Navigation Links
New, less invasive genetic test greatly improves pregnancy rates in older women with poor prognosis
Date:6/29/2009

ing embryo than other alternatives, such as day-three biopsy, which take place during conventional screening strategies involving the use of the FISH technique. The removal of the polar bodies does not adversely affect the subsequent development of the embryo. Additionally, the results obtained after CGH analysis of polar bodies are not affected by the presence of chromosomal mosaicism (the presence of two populations of cells with different genotypes) and therefore may be more accurate than conventional methods based upon screening of cells removed from embryos.

The scientists examined 400 fertilised eggs generated by women with a very poor reproductive history and with an average age of 42 who were undergoing IVF because of being unable to conceive or to maintain a pregnancy. They found that more than half of all the eggs produced by these women had chromosomal abnormalities, and therefore the resulting embryos were also chromosomally abnormal. Some of the women had a tendency to produce eggs that were extremely abnormal and carried multiple chromosome errors. This could explain the poor reproductive history of these women, the scientists say.

"But where we could find fertilised eggs free of chromosomal abnormalities, the resulting embryos were also normal and their transfer to the mother led to pregnancies," said Dr. Fragouli. "Results suggest that the use of this technique will improve IVF success rates for poor prognosis patients. It is also likely to achieve a reduction in congenital abnormalities such as Down's syndrome, as well as a reduction in the frequency of spontaneous miscarriage."

The incidence of chromosomal abnormalities in human eggs is closely related to maternal age, and can affect more than 60% of all eggs in women over 40 years of age. Being able to select the right egg can not only lead to more successful IVF, but also enhance the use of single embryo transfer, especially in countries where embryo testing is forbidde
'/>"/>

Contact: Mary Rice
mary@mrcommunication.org
European Society for Human Reproduction and Embryology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Invasive Australian jellyfish sighted in Gulf of Mexico in summer 2007
2. New chemically-sensitive MRI scan may bypass some invasive diagnostic tests in next decade
3. U of MN researchers discover noninvasive diagnostic tool for brain diseases
4. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
5. Minimally invasive heart surgery research wins NIH award
6. Smithsonian identifies invasive crab species in Panama Canal expansion area
7. Smithsonian identifies invasive crab species in Panama Canal expansion area
8. Book on weeds and invasive plants discusses how to manage them using ecological approaches
9. A new baseline of invasive plants in Isabela
10. Team of scientists develops non-invasive method to track nerve-cell development in live human brain
11. Relationship between invasive plants, fire subject of new report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... especially the young, are highly sensitive to temperature and ... temperatures within a narrow range. Recently published research led ... School of Arts and Sciences, is the first to ... hive in process similar to how humans and other ... , "This study shows how workers effectively dissipate ...
(Date:7/23/2014)... analysis of Antarctic fur seals, alongside decades of ... effect of climate change on a population of ... the findings show that the seals have significantly ... that are associated with climate conditions. Despite a ... fitness is not passing down through generations, leaving ...
(Date:7/23/2014)... samples cultured from cystic fibrosis patients, scientists at the ... Institute have shown that a new CF drug counteracts ... , The finding, published today in the journal ... protein becomes unstable and loses its ability to function ... The research offers several insights into how novel CF ...
Breaking Biology News(10 mins):How honey bees stay cool 2Genetic study shows major impact of climate change on Antarctic fur seals 2Genetic study shows major impact of climate change on Antarctic fur seals 3UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 2UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 3UNC researchers find unsuspected characteristics of new CF drugs, offering potential paths to more effective therapies 4
... Whitehead Institute scientists report that the gene mutated ... syndrome also prevents activation of mTORC1, a critical nutrient-sensing ... is an unexpected finding, as some cancers keep this ... expansion. In the case of Birt-Hogg-Dub syndrome, the mutated ...
... of ZooKeys - no. 346 ... on its day of publication last Friday. This marks ... taxonomic names for animals. The innovative workflow was jointly ... and a U.S. National Science Foundation project to ...
... The Prime Minister of Malaysia today outlined his country,s ... development goals, saying they need to address the relief ... concerns. Prime Minister Najib Razak commended the Millennium ... eight objectives agreed by nations in 2000 for completion ...
Cached Biology News:Gene responsible for hereditary cancer syndrome found to disrupt critical growth-regulating pathway 2Next-generation global e-infrastructure for taxon names registry 2As world sets new development goals, Malaysia calls for poverty relief within green agenda 2As world sets new development goals, Malaysia calls for poverty relief within green agenda 3As world sets new development goals, Malaysia calls for poverty relief within green agenda 4
(Date:7/23/2014)... (PRWEB) July 23, 2014 a2z Inc. ... ChirpE Mobile App, AACC Pathfinder, in its 2014 ... AACC’s annual meeting is planned for July 29-31, 2014 ... place to be to connect with global leaders in ... management, and other areas of breaking science in laboratory ...
(Date:7/22/2014)... phylum so full of mean little creatures, the yellow-colored Ormia ... -- at least to crickets. Native to the southeastern U.S. ... sort of parasite. It swoops onto the back of a ... its wicked brood to invade, kill and consume the cricket ... possible without the fly,s ability to find a cricket -- ...
(Date:7/22/2014)... New York (PRWEB) July 22, 2014 ... world. The heat produced by controlled fission chain reaction ... This steam pressure is used to drive a power- ... approximately 19% of the world’s total electricity production. Nuclear ... to several under construction, planned and proposed nuclear reactor ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 Two new ... Board of Directors at its annual Shareholders Meeting on ... Information Officer of The PFM Group, and Stephen T. ... Center also announced the election of Michael A. DiPiano, ... Vice Chair and Richard P. Jaffe, Esq., of Duane ...
Breaking Biology Technology:AACC Enhances Attendee Experience at Its 2014 Annual Meeting & Clinical Lab Expo with a2z-Powered ChirpE Photo Booth and Mobile App 2AACC Enhances Attendee Experience at Its 2014 Annual Meeting & Clinical Lab Expo with a2z-Powered ChirpE Photo Booth and Mobile App 3Fly-inspired sound detector 2Fly-inspired sound detector 3Fly-inspired sound detector 4Nuclear Energy Market: Global Industry Analysis, Size, Share, Analysis, Growth and Forecast 2013 - 2019 2Nuclear Energy Market: Global Industry Analysis, Size, Share, Analysis, Growth and Forecast 2013 - 2019 3Two New Members Elected to University City Science Center Board of Directors 2Two New Members Elected to University City Science Center Board of Directors 3
... and Advice Shared Through Dynamic WikiAnswers Q&A ... ... In a show of support for National,Breast Cancer Awareness Month, Answers.com,s ... http://wiki.answers.com/Q/FAQ/2375 ), where breast cancer survivors,friends and family have gathered to ...
... NEW YORK, Oct. 22 SPO Medical Inc. ... microprocessor,technologies for use in portable monitoring devices, today announced ... sales milestone has,been achieved within three years of the ... of the 100,000 units sold include the patented technology ...
... Pharmacopeia,(Nasdaq: PCOP ), an innovator in the discovery ... Dr. Leslie J. Browne,President and Chief Executive Officer, will ... Renshaw 9th Annual Healthcare,Conference. The conference will be held ... Hotel in New York City. Dr. Browne,s presentation ...
Cached Biology Technology:Answers.com's WikiAnswers Supervisors Rallying for National Breast Cancer Awareness Month 2Answers.com's WikiAnswers Supervisors Rallying for National Breast Cancer Awareness Month 3SPO Medical Announces Major Sales Milestone 2SPO Medical Announces Major Sales Milestone 3Pharmacopeia to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference 2Pharmacopeia to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference 3Pharmacopeia to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference 4
... Synucleins are small, soluble proteins expressed ... tumors. The family includes three known proteins: ... The alpha and beta synuclein proteins are ... are seen mainly in presynaptic terminals. ...
NAK/TBK1 (CT) Affinity Purified Polyclonal Antibody...
This adapter allows the Thermo-Fast® 96 Semi-Skirted (AB-0900 and AB-0990) PCR plates to be used directly in the ABI PRISM® 3100 sequencer without the need for software changes....
... Finnpipette BioControl multichannel has ... as the single channel ... fits allseven multichannel and ... cone modules. Both pipettes ...
Biology Products: