Navigation Links
NIH TRND program announces next round of drug development projects
Date:11/15/2011

at afflicts more than 200 million people worldwide. The disease can cause severe anemia, diarrhea, internal bleeding and/or organ damage. Neglected diseases are conditions that inflict severe health burdens on the world's poorest people. This project aims to produce compounds that retain the positive anti-parasitic effects of the current treatment, praziquantel, which stuns and kills the worms while enabling lower and less frequent doses with potential for improved tolerability. This may allow broader access of a therapeutic to affected patients.

A drug candidate for treatment of Duchenne muscular dystrophy.
Peter Sazani, Ph.D., Executive Director of Preclinical Development
AVI BioPharma, Bothell, Wash.

Duchenne muscular dystrophy is an inherited, rapidly progressive form of muscular dystrophy affecting approximately 1 in 3,500 male births worldwide. This collaboration aims to develop a compound that would treat a sub-group of patients with a specific mutation responsible for Duchenne muscular dystrophy. The team will also investigate the general utility of this innovative treatment platform technology.

A pharmacological therapy for treatment of autoimmune pulmonary alveolar proteinosis.
Bruce C. Trapnell, M.D., Francis R. Luther Professor of Medicine and Pediatrics
Cincinnati Children's Hospital Medical Center-Research Foundation, Cincinnati, Ohio.

Pulmonary alveolar proteinosis is a rare lung disease characterized by the build-up of a grainy material in the air sacs of the lungs that causes breathing difficulties and can result in respiratory failure in rare cases. The protein therapeutic that is the subject of this collaboration will be developed as an inhaled therapy.

TRND has established data-driven milestones for each project to track progress and allow projects which do not achieve milestones in the established timeframe to be terminated, thus allowing other promising candid
'/>"/>

Contact: Geoffrey Spencer
spencerg@mail.nih.gov
301-451-8325
NIH/National Human Genome Research Institute
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. Researchers develop new self-training gene prediction program for fungi
2. Childrens gardening programs grow environmental stewards
3. Color My Pyramid nutrition education program battles obesity in DC schools
4. Yamanaka eliminates viral vector in stem cell reprogramming
5. Salk researchers successfully reprogram keratinocytes attached to a single hair
6. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
7. International Council for Science launches major research program on natural disasters
8. ICSU launches new program to understand the human impact on Earths life-support systems
9. SAIC Awarded $37 Million Contract to Support U.S. Army Program Executive Office - Enterprise Information Systems
10. TECNALIA leads five projects within the VII Framework Program
11. NWO and Academy launch research program with China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... and Spanish . ... released its Conservation Assessment for the Big Bend-Ro Bravo ... 29 priority conservation areas in a region straddling the ... in the states of Texas, Coahuila, and Chihuahua. This ... inhabited by rare and endangered plants and animals, and ...
(Date:4/23/2014)... of a unique rhythmic sound, recorded for decades in ... Antarctic minke whale ( Balaenoptera bonaerensis ). First described ... thought it sounded like a duck, the bio-duck sound ... Ocean, but its source has remained a mystery, until ... researchers deployed acoustic tags on two Antarctic minke whales ...
(Date:4/23/2014)... found evidence of an interaction between prenatal smoking ... in children, especially in girls. , "The interesting ... prenatal smoking will have behavioral problems. Some ... Assistant Professor at Sam Houston State University, College ... study. "One possible explanation for this is ...
Breaking Biology News(10 mins):Conservation priorities released for several protected areas along US-Mexico border 2Conservation priorities released for several protected areas along US-Mexico border 3Scientists identify source of mysterious sound in the Southern Ocean 2Scientists identify source of mysterious sound in the Southern Ocean 3Genetics risk, prenatal smoking may predict behavioral problems 2
... Berlin, Germany: A group of scientists from Hamburg ... cancer drug development, Europe,s largest cancer congress, ECCO 15 ... Dr Ilona Schonn, Director of Cell Culture Research at ... a preclinical drug test platform that would enable researchers ...
... National Institute of Standards and Technology (NIST) studying sugar-coated ... uncovered a delicate balancing act that makes the particles ... Just like individuals in a crowd respecting other people,s ... together, but not too close. In cooperation with ...
... A Georgia State University professor has been selected to ... Foundation to improve a computer simulation model that may ... assistant professor of computer science, will receive the four-year ... program. The grant is funded by the recent federal ...
Cached Biology News:New cancer drug test promises safer and more effective clinical trials 2New cancer drug test promises safer and more effective clinical trials 3Therapeutic nanoparticles give new meaning to sugar-coating medicine 2Georgia State researcher to use $1 million grant to improve computer models for fighting wildfires 2
(Date:1/15/2014)... 2014 TaiGen Biotechnology Company, Limited ("TaiGen") today announced ... a leading Russian pharmaceutical company, to develop and commercialize ... Federation , Turkey and ... a novel antibiotic for the treatment of bacterial infections ...
(Date:1/14/2014)... Communications, a leading provider of strategic communications services to corporations and ... the United States and Europe ... JD, is returning to the firm,s Washington, D.C. ... more than two years of service as Associate Commissioner for the ...
(Date:1/14/2014)... BETHESDA, Md. , Jan. 14, 2014 ... two institutes from the National Institutes of Health (NIH) ... safer, more effective treatments to patients on a faster ... Advancing Translational Sciences (NCATS) and the National Eye Institute ...
(Date:1/14/2014)... MD (PRWEB) January 14, 2014 ... to developing innovative information technology solutions for patients, ... health care stakeholders, announced today the signing of ... US Food and Drug Administration (FDA). This ...
Breaking Biology Technology:TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Former FDA Associate Commissioner Returns To 3D Communications 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2
... Nanotechnology Initiative (NNI) and the Oregon Nanoscience and Microtechnologies ... state, and local (RSL) nanotechnology initiatives. When: ... 30 Where: Portland, Oregon at the Embassy ... Who: Leaders of regional, state, and local ...
... CAMBRIDGE, Mass., March 14, 2012 /PRNewswire-iReach/ -- ... number 8,133,704 by the US Patent and Trademark Office ... The patent was issued on March 13, 2012 and ... variety of high-value chemicals with a total market value ...
... national search, Fitzsimons Redevelopment Authority (FRA) has named Steve ... beginning in late May. The announcement is made by ... Directors, who said: "Steve, a seasoned leader in the ... in Rochester, Minnesota." The appointment of Mr. ...
Cached Biology Technology:Registration now open: 2012 Regional, State, and Local Initiatives in Nanotechnology 2CELEXION Awarded Patent on Biosynthesis of Renewable Chemicals 2Fitzsimons Redevelopment Authority Names New President & CEO 2
... a variety of motion options - roller, ... unit. Shake, rock, roll and rotate motions!,, ... hybridization and blotting procedures requiring different settings, ... chamber uses a roller action to operate ...
... Magnetic Stand-96 is designed for paramagnetic bead ... 0.2 ml PCR plates with no additional ... base in a standard SBS 96-well microplate ... permanent magnets guarantees easy and fast (as ...
... magnetic particle based purification systems provide high ... any sample. They offer increased throughput and ... systems- KingFisher, KingFisher mL and KingFisher 96, ... l. Each system consists of an instrument, ...
... no-frills, basic SpeedVac concentrator designed for the ... unit still features a standard Teflon coated ... time and heat. It is designed for ... wide variety of different rotors for maximum ...
Biology Products: