Navigation Links
New formula invented for microscope viewing, substitutes for federally controlled drug
Date:5/17/2013

Researchers at Rutgers, The State University of New Jersey, and City University of New York have invented a proprietary new formulation called VisikolTM that effectively clears organisms to be viewed under microscopes. Visikol can be used in place of chloral hydrate, which is one of the few high-quality clearing solutions currently available but which is tightly regulated by the Drug Enforcement Administration (DEA) due to its use as a narcotic.

Clearing solutions, or clearing agents, are vital for viewing organisms under a microscope. Without them, microscope images become refracted and scattered, impairing the clarity of vision. Clearing solutions are used to identify specimens and examine their anatomy by "clearing" them, increasing the transparency of the specimen by rendering some components of a specimen invisible in order to better view other components of interest.

One of the most common clearing solutions is chloral hydrate, which is used for everything from studying plant organelles to authenticating herbal plant species for medicinal purposes. Its popularity in the research community, government, and industry stems from its high refractive index, which allows a high magnitude of light to pass through the medium and make specimens crystal clear under the microscope.

However, chloral hydrate is difficult and expensive to obtain, as it is regulated by the DEA as a Schedule IV controlled substance. Chloral hydrate is prescribed medically as a sedative, depressant, pain reliever, and hypnotic, and overdoses can lead to serious health issues, including fatal heart conditions. Chloral hydrate has also found use as an illicit drug, and has been used in sexual assaults. Thus, possession of chloral hydrate requires costly, annual permits and time-consuming paperwork. Despite its advantages for research and industry, chloral hydrate is an impractical, and sometimes impossible, choice for scientists.

To replace c
'/>"/>

Contact: Beth Parada
apps@botany.org
American Journal of Botany
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Study shows botanical formula fights prostate cancer
2. Reduced glycerin formulation of tenofovir vaginal gel safe for rectal use
3. Hazelnuts improve infant formula
4. Liquid glucagon formulation discovered for potential use in artificial pancreas systems
5. Maths formula leads researchers to source of pollution
6. Breast milk promotes a different gut flora growth than infant formulas
7. UC Riverside developing biofuel formulations for California
8. New, cost-cutting approach to formulating pest-killing fungi
9. Human eye inspires clog-free ink jet printer invented by MU researcher
10. Beyond the microscope: Identifying specific cancers using molecular analysis
11. Nature: Microscope looks into cells of living fish
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... one of seven institutions in the country selected ... receive this year,s BEST Award a $2 ... university,s most promising biomedical sciences graduate trainees to ... that they have traditionally taken. , The award ... for Biomedical Scientists (iJOBs) program. It includes courses, ...
(Date:9/22/2014)... of 2,819 people have occurred in the wake of ... the Eldorado National Forest. The King Fire is ... the American River Canyon, Silver Creek Canyon, and the ... The fire has crossed into Placer County and burned ... National Forest. The anticipated spread is expected to be ...
(Date:9/21/2014)... Nations General Assembly events focussed on ways to save ... Grand Challenges Canada, funded by the Government of Canada, ... ideas to address this challenge. , The novel approaches ... mothers working in garment factories to express, pasteurize and ... absenteeism due to child illnesses, and lowering baby formula ...
Breaking Biology News(10 mins):Rutgers receives $2 million grant to prepare biomedical students for roles in industry 2Rutgers receives $2 million grant to prepare biomedical students for roles in industry 3Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 2Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 3Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 4Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 5Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 6Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 7Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 8Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 9Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 10Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 11Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 12Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 13Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 14Canada funds 22 innovative projects to help save 'Every Woman, Every Child' 15
... Jolla--Dr. Fred Gage, a professor in the Salk Institute ... John Adler Chair for Research on Age-Related Neurodegenerative Diseases, ... National Institutes of Health (NIH) Director,s Transformative Research Projects ... throughout the country and will be supported with a ...
... 28 Researchers at the John G. Rangos Sr. ... and the University of Pittsburgh School of Medicine have ... management of insulin and new glucose production, which could ... published online this week in Diabetes , a ...
... Rome, Italy The International Council for ... has established a major 10-year initiative which aims ... change for sustainability. This new international collaboration effort, ... coordination for science to respond to the most ...
Cached Biology News:Pitt team identifies key protein causing excess liver production of glucose in diabetes 2Research solutions for sustainability in a rapidly changing world 2
(Date:9/22/2014)... electrical engineering researchers have developed a unique nanoscale ... transportation of light. The discovery could have major ... devices for computation and communication. , The research ... engineering assistant professor Mo Li and his graduate ... will appear in the October issue of ...
(Date:9/22/2014)... Rhinebeck, NY (PRWEB) September 22, 2014 ... commitment helping those in pain end their suffering, restoring ... sustainable healthcare model. This is only possible because of ... relief and healing cream technology a reality. , ... in Rhinebeck, NY, by Lou Paradise (president, chief of ...
(Date:9/22/2014)... TORONTO , Sept. 22, 2014 /PRNewswire/ ... today announced that it has entered into a ... which UHN,s Centre for Molecular Design and Preformulations ... project.  The goal of the project is to ... Company,s proprietary buccal insulin spray product, thereby reducing ...
(Date:9/22/2014)... 22, 2014 METTLER TOLEDO is ... pallet measuring device CNS110 ScanTape™ . Replacing ... entry, offering greater ease and accuracy for transport ... can significantly enhance productivity—an important benefit for load ... volume equals profits. , Usable at any ...
Breaking Biology Technology:Engineers show light can play seesaw at the nanoscale 2Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 2Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 3Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 4Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 5Topical BioMedics (Topricin) Celebrates 20 Years of Providing Hope and Quality of Life...As Topricin Is Declared “The 21st Century Standard of Care for Pain Management” 6Generex Collaborates with University Health Network for Buccal Insulin Project 2Generex Collaborates with University Health Network for Buccal Insulin Project 3Generex Collaborates with University Health Network for Buccal Insulin Project 4ScanTape™ Handheld Dimensioner Increases Processing Volume 2
... could be illegal , ,While Republican leaders in ... Gov. Jim Doyles Grow Wisconsin program, Sen. Ted Kanavas ... issue with the provisions for the state-funded venture capital ... proposed use of funds from the Patients Compensation Fund ...
... Your 4 year old has stomach pains, and you drive to ... personal medical information including her medical history and your billing and ... to remember if you told the person at the front desk ... triage nurse does not see bleeding or an apparent emergency. Next ...
... great perk to traveling getting to see what the rest ... vacationing with the family for spring break, content to play a ... confronted with a barrage of hype over Arizonas biotech efforts. While ... the buzz over Arizonas efforts to invest in technology. , ...
Cached Biology Technology:Republicans criticize Doyles growth package 2Republicans criticize Doyles growth package 3Republicans criticize Doyles growth package 4Childrens Medical Hospital of Wisconsin Goes Digital 2Childrens Medical Hospital of Wisconsin Goes Digital 3Childrens Medical Hospital of Wisconsin Goes Digital 4Commentary: Is our Biosphere too cheesy? 2
... cDNA Purification Kit is designed to purify double-stranded ... cDNA synthesis and PCR. The process is simple ... to 3 g can be efficiently purified and ... 1) DNA is bound to the Microfilter Cartridge ...
Normal donkey serum collected from healthy normal donkeys....
Whole blood is collected from canines (any breed, either sex), refrigerated within 6 hours, processed within 24 hours and frozen at -20C....
... Error-free cloning of BAC (100+kb), fosmid (40kb), ... insert stability than any othe BAC vector. ... high yields and easy recombinant DNA purification. ... transcription-free (pSMART VC) vectors for the highest ...
Biology Products: