Navigation Links
New imaging advance illuminates immune response in breathing lung
Date:12/20/2010

side the range of their microscope. They then used super-fast imaging with a two-photon microscope to photograph the tissue. Footage was taken 30 times each second, revealing the full progression of cellular participants involved in different biological processes for example: which cells worked together to mount a response to an injury. With that information, the team was able to identify the function of different cell types.

The fast, two-photon microscopy technique previously was developed by the team to monitor immune cells in the lymph nodes and other biological processes. Two-photon microscopy is a light-based high-resolution imaging technology using infrared pulsed lasers to penetrate deep into tissue layers, capturing details as small as one micron (or one ten-thousandth of a centimeter) in diameter. The study uses custom-built microscopes that the team constructed on-site at UCSF.

With more than 20 previously published articles using microscopy, the team is focused on continuing to improve the ability to observe molecules and cells deep within tissues.

Mark R. Looney, MD

"Imaging tissues or organs is ideally done within the living organism and as noninvasively as possible, but there are many challenges," said Mark R. Looney, MD, co-first author and assistant professor in Medicine and Laboratory Medicine at UCSF.

"Light is absorbed and scattered as it passes through tissue, which degrades image quality. And even anesthetized animals have vascular and respiratory movements, complicating the imaging of dynamic processes. Many of these problems are exacerbated in the lung," said Emily Thornton, co-first author and a graduate student in Krummel's laboratory.

Although the lung is a challenging organ to image, it is the site of several important biological functions useful in the study of diseases. For instance, the lung is where the body's internal systems encounter the outside environment through the i
'/>"/>

Contact: Lauren Hammit
lauren.hammit@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. SNM releases new fact sheet on breast cancer and molecular imaging
2. Cheskin Added Value EVP Lee Shupp Discusses Evolving Dynamics of Consumers and Imaging Tech at 6Sight
3. MU brain imaging center provides research for autism, schizophrenia and Parkinsons disease
4. Similarities in imaging the human body, Earths crust focus of conference at UH
5. UNC expands brain imaging study of infants at risk for autism
6. Studies on imaging and tracking transplanted cells
7. Fattysaurus or thinnysaurus? How dinosaurs measure up with laser imaging
8. SNM Symposium on Multimodality Cardiovascular Molecular Imaging
9. Ultrasound imaging now possible with a smartphone
10. First neuroimaging study examining motor execution in children with autism reveals new insights
11. Lyncean Technologies Inc. receives $1.2 M from NCRR to develop new imaging technique
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... Colo., USA A new GSA Bulletin ... the lower Rio Puerco and Chaco Wash in northern ... rings from salt cedar and willow, investigators were able ... or greater. They then combined this data with aerial ... the history of these arroyos. , Arroyos are deep, ...
(Date:9/18/2014)... ANTONIO, September 18, 2014 New research into the ... causes a severe hemorrhagic disease in humans similar to ... essential for CCHFV infection. This discovery has the potential ... the pathogen. , The research, reported in ... Pathogens and conducted by scientists at the Texas ...
(Date:9/18/2014)... the International Space Station ever starts a "frequent flyers" ... status. Recently the orbiting laboratory has hosted increasing numbers ... returned from the space station in April, and another ... third experiment is planned to launch in December. , ... around the world-- and in space. Model organisms can ...
Breaking Biology News(10 mins):Tree rings and arroyos 2Tree rings and arroyos 3Tree rings and arroyos 4Tree rings and arroyos 5Tree rings and arroyos 6Tree rings and arroyos 7Research milestone in CCHF virus could help identify new treatments 2Buzzing with activity: Fruit flies orbit Earth for science 2Buzzing with activity: Fruit flies orbit Earth for science 3Buzzing with activity: Fruit flies orbit Earth for science 4
... has discovered that forest fragmentation poses an even greater ... , Their findings, to be published next week (27 ... National Academy of Sciences USA, summarizes key findings from ... fragmentation. , The Amazon contains the ...
... loses a chunk of its tail fin, it'll grow back ... can replace surprisingly complex body parts. A tail fin, for ... very intricate structure. It is the fish version of an ... re-grow missing tails and other appendages has fascinated veterinary and ...
... immune-boosting substance called an adjuvant, low doses of ... influenza (H9N2) provoked a strong antibody response in ... Institute of Allergy and Infectious Diseases (NIAID), part ... clinical trial of 96 adults was conducted at ...
Cached Biology News:Fragmentation rapidly erodes Amazonian biodiversity 2How does a zebrafish grow a new tail? 2How does a zebrafish grow a new tail? 3H9N2 avian flu vaccine paired with adjuvant provokes strong human immune response at low doses 2
(Date:9/19/2014)... YORK , Sept. 19, 2014  An entire ... forms of inherited neuropathies – Charcot-Marie-Tooth disease (CMT) – ... and legs, causing extreme muscle atrophy, weakness, and foot ... the US and millions worldwide. CMT is a progressive ... of their legs, requiring mobility devices such as leg ...
(Date:9/19/2014)... Barnhardt Manufacturing Company has earned the ... Cotton . The USDA Certified Biobased Product Label verifies ... or exceeds levels set by USDA. Biobased products are ... significant part of agricultural, forestry, or marine ingredients. ... be immediately identified as a USDA certified BioPreferred ...
(Date:9/18/2014)... Washington, USA (PRWEB) September 18, 2014 ... Representatives of a bill designed to stimulate development and ... jobs is being praised by leaders of SPIE, ... bill, the Revitalizing American Manufacturing and Innovation (RAMI) Act, ... The bill’s authors have said they are optimistic that ...
(Date:9/18/2014)... -- Health Enhancement Products, Inc. (OTCQB: HEPI), a Michigan ... metabolic processes, is pleased to announce the addition of a ... Nola E. Masterson , a California -based ... 17, 2014. "We,re very pleased and honored ... Andrew Dahl , President and CEO. "She joins us ...
Breaking Biology Technology:September is Charcot-Marie-Tooth (CMT) Awareness Month - Scheduled events, activities and important partnerships announced throughout the month! 2Barnhardt Manufacturing Company Earns USDA Certified Biobased Product Certification and Label for Organic Cotton 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 2House passage of high-tech manufacturing bill is move toward stronger economy, say SPIE leaders 3Health Enhancement Announces New Board Member In Advance Of Annual Shareholder Meeting 2
... LAIYANG, China, Sept. 27 /PRNewswire-Asia-FirstCall/ -- ... ... ... ,; var first_result; // Results are keyed by longUrl, so we need to grab the first ...
... the specialist in genome customization and subsidiary of Cellectis ... its e-store, with approximately one hundred ready-to-use products available ... website. Launched in 2008, Cellectis bioresearch develops ... which offer a simple, effective means of using Cellectis ...
... Md., Sept. 24 Popular morning talk show LIVE! ... the show,s High Heel-a-thon, Wednesday morning in New York,s Central ... the Foundation for the National Institutes of Health (FNIH) in ... campaign for women,s heart health education and research. ...
Cached Biology Technology:Jiangbo Pharmaceuticals Announces Conference Call to Discuss Results for Fourth Quarter Fiscal 2010 2Jiangbo Pharmaceuticals Announces Conference Call to Discuss Results for Fourth Quarter Fiscal 2010 3Jiangbo Pharmaceuticals Announces Conference Call to Discuss Results for Fourth Quarter Fiscal 2010 4Jiangbo Pharmaceuticals Announces Conference Call to Discuss Results for Fourth Quarter Fiscal 2010 5Jiangbo Pharmaceuticals Announces Conference Call to Discuss Results for Fourth Quarter Fiscal 2010 6Jiangbo Pharmaceuticals Announces Conference Call to Discuss Results for Fourth Quarter Fiscal 2010 7Cellectis Bioresearch Announces Availability of Research Kits Through New Online E-Store 2Cellectis Bioresearch Announces Availability of Research Kits Through New Online E-Store 3LIVE! With Regis and Kelly's 2010 'High Heel-A-Thon' Raises $63,000 for the Foundation for NIH 2LIVE! With Regis and Kelly's 2010 'High Heel-A-Thon' Raises $63,000 for the Foundation for NIH 3
... siSolutions siRNA Custom Synthesis Service ... duplex RNA to knockdown any ... (19 RNA base pairs with ... 27-mers, or other lengths of ...
EDG-1 Western blot control Source: Cell Lysate Application: Western Blotting Control...
Hybridization cassette for one slide...
Request Info...
Biology Products: