Navigation Links
New coronavirus has many potential hosts, could pass from animals to humans repeatedly
Date:12/10/2012

The SARS epidemic of 2002-2003 was short-lived, but a novel type of human coronavirus that is alarming public health authorities can infect cells from humans and bats alike, a fact that could make the animals a continuing source of infection, according to a study to be published in in mBio, the online open-access journal of the American Society for Microbiology, on December 11. The new coronavirus, called hCoV-EMC, is blamed for five deaths and several other cases of severe disease originating in countries in the Middle East. According to the new results, hCoV-EMC uses a different receptor in the human body than the SARS virus, and can infect cells from a wide range of bat species and pigs, indicating there may be little to keep the virus from passing from animals to humans over and over again.

First identified in a patient in Saudi Arabia in June, nine laboratory-confirmed cases of hCoV-EMC infection have now been identified, five of whom have died. Although the virus does not apparently pass from person-to-person very readily, the case fatality rate and the fact that the source of the virus has not been identified have caused concern among global public health authorities. Cases of hCoV-EMC infection are marked by severe pneumonia and often by kidney failure.

"This virus is closely related to the SARS virus, and looking at the clinical picture, it causes the same pattern of disease," says Christian Drosten of the University of Bonn Medical Centre in German, a lead author of the study.

Given the similarities, Drosten and his colleagues wanted to know whether hCoV-EMC and SARS might use the same receptor, a sort of molecular "dock" on human cells that the virus latches onto to gain entry to the cell. The SARS receptor, called ACE2, is found mostly on pneumocytes deep within the human lung, so an individual must breathe in many, many SARS viruses for a sufficient number of them to reach this susceptible area and cause an infec
'/>"/>

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. New coronavirus related to viruses from bats
2. ALS TDI and Gladstone Institutes collaborate to discover potential ALS treatments
3. Fracking in Michigan: U-M researchers study potential impact on health, environment, economy
4. Potentially toxic flame retardants found in many US couches
5. Surface analysis techniques for advanced materials enhance Mazovias research potential
6. An international competition reaffirms the potential of bioinformatics in the diagnosis of disease
7. Scripps Research Institute team identifies a potential cause of Parkinsons disease
8. Researchers tap into CO2 storage potential of mine waste
9. Stem cell scientists discover potential way to expand cells for use with patients
10. King Richard III search in new phase after discovery has potential to rewrite history
11. New potential targets discovered for treating squamous cell lung cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2015)...  TAKE Solutions Ltd., a global business technology solutions ... Patent and Trademark Office (USPTO) for its "Method for ... Clinical Accelerators to reduce the time taken to standardize ... without the accelerators), thus reducing time to market. ... the heart of the patented Clinical Data Standardization Process ...
(Date:6/24/2015)... Calif. , June 24, 2015  Synaptics ... of human interface solutions, today announced that Sharp ... to provide secure authentication for its latest flagship ... reached more than 200 million shipments of its ... Sharp reinforces Synaptics, strength, scalability and leadership in ...
(Date:6/23/2015)... , June 23, 2015   MedNet ... that supports the entire spectrum of clinical research, ... ™ , the company,s intuitive, flexible ... awarded a Silver 2015 Stevie® Award by the ... Products & Services Website category.  The American Business ...
Breaking Biology News(10 mins):TAKE Solutions Awarded Patent By USPTO 2Synaptics Brings Natural ID Technology to Sharp's Newest Flagship Smartphone 2MedNet Solutions' iMedNet eClinical Wins Silver Stevie Award 2
... issue of BioScience includes a Special Section consisting ... by Louis J. Guillette, Jr., of the University of Florida. ... is as follows: Meeting the Challenges of Aquatic ... and Matthew L. Rise. , As a model organism for ...
... A study describing how cells within blood vessel walls move ... genomics that the proteins driving cell behavior are doing ... group them according to a few discrete functions. But ... shown that distinct groups of proteins each control one of ...
... violin to produce strong, elegant notes, researchers at The ... of the body,s killer immune system cells which they ... in superb infection- and disease-fighting condition. In a ... , the researchers describe their discovery of seven different ...
Cached Biology News:BioScience tip sheet, December 2008 2Cell movements totally modular, Stanford study shows 2Cell movements totally modular, Stanford study shows 3Wistar scientists find key to keeping killer T cells in prime shape for fighting infection, cancer 2Wistar scientists find key to keeping killer T cells in prime shape for fighting infection, cancer 3
(Date:7/6/2015)... ... July 06, 2015 , ... ... (WPI), offers new insights into how virulent fungi adapt through genetic modifications to ... how that battle leaves them temporarily weakened. These insights may provide clues to ...
(Date:7/6/2015)... 6, 2015  Approximately 1% of the population inherits ... chromosomes. These individuals are three times more likely to ... one of the nation,s leading medical journals by researchers ... Photo - http://photos.prnewswire.com/prnh/20150706/230685 ... causes roseola (also known as "sixth disease") and occasional ...
(Date:7/6/2015)... ... July 06, 2015 , ... Discovery of new biomarkers ... key drivers of the global molecular diagnostics market. BCC Research reveals in its ... new companion diagnostic tests will increase demand for inexpensive and accurate tests for ...
(Date:7/6/2015)... , July 6, 2015  Viveve Medical, Inc. ("Viveve") (OTCQB: ... Patricia Scheller , Viveve,s Chief Executive Officer, and ... at VirtualInvestorConferences.com on July 9, 2015. , , ... , , , , TIME:     , , ... , , , http://tinyurl.com/viveve   , ...
Breaking Biology Technology:Worcester Polytechnic Institute Co-directs Study That Provides New Insights into the Genetics of Drug-Resistant Fungal Infections 2Worcester Polytechnic Institute Co-directs Study That Provides New Insights into the Genetics of Drug-Resistant Fungal Infections 3Worcester Polytechnic Institute Co-directs Study That Provides New Insights into the Genetics of Drug-Resistant Fungal Infections 4Inherited Herpes Virus Increases the Risk of Angina Reports HHV-6 Foundation 2Inherited Herpes Virus Increases the Risk of Angina Reports HHV-6 Foundation 3Demand for Personalized Medicine, Innovative Molecular Diagnostic Tests Spurring Big Growth, According to BCC Research 2Demand for Personalized Medicine, Innovative Molecular Diagnostic Tests Spurring Big Growth, According to BCC Research 3Viveve to Webcast Live at VirtualInvestorConferences.com 2Viveve to Webcast Live at VirtualInvestorConferences.com 3
... across the developing world could reduce the environmental impact ... India, writing today in the Inderscience publication, International Journal ... in the developing world are encouraged to compost our ... compost bin and not all of us are willing ...
... sustainable solar energy by imitating nature. Nanotechnology researchers like ... nanoscale materials that mimic the architecture of grass and ... , A new podcast looks at how Dr. Lewis ... tiny nanoparticles into simple, inexpensive everyday products like house ...
... Lee Biosolutions, Inc, (http://www.leebio.com ) announces the ... human renin from human kidney. Human Renin ... blood pressure,and electrolyte homeostasis and therefore is of ... renin are of importance for the,development of hypertension ...
Cached Biology Technology:Landfill mining reduces environmental impact of growing waste 2
... The Neural Stem Cell Expansion Kit - Neurosphere ... neural stem cell expansion as neurospheres in ... specially formulated N-2 Plus Media Supplement, which has ... K.K. et al . (1996) Genes & ...
Request Info...
... a preparation of deoxyribonuclease I that ... produce 3-hydroxyl oligonucleotides. This preparation is ... maintaining the integrity of RNA is ... use with the Core Footprinting System ...
... catalyzes the template-directed polymerization of nucleotides into ... Polymerase I possesses a 3?5 exonuclease activity ... rate during DNA replication, and also contains ... enzyme to replace nucleotides in the growing ...
Biology Products: