Navigation Links
New formula invented for microscope viewing, substitutes for federally controlled drug
Date:5/17/2013

Researchers at Rutgers, The State University of New Jersey, and City University of New York have invented a proprietary new formulation called VisikolTM that effectively clears organisms to be viewed under microscopes. Visikol can be used in place of chloral hydrate, which is one of the few high-quality clearing solutions currently available but which is tightly regulated by the Drug Enforcement Administration (DEA) due to its use as a narcotic.

Clearing solutions, or clearing agents, are vital for viewing organisms under a microscope. Without them, microscope images become refracted and scattered, impairing the clarity of vision. Clearing solutions are used to identify specimens and examine their anatomy by "clearing" them, increasing the transparency of the specimen by rendering some components of a specimen invisible in order to better view other components of interest.

One of the most common clearing solutions is chloral hydrate, which is used for everything from studying plant organelles to authenticating herbal plant species for medicinal purposes. Its popularity in the research community, government, and industry stems from its high refractive index, which allows a high magnitude of light to pass through the medium and make specimens crystal clear under the microscope.

However, chloral hydrate is difficult and expensive to obtain, as it is regulated by the DEA as a Schedule IV controlled substance. Chloral hydrate is prescribed medically as a sedative, depressant, pain reliever, and hypnotic, and overdoses can lead to serious health issues, including fatal heart conditions. Chloral hydrate has also found use as an illicit drug, and has been used in sexual assaults. Thus, possession of chloral hydrate requires costly, annual permits and time-consuming paperwork. Despite its advantages for research and industry, chloral hydrate is an impractical, and sometimes impossible, choice for scientists.

To replace c
'/>"/>

Contact: Beth Parada
apps@botany.org
American Journal of Botany
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study shows botanical formula fights prostate cancer
2. Reduced glycerin formulation of tenofovir vaginal gel safe for rectal use
3. Hazelnuts improve infant formula
4. Liquid glucagon formulation discovered for potential use in artificial pancreas systems
5. Maths formula leads researchers to source of pollution
6. Breast milk promotes a different gut flora growth than infant formulas
7. UC Riverside developing biofuel formulations for California
8. New, cost-cutting approach to formulating pest-killing fungi
9. Human eye inspires clog-free ink jet printer invented by MU researcher
10. Beyond the microscope: Identifying specific cancers using molecular analysis
11. Nature: Microscope looks into cells of living fish
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/20/2015)... and Markets ( http://www.researchandmarkets.com/research/vkzvcs/iris_biometrics ) has announced the ... Report" report to their offering. This report ... The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... . Annual estimates and forecasts are provided ...
(Date:3/17/2015)... , March 17, 2015 MedNet ... specializing in clinical study management systems, is pleased ... attendance at ARENA,s Outsourcing in Clinical Trials Southeast ... event provides an excellent forum for MedNet to ... and affordable software-as-a-service (SaaS) eClinical technology platform. ...
(Date:3/16/2015)... , March 16, 2015 ... Systems GmbH will present groundbreaking innovations in biometric ... Hanover, Germany .      (Photo: ... latest biometric innovation is well at the forefront: ... generation e-gate made in Germany ...
Breaking Biology News(10 mins):Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 2Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 3Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 4Iris Biometrics - Global Strategic Business Report 2015: System & Network Access Control - A Robust Market Opportunity in the Offing 5Connect With MedNet Solutions At Outsourcing In Clinical Trials Southeast 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 2DERMALOG Presents its Latest Biometric Innovations at the Hannover CeBIT Exhibition, 16 - 20 March 2015 3
... the world have forced many species to the brink of ... causes that are still not fully understood, researchers conclude in ... factor is often missing the larger picture, they said, and ... consider the totality of causes or could even make ...
... - Call them the Jason Bournes of the bacteria world. ... bacteria avoid antibiotic treatments by essentially shutting down and hiding ... professor in the Artie McFerrin Department of Chemical Engineering at ... is explained in the online April edition of Nature ...
... a research paper titled "Expanding the Diversity of Mycobacteriophages: ... PLoS ONE , a peer-reviewed online journal published ... included 12 Washington University undergraduates who had participated as ... University in St. Louis. Phages are viruses that ...
Cached Biology News:Catastrophic amphibian declines have multiple causes, no simple solution 2Catastrophic amphibian declines have multiple causes, no simple solution 3'Going off the grid' helps some bacteria hide from antibiotics 2'Going off the grid' helps some bacteria hide from antibiotics 3Phage hunting students publish in PLoS ONE 2Phage hunting students publish in PLoS ONE 3
(Date:3/30/2015)... 30, 2015 /CNW/ - A new national Labour Market ... and demographic profiles of new graduates entering the biotech ... Building Careers for New Grads in Biotech," is sponsored ... Pharmaceutical Companies (Rx&D) and features data collected from new ... subsidy program from 2013 to 2015. Among ...
(Date:3/30/2015)... BELLINGHAM, Washington, USA (PRWEB) March 29, 2015 ... Europe and the United States and plenary talks by ... for SPIE Optics + Optoelectronics next month ... 700 technical presentations in 17 conferences alongside a two-day ... optics and photonics , the event will run 13-16 ...
(Date:3/30/2015)... , March 30, 2015 ... auf    Richmond Pharmacology ist das erste ... Amyloidose-Zentrum am Royal Free Hospital in ... zur Untersuchung eines RNAi-Therapeutikums Studienversuche an einem Patienten ... von Transthyretin vermittelter Amyloidose entwickelt (ATTR), einer seltenen ...
(Date:3/29/2015)... , March 29, 2015  Caris ... study data in small cell cervical cancer ... Caris Molecular Intelligence®, the company,s panomic, comprehensive ... gene mutations which may explain sensitivities and ... that identification of certain biomarkers may guide ...
Breaking Biology Technology:New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 2New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 3New Report on Graduates in Canadian Biotech Industry Sheds Light on Hiring Practices 4Laser Energy Advances Among Reports Set for SPIE Optics + Optoelectronics 2Laser Energy Advances Among Reports Set for SPIE Optics + Optoelectronics 3Study Using Caris Molecular Intelligence Multiplatform Tumor Profiling Identifies Potential Treatment Strategies for Small Cell Cervical Cancer 2Study Using Caris Molecular Intelligence Multiplatform Tumor Profiling Identifies Potential Treatment Strategies for Small Cell Cervical Cancer 3
... March 19 /Xinhua-PRNewswire-FirstCall/ -- 3SBio Inc.,(Nasdaq: ... leading China-based,biotechnology company focused on researching, developing, ... appointment of,Dr. David Chen to the newly ... Operating Officer, effective immediately. Dr. Chen most ...
... Genomas(R), a,biomedical company advancing DNA-guided medicine and personalized,healthcare, ... I-II Small,Business Innovation Research (SBIR) Grant totaling $1.2 ... Safety and Efficacy," was,awarded by the National Institute ... the most prescribed drugs in the world. Drugs ...
... 19 AdvanDx announced it received,Frost & ... Award in the,field of rapid in-vitro molecular ... on AdvanDx,s easy-to-use, molecular-based,PNA FISH(TM) diagnostics to ... days. The rapid PNA FISH results enable ...
Cached Biology Technology:3SBio Inc. Announces Promotion of David Chen as Chief Operating Officer 2Genomas Awarded $1.2 Million NIH SBIR Grant to Develop DNA-Guided System for Management of Statin Therapy 2AdvanDx Receives Frost & Sullivan's Rapid In-Vitro Diagnostic Technology Innovation of the Year Award 2AdvanDx Receives Frost & Sullivan's Rapid In-Vitro Diagnostic Technology Innovation of the Year Award 3AdvanDx Receives Frost & Sullivan's Rapid In-Vitro Diagnostic Technology Innovation of the Year Award 4
... Antibody Binding: High, 400 ng IgG/cm ... , Binding Interaction: Hydrophobic/Ionic , Performance Certified: ... Flat , Maximum Well Volume: 360 µl ... ,Features, Special optically clear polystyrene ...
... of Caspase/DIABLO Liquid. In 100 mM ... CYCLES. Amino acid residues 56 - 239 of ... sequence was expressed in and purified from ... with cytochrome c during apoptosis and ...
... JASCO offers a dedicated system for ... modular LC-1500 series of HPLC instrumentation. JASCO ... enhance the capability of the system: ,- ... chromatography and extraction procedures using carbon dioxide ...
... was originally formulated to support the growth ... gum moth,Antherea eucalypti. The medium is a ... resembleAnthereahemolymph. The cell lines established by Grace ... lines developed. The basal medium, when properly ...
Biology Products: