Navigation Links
New magnetic separation technique might detect multiple pathogens at once
Date:10/29/2007

DURHAM, N.C. -- A magnetic separation technique developed by researchers at Duke University's Pratt School of Engineering and Purdue University makes it relatively simple to sort through beads hundreds of times smaller than the period at the end of this sentence.

The method could lead to new technologies for medical or environmental testing, according to the researchers. For example, specially coated magnetic particles designed to attract particular viruses or bacteria might be used in tailored combinations to simultaneously test for multiple infectious pathogens in a blood or water sample.

Benjamin Yellen, assistant professor of mechanical engineering and materials science at Duke, and Gil Lee, associate professor of chemical engineering at Purdue, report their findings in the December issue of the journal Lab on a Chip (see http://tinyurl.com/3aayh8).

"If there were five viruses that a patient might have been exposed to, you could potentially develop a technique to look for those five viruses all at the same time," Yellen said. In principle, such a test could be done with just a single drop of blood, as long as there was virus in the sample.

As an initial demonstration of the concept, the researchers attached two "model pathogens," a baker's yeast and a soil bacterium, to magnetic beads, and used their technique to selectively isolate them.

The magnetic separation method, which the researchers call magnetophoresis, uses a rotating magnetic field and a microchip containing an array of miniature magnets to separate tiny magnetic beads based on their size within a matter of minutes.

The physics behind the technique is as interesting as its potential applications, Yellen added. "The method causes certain particles to become essentially immobile -- just jittering back and forth -- while others move off the chip where they can be isolated. It implies that we could ac
'/>"/>

Contact: Kendall Morgan
kendall.morgan@duke.edu
919-660-8414
Duke University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Overbearing colored light may reveal a second mechanism by which birds interpret magnetic signals
2. Bacteria which sense the Earths magnetic field
3. Magnetic probe successfully tracks implanted cells in cancer patients
4. Magnetic system could be key to surgery without scars
5. Magnetic computer sensors may help study biomolecules
6. Rensselaer researchers develop approach that predicts protein separation behavior
7. Researchers to develop active nanoscale surfaces for biological separations
8. Einsteins tea leaves inspire new blood separation technique
9. New Technique for Tracking Gene Regulators
10. Live Recombinant Adenovirus Vaccine Technique Explored
11. New lab technique identifies high levels of pathogens in therapy pool
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/14/2014)... Ohio (Oct. 14, 2014)—It,s been millions of years since ... a team led by Ohio University scientists is breathing ... model airflow through dinosaur snouts. The research has important ... only breathe but to enhance the sense of smell ... ,nosy, animals," said Ohio University doctoral student Jason Bourke, ...
(Date:10/14/2014)... kind of stem cell that can become either a liver ... to a study published today in the journal Stem ... contradicts current theory on how organs arise from cell layers ... and future treatment for, liver cancer., Thanks to stem cells, ... made up of more than 200 cell types. The original, ...
(Date:10/14/2014)... team of scientists led by researchers at the ... University of Miami Miller School of Medicine (UMMSM) ... pathway underlying bipolar (manic depressive) disorder, a breakthrough ... bipolar affective disorder, as well as depression and ... published online this week in Nature Molecular ...
Breaking Biology News(10 mins):Dinosaur breathing study shows that noses enhanced smelling and cooled brain 2Dinosaur breathing study shows that noses enhanced smelling and cooled brain 3Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 2Stem cell discovery challenges dogma on how fetus develops; holds insights for liver cancer and reg 3Rare genetic disease protects against bipolar disorder 2Rare genetic disease protects against bipolar disorder 3
... known PSA blood test for prostate cancer in men may ... breast cancer, the most common form of cancer in women ... ACS journal Analytical Chemistry . Chien Chou and ... test also is a potential biomarker of breast cancer in ...
... is available in German and Spanish . ... Chile pose a higher threat to its neighbour, Argentina, than ... of Concepcin in Chile and the Helmholtz Centre for Environmental ... particular, 22 non-native species which occur in Chile on connecting ...
... has shown that light is the key to getting our ... exploring the resynchronisation mechanism in insects has discovered a molecule ... University of London looked at the impact of light on ... flies. They identified a novel molecule, QUASIMODO (QSM), which was ...
Cached Biology News:Chile is more dangerous for Argentina than vice versa 2Chile is more dangerous for Argentina than vice versa 3Newly discovered molecule essential to resetting 'body clocks' 2
(Date:10/22/2014)... 2014 Involution Studios , a ... a new infographic, Understanding Ebola . The ... designed, easy to follow informative tool for anyone wanting ... symptoms and prevention. , "As the news has spread ... Ebola outbreak represents not only a healthcare crisis with ...
(Date:10/22/2014)... SC (PRWEB) October 22, 2014 ... of its cardiovascular pharmacogenetics menu, which enables healthcare ... outcomes. With PCLS’s evidence-based results, healthcare providers ... and optimize their therapy, while minimizing risks for ... the U.S., according to the FDA [1] more ...
(Date:10/22/2014)... Nuvilex, Inc. (OTCQB: NVLX) – According to ... are living with diabetes, with  that number expected to ... market for diabetes treatments is approximately $500 billion.  ... from pancreatic cancer.  Pancreatic cancer is the fourth most ... the United States , and according to ...
(Date:10/20/2014)... , Oct. 20, 2014 Mapp ... experimental ZMapp™ antibody therapeutic to fight the Ebola ... difficult and time-consuming the production of pharmaceuticals can ... research publisher said that while some may be ... this compound, those with industry knowledge are well ...
Breaking Biology Technology:Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2PCLS Announces Expansion of Cardiovascular Pharmacogenetic Testing Menu 2PCLS Announces Expansion of Cardiovascular Pharmacogenetic Testing Menu 3Nuvilex Brief Analyst Report: Thinking Outside the Box by BrokerBank Securities, Inc. 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3
... The Wisconsin Alumni Research Foundation ( WARF ) and ... nutritional supplement manufacturer today with willful and deliberate patent ... , ,The French company, Arkopharma , and its ... the suit when they continued to sell certain products ...
... - The growing body of university research under development beyond ... grow at an even faster pace as the result of ... System presidents and the Wisconsin Alumni Research Foundation. ... for researchers at UW System schools. The focus, however, extends ...
... Lee Dreyfus made a few waves when he suggested ... blue-eyed Arabs of the Upper Midwest" by selling fresh ... many of his ideas, often delivered off-the-cuff to mask ... Dreyfus proposal simultaneously stirred the imagination and set off ...
Cached Biology Technology:WARF sues French company over patent violation 2WiSys to distribute $1 million in research funds 2WiSys to distribute $1 million in research funds 3WiSys to distribute $1 million in research funds 4Fresh water could be a deep economic wellspring for Wisconsin 2Fresh water could be a deep economic wellspring for Wisconsin 3