Navigation Links
NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves
Date:9/25/2008

CLEMSON The National Institutes of Health (NIH) has awarded Naren Vyavahare, Hunter Endowed Chair and professor of bioengineering at Clemson University, more than $1.5 million over four years to develop durable bioprosthetic heart valves (BHVs).

Aortic valves taken from pigs are used in thousands of human heart valve replacement surgeries annually, but they have a high rate of failure due to degeneration and calcification. It is estimated more than 50 percent fail within five to 15 years of implantation. Vyavahare's goal is to extend the biological durability of BHVs beyond 20 years.

"We've identified a problem where viscoelasticity is lost during tissue fixation and after implantation, and maintaining the structural integrity of the tissue matrix in the processed tissue is essential for these types of implants to work," said Vyavahare. "Our recent studies show that the chemical linking of neomycin to tissue, an inhibitor of the enzymes that degrade the tissue matrix, lead to significantly better stabilization of the valve tissue."

Vyavahare says improvements in durability will allow surgeons to implant the valves in the younger patient population.

Vyavahare and his group at Clemson have studied the problem of calcification in arteries and heart valves for nine years. The long-term fatigue damage study funded by NIH is unprecedented in the BHV field. The Clemson group has collaborations with the University of Pittsburgh and the University of Minnesota.


'/>"/>

Contact: Susan Polowczuk
spolowc@clemson.edu
864-656-2063
Clemson University
Source:Eurekalert

Page: 1

Related biology news :

1. The American Society of Plant Biologists announces 2007 awards
2. Singapore National Science and Technology Awards
3. Homeland Security awards 2 grants to Rutgers for nuclear threat detection
4. NIH awards nearly $23M to University of Chicago for translational research
5. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
6. PETA awards $120,000 to Duluth Foundation for advancing non-animal tests
7. NIH awards UC $9 million grant to improve patient point-of-care technologies
8. NIST announces 56 new awards for innovative technology research and development
9. USP awards verified mark to Dr. Reddys Laboratories, Ltd. ingredients
10. Simons Foundation awards Emory scientists $3M for autism gene research
11. NIH grants $33 M in institutional development awards to 3 states
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)...  BellBrook Labs, a leader in high throughput screening ... a TR-FRET (time resolved Forster resonance energy transfer) ... high throughput screening assay for glycosyltransferases and other ... sensitive detection of hundreds of human and microbial ...
(Date:1/22/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD and NXTDW) a ... the recent success of the Wocket™ smart wallet at CES 2015 in ... was named as one of the "11 Hot Products at CES" in ... At CES So Far" by Newseveryday.com and "The top 10 gadgets from ...
(Date:1/22/2015)... YORK , Jan. 21, 2015  Analyst Report Issued by ... Card Brands report showed that planet-wide, transactions at merchants on ... while the total number of credit, debit, and prepaid cards ... U.S. were victims of fraudulent card usage in 2012, and ...
Breaking Biology News(10 mins):BellBrook Labs Launches a High Throughput Screening Assay for Glycosyltransferases with TR-FRET Readout 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2
... Australia, the United Kingdom and United States, including University of ... tactics, such as assisted migration, in the face of the ... policy ideas in a paper published July 18 in the ... that both the rapid rate of climate change and the ...
... as they evolve, biologists have unearthed several interesting patterns. ... members of a taxonomic group -- such as the ... elephant are often thousands or millions of times ... time two SFI researchers explain these patterns within an ...
... a close relative of the toadfish, doesn,t need good looks to ... nest for his potential partner, he calls to nearby females by ... buoyancy. The sound he makes is not a song or a ... a ballad. Female midshipman find it very alluring, and they only ...
Cached Biology News:Global warming experts recommend drastic measures to save species 2Predicting the distribution of creatures great and small 2When fish talk, scientists listen 2
(Date:1/22/2015)... Diego, California (PRWEB) January 22, 2015 ... Promotional Offer to their comprehensive portfolio of Eppendorf ... allows customers to purchase a Centrifuge 5424/5424 R and ... Bundle of either Eppendorf Research plus or Eppendorf Reference ...
(Date:1/22/2015)... Madison, WI (PRWEB) January 22, 2015 Dr. ... at the 12th annual Scripps Natural Supplements Pre-Conference seminar on ... Supplements Conference is an annual continuing education conference for health ... 15th and included the topic of probiotics in health. Dr. ...
(Date:1/22/2015)... January 22, 2015 Selexis SA, a ... Research Cell Banks (RCBs) used for drug discovery to ... Banks will include Next-Generation Sequencing (NGS) data ... de-risks biologic manufacturing by ensuring the integrity of the ...
(Date:1/22/2015)... , Nueva Jersey , 22 de enero ... for Biomedical Research abre hoy su llamada a nominaciones ... cuya investigación científica ha hecho, o tiene el potencial ... salud humana. Las nominaciones se aceptarán hasta el 15 ...
Breaking Biology Technology:Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4
... AcelRx Pharmaceuticals, Inc.,today announced positive results from ... efficacy of its lead product candidate, ARX-01, for ... replacement surgery.,The primary endpoint evaluated pain intensity (Sum ... 12-hour study period compared to baseline.,Results demonstrated that ...
... PAREXEL International Corporation,(Nasdaq: PRXL ), ... it has established an alliance with Safe Implementation,of ... network of,clinical sites with specialized capabilities in the ... from SITS, access to more than 800,investigator sites ...
... report that the small fraction of people who know ... finding has led many to assume that the public ... popular awareness grows, education expands and commercialization increases. , ... Cultural Cognition Project at Yale Law School in collaboration ...
Cached Biology Technology:AcelRx Pharmaceuticals Reports Positive Results From a Phase 2 Clinical Trial of Sublingual Sufentanil NanoTabs(TM) in Treating Post-Operative Pain 2AcelRx Pharmaceuticals Reports Positive Results From a Phase 2 Clinical Trial of Sublingual Sufentanil NanoTabs(TM) in Treating Post-Operative Pain 3PAREXEL Establishes Alliance with SITS Network of Clinical Sites Specializing in Stroke Studies 2PAREXEL Establishes Alliance with SITS Network of Clinical Sites Specializing in Stroke Studies 3PAREXEL Establishes Alliance with SITS Network of Clinical Sites Specializing in Stroke Studies 4Nanotech: To know it is not necessarily to love it 2
iNOS/NOS Type II Purified Anti-Mouse, Anti-Rat, Anti-Human clone Polyclonal, Isotype Rabbit Ig, 150 µg Consult technical datasheet for details....
... 100-240 V, uses multiplex suspension array technology ... up to 100 proteins and peptides in ... is composed of up to 100 color-coded ... conjugated with a unique reactant specific to ...
... (HTF) system, 100-240 V, is an optional ... that automates delivery of up to 20 ... array reader. The HTF system automatically draws ... container to constantly maintain a reservoir of ...
Cell Culture Flask, 75 cm, nontreated polystyrene...
Biology Products: