Navigation Links
New key to organism complexity identified
Date:1/17/2013

vival of all organisms.

Nogales is a leading authority on electron microscopy and holds joint appointments with Berkeley Lab, the University of California (UC) at Berkeley, and the Howard Hughes Medical Institute (HHMI). She is the corresponding author of a paper describing this research in the journal Cell, titled "Human TFIID Binds to Core Promoter DNA in a Reorganized Structural State." Co-authors are Michael Cianfrocco, George Kassavetis, Patricia Grob, Jie Fang, Tamar Juven-Gershon and James Kadonaga.

The growing number of organisms whose genomes have been sequenced and made available for comparative analyses shows that the total number of genes in an organism's genome is no measure of its complexity. The fruit fly, Drosophila, for example, is far more complex than the nematode worm, Caenorhabditis elegans, but has about 6,000 fewer genes than the worm's 20,000. The total number of human genes is estimated to fall somewhere between 30,000 and 40,000. By comparison, the expression of the genes of both the fruit fly and the nematode are regulated through about 1,000 transcription factors, whereas the human genome boasts approximately 3,000 transcription factors. That multiple transcription factors often act in various combinations with one another creates even more evolutionary roads to organism complexity.

"Although the number of protein coding genes has remained fairly constant throughout metazoan evolution, the number of regulatory DNA elements has increased dramatically," Nogales says. "Our discovery of the existence of two structurally and functionally distinct forms of TFIID suggests a potential molecular mechanism by which a combination of transcription factors can tune the expression level of genes and thereby give rise to a diversity of outcomes."

Despite its critical role in transcription, high-resolution structural information of TFIID has been restricted to to crystal structures of a handfu
'/>"/>

Contact: Lynn Yarris
lcyarris@lbl.gov
510-486-5375
DOE/Lawrence Berkeley National Laboratory
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Production of 5-aminovaleric and glutaric acid by metabolically engineered microorganism
2. Keeping ship hulls free of marine organisms
3. Hearty organisms discovered in bitter-cold Antarctic brine
4. Strange diet for methane consuming microorganisms
5. Plants recognise pathogenic and beneficial microorganisms
6. Small marine organisms big changes could affect world climate
7. Small organisms could dramatically impact worlds climate
8. Unusual symbiosis discovered in marine microorganisms
9. New research suggests bacteria are social microorganisms
10. Why do organisms build tissues they seemingly never use?
11. Progress of arachidonic acid biosynthesis in microorganisms
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New key to organism complexity identified
(Date:6/24/2015)... The biologics safety testing market is growing ... market include growth of the pharmaceutical and biological industries ... the years, the number of drug approvals in North ... FDA approved 225 drug applications and Health Canada approved ... accounted for 3,822 of the pharmaceutical and ...
(Date:6/24/2015)... Research and Markets( ... "Huawei Ascend Mate 7 Fingerprint Sensor - ... Huawei,s technological choice for the fingerprint ... Apple,s and Samsung,s one. The Ascend Mate 7 ... Cards, a main actor in capacitive sensing human ...
(Date:6/23/2015)... June 22, 2015 ... addition of the "Body-Worn Temperature Sensors Market ... and Forecast 2014 - 2020" report to ... analysis of the global body-worn temperature sensors market. ... segmented on the basis of types, care setting, ...
Breaking Biology News(10 mins):Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 2Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 3Biological Safety Testing Market by Application, Product, & Test - Global Forecast to 2019 4Huawei Ascend Mate 7 Fingerprint Sensor - Reverse Costing Analysis 2Body-Worn Temperature Sensors Market - Global Industry Analysis 2
... may not be the answer to mitigating climate change by ... to an international team of plant biologists. The researchers found ... fungi (AMF) -- a type of fungus that is often ... then leads to higher decomposition rates of organic materials, said ...
... the methane on Earth comes from the ocean,s oxygen-rich waters, ... this potent greenhouse gas. Now researchers report that they have ... the most abundant microbes on the planet. The findings ... who made the discovery did not set out to explain ...
... part of the marine ecosystem, fostering biodiversity and protecting ... with pollution and harmful fishing practices, are one of ... One of the solutions to the crisis ... Tel Aviv University,s Department of Molecular Microbiology and Biotechnology, ...
Cached Biology News:Plants' fungi allies may not help store climate change's extra carbon 2Study identifies prime source of ocean methane 2Study identifies prime source of ocean methane 3Viruses could be the key to healthy corals 2
(Date:7/5/2015)... NY (PRWEB) , ... July 06, 2015 , ... For ... If a user had a high-end machine such as a Varian Cary 4000-7000, a ... So widespread was this design that even NIST used them for their SRM-2031 series ...
(Date:7/3/2015)... , ... July 03, 2015 ... ... providing industry-leading products for use in applications such as animal waste reduction, ... treatment plants and restaurant kitchen settings, announced today that it will be ...
(Date:7/3/2015)... , July 3, 2015 ... voivat hakea verkossa osoitteessa  http://www.openinnovationinscience.at ... Open Innovation in Science" -jatkokoulutusohjelmaan ... Boltzmann Gesellschaftin (LBG) tekemän, kansainvälisiä ... mukaan terveystieteiden kaksi suurinta haastetta ...
(Date:7/3/2015)... ... 2015 , ... The Alexander Group, a 30-year old, global ... typically known for its consummate professionalism-- embarks each year in a whacky marketing ... their day jobs. , "Our motto has always been work hard play hard," ...
Breaking Biology Technology:FireflySci Simplifies the Calibration of UV Spectrophotometers with FUV Photometric Accuracy Standards 2FireflySci Simplifies the Calibration of UV Spectrophotometers with FUV Photometric Accuracy Standards 3DryLet to Highlight Benefits of Patented ManureMagic™ at North American Manure Expo in Chambersburg, PA July 14-15, 2015 2Maailman ensimmäinen tiedemiesten koulutukseen suunniteltu avoimen innovaation ohjelma käynnistyy 2Maailman ensimmäinen tiedemiesten koulutukseen suunniteltu avoimen innovaation ohjelma käynnistyy 3The Alexander Group Declares Their Independence with a Bit of Levity 2
... May 11 N30 Pharma (N30), a biopharmaceutical company focused on the discovery ... oxide, announced today that it has completed a $10 million financing and ... , Joining the Company,s ... , , ...
... /PRNewswire-Asia-FirstCall/ -- Yongye International, Inc.,(Nasdaq: YONG ), ("Yongye" or the "Company") a ... China , today announced that it will conduct a conference call at ... for the quarter ended March 31,2010 . , ... To participate in the live conference call, ...
... China , May 11 /PRNewswire-Asia-FirstCall/ -- 3SBio Inc.,(Nasdaq: SSRX ... on researching, developing, manufacturing and marketing,biopharmaceutical products, today announced that it will ... on May 16, 2010 ,at 8:00pm (Eastern). , ... Following ...
Cached Biology Technology:Yongye International Announces Conference Call to Discuss First Quarter Fiscal Year 2010 Results 23SBio Inc. To Report 2010 First Quarter Unaudited Financial Results on May 16, 2010 2
... wide mouth PYREX Fernbach-style culture flask is designed ... to volume ratio. It can also be used ... outside edges to achieve maximal oxygen transfer to ... I.D. and accepts cotton plugs or No. 13 ...
... depletion cocktail is tailored to ... from suspensions of rat spleen ... the StemSep (or compatible 0.5 ... system. The CD4+ T cell ...
Preparation TW--Compatibility: Push-on end cap seals suitable up to 70 C only -Hybridization Tube for Model HB-1D -Comp Dim: 200 80 mm -Material: borosilicate glass -Mfr Desig: Techne FHB-12...
Preparation TW--Compatibility: no end cap seals -Hybridization Tube for Hybrigene -Comp Dim: 240 80 mm -Material: borosilicate glass -Mfr Desig: Techne FHB-15...
Biology Products: