Navigation Links
New, less invasive genetic test greatly improves pregnancy rates in older women with poor prognosis
Date:6/29/2009

Amsterdam, The Netherlands: A new test examining chromosomes in human eggs a few hours after fertilisation can identify those that are capable of forming a healthy baby, a researcher told the 25th annual conference of the European Society of Human Reproduction and Embryology today (Monday 29 June). Dr. Elpida Fragouli, from the Department of Obstetrics and Gynaecology, University of Oxford, UK, and Reprogenetics UK, said that her team's work had already enabled seven ongoing pregnancies in a group of older women with a history of multiple failed IVF attempts.

"Out of 35 patients who had embryo transfers after the test, we achieved a pregnancy rate of 20%, which is exceptional considering the extremely poor prognosis of the women involved." she said. "This represents a doubling of the usual pregnancy rate for women who fall into this category, which is otherwise, at best, under 10% and, at worst, zero. To date, we have two live births from this group, and all the other women who became pregnant have maintained their pregnancies. The study is continuing, and we believe that we will achieve more pregnancies with the help of this technology in the future."

The scientists used the Comparative Genomic Hybridisation (CGH) technique to count the chromosomes in each egg. Unlike conventional screening strategies, using the fluorescent in situ hybridisation (FISH) method, which allows less than half of the chromosomes of an embryonic cell to be examined, CGH enables the evaluation of the entire chromosome complement. CGH was used to examine the fertilised eggs by looking at polar bodies, tiny cells that are a by-product of egg development. The chromosomes of polar bodies provide an indication of whether the corresponding egg is normal or abnormal; if the polar bodies have the wrong number of chromosomes, so does the egg.

Looking at polar bodies is a less invasive way of obtaining information about the chromosome content of an egg and its result
'/>"/>

Contact: Mary Rice
mary@mrcommunication.org
European Society for Human Reproduction and Embryology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Invasive Australian jellyfish sighted in Gulf of Mexico in summer 2007
2. New chemically-sensitive MRI scan may bypass some invasive diagnostic tests in next decade
3. U of MN researchers discover noninvasive diagnostic tool for brain diseases
4. U of Minnesota researchers discover noninvasive diagnostic tool for brain diseases
5. Minimally invasive heart surgery research wins NIH award
6. Smithsonian identifies invasive crab species in Panama Canal expansion area
7. Smithsonian identifies invasive crab species in Panama Canal expansion area
8. Book on weeds and invasive plants discusses how to manage them using ecological approaches
9. A new baseline of invasive plants in Isabela
10. Team of scientists develops non-invasive method to track nerve-cell development in live human brain
11. Relationship between invasive plants, fire subject of new report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/6/2014)... - Insilico Medicine, Inc, a Baltimore-based bioinformatics company ... diseases announced a research collaboration with the international ... Inc (OTC: CSBR). , "There are many companies ... Champions Oncology,s TumorGraft technology is unique in a ... experimentally generating vast amounts of valuable data. Our ...
(Date:11/4/2014)... In nature, the right amount of death at the ... density, according to new research that could help in ... wildlife stocks. , In a paper in the journal ... University researcher and European colleagues conclude that the kind ... a loss of individuals, or mortality, depends on the ...
(Date:11/4/2014)... 4, 2014) – A majority of Madagascar,s 101 species ... have serious consequences for the rainforests they call home. ... positive impacts lemurs can have on rainforest tree populations, ... could have on the region,s rich biodiversity. , A ... eaten by lemurs. Lemurs in turn disperse the ...
Breaking Biology News(10 mins):Insilico Medicine, Inc announces research collaboration with Champions Oncology, Inc 2When less is more: Death in moderation boosts population density in nature 2Gardeners of Madagascar rainforest at risk 2Gardeners of Madagascar rainforest at risk 3
... Alternative energy is all the rage in major media headlines, ... to a study by researchers from Denmark and The Netherlands ... FASEB Journal, the brain, just like muscles, works harder ... glucose. Not only does this finding help explain why the ...
... Letters, Steve Brusatte, Professor Michael Benton, and colleagues ... not proliferate immediately after they originated, but that their ... by two mass extinctions. "The sheer size ... something special about these animals that preordained them for ...
... future of the gorgeously-decorated fish which throng Australia,s coral reefs ... tourism may well be written in their genes. Of ... are able to re-colonise regions of reef devastated by global ... corals move south, says Dr Line Bay of the ARC ...
Cached Biology News:Mass extinctions and the evolution of dinosaurs 2Fishy future written in the genes 2Fishy future written in the genes 3
(Date:11/23/2014)... Francis, WI (PRWEB) November 23, 2014 ... manufacturer and supplier of fine chemical ingredients to ... announced the launch of its new website, Apiscent.com. ... description of Apiscent Labs, clean design, easy navigation, ... that make Apiscent Labs stand out. ...
(Date:11/22/2014)... November 21, 2014 Prominent academics, ... will gather on December 3rd at Genetic Rx, ... series. GeneticRx will take place at the Joseph ... and will discuss the present and future of ... skipping, and gene editing—as well as the treatment ...
(Date:11/22/2014)... IL (PRWEB) November 21, 2014 On ... competitors at the 2014 Emerging Medical Technologies Summit in ... Innovator Awards. Widely regarded among Silicon Valley investors ... medical device innovation, the win also positions Briteseed ... MedTech Innovator competition in 2015 and compete with other ...
(Date:11/22/2014)... 2014  The element of surprise has been a ... strike without warning. Until now, epidemiologists had nothing to ... outbreak, resulting in suboptimal responses to both the H1N1 ... Photo - http://photos.prnewswire.com/prnh/20141121/160242 ... because virus gene structural changes have been found that ...
Breaking Biology Technology:Pioneering Academics and Key Industry Leaders to Discuss Rare Diseases and the Emergence of New Genetic Medicines at Genetic Rx on December 3rd 2Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 2Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 3Viruses' Advantage of Surprise is Lost 2
... Practice Statements Were Presented at the AUA Annual,Meeting ... and PLYMOUTH MEETING, Pennsylvania, May 21 /PRNewswire/,-- Galil ... that the,American Urological Association has introduced clinical guidelines ... state,that cryoablation is a treatment option for men ...
... 21 Still River Systems announces,the successful development ... as part of the development of its Monarch250(TM) ... Tesla and conclusively,demonstrates that cyclotrons at this high ... radiation therapy. By increasing the operating,magnetic field, Still ...
... 21 Prime Therapeutics (Prime), a,thought leader ... it has,received accreditation from the National Association ... Internet Pharmacy Practice,Sites(TM) (VIPPS(R)) Program., Prime ... NABP in response to,consumers, concerns regarding the ...
Cached Biology Technology:American Urological Association (AUA) Clinical Guidelines Recognizes Cryotherapy as Treatment Option for Prostate Cancer Patients 2American Urological Association (AUA) Clinical Guidelines Recognizes Cryotherapy as Treatment Option for Prostate Cancer Patients 3Still River Systems Announces Operation of the World's Highest Magnetic Field Cyclotron 2Prime Therapeutics Receives VIPPS Accreditation 2
... designed to speed up the PCR cloning process ... of sequence or type of polymerase used, are ... are difficult to clone by other PCR cloning ... for potentially detrimental proteins can be cloned and ...
Size & Applications: 20 ml Storage Temp.: -20C Shelf Life: 12 months ...
PCR System for increased fidelity, yield and length of PCR products. Amplifies targets up to 10 kb from human genomic DNA....
Immunogen: Heat inactivated bacterial cells of Salmonella enteriditis,paratyphi and typhimurium Storage: 4 C...
Biology Products: