Navigation Links
New imaging advance illuminates immune response in breathing lung
Date:12/20/2010

Fast-moving objects create blurry images in photography, and the same challenge exists when scientists observe cellular interactions within tissues constantly in motion, such as the breathing lung. In a recent UCSF-led study in mice, researchers developed a method to stabilize living lung tissue for imaging without disrupting the normal function of the organ. The method allowed the team to observe, for the first time, both the live interaction of living cells in the context of their environment and the unfolding of events in the immune response to lung injury.

The finding impacts disease research, the authors say, because the ability to image the lung and other organs with minimum tissue disruption allows scientists to look deeper into the many physiological aspects of injury and diseases like diabetes or cancer.

"The nature of disease is complex, so if scientists can observe in real-time what's happening in tumors or immune responses as they occur, we can find new ways to intervene," said senior author Max Krummel, PhD, UCSF associate professor of Pathology, whose lab developed the new imaging technique for seeing minute details of cellular interaction in tissues.

"We figured out a method for holding cells still enough to image them without interrupting their normal processes. This enabled us to observe cellular events as they happen naturally rather than the usual way, which is to stop the motion of cellular processes in order to photograph them."

The research, published online this week in Nature Methods, includes videos of these immune cell interactions: http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.1543.html.

To achieve such clear imaging of the fast-moving lung cells, the team developed a custom rig device that applies a gentle amount of suction to the tissue surface, holding the region for viewing in
'/>"/>

Contact: Lauren Hammit
lauren.hammit@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. SNM releases new fact sheet on breast cancer and molecular imaging
2. Cheskin Added Value EVP Lee Shupp Discusses Evolving Dynamics of Consumers and Imaging Tech at 6Sight
3. MU brain imaging center provides research for autism, schizophrenia and Parkinsons disease
4. Similarities in imaging the human body, Earths crust focus of conference at UH
5. UNC expands brain imaging study of infants at risk for autism
6. Studies on imaging and tracking transplanted cells
7. Fattysaurus or thinnysaurus? How dinosaurs measure up with laser imaging
8. SNM Symposium on Multimodality Cardiovascular Molecular Imaging
9. Ultrasound imaging now possible with a smartphone
10. First neuroimaging study examining motor execution in children with autism reveals new insights
11. Lyncean Technologies Inc. receives $1.2 M from NCRR to develop new imaging technique
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... , June 30, 2015 ... has announced the addition of the "Capacitive ... offering. To this date, fingerprint sensing ... technology and fingerprint sensors are well developed. This ... sensing technology. The domain of capacitive ...
(Date:7/2/2015)... , June 25, 2015 ... the addition of the "Natural Language Processing ... (Recognition, IVR, OCR, Pattern & Image Recognition) - ... offering. The key vendors occupying the ... IBM Corporation, Microsoft Corporation, NetBase Solutions, SAS Institute ...
(Date:6/30/2015)... 30, 2015 To bolster its efforts and commitment ... announced today the addition of two new team members. ... advisor and David Raviv will act as head ... Corp.,s commitment to providing the most secure solutions for the ... co-founded Layer 7 Technologies, a provider of security and management ...
Breaking Biology News(10 mins):Worldwide Capacitive Fingerprint Sensors Patent Landscape Market Report 2015-2020 - Main IP Holders include Seiko Epson, AuthenTec, Sony and STMicroelectronics 2Natural Language Processing Market by Type (Rule-Based, Statistical, and Hybrid), Technologies (Recognition, IVR, OCR, Pattern & Image Recognition) - Worldwide Forecast to 2020 2HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 2HYPR Corp. Expands Biometric Authentication Team with Enterprise All Stars 3
... a fledgling industry, now accounts for 50 percent of the ... international team of researchers. And while the industry is more ... on marine resources by consuming large amounts of feed made ... Their findings are published in the Sept. 7 online edition ...
... University,s department of plant pathology is receiving two honors ... pathology, has been named a Fellow of the American ... distinguished contributions to plant pathology or the society. It ... the society,s membership in any one year. The ...
... Monash University biochemists, has discovered evidence at the molecular ... of Darwin,s theory of evolution. Monash University,s ... Australian Research Council and published recently in the prestigious ... general understanding of the evolution of the "machinery" of ...
Cached Biology News:Half of the fish consumed globally is now raised on farms, study finds 2Half of the fish consumed globally is now raised on farms, study finds 3K-State's plant pathology head named fellow of Phytopathology Society 2Evolution still scientifically stable 2
(Date:8/3/2015)... ... August 03, 2015 , ... Sterlitech Corporation ... its comprehensive line of analytical laboratory equipment. With optimized features, such as PTFE-coated ... a chemically resistant and maintenance-free solution for a broad range of vacuum filtration ...
(Date:7/31/2015)... ... 2015 , ... Global Resorcinol Market 2015-2019 is a comprehensive ... global resorcinol industry. The report highlights the various growth prospects and the prevalent ... of primary and secondary inputs from the existing players of the resorcinol market. ...
(Date:7/31/2015)... ... July 31, 2015 , ... R-Biopharm is proud ... partially hydrolyzed gluten in foods, has been accepted by AOAC International as Official ... Gluten in Fermented Cereal-Based Products by R5 Competitive ELISA,” based on a specific ...
(Date:7/30/2015)... AACC welcomed thousands of medical professionals ... Meeting & Clinical Lab Expo in ... showcased revolutionary advancements in clinical testing technology and ... to diagnose patients quickly and accurately and make ... As of Wednesday, July 29, more than ...
Breaking Biology Technology:Sterlitech Launches New Line of Vacuum Pumps 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 2Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 3Resorcinol Market to Grow at 6% CAGR to 2019 Says New Research Report at ReportsnReports.com 4RIDASCREEN® Competitve Gliadin Receives AOAC Official First Action Status 2Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 2Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 3Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 4
... BAX ), will host a quarterly conference call to ... 16, 2009, at 8:30 a.m. Eastern Time (7:30 a.m. Central ... or 703-639-1156 (international). Please dial into the call at ... for the operator to connect you.This call is being webcast ...
... /PRNewswire-FirstCall/ - Vasogen Inc. (NASDAQ: VSGN ; TSX:VAS) today ... February 28, 2009. All dollar amounts referenced herein are in ... our cash and cash equivalents totaled $7.3 million, compared with ... net loss for the three months ended February 28, 2009 ...
... National Healthcare Decisions Day, your choice in times of ... Inc .( www.usoncology.com ), supporting the ... providers, payers and manufacturers to advance cancer care in ... National Healthcare Decisions Day ( ...
Cached Biology Technology:Vasogen Announces First Quarter 2009 Results 2Vasogen Announces First Quarter 2009 Results 3Vasogen Announces First Quarter 2009 Results 4Vasogen Announces First Quarter 2009 Results 5Vasogen Announces First Quarter 2009 Results 6Vasogen Announces First Quarter 2009 Results 7Vasogen Announces First Quarter 2009 Results 8Vasogen Announces First Quarter 2009 Results 9US Oncology Encourages Your Right to Decide 2US Oncology Encourages Your Right to Decide 3
Plasmid expressing Zeocin resistance gene....
...
Hygromycin resistance gene (hph), provided in a pORF plasmid. pORF is an expression plasmid selectable with Ampicillin....
... The FRT-PGK-gb2-neo-FRT template is ... and eukaryotic cells. The FRT-PGK-gb2-neo-FRT template ... a prokaryotic promoter (gb2) for expression of ... a eukaryotic promoter (PGK) for expression of ...
Biology Products: