Navigation Links
NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves
Date:9/25/2008

CLEMSON The National Institutes of Health (NIH) has awarded Naren Vyavahare, Hunter Endowed Chair and professor of bioengineering at Clemson University, more than $1.5 million over four years to develop durable bioprosthetic heart valves (BHVs).

Aortic valves taken from pigs are used in thousands of human heart valve replacement surgeries annually, but they have a high rate of failure due to degeneration and calcification. It is estimated more than 50 percent fail within five to 15 years of implantation. Vyavahare's goal is to extend the biological durability of BHVs beyond 20 years.

"We've identified a problem where viscoelasticity is lost during tissue fixation and after implantation, and maintaining the structural integrity of the tissue matrix in the processed tissue is essential for these types of implants to work," said Vyavahare. "Our recent studies show that the chemical linking of neomycin to tissue, an inhibitor of the enzymes that degrade the tissue matrix, lead to significantly better stabilization of the valve tissue."

Vyavahare says improvements in durability will allow surgeons to implant the valves in the younger patient population.

Vyavahare and his group at Clemson have studied the problem of calcification in arteries and heart valves for nine years. The long-term fatigue damage study funded by NIH is unprecedented in the BHV field. The Clemson group has collaborations with the University of Pittsburgh and the University of Minnesota.


'/>"/>

Contact: Susan Polowczuk
spolowc@clemson.edu
864-656-2063
Clemson University
Source:Eurekalert

Page: 1

Related biology news :

1. The American Society of Plant Biologists announces 2007 awards
2. Singapore National Science and Technology Awards
3. Homeland Security awards 2 grants to Rutgers for nuclear threat detection
4. NIH awards nearly $23M to University of Chicago for translational research
5. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
6. PETA awards $120,000 to Duluth Foundation for advancing non-animal tests
7. NIH awards UC $9 million grant to improve patient point-of-care technologies
8. NIST announces 56 new awards for innovative technology research and development
9. USP awards verified mark to Dr. Reddys Laboratories, Ltd. ingredients
10. Simons Foundation awards Emory scientists $3M for autism gene research
11. NIH grants $33 M in institutional development awards to 3 states
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2015)... Research and Markets( ... "Huawei Ascend Mate 7 Fingerprint Sensor - ... Huawei,s technological choice for the fingerprint ... Apple,s and Samsung,s one. The Ascend Mate 7 ... Cards, a main actor in capacitive sensing human ...
(Date:6/23/2015)... 23, 2015   MedNet Solutions , an ... entire spectrum of clinical research, is pleased to ... , the company,s intuitive, flexible and affordable cloud-based ... 2015 Stevie® Award by the American Business ... Website category.  The American Business Awards are considered ...
(Date:6/23/2015)... 2015   Valencell, a leader in ... a recent study that illustrates its PerformTek biometric ... activity. In a study conducted at Valencell,s Biometric ... the Apple Watch against a chest strap – ... activity. The study demonstrated that Valencell,s biometric technology ...
Breaking Biology News(10 mins):Huawei Ascend Mate 7 Fingerprint Sensor - Reverse Costing Analysis 2MedNet Solutions' iMedNet eClinical Wins Silver Stevie Award 2Valencell Delivers Breakthrough Heart Rate Accuracy on the Wrist 2Valencell Delivers Breakthrough Heart Rate Accuracy on the Wrist 3
... PalmSecure(TM) Biometric Authentication, Self-Service Check In, Credit Card Scanning ... for Physician PracticesCHICAGO and SUNNYVALE, Calif., April 7 ... ) and Fujitsu , a leading ... today unveiled the Allscripts Patient Kiosk ...
... Company,Limited, a global provider of fingerprint recognition software and ... Fingerprint,Scanner. , FS90 uses a ... a very small form factor. Its size is 57(L) ... one half of Futronic FS80 USB2.0 Fingerprint Scanner but,can ...
... -- Which is a better strategy, specializing in ... more profitable than organic farming? Is it less ... of Wisconsin,s College of Agriculture and Life Sciences ... Wisconsin Integrated Cropping Systems Trial (WICST) in 1990. ...
Cached Biology News:Allscripts Integrates Electronic Health Records with Innovative Patient Kiosk 2Allscripts Integrates Electronic Health Records with Innovative Patient Kiosk 3Allscripts Integrates Electronic Health Records with Innovative Patient Kiosk 4Allscripts Integrates Electronic Health Records with Innovative Patient Kiosk 5Allscripts Integrates Electronic Health Records with Innovative Patient Kiosk 6Allscripts Integrates Electronic Health Records with Innovative Patient Kiosk 7Futronic Launches FS90 USB2.0 Mini Fingerprint Scanner 2
(Date:7/1/2015)... BANGALORE, India , July 1, 2015 /PRNewswire/ ... uses next generation sequencing technology to empower cancer care, ... as chief executive officer. In his expanded role ... for all strategy, business expansion and worldwide operations effective ... as Strand,s chairman and CEO since its founding in ...
(Date:7/1/2015)... InferMed , s ... will augment ... s olutions suite   Elsevier , ... and services, announced today the acquisition of  InferMed , a ... company. InferMed,s Arezzo technology supports clinicians in choosing ...
(Date:6/30/2015)... ... 2015 , ... Students and faculty from Beijing City University ... “Integrative Biotechnology,” an applied biotechnology course team-taught by faculty members from both institutions. ... from both universities and is taught on both continents. , “Our alliance with ...
(Date:6/30/2015)... 30, 2015  Today, Americord Registry, one of the fastest ... Horne , a partner at Kirkland & Ellis LLP, as ... Logo - http://photos.prnewswire.com/prnh/20150630/226958LOGO   "We are thrilled ... says Martin Smithmyer , CEO of Americord. "He brings ... that will assist Americord,s growth and vision." ...
Breaking Biology Technology:Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 2Strand Life Sciences Names Scott A. Storrer CEO as Company Continues Global Expansion with Focus on Precision Medicine Product 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 2Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 3Elsevier Acquires InferMed, Provider of Clinical Decision Support Technology 4Rivier University and Beijing City University Academic and Cultural Exchanges Begin 2Americord Registry Announces Andrew Horne as Advisory Board Member 2
... Division of Par Pharmaceutical with Initial Focus on ... ... N.J., Sept. 28 /PRNewswire-FirstCall/ - Par,Pharmaceutical Companies, Inc. (NYSE: ... prescription drugs, through the,establishment and introduction of Strativa Pharmaceuticals, its ...
... Calif., Sept. 28 Avicena Group,Inc. (OTC Bulletin ... nervous system therapeutics for neurodegenerative,diseases, announced today the ... the,Company,s Board of Directors, effective October 30, 2007. ... served as a member of the Company,s,Scientific Advisory ...
... CardioDynamics (Nasdaq:,CDIC), the innovator and leader of BioZ(R) ... received market clearance from,the U.S. Food and Drug ... medical record (EMR) interface capability for its BioZ ... a co-development partnership between,the Company and Philips Medical ...
Cached Biology Technology:Introducing Strativa Pharmaceuticals 2Introducing Strativa Pharmaceuticals 3Introducing Strativa Pharmaceuticals 4Introducing Strativa Pharmaceuticals 5Avicena Appoints Dr. M. Flint Beal to Board of Directors 2Avicena Appoints Dr. M. Flint Beal to Board of Directors 3Avicena Appoints Dr. M. Flint Beal to Board of Directors 4CardioDynamics Receives FDA 510(k) Clearance for Innovative Clinical Parameters and Electronic Medical Record Compatibility 2CardioDynamics Receives FDA 510(k) Clearance for Innovative Clinical Parameters and Electronic Medical Record Compatibility 3
BD BioCoat Laminin 100 mm Culture Dishes, tissue-culture treated polystyrene with a uniform application of mouse laminin....
... is used as an internal standard for ... dilution mass spectrometry. 5-OxoETE is a polyunsaturated ... 5-HETE in human neutrophils. It stimulates cytosolic ... of 2 nM. 5-OxoETE selectively stimulates the ...
... The dsRNA Marker consists of ten ... 200, 300, 400, 500 and 1,000 base ... size marker for determinating sizes of double-stranded ... in the dsRNA Marker is adjusted to ...
... White to off-white solid. ... glycosylation and blocks the formation of ... vitro against Gram-positive bacteria, yeasts, ... of functional thrombin receptors on human ...
Biology Products: