Navigation Links
NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves
Date:9/25/2008

CLEMSON The National Institutes of Health (NIH) has awarded Naren Vyavahare, Hunter Endowed Chair and professor of bioengineering at Clemson University, more than $1.5 million over four years to develop durable bioprosthetic heart valves (BHVs).

Aortic valves taken from pigs are used in thousands of human heart valve replacement surgeries annually, but they have a high rate of failure due to degeneration and calcification. It is estimated more than 50 percent fail within five to 15 years of implantation. Vyavahare's goal is to extend the biological durability of BHVs beyond 20 years.

"We've identified a problem where viscoelasticity is lost during tissue fixation and after implantation, and maintaining the structural integrity of the tissue matrix in the processed tissue is essential for these types of implants to work," said Vyavahare. "Our recent studies show that the chemical linking of neomycin to tissue, an inhibitor of the enzymes that degrade the tissue matrix, lead to significantly better stabilization of the valve tissue."

Vyavahare says improvements in durability will allow surgeons to implant the valves in the younger patient population.

Vyavahare and his group at Clemson have studied the problem of calcification in arteries and heart valves for nine years. The long-term fatigue damage study funded by NIH is unprecedented in the BHV field. The Clemson group has collaborations with the University of Pittsburgh and the University of Minnesota.


'/>"/>

Contact: Susan Polowczuk
spolowc@clemson.edu
864-656-2063
Clemson University
Source:Eurekalert

Page: 1

Related biology news :

1. The American Society of Plant Biologists announces 2007 awards
2. Singapore National Science and Technology Awards
3. Homeland Security awards 2 grants to Rutgers for nuclear threat detection
4. NIH awards nearly $23M to University of Chicago for translational research
5. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
6. PETA awards $120,000 to Duluth Foundation for advancing non-animal tests
7. NIH awards UC $9 million grant to improve patient point-of-care technologies
8. NIST announces 56 new awards for innovative technology research and development
9. USP awards verified mark to Dr. Reddys Laboratories, Ltd. ingredients
10. Simons Foundation awards Emory scientists $3M for autism gene research
11. NIH grants $33 M in institutional development awards to 3 states
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/16/2017)... --  Bridge Patient Portal , an enterprise patient ... Systems , an electronic medical record solutions developer ... a partnership to build an interface between the ... products, including Centricity Practice Solution (CPS), Centricity Business ... integrations will allow healthcare delivery networks using GE ...
(Date:4/18/2017)... April 18, 2017  Socionext Inc., a global expert in SoC-based ... edge server, the M820, which features the company,s hybrid codec technology. ... by Tera Probe, Inc., will be showcased during the upcoming Medtec ... show at the Las Vegas Convention Center ... Click here ...
(Date:4/11/2017)... 11, 2017 Crossmatch®, a globally-recognized leader ... today announced that it has been awarded a ... Activity (IARPA) to develop next-generation Presentation Attack Detection ... "Innovation has been a driving force within Crossmatch ... allow us to innovate and develop new technologies ...
Breaking Biology News(10 mins):
(Date:5/23/2017)... ... May 23, 2017 , ... Genedata, a ... anniversary, marking the occasion with a strong presence at Bio-IT World Conference & ... further extends an invitation to all attendees to view posters on the ...
(Date:5/23/2017)... ... May 23, 2017 , ... Energetiq Technology, a ... a facility expansion to accommodate its rapid growth. , The renovations at the ... renovation of the existing areas. The expansion includes, a state-of-the-art engineering facility, and ...
(Date:5/23/2017)... ... May 23, 2017 , ... Customers often ... control technology again and again. METTLER TOLEDO has released two new videos that ... illustrate how integration of the ACT350 into Siemens and Allen Bradley PLCs is ...
(Date:5/21/2017)... CA (PRWEB) , ... May 19, 2017 , ... ... annual meeting and educational conference of the American Association of Bioanalysts (AAB) and ... Galleria Hotel in Houston. The conference reinforces AAB’s commitment to excellence in clinical ...
Breaking Biology Technology: