Navigation Links
NIH TRND program announces next round of drug development projects
Date:11/15/2011

at afflicts more than 200 million people worldwide. The disease can cause severe anemia, diarrhea, internal bleeding and/or organ damage. Neglected diseases are conditions that inflict severe health burdens on the world's poorest people. This project aims to produce compounds that retain the positive anti-parasitic effects of the current treatment, praziquantel, which stuns and kills the worms while enabling lower and less frequent doses with potential for improved tolerability. This may allow broader access of a therapeutic to affected patients.

A drug candidate for treatment of Duchenne muscular dystrophy.
Peter Sazani, Ph.D., Executive Director of Preclinical Development
AVI BioPharma, Bothell, Wash.

Duchenne muscular dystrophy is an inherited, rapidly progressive form of muscular dystrophy affecting approximately 1 in 3,500 male births worldwide. This collaboration aims to develop a compound that would treat a sub-group of patients with a specific mutation responsible for Duchenne muscular dystrophy. The team will also investigate the general utility of this innovative treatment platform technology.

A pharmacological therapy for treatment of autoimmune pulmonary alveolar proteinosis.
Bruce C. Trapnell, M.D., Francis R. Luther Professor of Medicine and Pediatrics
Cincinnati Children's Hospital Medical Center-Research Foundation, Cincinnati, Ohio.

Pulmonary alveolar proteinosis is a rare lung disease characterized by the build-up of a grainy material in the air sacs of the lungs that causes breathing difficulties and can result in respiratory failure in rare cases. The protein therapeutic that is the subject of this collaboration will be developed as an inhaled therapy.

TRND has established data-driven milestones for each project to track progress and allow projects which do not achieve milestones in the established timeframe to be terminated, thus allowing other promising candid
'/>"/>

Contact: Geoffrey Spencer
spencerg@mail.nih.gov
301-451-8325
NIH/National Human Genome Research Institute
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. Researchers develop new self-training gene prediction program for fungi
2. Childrens gardening programs grow environmental stewards
3. Color My Pyramid nutrition education program battles obesity in DC schools
4. Yamanaka eliminates viral vector in stem cell reprogramming
5. Salk researchers successfully reprogram keratinocytes attached to a single hair
6. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
7. International Council for Science launches major research program on natural disasters
8. ICSU launches new program to understand the human impact on Earths life-support systems
9. SAIC Awarded $37 Million Contract to Support U.S. Army Program Executive Office - Enterprise Information Systems
10. TECNALIA leads five projects within the VII Framework Program
11. NWO and Academy launch research program with China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/4/2014)... , Dec. 3, 2014  Crossmatch™, a ... announced that its DigitalPersona ® Pro Enterprise ... have been deployed throughout First Bank branch locations ... South Carolina and Virginia. First Bank, ... Southern Pines, North Carolina , selected ...
(Date:11/21/2014)... , Nov. 19, 2014  Earlier this year ... York College, and one of the most prolific inventors ... that are transmitted from Smartphones to third party agencies. ... and has one of the earliest known patents in ... usage in the military, child care, elder care and ...
(Date:11/18/2014)... WASHINGTON , Nov. 18, 2014  The ... Security Industry Association today jointly announce the formation ... and release of its Identity and Biometric ... (Framework). The Framework received official support from BORDERPOL, ... governments to improve and provide expertise regarding border ...
Breaking Biology News(10 mins):First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 2Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 3Patented Biosensor Wearable Technology Provides a More Civilized Method of Quarantine 4Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 2Identity Management, Document Authentication and Biometric Companies Form "The Airport Entry and Exit Working Group", Releasing the Framework to Help Guide the Department of Homeland Security and Congress Towards Solutions 3
... a self-degradation response to the antidepressant Zoloft in yeast ... questions among scientists about how antidepressants work, as well ... linked to the neurotransmitter serotonin. In findings published ... in the lab of Ethan Perlstein, an associate research ...
... the analysis of flavanols in cocoa has been developed ... scientific division of Mars, Incorporated, and recently published in ... the research team,s expertise in flavanol chemistry and analytics, ... of flavanols found in cocoa and chocolate products. Foods ...
... April 23, 2012 /PRNewswire-iReach/  -- Global Information Inc. ... discounted registration for three important Boston healthcare conferences: ... Pioneers from across the rapidly maturing kinase inhibitors field ... lies ahead at the Next-Gen Kinase Inhibitors Conference ...
Cached Biology News:Yeast cell reaction to Zoloft suggests alternative cause, drug target for depression 2Yeast cell reaction to Zoloft suggests alternative cause, drug target for depression 3Yeast cell reaction to Zoloft suggests alternative cause, drug target for depression 4Scientists advance field of research with publication of newly validated method for analyzing flavanols in cocoa 2Attendees Save Up To $800 on Boston-area Pharmaceutical and Healthcare Conferences, Early Bird Discounts Expiring April 27 2Attendees Save Up To $800 on Boston-area Pharmaceutical and Healthcare Conferences, Early Bird Discounts Expiring April 27 3
(Date:12/19/2014)... FL (PRWEB) December 18, 2014 ... the nation’s leading specialty pharmacies, has an expanded ... as clinical pharmacy consultants for prescriber offices in ... expertise. , “We have a variety of ... For example, those specializing in hepatitis C help ...
(Date:12/19/2014)... LayerBio is an MIT spin-off developing ... The National Eye Institute (NEI) at the National Institutes ... SBIR grant to develop a drug-eluting intraocular lens (IOL) ... cause of vision loss in people over age 40 ... Dr. Ken Mandell, LayerBio’s Founder and CEO, "There is ...
(Date:12/19/2014)... 2014 Reports from CDC ... suffer from one or more chronic health conditions - ... can address some of these diseases, but may not ... sufferers face. While implanted nerve stimulation devices today offer ... nerve, which can induce side effects. , To ...
(Date:12/19/2014)... In contrast to traditional LED lights where the ... uses proprietary LED technology to incorporate their spectra in ... is critical in low proximity installations. The Valoya L-series ... lifetime which is up to four times longer than ... cost was clearly higher when compared to traditional fluorescent ...
Breaking Biology Technology:BioPlus Specialty Pharmacy Expands ‘Regional Pharmaceutical Care Liaison’ Team 2BioPlus Specialty Pharmacy Expands ‘Regional Pharmaceutical Care Liaison’ Team 3LayerBio Awarded NIH Grant to Develop a Drug Delivery Device for Cataract Surgery 2Draper Wins GSK Funding for Smaller, Smarter Implantable Devices 2
... May 12 Four prestigious universities have joined Bio Career ... for life science professionals. UCLA , Brown , ... board, joining 15 other major universities.The jobs board, ... sciences. While there are hundreds of life science career sites ...
... SAN DIEGO, May 12 Cardium Therapeutics (NYSE ... the Company will hold a conference call and ... for its Excellarate(TM) clinical development program. (Logo: ... the completion of recruitment for the Tissue Repair ...
... BMRN ) today announced that Jean-Jacques Bienaime, Chief ... the Deutsche Bank 34th Annual Health Care Conference in Boston ... Interested parties may access a live audio webcast of the ... www.BMRN.com . A replay of the ...
Cached Biology Technology:Four Major Universities Join Nation's Leading Postgrad Bio Jobs Board 2Cardium Announces Conference Call and Webcast to Review Recent Developments and Future Plans for the Excellarate(TM) Clinical Development Program 2Cardium Announces Conference Call and Webcast to Review Recent Developments and Future Plans for the Excellarate(TM) Clinical Development Program 3Cardium Announces Conference Call and Webcast to Review Recent Developments and Future Plans for the Excellarate(TM) Clinical Development Program 4Cardium Announces Conference Call and Webcast to Review Recent Developments and Future Plans for the Excellarate(TM) Clinical Development Program 5BioMarin to Present at the Deutsche Bank Health Care Conference 2
... be induced prior to DNA purification increasing ... of single-copy BACs with the high yields ... The kits provide the linearized vector and ... system) necessary to create a 10X human ...
... content or with significant secondary structure are ... subjected to PCR result in little or ... be increased by the addition of enhancing ... an effective PCR enhancer for GC-rich templates., ...
...
... EPICENTREs patented MasterAmp™ 10X PCR Enhancer ... and allows improved sensitivity and specificity ... Using MasterAmp PCR Enhancer in PCR ... DNA melting, increases enzyme?s thermal stability, ...
Biology Products: