Navigation Links
New genetic variants associated with lipid levels, risk for coronary artery disease
Date:1/13/2008

Environmental and genetic factors influence a persons blood fat, or lipid levels, important risk factors for coronary artery disease (CAD). While there is some understanding of the environmental contribution, the role of genetics has been less defined. Now, in an international collaboration supported primarily by the National Institutes of Health (NIH), scientists have discovered more than 25 genetic variants in 18 genes connected to cholesterol and lipid levels. Seven of the 18 genes previously had not been connected to these levels, while the 11 others confirm previous discoveries. In the investigation, published online January 13 and in the February print issue of Nature Genetics, the associated genes were found through studies of more than 20,000 individuals and more than 2 million genetic variants, spanning the entire genome. These variants potentially open the door to strategies for the treatment and prevention of CAD.

Heart disease is a leading cause of illness, disability and death in industrialized countries, particularly for older people, says National Institute on Aging (NIA) Director Richard J. Hodes, M.D. We know that certain lifestyle factors like smoking, diet and physical activity greatly affect a persons lipid profiles. This study is an important, basic step in finding the genes that influence lipid levels and heart disease so that we can better understand the genetic contribution to cardiovascular risk.

Cristen Willer, Ph.D., at the University of Michigans School of Public Health, Ann Arbor, and Serena Sanna, Ph.D., at the C.N.R. Institute of Neurogenetics and Neuropharmacology, Monserrato, Italy, and other members of the SardiNIA Study of Aging, including investigators at NIA, conducted the study, along with members of the Finland-United States Investigation of Non-Insulin-Dependent Diabetes Mellitus Genetics (FUSION) study, which included investigators in North Carolina, Michigan, Finland, Los Angeles and from the Nation
'/>"/>

Contact: Megan Homer
nianews3@mail.nih.gov
301-496-1752
NIH/National Institute on Aging
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. Does the desire to consume alcohol and tobacco come from our genetic makeup?
2. Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma
3. Many parents at-risk for cancer disclose genetic test results to children
4. Genetics determine optimal drug dose of common anticoagulant
5. Claims of sex-related differences in genetic association studies often not properly validated
6. American College of Medical Genetics responds to new FDA labeling decision for warfarin
7. UNC study questions FDA genetic-screening guidelines for cancer drug
8. Genome study shines light on genetic link to height
9. Selexis Announces Advanced Approach to Maximize Power of Genetic Elements for Rapid Development of High Performance Cell Lines
10. Genes, Environment and Health Initiative invests in genetic studies, environmental monitoring
11. Rutgers Genetics receives $7.8 million for autism research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)...  Earlier this year Donald Spector , Chairman ... of the most prolific inventors in the world, got ... Smartphones to third party agencies. Spector envisioned this technology ... the earliest known patents in this area. Now major ... child care, elder care and hospital applications. This technology ...
(Date:11/21/2014)...   Atmel® Corporation (NASDAQ: ATML ... technology solutions, today launched the industry,s first family of ... V cc range from 1.7V to 5.5V. The ... 2 C bus communication speeds, and are available with ... ideal for consumer, industrial, computer, and medical applications. ...
(Date:11/18/2014)... , Nov. 17, 2014 The Parenteral Drug ... U.S. regulatory agencies will speak and at least seven more ... Conference at the Omni Shoreham Hotel in Washington ... once again to have significant support from the regulatory agencies ... Europe in our effort to help advance ...
Breaking Biology News(10 mins):Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 2Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 3Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 4FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2
... have a well-earned reputation for being dopey. Sleeping 19 hours ... remaining 5 hours, there doesn,t seem to be much time ... the mating season. Then the males begin bellowing. Benjamin Charlton ... bellow to attract females and to intimidate other males. But ...
... structure rich, poor and sometimes middle instead of ... to Stanford University researchers, it is the very inequities of ... spread of those societies and the displacement of more egalitarian ... researchers used a computer simulation to compare demographic stability and ...
... NCForest Service Southern Research Station (SRS) scientists recently ... (Coweeta) in Western North Carolina to examine the ... the changing weather conditions forecast for the future. ... the journal Ecological Applications, the analysis examines the ...
Cached Biology News:Koalas' bellows boast about size 2Suffering of the poor may have helped societies with class structures spread across globe 2Managing future forests for water 2
(Date:11/22/2014)... CannLabs, Inc. (OTCQB: CANL), the leading ... methodologies relating to cannabis, today announced that it has ... from an existing stockholder of the Company. , ... from one of our existing stockholders,” stated Mark ... help accelerate our planned expansions into the Connecticut and ...
(Date:11/22/2014)... 2014  The element of surprise has been a ... strike without warning. Until now, epidemiologists had nothing to ... outbreak, resulting in suboptimal responses to both the H1N1 ... Photo - http://photos.prnewswire.com/prnh/20141121/160242 ... because virus gene structural changes have been found that ...
(Date:11/21/2014)... (PRWEB) November 20, 2014 Offering a ... Sartorius Entris Balance promotion . The Sartorius Entris ... a durable, high accuracy, and easy-to-maintain balance entry level ... Germany. It was designed to help customer’s bridge the ... a balance that is very durable. Sartorius is the ...
(Date:11/21/2014)... BlueInGreen, LLC ( BlueInGreen® ) ... and PCI, Inc., leading suppliers of ozone process ... selected to provide a new state-of-the-art ozone system ... Noland Wastewater Treatment. The new ozone disinfection ... gas dissolution technology, Pinnacle Ozone’s industry leading Zenith™ ...
Breaking Biology Technology:CannLabs Secures $750,000 Line Of Credit 2Viruses' Advantage of Surprise is Lost 2Pipette.com Announces an Extension on the Sartorius Entris Balance Promotion to the End of 2014 2City of Fayetteville Leads Nation with Innovative Ozone Technology 2City of Fayetteville Leads Nation with Innovative Ozone Technology 3City of Fayetteville Leads Nation with Innovative Ozone Technology 4
... RIDGE, Tenn., July 19, 2010 -- Tomorrow,s television and ... as a result of a process developed by a ... Energy,s Oak Ridge National Laboratory. The synthesis of ... in devices like light-emitting diodes, televisions and solar cells--could ...
... new market research report is available in its catalogue: , , ... Applications. 2009-2015 , , , ... , REPORT DESCRIPTION , ... The ,Stem Cells Market and Applications: (2009-2015), reviews the latest Stem Cells market trends with ...
... create genetically altered mosquitoes that cannot infect humans ... mosquitoes still were capable of transmitting the disease-causing ... for the first time, University of Arizona entomologists ... way that renders them completely immune to the ...
Cached Biology Technology:Polymer synthesis could aid future electronics 2Reportlinker Adds Stem Cells Market And Applications. 2009-2015 2Reportlinker Adds Stem Cells Market And Applications. 2009-2015 3Reportlinker Adds Stem Cells Market And Applications. 2009-2015 4Reportlinker Adds Stem Cells Market And Applications. 2009-2015 5Reportlinker Adds Stem Cells Market And Applications. 2009-2015 6Reportlinker Adds Stem Cells Market And Applications. 2009-2015 7Reportlinker Adds Stem Cells Market And Applications. 2009-2015 8Reportlinker Adds Stem Cells Market And Applications. 2009-2015 9Reportlinker Adds Stem Cells Market And Applications. 2009-2015 10Reportlinker Adds Stem Cells Market And Applications. 2009-2015 11Reportlinker Adds Stem Cells Market And Applications. 2009-2015 12Reportlinker Adds Stem Cells Market And Applications. 2009-2015 13Reportlinker Adds Stem Cells Market And Applications. 2009-2015 14Reportlinker Adds Stem Cells Market And Applications. 2009-2015 15Reportlinker Adds Stem Cells Market And Applications. 2009-2015 16Reportlinker Adds Stem Cells Market And Applications. 2009-2015 17Reportlinker Adds Stem Cells Market And Applications. 2009-2015 18Reportlinker Adds Stem Cells Market And Applications. 2009-2015 19Reportlinker Adds Stem Cells Market And Applications. 2009-2015 20Reportlinker Adds Stem Cells Market And Applications. 2009-2015 21Reportlinker Adds Stem Cells Market And Applications. 2009-2015 22Reportlinker Adds Stem Cells Market And Applications. 2009-2015 23Reportlinker Adds Stem Cells Market And Applications. 2009-2015 24Reportlinker Adds Stem Cells Market And Applications. 2009-2015 25Reportlinker Adds Stem Cells Market And Applications. 2009-2015 26Reportlinker Adds Stem Cells Market And Applications. 2009-2015 27Reportlinker Adds Stem Cells Market And Applications. 2009-2015 28Reportlinker Adds Stem Cells Market And Applications. 2009-2015 29Reportlinker Adds Stem Cells Market And Applications. 2009-2015 30Reportlinker Adds Stem Cells Market And Applications. 2009-2015 31Reportlinker Adds Stem Cells Market And Applications. 2009-2015 32Reportlinker Adds Stem Cells Market And Applications. 2009-2015 33The first malaria-proof mosquito 2The first malaria-proof mosquito 3
... 0.15M NaCl, 20mM MOPS, pH 7.5, ... 1mM EGTA, 10 Properites: For selective ... DEAE chromatography, divalent cation activation plus ... Quality Assurance: routinely evaluated by dephosphorylation ...
Mouse monoclonal [6G11] to Cytohesin 1 + 2 ( Abpromise for all tested applications)....
HNF-1 Purified Anti-Mouse, Anti-Rat, Anti-Rabbit, Anti-Human clone 2, Isotype Mouse IgG 1 , 50 µg Consult technical datasheet for details....
Recombinant Porcine IL-1 alpha/IL-1F1, CF...
Biology Products: