Navigation Links
NIST calculations may improve temperature measures for microfluidics
Date:9/9/2009

If you wanted to know if your child had a fever or be certain that the roast in the oven was thoroughly cooked, you would, of course, use a thermometer that you trusted to give accurate readings at any temperature within its range. However, it isn't that simple for researchers who need to measure temperatures in microfluidic systemstiny, channel-lined devices used in medical diagnostics, DNA forensics and "lab-on-a-chip" chemical analyzersas their current "thermometer" can only be precisely calibrated for one reference temperature. Now, researchers at the National Institute of Standards and Technology (NIST) have proposed a mathematical solution that enables researchers to calibrate the "thermometer" for microfluidic systems so that all temperatures are covered.

Reactions taking place in microfluidic systems often require heating, meaning that users must accurately monitor temperature changes in fluid volumes ranging from a few microliters (a droplet approximately 1 millimeter in diameter) to sub-nanoliters (a droplet approximately 1/10 of millimeter in diameter). A common DNA analysis technique, for example, depends heavily on precise temperature cycling. Ordinary thermometers or other temperature probes are useless at such tiny dimensions, so some groups have turned to temperature-sensitive fluorescent dyes, particularly rhodamine B. The intensity of the dye's fluorescence decreases with increasing temperature. The idea is that the dye can be used as a noninvasive way to map the range of temperatures occurring within a microfluidic system during heating and, in turn, provide a means of calibrating that system for experiments.

However, the technique currently requires the user to base all readings on the fluorescence at a single reference temperature. Previous groups have developed "calibration curves" that relate temperature to rhodmaine B fluorescent intensity based on a reference temperature of about 23 degrees Celsius (a technique first p
'/>"/>

Contact: Michael E. Newman
michael.newman@nist.gov
301-975-3025
National Institute of Standards and Technology (NIST)
Source:Eurekalert

Page: 1 2

Related biology news :

1. New Iowa State supercomputer, Cystorm, unleashes 28.16 trillion calculations per second
2. Shortcuts of the mind lead to miscalculations of weight and caloric intake, says Penn study
3. Carnegie Mellon urges industry to broaden carbon footprint calculations
4. Icy calculations on a hot topic
5. A breath of fresh air could improve drug toxicity screening
6. U-Iowa improves delivery of cancer-fighting molecules
7. Novel polymer could improve protein-based drugs
8. Water quality improves after lawn fertilizer ban, study shows
9. Improved air quality during Beijing Olympics could inform pollution-curbing policies
10. Technology improves salmon passage at hydropower dams
11. Short stressful events may improve working memory
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2015)... 2015 Research and ... the "Body-Worn Temperature Sensors Market - Global ... 2014 - 2020" report to their offering. ... the global body-worn temperature sensors market. The global ... the basis of types, care setting, patient demographic, ...
(Date:6/17/2015)... GERMANTOWN, Maryland , June 17, 2015 ... Produktlinie mit DNA-Tests verbessert den Analyseprozess und senkt Laborkosten ... Frankfurt Prime Standard: QIA) hat heute in den ... Investigator ® für die forensische ... Kits zur Erstellung genetischer Fingerabdrücke bieten eine integrierte Lösung ...
(Date:6/16/2015)... , June 16, 2015  With the increasing ... security remains a top concern. The recent compromise of ... the need for strong authentication within government agencies. ... a biometric one-time password (OTP) authenticator, has been submitted ... (FIPS) 140-2 Level 3 validation for tamper proofing. ...
Breaking Biology News(10 mins):Body-Worn Temperature Sensors Market - Global Industry Analysis 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 3QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 4QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 5QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 6Government Ready Biometric Security Approaching as HYPR Corp. Files FIPS 140-2 Level 3 Validation for Its Proprietary Biometric Token 2Government Ready Biometric Security Approaching as HYPR Corp. Files FIPS 140-2 Level 3 Validation for Its Proprietary Biometric Token 3
... recently sent to President Obama, more than 200 organizations, ... lauded the President for his outstanding leadership in advancing ... the letter below. Dear Mr. President: ... higher education communities, we wish to commend you and ...
... and limited water availability are major stresses for plants ... Ben-Gurion University of the Negev has announced the ... a subsidiary of Bayer CropScience based in Ghent, Belgium, ... builds upon the expertise and breakthrough results from Dr. ...
... is certainly not free of risk. Since 2005, the ... and Gttingen have registered a total of 17 patients ... pharmacologist Dieter Mller and his coauthors describe the documented ... Deutsches rzteblatt International (Dtsch Arztebl Int 2009; 106(13): ...
Cached Biology News:Business, scientific, higher education groups laud President Obama's commitment to science 2Ben-Gurion University of the Negev signs collaborative contract with Bayer CropScience 2
(Date:7/3/2015)... , July 3, 2015  Pomerantz LLP announces ... Puma Biotechnology, Inc. ("Puma" or the "Company")(NYSE: PBYI ... filed in United States District Court, Central District of ... is on behalf of a class consisting of all ... 23, 2014 and May 13, 2015 inclusive (the "Class ...
(Date:7/2/2015)... ... July 03, 2015 , ... Cuvettes have been used in countless labs for decades. ... find the cuvette they needed. As expected, this was a daunting and tiring process ... part because they were not able to navigate the complex catalog structure. , Now thanks ...
(Date:7/2/2015)... 2015  Spherix Incorporated (Nasdaq: SPEX ) -- an intellectual ... of intellectual property, today announced a litigation update. ... Verizon Services Corp. et al. , Case No. 1:14-cv-00721-GBL-TCB, ... District of Virginia , the Court ... certain key claims in favor of the Defendants on ...
(Date:7/2/2015)... ... ... Sleepless nights will become obsolete as Luzi , a sophisticated smart ... June 23. Sound sleepers and the sleep deprived both will love Luzi for its ... integration of the Bluetooth speaker, alarm clock and ability to charge various devices, including ...
Breaking Biology Technology:SHAREHOLDER ALERT: Pomerantz Law Firm Reminds Shareholders with Losses on their Investment in Puma Biotechnology, Inc. of Class Action Lawsuit and Upcoming Deadline - PBYI 2SHAREHOLDER ALERT: Pomerantz Law Firm Reminds Shareholders with Losses on their Investment in Puma Biotechnology, Inc. of Class Action Lawsuit and Upcoming Deadline - PBYI 3SHAREHOLDER ALERT: Pomerantz Law Firm Reminds Shareholders with Losses on their Investment in Puma Biotechnology, Inc. of Class Action Lawsuit and Upcoming Deadline - PBYI 4New Cuvette E-Commerce Website Launched by FireflySci 2Spherix Issues A Litigation Update 2Spherix Issues A Litigation Update 3Luzi Smart Lamp Recently Launched Indiegogo Campaign 2Luzi Smart Lamp Recently Launched Indiegogo Campaign 3
... ORLANDO, Fla., Sept. 20 HelixLife™ recently launched ... DNA Products (Vitamins & Skin Serum), Anti-Acne Skin ... These product lines were developed in partnership with ... solutions to personal health and skin care using ...
... Amex: NBS ) ("NeoStem" or the "Company"), an ... announced today that its CEO, Dr. Robin Smith, is appearing ... FOX Business Network.   The show,s first segment ... air each upcoming Saturday at 1:30 p.m. Eastern Time through ...
... Agreement With L-1 Identity Solutions for the Purchase... -- PARIS, September 20, 2010 ... ... --> ... s = ,; var first_result; // Results are keyed by longUrl, so we need to grab the ...
Cached Biology Technology:HelixLife Launches Custom Health Supplements, Anti-Aging and Acne Skin Serums 2FOX Business Network Airing In-Depth Look at NeoStem 2FOX Business Network Airing In-Depth Look at NeoStem 3Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 2Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 3Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 4Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 5Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 6Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 7Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 8Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 9Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 10Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 11Safran Enters Into a Definitive Agreement With L-1 Identity Solutions for the Purchase of L-1 Biometrics and ID Management Solutions Businesses 12
Salmonella typhimurium Immunogen: Heat inactivated bacterial cells of Salmonella typhimurium B Storage: 4 C...
... High Performance, 5 ml. The same ... HiTrap Streptavidin columns for fast, reliable ... into Tricorn 5/50 GL, XK 16/20, ... purifications are required.Extremely useful for exploiting ...
... Immunogen: Synthetic peptide derived ... human SENP1. Specificity: Specific ... SENP1. Reactivity: Human (positive ... Hep2 cell lysates HL-60 cell ...
...
Biology Products: