Navigation Links
New gene variant identified for nondiabetic end stage renal disease in African-Americans
Date:9/14/2008

riations has disease and not everyone with disease has the variations. Therefore, it is imperative that we understand what other modifiable risk factors are interacting with the genetic risk factors to cause disease."

For the study, researchers used a technique known as admixture mapping to survey genomes of 1,372 African Americans with ESRD and a control group of about 800 African Americans without ESRD. The study identified several alleles, or variations, in the MYH9 gene that were highly associated with non-diabetic ESRD but not diabetic ESRD. These variants were not associated with diabetic ESRD. Even though the variations identified in this study are present in many populations, they are more frequent among individuals with West African ancestry.

"This finding suggests that the mechanisms leading from onset of chronic kidney disease to kidney failure may differ based on the inciting cause," said study author Rulan S. Parekh, MD, associate professor Johns Hopkins School of Medicine and the Welch Center. "Discovery of the gene and its association with kidney disease will lead to future studies to better understand the biology of kidney disease progression and ultimately may direct drug therapy and potential screening of patients."


'/>"/>

Contact: Tim Parsons
tmparson@jhsph.edu
410-955-7619
Johns Hopkins University Bloomberg School of Public Health
Source:Eurekalert

Page: 1 2

Related biology news :

1. Genetic variant increases triglyceride levels in Asian-Americans
2. Genetic variant mimics effect of heart failure medications
3. New vaccine may give long-term defense against deadly bird flu and its variant forms
4. Genetic variants of USF1 are associated with the increased risk for cardiovascular disease
5. Gene variant increases breast cancer risk
6. New genetic variants associated with lipid levels, risk for coronary artery disease
7. Scientists associate 6 new genetic variants with heart disease risk factor
8. Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity
9. Breastfeeding boost IQ in infants with helpful genetic variant
10. New genetic variant associated with prostate cancer in African-Americans
11. Genetic variant linked to odor perception
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/2/2015)... March 2, 2015 Synaptics Inc. (NASDAQ: ... human interface solutions, today announced a new implementation ... to enable rapid and secure transactions and reliable ... gaming is a turnkey solution providing mouse and ... quickly integrate fingerprint ID solutions into their product ...
(Date:3/2/2015)... March 2, 2015   Neurotechnology , a provider ... the SentiGaze Software Development Kit (SDK). The ... that use off-the-shelf webcams to track eye movements and ... a monitor. Heatmaps can be used for applications such ... online advertising. The SDK can also be used to ...
(Date:2/24/2015)... 2015 This report analyzes the worldwide markets for ... analytics for the US, Canada , ... Asia-Pacific , Middle East , ... forecasts are provided for the period 2013 through 2020. Also, ... data and analytics are derived from primary and secondary research. ...
Breaking Biology News(10 mins):Synaptics Unveils New Fingerprint ID Solution for Gamers 2Synaptics Unveils New Fingerprint ID Solution for Gamers 3Neurotechnology Releases SentiGaze SDK for Eye Movement Tracking Using Ordinary Webcams 2Neurotechnology Releases SentiGaze SDK for Eye Movement Tracking Using Ordinary Webcams 3World Iris Biometrics Industry 2World Iris Biometrics Industry 3World Iris Biometrics Industry 4World Iris Biometrics Industry 5World Iris Biometrics Industry 6World Iris Biometrics Industry 7World Iris Biometrics Industry 8World Iris Biometrics Industry 9World Iris Biometrics Industry 10World Iris Biometrics Industry 11
... MANHATTAN, KAN. -- Veterinary medicine students are ... medicine students, undergraduate students and the general population, ... State University researchers. Mac Hafen, therapist and ... Veterinary Medicine, and researchers from Kansas State University, ...
... This release is available in German . ... They can reproduce almost all cell types and thus offer ... Parkinson,s. However, it would appear that their use is not ... iPS cells, disease-causing mutations can creep into the genetic material. ...
... Gripping tightly to a tree trunk, at first sight ... this animal leaps it launches into a graceful glide, spreading ... to cover distances of up to 150m. So, when Greg ... California, Berkeley, USA, were looking around for a mammal to ...
Cached Biology News:Research finds veterinary medicine students experience higher depression levels than peers 2Research finds veterinary medicine students experience higher depression levels than peers 3Mitochondrial genome mutates when reprogrammed 2Mitochondrial genome mutates when reprogrammed 3Colugos glide to save time, not energy 2
(Date:3/3/2015)... Santa Clara, California (PRWEB) March 03, 2015 ... and development service company, has launched a new Life ... research reagents for preclinical research. , The first ... monoclonal antibody isotype controls, and soon to be released ... The company will continue to expand their life science ...
(Date:3/3/2015)... , March 3, 2015 Fried, Frank, Harris, ... I.D. Lewis has joined the Firm as a ... the New York office. Mr. ... matters, as well as other intellectual property and general ... Mr. Lewis represents both plaintiffs and defendants in a ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 HubCast® Inc. ... Chain, today announced the expansion of its Global Print ... print to 850 the world’s largest cities across 75 ... extends to 137 countries providing global enterprises ease, speed, ... procurement process from online order to real-world delivery at ...
(Date:3/3/2015)... March 3, 2015  Thingee Corporation, a software development ... a presentation entitled, "Technology Adoption: Making Reps, Lives Easier" ... Innovations and Technology ,  in Deerfield Beach, ... 13, 2015. Audiences looking to learn how technology can ... to be in the audience for the Thingee presentation. ...
Breaking Biology Technology:Crown Bioscience Launches Life Science Product Catalog 2Leading Patent Attorney Jeffrey Lewis Joins Fried Frank's Intellectual Property Litigation Practice 2Leading Patent Attorney Jeffrey Lewis Joins Fried Frank's Intellectual Property Litigation Practice 3HubCast Expands Global Print Supply Chain: Launches New Product Suite 2HubCast Expands Global Print Supply Chain: Launches New Product Suite 3HubCast Expands Global Print Supply Chain: Launches New Product Suite 4Thingee to present at 11th Annual Synergistix Users Conference 2
... 24 Glasses embedded with a telescope,promise to ... to drive and do,other activities requiring sharper distance ... of these innovative glasses,over earlier devices in an ... Biomedical Optics, mailed to subscribers in print form ...
... Laboratory,(IL) today announced that Broadlane, Inc., a leading ... a five-year contract covering its,critical care products and ... clients more than 915 acute care hospitals, more ... physician practices., The contract covers IL,s portfolio ...
... YORK, July 24 American Oriental,Bioengineering, Inc. (NYSE: ... quarter 2008 financial results on Monday, August 11, 2008, ... conference call at 5:00 pm ET on August 11,2008 ... may,access the call by dialing 1-800-599-9816 or 1-617-847-8705 for,international ...
Cached Biology Technology:Telescope Embedded in Spectacle Lens Promises to Make Driving Easier for Visually Impaired 2Telescope Embedded in Spectacle Lens Promises to Make Driving Easier for Visually Impaired 3Instrumentation Laboratory Announces Contract for Multi-Parameter Testing Products with Broadlane 2
RECOMBINANT EQUINE TNF ALPHA Product Type: Recombinant Protein...
... Buffers are supplied as 10X concentrated solutions. REact ... each of the REact buffers and one 250 ... of four 1 ml vials of REact 1 ... Buffer four 1 ml vials of REact 3 ...
Porcine TNF-alpha/TNFSF1A ELISpot Development Module...
5-bromo-4-chloro-3-indolyl b -D-galactopyranoside (X-Gal)...
Biology Products: