Navigation Links
New cell division mechanism discovered
Date:10/28/2008

A novel cell division mechanism has been discovered in a microorganism that thrives in hot acid. The finding may also result in insights into key processes in human cells, and in a better understanding of the main evolutionary lineages of life on Earth. The study is published today in the online version the American National Academy of Sciences, PNAS.

The research group at the Department of Molecular Evolution at Uppsala University has identified a completely cell division machinery. The discovery was made in Sulfolobus acidocaldarius, a microorganism belonging to the third domain of life, the Archaea, which originally was isolated from a hot spring in Yellowstone national park in Wyoming, USA. Because of the extreme conditions, in which the cells grow optimally in acid at 80C, the organism is of interest for a wide range of issues.

- They represent exciting model systems in theories for how life once may have originated in hot environments on early Earth, as well as in the search for life in extreme environments on other planets, Professor Rolf Bernander explains. He is the scientist behind the study, together with colleagues Ann-Christin Linds, Erik Karlsson, Maria Lindgren and Thijs Ettema.

The researchers have identified three genes that are activated just prior to cell division. The protein products from these genes form a sharp band in the middle of the cell, between newly segregated chromosomes, and then gradually constrict the cell such that two new daughter cells are formed.

- This is the first time in decades that a novel cell division mechanism has been discovered, and the gene products display no similarity to previously known division proteins, Rolf Bernander says.

Two of the three proteins are instead related to eukaryotic so-called ESCRT- proteins, which play important roles in vesicle formation during intracellular transport processes, and which also have been implicated in virus budding, including HIV, from the cell surface. The results are, thus, important not only for an increased understanding of the cell biology of archaea and extremophiles, but also for key cellular processes in human and other higher organisms, and for issues related to the origin and evolutionary history of these processes.


'/>"/>

Contact: Rolf Bernander
rolf.bernander@ebc.uu.se
46-018-471-4698
Uppsala University
Source:Eurekalert

Related biology news :

1. Rong Li Lab probes mechanism of asymmetry in meiotic cell division
2. LIAI launches new division to look at novel approaches to heart disease and inflammation
3. Death, division or cancer? Newly discovered checkpoint process holds the line in cell division
4. A study reveals how cells communicate to activate the cell division machinery
5. A unique arrangement for egg cell division
6. Scientists unveil mechanism for up and down in plants
7. Newly-discovered mechanism can explain the Beckwith-Wiedemann syndrome
8. Conaway Lab identifies novel mechanism for regulation of gene expression
9. New mechanism for cardiac arrhythmia discovered
10. Novel anti-cancer mechanism found in long-lived rodents
11. Oxidative stress: Mechanism of cell death clarified
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/2/2016)... MOUNTAIN VIEW, Calif. , Feb. 2, 2016 ... diabetic retinopathy market, Frost & Sullivan recognizes US-based ... North America Frost & Sullivan Award for New ... technology provider in North America ... standard in the rapidly growing diabetic retinopathy market. ...
(Date:1/27/2016)... 2016  Rite Track, Inc. a leading semiconductor equipment ... Chester, Ohio announced today the acquisition of PLUS ... in Austin, Texas , will significantly ... modifications, installations and technical support offerings for TEL Track ... commented, "PLUS has provided world class service including refurbishment, ...
(Date:1/21/2016)... India , January 21, 2016 ... According to a new market research report "Emotion Detection ... and Others), Software Tools (Facial Expression, Voice Recognition ... Regions - Global forecast to 2020", published by ... is expected to reach USD 22.65 Billion by ...
Breaking Biology News(10 mins):
(Date:2/10/2016)...  Matchbook, Inc., a company specializing in procurement ... announced today the appointment of Jim Shuman ... nearly 25 years of experience in supply chain, ... two decades in executive level roles as the ... and, most recently headed global logistics and procurement ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... ... expansion to their comprehensive training and support program, Sonalink™ remote monitoring. The inaugural ... procedures performed on Friday, February 5th, connecting Dr. Samuel Peretsman to a HIFU ...
(Date:2/10/2016)... Jolla CA (PRWEB) , ... February 10, 2016 , ... ... new agents for the treatment of Alzheimer’s disease, announced today it has been selected ... February 18th at the Breakers in Palm Beach, Florida. The purpose of the ...
(Date:2/9/2016)... ... February 08, 2016 , ... ... Location: Baruch S. Blumberg Institute at the Pennsylvania Biotechnology Center of Bucks County, ... and The Commonwealth Medical College (TCMC) will hold an open house for participants ...
Breaking Biology Technology: