Navigation Links
New X-ray method shows how frog embryos could help thwart disease
Date:5/17/2013

LEMONT, Ill. An international team of scientists using a new X-ray method recorded the internal structure and cell movement inside a living frog embryo in greater detail than ever before.

This result showcases a new method to advance biological research and the search for new treatments for genetic diseases.

Scientists at Northwestern University and the Karlsruher Institut fr Technologie in Germany, in collaboration with the Advanced Photon Source at the U.S. Department of Energy's Argonne National Laboratory, released the most precise depiction ever of the embryonic development of African clawed frogs, one of the most frequently studied model organisms in biology.

The results titled "X-ray phase-contrast in vivo microtomography probes new aspects of Xenopus gastrulation" were published May 16 in the journal Nature.

The team X-rayed an embryo during gastrulation, the period when its hundreds of cells start to organize into differentiated tissues that eventually form the nervous system, muscles and internal organs. Studies of African clawed frog embryos can provide clues to the evolution of vertebrates and how human genes turn on or off to create diseases.

Until now, however, it has been difficult to study these embryos. Classical absorption imaging requires a contrast agent and large X-ray dose that can harm living organisms. Researchers from the German synchrotron ANKA proposed a new method of nondestructive analysis using X-ray diffraction. The work was done at the APS outside Chicago because the APS's high-energy X-rays were required to prevent blurring of the image and damage to the sensitive embryos.

"To obtain the best possible results, a highly coherent high-energy X-ray source with high flux is necessary," said Xianghui Xiao, a scientist at the APS who collaborated on the work. "The APS is one of only a few X-ray lightsources in the world with this capability. The upgrade of the APS will further improve our ability to
'/>"/>

Contact: Jared Sagoff
jsagoff@anl.gov
630-252-5549
DOE/Argonne National Laboratory
Source:Eurekalert

Page: 1 2

Related biology news :

1. Dental X-rays linked to common brain tumor
2. Stanford-SLAC team uses X-ray imaging to observe running batteries in action
3. Speed and power of X-ray laser helps unlock molecular mysteries
4. Low-cost carbon capture gets X-rayed
5. X-rays reveal the self-defence mechanisms of bacteria
6. Study provides recipe for supercharging atoms with X-ray laser
7. X-ray laser helps slay parasite that causes sleeping sickness
8. Scientists reassemble the backbone of life with a particle acceleratorynchrotron X-rays
9. X-rays reveal uptake of nanoparticles by soya bean crops
10. Improved X-ray microscopic imaging
11. A dual look at photosystem II using the worlds most powerful X-ray laser
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/22/2014)... Analyzing thousands of breeding bird surveys sent in ... Canada over 35 years, wildlife researchers report that most ... northward or toward higher elevation in response to climate ... means that most previous studies of potential climate change ... or the other have likely underestimated the effects of ...
(Date:4/22/2014)... effects of temperature and precipitation on the global distribution ... of climate research, the UV-B radiation, is often neglected. ... colleagues from the Universities in Olomouc (Czechia), Halle and ... space agency in such a way that they can ... on organisms. , The basic input data were provided ...
(Date:4/22/2014)... your age" is another way of asking him or ... bring improvements. Certain cells of the immune system tend ... to illness. Because these cells are known to misbehave ... microgravity on immune cells to better understand how our ... the National Institute on Aging, part of the National ...
Breaking Biology News(10 mins):Wildlife response to climate change is likely underestimated, experts warn 2UV-radiation data to help ecological research 2For an immune cell, microgravity mimics aging 2For an immune cell, microgravity mimics aging 3For an immune cell, microgravity mimics aging 4For an immune cell, microgravity mimics aging 5
... , WEST LAFAYETTE, Ind. - Scientists could take greater ... of advanced techniques used to understand the mechanisms that ... former Purdue University researchers say. In a perspective ... Purdue assistant professor of genetics, and Ivan Baxter, a ...
... could make more tomatoes taste like heirlooms, reports an international ... scientist. The finding, which will be reported in the ... significant implications for the U.S. tomato industry, which annually harvests ... and fresh-market sales. "This information about the gene responsible ...
... big boss proteins that switch on broad developmental ... regulators of muscle development or fat metabolism. One ... protein, takes charge following a cellular crisis known ... by the accumulation of misfolded and aggregated proteins. ...
Cached Biology News:Adoption of advanced techniques could propel crop improvement 2Discovery may lead to new tomato varieties with vintage flavor and quality 2Forty's a crowd 2Forty's a crowd 3Forty's a crowd 4
(Date:1/15/2014)... Pittsburgh, PA (PRWEB) January 15, 2014 The ... Company, publisher of Food Safety Tech , an e-Journal ... has signed an agreement for the second year for the ... with Pittcon 2014. The partnership provides that the registration fee ...
(Date:1/15/2014)... Westlake Village, Calif. (PRWEB) January 15, 2014 ... cancer treatment and management through the genomic analysis of ... will offer Therapy Finder™, a web-based cancer decision support ... a reporting option with Cynvenio’s ClearID™ genomic test, Therapy ...
(Date:1/15/2014)... 15, 2014 This webinar will focus ... clinical safety assessment in biosimilars. , Regulatory frameworks are ... drug development, however the complex nature of biopharmaceuticals makes ... and efficacy extremely challenging. Based on the specific aspects ...
(Date:1/15/2014)... Reston, VA (PRWEB) January 15, 2014 ... education have continued their sponsorship of an annual competition ... interest in, and access to, innovative STEM study. The ... , TEAMS: Tests of Engineering Aptitude, Mathematics, and ...
Breaking Biology Technology:Pittcon Announces Second Year Partnership With Food Safety Tech 2Pittcon Announces Second Year Partnership With Food Safety Tech 3Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 3Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5
... April 24, 2008 / b3c newswire / - ... are working on a project to synthesize a gene ... statistically expected and controlled ratio at preselected positions within ... core technology, Slonomics™, a unique DNA engineering platform using ...
... N.C. -- Duke University chemists have found a way ... thick in very large numbers, removing a major roadblock ... These single-walled carbon nanotubes also follow parallel paths as ... potentially impede electronic performance, said Duke associate chemistry professor ...
... Sangamo,BioSciences, Inc. (Nasdaq: SGMO ) today announced ... results on Wednesday, April 30,2008, after the market closes. ... at 2:00 p.m. PT, which will be open to ... the company will review,the financial results and discuss other ...
Cached Biology Technology:Sloning and the Kornberg group at Stanford University starting evaluation project regarding the synthesis of a Statistically Randomized Gene Library 2Nanotubes grown straight in large numbers 2Nanotubes grown straight in large numbers 3Sangamo BioSciences Announces First Quarter Conference Call and Webcast 2Sangamo BioSciences Announces First Quarter Conference Call and Webcast 3
Immunochemistry 1 & 2...
...
Hucal Agx Antigen Expression Service Specificity: Hucal Agx ...
MHC. Sections include: the isolation and functional properties of antigen-presenting cells analysis of MHC class II endocytosis and peptide turnover analysis of signalling via MHC class II molecu...
Biology Products: