Navigation Links
New method for uncovering side effects before a drug hits the market
Date:1/2/2013

Side effects are a major reason that drugs are taken off the market and a major reason why patients stop taking their medications, but scientists are now reporting the development of a new way to predict those adverse reactions ahead of time. The report on the method, which could save patients from severe side effects and save drug companies time and money, appears in ACS' Journal of Chemical Information and Modeling.

Yoshihiro Yamanishi and colleagues explain that drug side effects are a major health problem the fourth-leading cause of death in the U.S. which by some estimates claim 100,000 lives every year. Serious side effects are the main reason why existing drugs must be removed from the market and why pharmaceutical companies halt development of new drugs after investing millions of dollars. Current methods of testing for side effects are costly and inaccurate. That's why the scientists sought to develop a new computer-based approach to predicting possible side effects.

They show the usefulness of their proposed method on simultaneous prediction of 969 side effects of 658 drugs that already are in wide medical use. The method is based on knowledge about chemical and biological information about ingredients in these medications. They also used the approach to identify possible side effects for many uncharacterized molecules. Based on that work, the scientists conclude that the new method could be helpful in uncovering serious side effects early in the development and testing of new drugs, avoiding costly investment in medications unsuitable for marketing.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Researchers develop tool to evaluate genome sequencing method
2. Improving the development of new cancer models using an advanced biomedical imaging method
3. Scientists develop novel method to study parasite numbers in wild seabirds
4. New method for creating long-lived stem cells used for bone replacement
5. Salk scientists develop faster, safer method for producing stem cells
6. New method for diagnosing malaria
7. Scientists from Bangalore and Mainz develop new methods for cooling of ions
8. Scientists discover new method of gene identification
9. A new computational method for timing the tree of life
10. Texas Biomed reports faster, more economical method for detecting bioterror threats
11. Temporary storage for electrons: Natural method of producing hydrogen
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... Research and Markets has announced the addition of the "Global ... ... at a CAGR of 30.37% during the period 2017-2021. ... based on an in-depth market analysis with inputs from industry experts. ... the coming years. The report also includes a discussion of the ...
(Date:4/11/2017)... NXT-ID, Inc. (NASDAQ:   NXTD ) ... appointment of independent Directors Mr. Robin D. Richards ... Directors, furthering the company,s corporate governance and expertise. ... Gino Pereira , Chief Executive ... their guidance and benefiting from their considerable expertise as we ...
(Date:4/5/2017)... 5, 2017  The Allen Institute for Cell Science ... a one-of-a-kind portal and dynamic digital window into the ... the first application of deep learning to create predictive ... lines and a growing suite of powerful tools. The ... and future publicly available resources created and shared by ...
Breaking Biology News(10 mins):
(Date:8/11/2017)... (PRWEB) , ... August 11, 2017 , ... ... food production, and, in particular, more natural alternatives to synthetic ingredients,” said Matt ... of Third Wave, with the established manufacturing presence and know-how of Biorigin will ...
(Date:8/10/2017)... ... August 09, 2017 , ... Teachers from ... students. From August 14th through the 16th, the University City Science Center will ... summer of 2016, provides Philadelphia-based middle school educators an opportunity for professional development ...
(Date:8/10/2017)... ... 09, 2017 , ... Each year in the United States more than 300,000 ... an independent lifestyle and, even worse, the one-year mortality rate is high, ranging from ... University of California Davis Medical Center (Sacramento) and Second Xiangya Hospital of the Central-South ...
(Date:8/10/2017)... California, USA (PRWEB) , ... August 09, 2017 ... ... has partnered with four international biomedical optics laboratories — the Wellman Center for ... Hospital, Medical Laser Center Lübeck and the Beckman Laser Institute at University of ...
Breaking Biology Technology: