Navigation Links
New formula invented for microscope viewing, substitutes for federally controlled drug
Date:5/17/2013

Researchers at Rutgers, The State University of New Jersey, and City University of New York have invented a proprietary new formulation called VisikolTM that effectively clears organisms to be viewed under microscopes. Visikol can be used in place of chloral hydrate, which is one of the few high-quality clearing solutions currently available but which is tightly regulated by the Drug Enforcement Administration (DEA) due to its use as a narcotic.

Clearing solutions, or clearing agents, are vital for viewing organisms under a microscope. Without them, microscope images become refracted and scattered, impairing the clarity of vision. Clearing solutions are used to identify specimens and examine their anatomy by "clearing" them, increasing the transparency of the specimen by rendering some components of a specimen invisible in order to better view other components of interest.

One of the most common clearing solutions is chloral hydrate, which is used for everything from studying plant organelles to authenticating herbal plant species for medicinal purposes. Its popularity in the research community, government, and industry stems from its high refractive index, which allows a high magnitude of light to pass through the medium and make specimens crystal clear under the microscope.

However, chloral hydrate is difficult and expensive to obtain, as it is regulated by the DEA as a Schedule IV controlled substance. Chloral hydrate is prescribed medically as a sedative, depressant, pain reliever, and hypnotic, and overdoses can lead to serious health issues, including fatal heart conditions. Chloral hydrate has also found use as an illicit drug, and has been used in sexual assaults. Thus, possession of chloral hydrate requires costly, annual permits and time-consuming paperwork. Despite its advantages for research and industry, chloral hydrate is an impractical, and sometimes impossible, choice for scientists.

To replace c
'/>"/>

Contact: Beth Parada
apps@botany.org
American Journal of Botany
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study shows botanical formula fights prostate cancer
2. Reduced glycerin formulation of tenofovir vaginal gel safe for rectal use
3. Hazelnuts improve infant formula
4. Liquid glucagon formulation discovered for potential use in artificial pancreas systems
5. Maths formula leads researchers to source of pollution
6. Breast milk promotes a different gut flora growth than infant formulas
7. UC Riverside developing biofuel formulations for California
8. New, cost-cutting approach to formulating pest-killing fungi
9. Human eye inspires clog-free ink jet printer invented by MU researcher
10. Beyond the microscope: Identifying specific cancers using molecular analysis
11. Nature: Microscope looks into cells of living fish
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... chronic inflammatory disorders among people of lower socioeconomic status ... to the microbes that thrive in rural environments, according ... in the journal Clinical & Experimental Immunology , ... less access to green spaces may be more apt ... system dysfunction. , When our immune systems are working ...
(Date:4/23/2014)... diagnosed with Huntington,s disease, most in their mid-thirties ... physical, and behavioral decline within two decades. "Mutant" ... the genetic disease, have been the primary focus ... according to new research from Prof. Gerardo Lederkremer ... Department of Cell Research and Immunology, in collaboration ...
(Date:4/23/2014)... NY. (Apr. 23, 2014) People who have had ... to restore neurological function. However, a study conducted in ... of Cell Transplantation , but is currently freely ... http://www.ingentaconnect.com/content/cog/ct/pre-prints/content-ct1168Chen , has found that when one group of ... (PBSCs) injected directly into the brain and a similar ...
Breaking Biology News(10 mins):Rural microbes could boost city dwellers' health 2Rural microbes could boost city dwellers' health 3On the defensive 2On the defensive 3Autologous stem cell therapy improves motor function in chronic stroke victims 2
... Society by Joaquin Marro is a wide-ranging and accessible ... strategies and concepts that help us understand the boundaries ... and biology on the other. From cooperation ... addresses many of the topics belonging to the broad ...
... Even though multiple sclerosis is largely caused by genetic ... is lower than previously assumed. This is the conclusion ... scientific journal Brain . In the present ... risks for multiple sclerosis (MS) by using population registers ...
... nanotechnology we,ve gotten electronic skin, or e-skin, and electronic ... of electronic whiskers. Researchers with Berkeley Lab and the ... from composite films of carbon nanotubes and silver nanoparticles ... rats. These new e-whiskers respond to pressure as slight ...
Cached Biology News:Modest familial risks for multiple sclerosis 2E-whiskers 2
(Date:1/15/2014)... A study has been launched to test whether technology ... help to tackle the problem of obesity.  This unique healthcare ... based in Stowmarket) and academics at University Campus Suffolk is ... which is inspired by equipment used to collect data about ...
(Date:1/15/2014)... Arizona (PRWEB) January 15, 2014 2013 ... for Scottsdale’s Brain State Technologies®. They saw continued independent ... Medical Center who were awarded a $1 million grant ... published in “Brain and Behavior” a peer reviewed journal, ...
(Date:1/14/2014)... Carahsoft and CDS Federal Services have ... at 2pm EST (11am PST), “Natural Language Processing: Converting ... how technology can turn raw, heterogeneous data into actionable ... The online webinar will last approximately one hour. , ...
(Date:1/14/2014)... Texas , Jan. 14, 2014 The ... and research medicinal plants and therapeutic derivatives thereof ... health professionals, and researchers about the challenges of ... http://photos.prnewswire.com/prnh/20100430/DC95601LOGO ) The Society ...
Breaking Biology Technology:Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 2Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 3Formula 1 Technology Tackles Obesity in Unique Healthcare Partnership 4Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 2World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 3World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 4World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 5World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 6World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 7World's Largest Group of Medicinal Plant Researchers Endorses ABC-AHP-NCNPR Botanical Adulterants Program 8
... SAN FRANCISCO, Oct. 12 In a study presented ... Chemotherapy (ICAAC), researchers used a mobile, automated UV device ... (VA) Medical Center in Ohio and analyzed its ability ... device, known as Tru-D, uses reflected UVC germicidal energy ...
... Oct. 12 ImaginAb, Inc. and BZL Biologics, LLC ... for the field of diagnostic imaging for PET and ... agreement with BZL as we believe that huJ591 will ... the diagnosis and management of prostate cancer. BZL,s technology ...
... in Europe,s healthcare industry were recognised at Frost ... held in London on 8th October 2009. 17 ... prestigious event. , (Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO ) ... including drug discovery technologies, healthcare and life sciences ...
Cached Biology Technology:Researchers Present 'a Novel, Automated, Efficient Environmental Disinfection Technology that Significantly Reduces C. difficile, VRE and MRSA Contamination' 2Researchers Present 'a Novel, Automated, Efficient Environmental Disinfection Technology that Significantly Reduces C. difficile, VRE and MRSA Contamination' 3ImaginAb, Inc. and BZL Biologics, LLC Conclude Licensing Agreement for Imaging Rights to huJ591/Prostate-Specific Membrane Antigen (PSMA) 2Frost & Sullivan's 2009 Excellence in Healthcare Awards Banquet Honours Industry's Top Performers 2Frost & Sullivan's 2009 Excellence in Healthcare Awards Banquet Honours Industry's Top Performers 3
ERalpha (Ser 104/106)...
... Alkaline Phosphatase, Calf Intestinal (CIAP), catalyzes the ... and ribo- and deoxyribonucleoside triphosphates. This enzyme ... of linearized cloning vector DNA by removing ... also be used for the dephosphorylation of ...
Mouse CXCR3 Allophycocyanin MAb (Clone 220803)...
Homo sapiens palladin...
Biology Products: