Navigation Links
NIH awards Clemson bioengineer $1.5 million to improve durability of tissue heart valves
Date:9/25/2008

CLEMSON The National Institutes of Health (NIH) has awarded Naren Vyavahare, Hunter Endowed Chair and professor of bioengineering at Clemson University, more than $1.5 million over four years to develop durable bioprosthetic heart valves (BHVs).

Aortic valves taken from pigs are used in thousands of human heart valve replacement surgeries annually, but they have a high rate of failure due to degeneration and calcification. It is estimated more than 50 percent fail within five to 15 years of implantation. Vyavahare's goal is to extend the biological durability of BHVs beyond 20 years.

"We've identified a problem where viscoelasticity is lost during tissue fixation and after implantation, and maintaining the structural integrity of the tissue matrix in the processed tissue is essential for these types of implants to work," said Vyavahare. "Our recent studies show that the chemical linking of neomycin to tissue, an inhibitor of the enzymes that degrade the tissue matrix, lead to significantly better stabilization of the valve tissue."

Vyavahare says improvements in durability will allow surgeons to implant the valves in the younger patient population.

Vyavahare and his group at Clemson have studied the problem of calcification in arteries and heart valves for nine years. The long-term fatigue damage study funded by NIH is unprecedented in the BHV field. The Clemson group has collaborations with the University of Pittsburgh and the University of Minnesota.


'/>"/>

Contact: Susan Polowczuk
spolowc@clemson.edu
864-656-2063
Clemson University
Source:Eurekalert

Page: 1

Related biology news :

1. The American Society of Plant Biologists announces 2007 awards
2. Singapore National Science and Technology Awards
3. Homeland Security awards 2 grants to Rutgers for nuclear threat detection
4. NIH awards nearly $23M to University of Chicago for translational research
5. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
6. PETA awards $120,000 to Duluth Foundation for advancing non-animal tests
7. NIH awards UC $9 million grant to improve patient point-of-care technologies
8. NIST announces 56 new awards for innovative technology research and development
9. USP awards verified mark to Dr. Reddys Laboratories, Ltd. ingredients
10. Simons Foundation awards Emory scientists $3M for autism gene research
11. NIH grants $33 M in institutional development awards to 3 states
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/11/2014)... 11, 2014  Forensicon, Inc., a Chicago ... to announce the promotion of Yaniv Schiff ... Forensics. In Schiff,s new role as Director, he will ... digital forensics examiners and provide leadership within the company,s ... http://photos.prnewswire.com/prnh/20141110/157719 Schiff joined Forensicon ...
(Date:11/7/2014)... professor, biomedical engineering, in the Grove School of ... have identified a molecule that could lead to ... forms of breast cancer. , Triple negative breast ... to aggressive proliferation and metastasis and a lack ... discovered the overexpression of intercellular adhesion molecule-1 (ICAM-1) ...
(Date:11/7/2014)... November 6, 2014 Leading Biometric companies ... mobile security revolutionizing online transactions.  Companies in focus today are: ... (NYSE: BABA ), Google Inc. (NASDAQ: ... Inc. (NASDAQ: EBAY ) and MasterCard Inc. (NYSE: ... and NXTDW), a biometric authentication company focused on the growing ...
Breaking Biology News(10 mins):Yaniv Schiff Promoted to Director of Digital Forensics at Forensicon, Inc. 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6
... have identified a link between the diversity of crops ... lakes and rivers. In a Frontiers in Ecology ... when the biodiversity of crops is high, less dissolved ... from agricultural fertilizers leaches through soils to groundwater and ...
... lice that infest humans: pubic lice, Pthirus pubis , ... A new article in BioMed Central,s open access Journal ... the two species. In the article, Robert ... by inspiration while pondering the question of why lice would ...
... Scientists intend to identify microbes that may cause preterm ... in preventing uterine contractions and an early birth, and look ... risk factors for prematurity. The work of seven researchers ... March of Dimes Prematurity Research Initiative (PRI) grants. The ...
Cached Biology News:Cropland diversity reduces nitrogen pollution 2March of Dimes provides $2.7 million in new funding for preterm birth research 2March of Dimes provides $2.7 million in new funding for preterm birth research 3
(Date:11/22/2014)... 2014 Prominent academics, leaders of ... on December 3rd at Genetic Rx, a networking ... will take place at the Joseph B. Martin ... discuss the present and future of genetic medicines—including ... gene editing—as well as the treatment of patients ...
(Date:11/22/2014)... MD (PRWEB) November 21, 2014 ... management solutions provider, has released Limfinity® version 5.1.4. ... installation projects of Limfinity® than ever in RURO’s ... configuration and minority framework enhancement. Limfinity® version 5.1.4 ... far above and beyond bug fixes! , Limfinity® ...
(Date:11/22/2014)... (PRWEB) November 22, 2014 The ... Analytical, Preparative), by Material (Metal, Glass, Plastic), by ... TLC, SFC] - Forecast to 2018” analyses and ... challenges in North America, Europe, Asia, and Rest ... tables and 15 figures spread through 135 pages ...
(Date:11/22/2014)... , Nov. 21, 2014  The element of ... emerging diseases, i.e., they strike without warning. Until now, ... warning of a viral outbreak, resulting in suboptimal responses ... Ebola currently. Photo - http://photos.prnewswire.com/prnh/20141121/160242 ... has now been removed because virus gene structural changes ...
Breaking Biology Technology:Pioneering Academics and Key Industry Leaders to Discuss Rare Diseases and the Emergence of New Genetic Medicines at Genetic Rx on December 3rd 2RURO Announces Limfinity® version 5.1.4 2Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 2Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 3Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 4Chiral Chromatography Columns Market worth $87.8 Million by 2018 - New Research Report by MarketsandMarkets 5Viruses' Advantage of Surprise is Lost 2
... even the resources of the world,s largest industrialized nations, scientists ... to find solutions. , Mark Shannon of the University of ... water resource research to address this crisis in a review ... "As dire as the growing problems are with a lack ...
... Blacksburg, Va. -- The ubiquity of mineral nanoparticles in ... intriguing properties provide Earth scientists with another dimension in ... team of scientists from seven universities in a review ... Nanominerals, Mineral Nanoparticles, and Earth Chemistry. , The way ...
... March 20 Scientists at the,Bio-Communications Research ... for,the Improvement of Human Functioning International (CIHFI), ... about its recent stem cell,discovery. The scientific ... stem cell population" received BioMed Central,s,Research Article ...
Cached Biology Technology:Countering an approaching water crisis 2Nanoscience will change the way we think about the world 2Nanoscience will change the way we think about the world 3Nanoscience will change the way we think about the world 4Nanoscience will change the way we think about the world 5Medical Research Award Goes to Adult Stem Cell Scientists at a Kansas Not-for-Profit Organization 2
... MW: 34.2kDa Formulation: 10mM HEPES, pH ... dithiothreitiol with 50% glycerol Properites: For ... Certificate of Analysis for individual lots ... followed by gel filtration and Mono-S ...
MitoScreen (JC-1) Kit , 100 tests Consult technical datasheet for details....
Thermal Printer Paper for Monolight(tm) Luminometer 1 each...
Conjugate Quality Control Evaluation Specificity: Conjugate Quality Control Evaluation ...
Biology Products: