Navigation Links
New lung cancer study takes page from Google's playbook
Date:3/25/2013

SAN DIEGO - The same sort of mathematical model used to predict which websites people are most apt to visit is now showing promise in helping map how lung cancer spreads in the human body, according to a new study published in the journal Cancer Research.

A team of researchers used an algorithm similar to the Google PageRank and to the Viterbi Algorithm for digital communication to analyze the spread patterns of lung cancer. The team includes experts from the University of Southern California (USC), Scripps Clinic, The Scripps Research Institute, University of California, San Diego Moores Cancer Center and Memorial Sloan-Kettering in New York.

"This research demonstrates how similar the Internet is to a living organism," said USC Viterbi School of Engineering Professor Paul Newton, Ph.D., the lead and corresponding author of the study. "The same types of tools that help us understand the spread of information through the web can help us understand the spread of cancer through the human body."

Employing a sophisticated system of mathematical equations known as a Markov chain model, the research team guided by USC applied mathematicians found that metastatic lung cancer does not progress in a single direction from primary tumor site to distant locations, which has been the traditional medical view. Instead, they found that cancer cell movement around the body likely occurs in more than one direction at a time.

Researchers also learned that the first site to which the cells spread plays a key role in the progression of the disease. The study showed that some parts of the body serve as "sponges" that are relatively unlikely to further spread lung cancer cells to other areas of the body. The study identified other areas as "spreaders" for lung cancer cells.

The study revealed that for lung cancer, the main spreaders are the adrenal gland and kidney, whereas the main sponges are the regional lymph nodes, liver and
'/>"/>

Contact: Robert Perkins
perkinsr@usc.edu
213-740-9226
University of Southern California
Source:Eurekalert

Page: 1 2

Related biology news :

1. Tortoise and the hare: New drug stops rushing cancer cells, slow and steady healthy cells unharmed
2. Embryonic development protein active in cancer growth
3. BRG1 mutations confer resistance to hormones in lung cancer
4. Genetic variation in East Asians found to explain resistance to cancer drugs
5. Beyond the microscope: Identifying specific cancers using molecular analysis
6. Marshall University study may lead to new treatments for prostate cancer
7. Salk scientists open new window into how cancers override cellular growth controls
8. Penn research points to new way of preserving fertility for boys undergoing cancer treatment
9. Genetic abnormality offers diagnostic hope for childrens cancer
10. Protein jailbreak helps breast cancer cells live
11. Breast cancer risk gene discovery fast tracked by new technology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2015)... , Jan. 30, 2015  It is gratifying ... power and potential for genomic science as a means ... disease prevention and treatment.  I was honored to participate ... government-funded precision medicine program. Since the ... science of genomics—from the first sequenced genome of a ...
(Date:1/22/2015)... 13, 2015  Today, FreeWavz ( www.FreeWavz.com ), the ... campaign on Fundable, https://www.fundable.com/freewavz . FreeWavz will ... capacity to meet customer demand. Logo ... http://photos.prnewswire.com/prnh/20150113/168790 Invented by Dr. ...
(Date:1/22/2015)... POINT ROBERTS, Washington , January 20, 2015 ... technology and tech stocks, releases video from the CES 2015 ... security consultant Apollo Robbins . Apollo shows ... Wocket™ biometric smart wallet, a product of NXT-ID, Inc. (NASDAQ: ...
Breaking Biology News(10 mins):J. Craig Venter, Ph.D., Co-Founder and CEO, Human Longevity, Inc. (HLI) Participates in White House Precision Medicine Event 2FreeWavz Launches on Fundable to Drive Speed-to-Market in 2015 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3
... San Diego have received New Innovator Awards from the ... translation of cutting-edge science and research to improvements in ... of bioengineering at the UC San Diego Jacobs School ... of medicine at UC San Diego,s School of Medicine, ...
... in German . Scientists at the ... colleagues, have decoded the genome of the Pristionchus pacificus ... In their work, which has been published in the ... from Professor Ralf J. Sommer,s department in Tbingen have ...
... professor at the UC San Diego Jacobs School of Engineering, ... With a new $1.5 million New Innovator Award grant from ... to do just that. , The awards, announced Sept. ... of new investigators who have exceptional creativity and propose bold ...
Cached Biology News:NIH doles out $3M in new innovator awards to 2 UC San Diego faculty 2Insight into the evolution of parasitism 2Insight into the evolution of parasitism 3Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering 2Generation innovation: Young UC San Diego bioengineer to use NIH grant to fuel tissue engineering 3
(Date:3/2/2015)... 2015 VLP Therapeutics, LLC. ("VLP"), a ... on the research and development of therapeutic and ... upon a novel and proprietary vaccine technology, today ... Grant Award from the Montgomery County Department of ... is awarded to life sciences companies in ...
(Date:3/2/2015)... , March 2, 2015 ... and healthy whole food nutrition products reveal technological ... lifestyle related disorders such as hyperglycemia, obesity, insulin ... concerns.  Nutraceutical and Biotech Companies in focus today ... Nature Foods Ltd. (NYSE: ANFI ), ...
(Date:3/2/2015)... SANTA BARBARA, Calif. , March 2, 2015 ... a biotechnology company developing therapies for autoimmune and ... Trademark Office (USPTO) has issued an important new ... immune system function through the targeting of CLIP. ... the targeted peptide technology underlying VG Life Sciences, ...
(Date:3/2/2015)... Outside GC, the leading provider of on-demand, ... Debbie Casey as a member of the firm, further ... , Debbie has spent over 20 years in ... Care North America in both legal and business capacities. ... with Outside GC’s growing list of healthcare clients, with ...
Breaking Biology Technology:VLP Therapeutics Wins the 2015 Life Sciences Impact Grant Award from the Montgomery County Department of Economic Development 2Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 2Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 3Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 4Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 5Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 6Clinical Studies & Research Substantiate Claims That Company's Targeted Healthy Nutritional Products Promote Healthy Lipids, Glucose & Insulin Levels 7VG Life Sciences Granted Key Composition Of Matter Patent 2VG Life Sciences Granted Key Composition Of Matter Patent 3Outside GC Expands Healthcare Team 2
... For the first time in Michigan, a,diseased kidney ... through a single incision., "We made several improvements ... type of procedure routinely," says Craig Rogers, M.D., Henry,Ford,s ... last week using the da Vinci Surgical System, which ...
... Provides Comprehensive Clinical Picture, Improves,Patient-Physician Communications, ... Hemophilia A patients who,use Helixate(R) FS, Antihemophilic ... tracking treatment progress in real time,thanks to ... management system recently introduced by CSL Behring. ...
... BOSTON, Aug. 25 Scimitar Equity, LLC ... Bulletin Board: VOQP), entitled,"Creating Value; Turnaround Leverages ... This review is available at website: ... a New Jersey-based biotechnology company,dedicated to becoming ...
Cached Biology Technology:State's First Single Incision Robotic Kidney Removal Performed at Henry Ford Hospital 2CSL Behring's Innovative HeliTrax(SM) System Helps Physicians Manage Hemophilia A Patients 2CSL Behring's Innovative HeliTrax(SM) System Helps Physicians Manage Hemophilia A Patients 3CSL Behring's Innovative HeliTrax(SM) System Helps Physicians Manage Hemophilia A Patients 4VioQuest Pharmaceuticals, Inc Q2/08 Review Issued by Scimitar Equity, LLC 2
... The Jouan MSC series of Class ... working conditions and certification to the ... regulation ensures that the cabinets cannot ... conditions. Natural lighting, low noise and ...
... Fluoroskan Ascent FL ... fluorometric and luminometric measurement ... long list of advanced ... and Luminoskan Ascent. Fluoroskan ...
Mouse monoclonal [AZ24] to Polo like kinase ( Abpromise for all tested applications)....
... Applied Science, which pioneered the blending of ... Fidelity and Expand Long Template PCR Systems, ... System the first product of a ... new blend combines Taq DNA Polymerase with ...
Biology Products: