Navigation Links
New cell division mechanism discovered
Date:10/28/2008

A novel cell division mechanism has been discovered in a microorganism that thrives in hot acid. The finding may also result in insights into key processes in human cells, and in a better understanding of the main evolutionary lineages of life on Earth. The study is published today in the online version the American National Academy of Sciences, PNAS.

The research group at the Department of Molecular Evolution at Uppsala University has identified a completely cell division machinery. The discovery was made in Sulfolobus acidocaldarius, a microorganism belonging to the third domain of life, the Archaea, which originally was isolated from a hot spring in Yellowstone national park in Wyoming, USA. Because of the extreme conditions, in which the cells grow optimally in acid at 80C, the organism is of interest for a wide range of issues.

- They represent exciting model systems in theories for how life once may have originated in hot environments on early Earth, as well as in the search for life in extreme environments on other planets, Professor Rolf Bernander explains. He is the scientist behind the study, together with colleagues Ann-Christin Linds, Erik Karlsson, Maria Lindgren and Thijs Ettema.

The researchers have identified three genes that are activated just prior to cell division. The protein products from these genes form a sharp band in the middle of the cell, between newly segregated chromosomes, and then gradually constrict the cell such that two new daughter cells are formed.

- This is the first time in decades that a novel cell division mechanism has been discovered, and the gene products display no similarity to previously known division proteins, Rolf Bernander says.

Two of the three proteins are instead related to eukaryotic so-called ESCRT- proteins, which play important roles in vesicle formation during intracellular transport processes, and which also have been implicated in virus budding, including HIV, from the cell surface. The results are, thus, important not only for an increased understanding of the cell biology of archaea and extremophiles, but also for key cellular processes in human and other higher organisms, and for issues related to the origin and evolutionary history of these processes.


'/>"/>

Contact: Rolf Bernander
rolf.bernander@ebc.uu.se
46-018-471-4698
Uppsala University
Source:Eurekalert

Related biology news :

1. Rong Li Lab probes mechanism of asymmetry in meiotic cell division
2. LIAI launches new division to look at novel approaches to heart disease and inflammation
3. Death, division or cancer? Newly discovered checkpoint process holds the line in cell division
4. A study reveals how cells communicate to activate the cell division machinery
5. A unique arrangement for egg cell division
6. Scientists unveil mechanism for up and down in plants
7. Newly-discovered mechanism can explain the Beckwith-Wiedemann syndrome
8. Conaway Lab identifies novel mechanism for regulation of gene expression
9. New mechanism for cardiac arrhythmia discovered
10. Novel anti-cancer mechanism found in long-lived rodents
11. Oxidative stress: Mechanism of cell death clarified
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... first robotic gym for the rehabilitation and functional motor sense evaluation of ... Italy . The first 30 robots will be available from June ... . The technology was developed and patented at the IIT laboratories and ... thanks to a 10 million euro investment from entrepreneur Sergio Dompè. ... ...
(Date:4/24/2017)... , April 24, 2017 Janice ... partner with  Identity Strategy Partners, LLP (IdSP) , ... or without President Trump,s March 6, 2017 ... Entry , refugee vetting can be instilled with greater ... (Right now, all refugee applications are suspended by ...
(Date:4/13/2017)... Calif. , April 13, 2017 UBM,s ... York will feature emerging and evolving technology ... Both Innovation Summits will run alongside the expo portion ... speaker sessions, panels and demonstrations focused on trending topics ... largest advanced design and manufacturing event will take place ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... ... ... wash is a basic first aid supply for any work environment, but most personal eye ... first if a dangerous substance enters both eyes? It’s one less decision, and likely quicker ... eye piece. , “Whether its dirt and debris, or an acid or alkali, getting anything ...
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/10/2017)... , ... October 10, 2017 , ... San Diego-based team ... its corporate rebranding initiative announced today. The bold new look is part of ... the company moves into a significant growth period. , It will also expand its ...
(Date:10/10/2017)... -- International research firm Parks Associates announced today that ... TMA 2017 Annual Meeting , October 11 in Scottsdale, Arizona ... market and how smart safety and security products impact the competitive landscape. ... Parks Associates: Smart Home Devices: Main Purchase ... "The residential security market has experienced continued growth, ...
Breaking Biology Technology: