trial, utilizing approximately $700,000 of ...
(Date:10/22/2014)... -- Research and Markets  has announced the addition ... Application, Geography - Global Analysis and Forecast (2014 - ... Organic electronics, also called as polymer electronics or plastic ... with small conductive molecules and electrically conductive polymers. It ... are carbon based, made using synthetic strategies developed in ...
(Date:10/20/2014)... 20, 2014 The report “Pharmacy ... Systems, Packaging and Labeling Systems, Table-top Counters) by ... Global Forecasts & Trends to 2019” analyzes and ... in North America, Europe, Asia-Pacific, and the Rest ... tables and 30 figures spread through 300 pages ...
(Date:10/20/2014)... October 20, 2014 Convey Computer ... a team from Iowa State University won first place ... Using a Convey HC-2ex, the team’s solution achieved the ... faster than the second place finisher. , Experts from ... upon the month long challenge, using a variety of ...
Breaking Biology Technology:iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 2iCo Therapeutics Announces Advancement of Oral Amphotericin B Program 3Global Organic Electronics (Semiconductor, Conductive, Dielectric and Substrate) Market - Analysis and Forecast (2014 - 2020) 2Global Organic Electronics (Semiconductor, Conductive, Dielectric and Substrate) Market - Analysis and Forecast (2014 - 2020) 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 2Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 4Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 3
... funded by the Biotechnology and Biological Sciences Research Council (BBSRC), ... new type of vaccine to protect chickens against coccidiosis, the ... of this type -- based on proteins from the coccidiosis ... could be produced on a larger scale than is currently ...
... of researchers has invented new artificial muscles strong enough to ... the same flexibility of an elephant,s trunk or octopus limbs. ... Express, the scientists and engineers from the University of ... of Texas at Dallas and Hanyang University in Korea detail ...
... MANSFIELD, Mass., Oct. 13, 2011 PrimeraDx today announced ... President of Corporate Development.   "Jeff,s diverse ... a great addition to the leadership team," Said Matt ... leverage the multimodal capabilities of the ICE Plex ...
Cached Biology Technology:A step towards new vaccines for most important chicken parasite 2A step towards new vaccines for most important chicken parasite 3UBC researchers invent tiny artificial muscles with the strength, flexibility of elephant trunk 2PrimeraDx Appoints Jeff Liter as VP of Corporate Development 2
... Note: Protein determined by Biuret Physical form: ... Tris-HCl, pH 7.6, 1 mM MgCl 2 ... Preparation Unit Definition: One unit will hydrolyze ... at pH 9.8 at 37 C. • ...
... Varioskan is a high performance ... dispenser and incubator. With the advanced ... and reliability for drug discovery assay ... for fluorescence intensity, time-resolved fluorescence and ...
Immulon 2 HB 1x8 Strip assembled, C-bottom; high binding irradiated surface to provide increased binding affinity for hydrophilic proteins and complexes....
... RCT series of refrigerated cold traps offers ... of low volatility/aqueous solvents or high volatility ... other vacuum concentrators/centrifugal evaporators. Also used for ... such as used in electron microscopes. Can ...
Biology Products: