Navigation Links
NYSCF Fellow lead author on study that creates blood vessel cells from stem cells
Date:1/21/2010

NEW YORK, NY (January 21) - New York Stem Cell Foundation (NYSCF)-Druckenmiller Fellow, Daylon James, PhD, of Weill Cornell Medial College, is lead author on a study defining conditions for generating a plentiful supply of endothelial (vessel lining) cells that are suitable for therapeutic use. Dr. James and his colleagues created a human embryonic stem cell (hESC) "reporter" line that can be used to measure endothelial cell production and activity.

The study, Expansion and maintenance of human embryonic stem cellderived endothelial cells by TGFβ inhibition is Id1 dependent, was published in the online edition of Nature Biotechnology on January 17th, 2010, and will also appear in the journal's print edition. In addition to Dr. James, whose work is funded by NYSCF, contributors to the study also included NYSCF-Druckenmiller Fellows, Drs. Gabsang Lee and Marco Seandel.

Using the reporter line, Dr. James and his colleagues were able to monitor the emergence of endothelial cells in live cultures, and screen for small bioactive molecules that increased their yield. By this method, they were able to indentify a compound that robustly increased the amount of endothelial cells produced. This work establishes a standard methodology for generating functional endothelial cells from hESCs using conditions that are suited to clinical application. These cells can now be routinely and economically produced on scales that make pre-clinical assessment of their efficacy practical in large animal models of vascular disease.

"We are very proud of Dr. James. These findings bring us closer to having functional endothelial cells available for studying vascular disease," says Susan L. Solomon, NYSCF's founder and CEO.

As advancements in induced pluripotent stem (iPS) cell technology continue, hESC research like that of Dr. James is essential for the field of stem cell research. Embryonic stem cells are still the gold standard fo
'/>"/>

Contact: Ruth Jarmul
rjarmul@nyscf.org
212-787-4111
New York Stem Cell Foundation
Source:Eurekalert

Page: 1 2

Related biology news :

1. IGERT fellows to design biodevices using flexible electronics
2. ASPB announces Summer Undergraduate Research Fellowship 2007 recipients
3. UC Riverside biologist receives prestigious MacArthur Fellowship
4. Entomological Society of America recognizes 2007 fellows and honorary members
5. Damon Runyon Cancer Research Foundation awards prestigious fellowships to 17 top young investigators
6. Pew Institute for Ocean Science awards 5 fellowships in support of global marine conservation
7. 2008 Pew Fellowship in marine conservation awarded to UM Rosenstiels Dr. Andrew Baker
8. Dr. Andrew Constable awarded 2008 Pew Fellowship in marine conservation
9. 2008 Pew Fellowship in Marine Conservation awarded to Dr. Ussif Rashid Sumaila
10. 2008 Pew Fellowship in Marine Conservation awarded to Fan Meng; first Chinese fellow
11. 2008 Pew Fellowship in Marine Conservation awarded to Dr. Marie-Joëlle Rochet from IFREMER
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/13/2015)... , Feb. 13, 2015 ACT Genomics ... that aims to transform cancer genomic information into ... the company has raised US$ 8 million in the ... in Taipei, Taiwan , ACT ... ACTOnco™. With the aim to implement next generation ...
(Date:2/11/2015)... , February 11, 2015 ... report "Access Control Market by Product (Cards and Readers, ... Military and Defense, Government, Industrial, Healthcare, Education) and By ... by MarketsandMarkets, the Access Control Market is ... growing at a CAGR of 10.6% between ...
(Date:2/5/2015)... North Carolina , 5. Februar 2015 ... Jahr als spezialisiertes Logistikunternehmen und hat eine ... einzige klinische Logistikfirma (Clinical Logistics Organization – ... der neuen Kampagne lautet First , ... Foto: http://photos.prnewswire.com/prnh/20150205/173753 ...
Breaking Biology News(10 mins):ACT Genomics Raises $8 Million in its First Private Funding Round 2Access Control Market Worth $10.4 Billion by 2020 2Access Control Market Worth $10.4 Billion by 2020 3Access Control Market Worth $10.4 Billion by 2020 4Marken startet Kampagne mit Patienten im Mittelpunkt 2Marken startet Kampagne mit Patienten im Mittelpunkt 3
... Princeton engineers have developed a sensor that may revolutionize how ... the process also help ensure the survival of two species ... credit goes to an African frog. In the wild, ... of amino acids -- on its skin to protect it ...
... of Medicine have found that new disease pathways involving ... Gaucher disease, a rare genetic disorder in which fatty ... enlargement, osteoporosis, bone pain, and increased risk of cancer ... lead to less expensive and more effective ways to ...
... COLUMBIA, Mo. If finding the cure for a fungus ... of a detective show, University of Missouri Chemistry Professor John ... high-tech equipment to make a model that could eventually solve ... of Arts and Science, has joined forces with Pablo Sobrado, ...
Cached Biology News:New sensor derived from frogs may help fight bacteria and save wildlife 2New sensor derived from frogs may help fight bacteria and save wildlife 3Cheaper, more effective treatment of type 1 Gaucher disease possible 2X-ray diffraction may play key role in stopping 'kissing bug,' fungus 2
(Date:2/26/2015)... 26, 2015   Regulus Therapeutics Inc . (NASDAQ: ... discovery and development of innovative medicines targeting microRNAs, today ... and Chief Executive Officer of Regulus, will present a ... Annual Healthcare Conference on Wednesday, March 4, 2015 ... at the Boston Marriott Copley Place.  ...
(Date:2/26/2015)... 26, 2015  NuGene International, Inc. ("NuGene") (OTCQB: ... skin and hair rejuvenation, has announced that it ... record for investor relations and strategic communications. ... sales and diversification strategies – and we need ... shareholders," stated Ali Kharazmi CEO of NuGene when ...
(Date:2/26/2015)... Innovation is more urgent than ... parts of the world and transforming global markets ... manufacturing to health care, disruption is constantly underway. ... socio-political trends shake the foundations of established business ... CEOs to survive the next wave of mega-change. ...
(Date:2/26/2015)... Feb. 26, 2015 Ceres, Inc . ... in Oracle PartnerNetwork. In attaining Gold Level membership, Ceres ... establish Oracle-related knowledge in delivering Ceres, Persephone genome visualization ... customers. Originally developed for in-house use by ... in and out of massive amounts of genetic data, ...
Breaking Biology Technology:Regulus to Present at Cowen and Company 35th Annual Healthcare Conference 2Regulus to Present at Cowen and Company 35th Annual Healthcare Conference 3NuGene International, Inc. Selects Capital Market Relations for Strategic Investor Relations 2NuGene International, Inc. Selects Capital Market Relations for Strategic Investor Relations 3One Million Acts of Innovation Canada Creates Partnership with The Economist Events’ Innovation Forum 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 2Ceres Becomes Oracle PartnerNetwork Gold Level Partner 3Ceres Becomes Oracle PartnerNetwork Gold Level Partner 4
... Mich., Oct. 11 Compendia Bioscience, Inc.,today announced ... Track Award from,the National Cancer Institute to support ... Platform for Biopharmaceutical Research and,Development". (Logo: ... Ph.D., who will serve as the principal,investigator for ...
... the prevention and treatment of ... safety and comfort, BATESVILLE, Ind., Oct. 11 ... Hill-Rom subsidiary has,introduced a revolutionary new hospital bed surface ... Hill-Rom(R) E700 Wound Surface (a,low air loss therapy surface) ...
... provides pharmacy staff with the ability to ... manage every pharmaceutical in the hospital, MOUNTAIN VIEW, Calif. ... ), a leading provider,of system solutions to acute healthcare facilities, ... Chambersburg,Hospital has reduced cart-fill time from 16 man-hours to 90 ...
Cached Biology Technology:Compendia Bioscience Announces the Receipt of a $2.4M SBIR Award and Related Management Changes 2Hill-Rom Introduces New Wound Therapy Surface With Innovative Safety and Treatment Features 2Hill-Rom Introduces New Wound Therapy Surface With Innovative Safety and Treatment Features 3Hill-Rom Introduces New Wound Therapy Surface With Innovative Safety and Treatment Features 4Hill-Rom Introduces New Wound Therapy Surface With Innovative Safety and Treatment Features 5Chambersburg Hospital Streamlines Pharmacy Process and Increases Patient Safety With Omnicell WorkflowRx 5.0 2Chambersburg Hospital Streamlines Pharmacy Process and Increases Patient Safety With Omnicell WorkflowRx 5.0 3
A univariate (peak height or area) quantitative multi-component analysis package....
... H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH 2 (Disulfide ... peptide and 1 ... I-labelled peptide, please see ... ([ 1 2 ...
... is a dramatic breakthrough in accurate, small-volume bulk ... resolution, the micro 1 has unique advantages not ... micro 1 never needs re-calibration as do other ... on an LCD Display , Graphical Row Selection ...
... high-throuput screening of a biological systems phenotype, ... changes in the expression levels of the ... studied, classified and compared to each other, ... a glance. Automatized scanning of the hybridized ...
Biology Products: