Navigation Links
New $11 million center to speed production of new compounds for drug discovery
Date:10/20/2008

Scientists from three Chicago-area universities have joined forces to develop new ways of building state-of-the-art chemical libraries that will help identify new compounds for future drug development and basic biomedical research.

Scientists from the University of Chicago, Northwestern University and the University of Illinois at Chicago will establish the Chicago Tri-Institutional Center for Chemical Methods and Library Development with a $9.2 million grant from the National Institutes of Health. Furthermore, the Chicago Biomedical Consortium, which is funded by the Searle Funds at the Chicago Community Trust, has awarded a $2 million Lever grant to support the core infrastructure of the center and to make its resources available to the entire Chicago scientific community.

"In order to develop new drugs, you need to start with new compounds," said Center Director Sergey Kozmin, Associate Professor in Chemistry at the University of Chicago.

Kozmin's laboratory screens compounds specifically for their ability to kill cancer cells, but the chemical libraries that the Chicago Tri-Institutional Center produces will be readily available to many biology labs across the nation. The center also will broadly test for potential use against neurodegenerative disorders, infectious diseases and other therapeutic targets.

During the last two years, Kozmin's laboratory has used parallel organic synthesis, which enabled them to perform many reactions simultaneously, to build 3,000 new molecules in his search for anti-cancer compounds. Now he and his associates have the resources to build a facility next year in the Searle Chemistry Laboratory on the University of Chicago campus that will be able to synthesize new compounds 10 times as fast.

The new center's work will focus on the synthesis of what biologists call "small molecules," Kozmin said. "Compared to large proteins, organic molecules that become drugs are rather smal
'/>"/>

Contact: Steve Koppes
skoppes@uchicago.edu
773-702-8366
University of Chicago
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Missouri Botanical Garden mounts milestone 6 millionth herbarium specimen
2. FSU researchers discovery leads to $1.5 million grant, potential new treatment of liver fibrosis
3. L-1 Identity Solutions Awarded New Massachusetts RMV Drivers License Contract Valued at an Estimated $32 Million
4. L-1 Identity Solutions Receives $5.9 Million Drivers License Contract Expansion from the State of Mississippi
5. NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves
6. £2 million study to reveal workings of dementia genes
7. Almost 7 million pregnant in sub-Saharan Africa infected with hookworms; at risk of anaemia
8. CCNY receives $5 million NSF grant to establish center for nanostructure applications
9. Burnham researcher awarded $8 million grant
10. NIEHS invests $21.25 million to find environmental causes of Parkinsons disease
11. Cornell gets $10 million NSF grant to establish new sustainability institute
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
New $11 million center to speed production of new compounds for drug discovery
(Date:12/22/2014)... Holiday Season may be the brightest ever for the ... long anticipated floodgates for consumer biometrics may finally be ... tablets, and wearable mobile devices that incorporate biometrics will ... nearly 4.8 billion biometric devices by 2020.   ...
(Date:12/19/2014)... , Dec. 18, 2014   LaunchKey , the ... the post-password and Internet of Things era, today announced ... The venture round was led by Metamorphic Ventures with ... Venture Partners, VegasTechFund, and others.  LaunchKey has raised $4 ...
(Date:12/17/2014)... 2014 Valencell, a leader in performance biometric data ... industry leaders such as Intel, Jabra, Atlas, and Scosche ... products. These products will be showcased at CES 2015, ... . "Our partners choose PerformTek ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2
... (WSU) Laboratory for Atmospheric Research is leading a nationwide ... the distribution of natural gas. Beginning this month, ... Lamb will quantify methane emissions throughout local gas systems ... data to estimate a national methane emissions rate for ...
... the University of Michigan have identified a new potential ... alternative or complementary therapy to statins. Scientists ... Sciences Institute inhibited the action of a gene responsible ... of the liver to remove cholesterol from the blood ...
... animals are frequently observed scavenging on other animals whether it ... or a buzzard swooping down on a dead animal. However, ... difficult, and often overlooked in marine food web studies. , ... titled, " White sharks ( Carcharodon carcharias ) scavenging on ...
Cached Biology News:Methane emissions from natural gas local distribution focus of new study 2Methane emissions from natural gas local distribution focus of new study 3U-M researchers find new way to clear cholesterol from the blood 2Great white sharks 2
(Date:1/23/2015)... , Jan. 23, 2015  Array BioPharma Inc. (NASDAQ: ... a definitive agreement with Novartis Pharma AG to acquire ... in Phase 3 development.  This agreement is conditional on the ... (GSK) on April 22, 2014, which are expected to close ...
(Date:1/22/2015)... Jan. 22, 2015  Transwestern | RBJ today announces the firm ... space for Shire a leading biopharmaceutical company, at Two Ledgemont ... RBJ,s Robert Richards , president, and Brian Cohen ... the entire five-floor building at 95 Hayden Ave. ...
(Date:1/22/2015)... The laboratory information management systems market is a rapidly ... advancements due to factors such as rising pressure to ... systems, and increasing government support for adoption of HCIT ... in the market focus on technological advancements to further ...
(Date:1/22/2015)... zFlo Motion , a US leader in biomechanics ... from a new partner. STT-Systems has developed an ... years, with offerings in the optical-motion capture, 3D scanning, and ... measurement unit), iSen, is opening eyes around the world. With ...
Breaking Biology Technology:Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 2Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 3Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 4Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 5Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 6Array Announces Agreement To Acquire ENCORAFENIB (LGX818) 7Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 43D Motion Capture Just Got Easy 2
... March 13 Innocoll, Inc., a,privately-held biopharmaceutical ... of planned phase 2 clinical trials sponsored ... to investigate CollaRx(R),BUPIVACAINE SURGICAL IMPLANT for the ... Innocoll,s BUPIVACAINE SURGICAL IMPLANT is a biodegradable ...
... scientists worldwide gain new insight ... funding support for human brain, spinal cord and developing ... brain projects, ... it is undertaking three major projects designed to,accelerate brain, and spinal cord research, ...
... 93.3%; Full Year Net Income up 283.0%, SHANGHAI, ... WX ), the leading global pharmaceutical,biotechnology and medical ... its unaudited financial results for the,fourth quarter and full ... 2007 Highlights:, Compared to the fourth quarter 2006 ...
Cached Biology Technology:Innocoll Announces Dosing of First Patient in a Second US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain 2Innocoll Announces Dosing of First Patient in a Second US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain 3Innocoll Announces Dosing of First Patient in a Second US Phase 2 Clinical Trial to Investigate CollaRx(R) BUPIVACAINE SURGICAL IMPLANT for the Management of Post-operative Pain 4Allen Institute for Brain Science Launches Three New Landmark Atlas Projects Focusing on the Human Brain, Developing Brain and Spinal Cord 2Allen Institute for Brain Science Launches Three New Landmark Atlas Projects Focusing on the Human Brain, Developing Brain and Spinal Cord 3Allen Institute for Brain Science Launches Three New Landmark Atlas Projects Focusing on the Human Brain, Developing Brain and Spinal Cord 4Allen Institute for Brain Science Launches Three New Landmark Atlas Projects Focusing on the Human Brain, Developing Brain and Spinal Cord 5WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 2WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 3WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 4WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 5WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 6WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 7WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 8WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 9WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 10WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 11WuXi PharmaTech Announces Fourth Quarter and Full Year 2007 Results 12
... the popular precision current source, designed ... neural transport tracers such as horseradish ... into neural tissue, is now available ... used to make small lesions, and ...
... Thermostable dUTPase The thermostable ... high-fidelity PCR (using proofreading DNA polymerases). ... in PCR reactions and dNTP solutions. ... a proofreading DNA polymerase reaction can ...
... The FLUOstar OPTIMA is a ... built for life science labs in ... four different measurement principles: Fluorescence ... applications Time-Resolved Fluorescence including ...
... kit measures mitochondria intactness and detects ... potential. Features and Benefits: ... staining isolated mitochondria and for assaying ... the reagents required for the detection ...
Biology Products: