Navigation Links
New York University scientists discover possible treatment to reduce scarring
Date:7/6/2012

Bethesda, MDWhether from surgery or battle wounds, ugly scars can affect body and mind. Now a new research report appearing online in the FASEB Journal offers a new strategy to reduce or eliminate scars on the skin. Specifically, scientists from NYU describe how agents that block receptors for adenosine (a molecule generated from ATP which is used by the body to provide energy to muscles) can be applied topically to healing wounds to reduce scar size, yielding skin that feels more like the original, unscarred skin.

"Scars can be disfiguring and, if extensive enough, can lead to diminished function and quality of life," said Bruce N. Cronstein, M.D., a researcher involved in the work from the Division of Translational Medicine in the Department of Medicine at New York University School of Medicine in New York, NY. "We hope that our findings may lead to new agents that diminish scarring and disfigurement following burns, wounds, or even illnesses that destroy skin and lead to a better quality of life for victims of these traumas."

When the skin or other tissues are wounded, ATP leaks from the damaged cells and is then converted to adenosine which promotes healing. Scars form when adenosine continues to be produced at the wound site after the injury is healed, leading to larger, thicker scars than what may have otherwise been there. To study the possibility of reducing scar sizes, Cronstein and colleagues studied wounds on the backs of mice. After the wound closed, the adenosine A2A receptor antagonist was applied. They found that the adenosine A2A receptor agonist prevented excessive scar tissue in the treated mice.

"The vast majority of scars are hardly noticeable, if they can be seen at all," said Gerald Weissmann, M.D., Editor-in-Chief of the FASEB Journal, "but for some, scars can severely disfigure not only the body, but the mind. Finding ways to prevent scarring after wounds or surgery has the potential to improve the quality of life for those who suffer the slings and arrows of outrageous fortune, now and for generations to come."


'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Related biology news :

1. Royal Astronomical Society and Oxford University Press partnership announced
2. Mainz University coordinates new EU project on the origins of human settlement
3. University of Tennessee professor receives funding for clean coal research
4. University of North Texas Health Science Center Advances Forensic Research by Investing in Semiconductor DNA Sequencing Technology
5. IOC recognizes University of Calgary Sports Injury Research Prevention Centre
6. Loss of biodiversity increasingly threatens human well-being: UBC, University of Michigan research
7. NIH supporting Arizona State University research to help in fight against kidney disease
8. University of Tennessee anthropologists find American heads are getting larger
9. Wells Fargo fosters environmental conservation through University of Miamis RJD program
10. University of Leicester study finds low agreeableness linked to a preference for aggressive dogs
11. University of Hawaii Cancer Center researchers create new anti-cancer drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/22/2016)... -- The American College of Medical Genetics and Genomics was once ... one of the fastest-growing trade shows during the Fastest 50 ... Las Vegas . Winners ... each of the following categories: net square feet of paid ... The 2015 ACMG Annual Meeting was ranked 23 out of ...
(Date:6/20/2016)... June 20, 2016 Securus Technologies, a ... solutions for public safety, investigation, corrections and monitoring ... involved, it has secured the final acceptance by ... for Managed Access Systems (MAS) installed. Furthermore, Securus ... to be installed by October, 2016. MAS distinguishes ...
(Date:6/9/2016)... June 9, 2016 Paris ... Teleste,s video security solution to ensure the safety of people ... during the major tournament Teleste, an international ... and services, announced today that its video security solution will ... to back up public safety across the country. The system ...
Breaking Biology News(10 mins):
(Date:11/30/2016)... - Portage Biotech Inc. ("Portage" or "the Company") (OTC: ... announce the formation of EyGen, Ltd. a new ... through proof of concept. EyGen,s lead asset is ... Limited and being developed for topical ophthalmic delivery ... diseases. This agent has the potential to become ...
(Date:11/30/2016)... 30, 2016  The Allen Institute for Cell ... first publicly available collection of gene edited, fluorescently ... key cellular structures with unprecedented clarity. Distributed through ... tools are a crucial first step toward visualizing ... what makes human cells healthy and what goes ...
(Date:11/30/2016)... Nov. 30, 2016  Tempus, a technology company ... and Penn,s Abramson Cancer Center have partnered to ... response to immunotherapy treatment based on next generation ... part of a research collaboration, Tempus will provide ... cancer patient data to Penn. Utilizing next-generation sequencing, ...
(Date:11/30/2016)... 30. November 2016   Merck , ... die Unterzeichnung einer Reihe von Vereinbarungen mit ... Evotec AG Screeningleistungen für Mercks Palette genetischer ... Zugriff auf diese Bibliotheken in Kombination mit ... schnelleren Weg zur Ermittlung und Erforschung neuer ...
Breaking Biology Technology: