Navigation Links
New method for uncovering side effects before a drug hits the market
Date:1/2/2013

Side effects are a major reason that drugs are taken off the market and a major reason why patients stop taking their medications, but scientists are now reporting the development of a new way to predict those adverse reactions ahead of time. The report on the method, which could save patients from severe side effects and save drug companies time and money, appears in ACS' Journal of Chemical Information and Modeling.

Yoshihiro Yamanishi and colleagues explain that drug side effects are a major health problem the fourth-leading cause of death in the U.S. which by some estimates claim 100,000 lives every year. Serious side effects are the main reason why existing drugs must be removed from the market and why pharmaceutical companies halt development of new drugs after investing millions of dollars. Current methods of testing for side effects are costly and inaccurate. That's why the scientists sought to develop a new computer-based approach to predicting possible side effects.

They show the usefulness of their proposed method on simultaneous prediction of 969 side effects of 658 drugs that already are in wide medical use. The method is based on knowledge about chemical and biological information about ingredients in these medications. They also used the approach to identify possible side effects for many uncharacterized molecules. Based on that work, the scientists conclude that the new method could be helpful in uncovering serious side effects early in the development and testing of new drugs, avoiding costly investment in medications unsuitable for marketing.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers develop tool to evaluate genome sequencing method
2. Improving the development of new cancer models using an advanced biomedical imaging method
3. Scientists develop novel method to study parasite numbers in wild seabirds
4. New method for creating long-lived stem cells used for bone replacement
5. Salk scientists develop faster, safer method for producing stem cells
6. New method for diagnosing malaria
7. Scientists from Bangalore and Mainz develop new methods for cooling of ions
8. Scientists discover new method of gene identification
9. A new computational method for timing the tree of life
10. Texas Biomed reports faster, more economical method for detecting bioterror threats
11. Temporary storage for electrons: Natural method of producing hydrogen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/16/2016)... -- Research and Markets has announced the addition of ... 2021" report to their offering. ... The biometric vehicle access system market, in ... 14.06% from 2016 to 2021. The market is estimated to be ... Million by 2021. The growth of the biometric vehicle access system ...
(Date:12/15/2016)... , Dec 15, 2016 ... Research and Markets has announced the addition ... offering. The report forecasts the global military biometrics market ... The report has been prepared based on an in-depth market ... and its growth prospects over the coming years. The report also includes ...
(Date:12/12/2016)... -- Researchers at Trinity College, Dublin, are opening up ... material with Silly Putty. The mixture (known as "G-putty") ... sense pulse, blood pressure, respiration, and even the ... The research team,s findings were published Thursday in ... Due ...
Breaking Biology News(10 mins):
(Date:1/17/2017)... Jan. 17, 2017   Pulmatrix, Inc . (NASDAQ: ... developing innovative inhaled therapies to address serious pulmonary diseases, ... infections in the lungs of CF patients, PUR1900, has ... by the U.S. Food & Drug Administration. ... to speed the development of novel drugs against important ...
(Date:1/17/2017)...  Only nine percent of U.S. consumers believe pharmaceutical ... 16 percent believe health insurance companies do, according to ... of U.S. adults believe health care providers (such as ... hospitals (23%). "We are in the midst ... , vice president of reputation management and public affairs ...
(Date:1/17/2017)... (PRWEB) , ... January 17, 2017 , ... Pono ... balanced, peaceful and healthy lifestyle, announced today the official launch of its much-anticipated Pono ... the mind. , In development for over a year, the patented Pono ...
(Date:1/17/2017)... ... January 17, 2017 , ... Diagenode, ... recently announced a collaboration with the Heidelberg University Hospital and the German Cancer ... preparation, following the company’s successful launch of its CATS (Capture and Amplification ...
Breaking Biology Technology: