Navigation Links
New formula invented for microscope viewing, substitutes for federally controlled drug
Date:5/17/2013

Researchers at Rutgers, The State University of New Jersey, and City University of New York have invented a proprietary new formulation called VisikolTM that effectively clears organisms to be viewed under microscopes. Visikol can be used in place of chloral hydrate, which is one of the few high-quality clearing solutions currently available but which is tightly regulated by the Drug Enforcement Administration (DEA) due to its use as a narcotic.

Clearing solutions, or clearing agents, are vital for viewing organisms under a microscope. Without them, microscope images become refracted and scattered, impairing the clarity of vision. Clearing solutions are used to identify specimens and examine their anatomy by "clearing" them, increasing the transparency of the specimen by rendering some components of a specimen invisible in order to better view other components of interest.

One of the most common clearing solutions is chloral hydrate, which is used for everything from studying plant organelles to authenticating herbal plant species for medicinal purposes. Its popularity in the research community, government, and industry stems from its high refractive index, which allows a high magnitude of light to pass through the medium and make specimens crystal clear under the microscope.

However, chloral hydrate is difficult and expensive to obtain, as it is regulated by the DEA as a Schedule IV controlled substance. Chloral hydrate is prescribed medically as a sedative, depressant, pain reliever, and hypnotic, and overdoses can lead to serious health issues, including fatal heart conditions. Chloral hydrate has also found use as an illicit drug, and has been used in sexual assaults. Thus, possession of chloral hydrate requires costly, annual permits and time-consuming paperwork. Despite its advantages for research and industry, chloral hydrate is an impractical, and sometimes impossible, choice for scientists.

To replace c
'/>"/>

Contact: Beth Parada
apps@botany.org
American Journal of Botany
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study shows botanical formula fights prostate cancer
2. Reduced glycerin formulation of tenofovir vaginal gel safe for rectal use
3. Hazelnuts improve infant formula
4. Liquid glucagon formulation discovered for potential use in artificial pancreas systems
5. Maths formula leads researchers to source of pollution
6. Breast milk promotes a different gut flora growth than infant formulas
7. UC Riverside developing biofuel formulations for California
8. New, cost-cutting approach to formulating pest-killing fungi
9. Human eye inspires clog-free ink jet printer invented by MU researcher
10. Beyond the microscope: Identifying specific cancers using molecular analysis
11. Nature: Microscope looks into cells of living fish
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/18/2014)... suspected genetic conditions, a certain type of exome sequencing ... than traditional molecular diagnostic methods, according to a study ... released to coincide with the American Society of Human ... protein­coding region of the genome (the complete set of ... organism), has been rapidly applied in research settings and ...
(Date:10/16/2014)... on the human body. Battles are won, lost ... cancer, this stalemate—known as tumor dormancy—can last up ... phenomena that is poorly understood. , A ... Salvatore Torquato, a Professor of Chemistry at Princeton ... dormancy and the switch to a malignant state. ...
(Date:10/16/2014)... severe respiratory tract infections and worldwide claims the ... VIB and Ghent University have succeeded in developing ... virus infection. , Xavier Saelens (VIB/UGent): "We ... way for the development of a novel approach ... suffering in numerous small children and elderly people." ...
Breaking Biology News(10 mins):Study examines type of exome sequencing and molecular diagnostic yield 2Study examines type of exome sequencing and molecular diagnostic yield 3Modeling tumor dormancy 2New perspectives for development of an RSV vaccine 2
... 235 types of rice from around the world has found its glycemic ... varieties scoring a low to medium GI.,This finding is good news because ... for the average consumer, it also means people with diabetes, or at ... healthy, low GI diet. The study found that the GI of ...
... July 9, 2012 Bovine spongiform encephalopathy (BSE, or "mad ... portions of the brain to turn sponge-like. This transmissible ... of protein known as a prion, rather than by a ... signs of illness is about 60 months. Little is known ...
... centuries that copper is a potent weapon against infection. ... urinary tract infections "know" this, too, and steal copper ... Blocking this thievery with a drug may ... to researchers at Washington University School of Medicine in ...
Cached Biology News:Study reveals good news about the GI of rice 2Study finds 'mad cow disease' in cattle can spread widely in ANS before detectable in CNS 2Urinary tract infections steal from hosts' defense arsenals 2
(Date:10/20/2014)... PureTech , a science and ... problems, announced today the closing of a $55 ... Invesco Perpetual, a $120 Billion group of funds. ... existing pipeline forward and to advance new healthcare ... creativity to really go for the big ideas ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 Local veterinary ... in an investigational study of donor stem cells for ... stem cell therapy and has performed clinical stem cell ... study is to determine if a single injection of ... joints can help reduce pain and inflammation in the ...
(Date:10/19/2014)... 19, 2014 NextCODE Health, which enables clinicians and ... real time, today announced the launch of its new genomic ... at the American Society of Human Genetics (ASHG) annual meeting ... sign up and apply for free beta access, visit ... benefits can be viewed here . The ...
(Date:10/19/2014)... The Asia-Pacific Speech Analytics market report ... with analysis and forecast of revenue. This market is ... $208 million by 2019, at a Compound Annual Growth ... Browse through the TOC of the Asia-Pacific Speech Analytics ... analysis provided. It also provides a glimpse of the ...
Breaking Biology Technology:PureTech Announces Expansion with Oversubscribed $55M Funding Round 2PureTech Announces Expansion with Oversubscribed $55M Funding Round 3PureTech Announces Expansion with Oversubscribed $55M Funding Round 4PureTech Announces Expansion with Oversubscribed $55M Funding Round 5PureTech Announces Expansion with Oversubscribed $55M Funding Round 6Cascade Veterinary Referral Center Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 2The NextCODE Exchange: The first global, real-time system for sharing full-resolution genomic data 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 2The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 3The Asia-Pacific Speech Analytics market is estimated to reach $208 million by 2019 - New Report by MicroMarket Monitor 4
... David T. Corr, assistant professor in the Department ... a Faculty Early Career Development Award (CAREER) from the ... the five-year, $449,999 award to further his research into ... tissues. His work aims to harness the cell,s natural ...
... ,, TAI,AN, China , May 13 ... "Company"), a leading,plasma-based biopharmaceutical company in China , today announced that it ... May 17, 2010 , to discuss,the first quarter 2010 financial results. , ... Hosting the call will ...
... , LANSDALE, Pa. , May 13 A guide ... released by Hayes, Inc. This comprehensive resource is designed to equip physicians ... evidence-based information to help them understand the complexities of BRCA1/2 ... , ...
Cached Biology Technology:Rensselaer Polytechnic Institute Professor David Corr receives NSF CAREER award 2China Biologic Products Schedules Conference Call to Discuss First Quarter 2010 Results 2China Biologic Products Schedules Conference Call to Discuss First Quarter 2010 Results 3Hayes, Inc. Releases Guide to BRCA1 and BRCA2 Genetic Testing 2
Applications: (+) Immunocytochemistry and immunohistochemistry...
Anti-Rat KAPPA/LAMBDA:HRP, Clone MARK-1/MARL-15, Monoclonal Antibody...
MOUSE ANTI RAT KAPPA/LAMBDA:HRP Immunogen: MARK-1: Rat kappa light chains (IR202 and IR968)MARL-15: Rat lambda light chains (RH58, IR31)...
Request Info...
Biology Products: