Navigation Links
New Keck award spurs research for low-cost, mass measurements
Date:8/24/2011

Mass is a fundamental physical property common to all substances. Accurate measurements of mass are critical for a broad range of investigations, but at the scale of single molecules, such sensitive detections are notoriously tricky, laborious and expensive.

Nongjian (NJ) Tao and his colleagues at Arizona State University's Biodesign Institute are developing a clever way to perform useful analyses of single molecules, including precise measurements of mass as well as of the binding affinity of these particles. The technique will find diverse applications in such areas as pharmaceutical drug screening, analysis of single cells, food safety, environmental science, biomedical research and clinical diagnosis.

A recent 4-year, $1 million grant from the W. M. Keck Foundation will enable Tao's group to build, test and further refine the mass detection method, which makes use of molecular oscillators. Oscillators are essential components found in everyday devices such as clocks, computers and radios. They also play a vital role in biological systems, involved in regulatory networks and rhythmic patterns of activity.

According to Tao, "the Keck grant provides us with a great opportunity to address how we can identify a single molecule based on precise measurement of its mass, and study its affinity properties without using labels. This capability will overcome the limitations of the current mass spectroscopy and immunoassay technologies for detection and functional analysis of molecules."

Until now, measurements of mass at the molecular scale have often been performed using elaborate and costly devices known as mass spectrometers, in which the mass to charge ratio of a molecule is detected after it has been ionized. The technique has been an enormous boon to science, allowing for detailed analysis of proteins, the identification of biomarkers for disease diagnosis, monitoring of environmental toxins, and chemical agent screening.<
'/>"/>

Contact: Joseph Caspermeyer
joseph.caspermeyer@asu.edu
Arizona State University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. NIH doles out $3M in new innovator awards to 2 UC San Diego faculty
2. Wistar Institute researcher receives New Innovator award from NIH
3. Stevens awarded $1M for advanced biofuels research
4. NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves
5. L-1 Identity Solutions Awarded New Massachusetts RMV Drivers License Contract Valued at an Estimated $32 Million
6. Entomological Society of America names 2008 award winners
7. 8 National Medals of Science awardees to be honored at gala, then the White House
8. BIO-keys(R) Law Enforcement Group Awarded $700,000 in New Contracts
9. Broad Institute awarded major grant to bolster epigenomics research
10. Entertainment Software Association Foundation awards grant to FAS for immune attack
11. Audience Selected as Silver Winner in This Years Wall Street Journal Technology Innovation Awards and Winner of the Semiconductors Category
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New Keck award spurs research for low-cost, mass measurements  
(Date:10/15/2014)... The Ebola virus is spreading rapidly and to an ... experienced in the past and the virus shows a ... been recorded before. For this reason, the German National ... of Science and Engineering, and the Union of the ... statement on the Ebola epidemic today. , In the ...
(Date:10/15/2014)... , Oct. 15, 2014   Neurotechnology ... today announced the availability of the VeriLook ... Surveillance 3.0 provides real-time biometric face identification using ... digital surveillance cameras. The new version not only ... differentiates people from objects while they are moving ...
(Date:10/14/2014)... fly genome for the first time, revealing robust immune ... thrives in pathogen-rich dung piles and garbage heaps. , ... Genome Biology , will increase understanding of house fly ... to resist insecticides, which could lead to novel control ... transmit more than 100 human and animal diseases, including ...
Breaking Biology News(10 mins):Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 3House fly genome reveals expanded immune system 2
... awarded two Clemson chemistry faculty nearly $1 million to ... McNeill and Ken Christensen will receive the $960,000 grant ... in live cells. The development of techniques for ... could use this technology to determine the bodys defenses ...
... Mo. Heart disease is the leading cause of ... quality and length of life for individuals with specific ... gene and/or stem cell therapy could help a variety ... have been unsure whether the heart could benefit from ...
... the superhero cure for viral infections, may be ... infections in immunocompromised patients, according to an article ... Fungal infections (mycoses) were once seen as exotic ... life-threatening in healthy patients, fungal infections are a ...
Cached Biology News:NIH recognizes Clemson nanotechnology for molecule tracking 2Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heart 2Gamma interferon could aid fight against fungal infections 2
(Date:10/22/2014)... , Oct. 22, 2014 Nuvilex, Inc. ... approximately 400 million people worldwide are living with diabetes, ... people by 2030.  The global market for diabetes treatments ... approximately 330,000 people worldwide died from pancreatic cancer.  Pancreatic ... due to cancer in the United States ...
(Date:10/20/2014)... , Oct. 20, 2014 Mapp Biopharmaceutical,s ... ZMapp™ antibody therapeutic to fight the Ebola outbreak ... and time-consuming the production of pharmaceuticals can be, ... publisher said that while some may be taken ... compound, those with industry knowledge are well aware ...
(Date:10/20/2014)... , October 20, 2014 , ... (GI) disorders and the delivery of care has revealed ... and worrying inequalities in the provision of healthcare services ... was commissioned by United European Gastroenterology (UEG), have been ... and public awareness of the burden of GI disorders ...
(Date:10/20/2014)... Rochelle, Virginia (PRWEB) October 20, 2014 ... of NDA Partners LLC, announced today that Ellen ... and legal support for the pharmaceutical industry, has ... and manager of its legal services practice. ... reports and expert witness and testimony, to top ...
Breaking Biology Technology:Nuvilex Brief Analyst Report: Thinking Outside the Box by BrokerBank Securities, Inc. 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 2Kalorama: ZMapp Highlights Need For Faster Biopharmaceutical Production 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5NDA Partners Appoints Ellen Teplitzky, JD as Director of its Legal Services Practice 2
... Capabilities ... & Team, CANTON, Mass. and BATON ROUGE, ... successful regenerative medicine,company, announced today the strategic acquisition ... develops "designer scaffolds" for the,purposes of regenerative medicine, ...
... RESEARCH TRIANGLE PARK, N.C., Feb. 25 ... tools for signal,transduction analysis, announced today that ... flagmanship technology, the FACTORIAL(TM). In,advance online publication ... colleagues describes a novel and remarkably consistent ...
... Feb. 25 Alexza,Pharmaceuticals, Inc. (Nasdaq: ... initiated,its first Phase 3 clinical trial with ... candidate being developed for the treatment of,acute ... disorder. Alexza,believes the novel, non-invasive nature and ...
Cached Biology Technology:Organogenesis, Inc. Announces Acquisition of NanoMatrix, Inc. 2Organogenesis, Inc. Announces Acquisition of NanoMatrix, Inc. 3Attagene's Breakthrough Transcription Factor Profiling Technology to be Described in Nature Methods 2Attagene's Breakthrough Transcription Factor Profiling Technology to be Described in Nature Methods 3Alexza Initiates First Phase 3 Clinical Trial for AZ-004 (Staccato(R) Loxapine) 2Alexza Initiates First Phase 3 Clinical Trial for AZ-004 (Staccato(R) Loxapine) 3Alexza Initiates First Phase 3 Clinical Trial for AZ-004 (Staccato(R) Loxapine) 4Alexza Initiates First Phase 3 Clinical Trial for AZ-004 (Staccato(R) Loxapine) 5
... Ease of Use : GeneTraffic ... software tool for biological research. GeneTraffic provides ... to validate your data prior to analysis. ... Quickly define your projects using the MIAME ...
... rigid macroporous hydrophilic media. The rigid polymer ... pressures, while the macroporous beads enhance access ... reduces nonspecific binding. Macro-Prep High Q support ... very high flow rates and resolution. It ...
... siTrio siRNA --- a cocktail of 3 ... of interestis our most popular product. The ... 75% knockdown of your target gene when ... for transfection and confirmation of optimal transfection ...
... IDS 25-Hydroxy Vitamin D kit is ... determination of 25-hydroxyvitamin D (25-OH D) ... serum or plasma. Our patented DIRECT ... solvent precipitation and centrifugation and therefore ...
Biology Products: