Navigation Links
NIH TRND program announces next round of drug development projects
Date:11/15/2011

g principal investigators are:

An inhibitor compound for treatment of fibrodysplasia ossificans progressiva.
Kenneth D. Bloch, M.D., William T. G. Morton Professor of Anesthesia
Harvard Medical School, Massachusetts General Hospital, Boston.

Fibrodysplasia ossificans progressiva is a rare inherited disorder where muscle and connective tissue such as tendons and ligaments are gradually replaced by bone. The compound under development has shown efficacy in a mouse disease model.

Novel therapy for treatment of creatine transporter deficiency.
Rick Hawkins, Chief Executive Officer
Lumos Pharma, Inc., Austin, Texas.

Creatine transporter deficiency occurs from a mutation in a creatine transporter gene that prevents the transport of sufficient levels of creatine to the brain and results in cognitive function disorder. The lead compound has been evaluated in mice with creatine transporter deficiency and resulted in improved brain metabolism and cognitive function.

A compound for treatment of neonatal herpes simplex virus.
David W. Kimberlin, M.D., Professor of Pediatrics
The University of Alabama at Birmingham.

Neonatal herpes simplex virus is an infection transmitted from mother to child during childbirth. In preliminary studies, the candidate compound that will be advanced by this group shows anti-herpetic activity and can penetrate the central nervous system. This compound has received longstanding development support by National Institute of Allergy and Infectious Diseases, including funding of the current clinical trial that will collaborate closely with TRND.

Development of a deuterium-modified compound for treatment of Schistosomiasis.
Julie F. Liu, Ph.D., Director, Research Management
CoNCERT Pharmaceuticals Inc., Lexington, Mass.

Schistosomiasis is a neglected tropical disease caused by parasitic Schistosoma worms th
'/>"/>

Contact: Geoffrey Spencer
spencerg@mail.nih.gov
301-451-8325
NIH/National Human Genome Research Institute
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. Researchers develop new self-training gene prediction program for fungi
2. Childrens gardening programs grow environmental stewards
3. Color My Pyramid nutrition education program battles obesity in DC schools
4. Yamanaka eliminates viral vector in stem cell reprogramming
5. Salk researchers successfully reprogram keratinocytes attached to a single hair
6. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
7. International Council for Science launches major research program on natural disasters
8. ICSU launches new program to understand the human impact on Earths life-support systems
9. SAIC Awarded $37 Million Contract to Support U.S. Army Program Executive Office - Enterprise Information Systems
10. TECNALIA leads five projects within the VII Framework Program
11. NWO and Academy launch research program with China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... DURHAM, N.C. -- When you accidentally touch a hot ... know the basic neural circuits involved in sensing and ... out the molecular players. , Duke researchers have made ... molecule involved in pain in worms, and have built ... Sept. 2 in Nature Communications , may help ...
(Date:9/1/2014)... quality in the U.S. has improved steadily in recent ... overall dietary quality remains poor and disparities continue to ... new study from Harvard School of Public Health (HSPH). ... date that the extensive efforts by many groups and ... payoff, but it also indicates that these efforts need ...
(Date:9/1/2014)... minutes after birth, every child in the U.S. undergoes ... of conditions, including sickle cell disease. Thousands of children ... meaning many suffer and die from the disease each ... halt to at least some of those deaths. ... working in the lab of George Whitesides, the Woodford ...
Breaking Biology News(10 mins):Surprising new role for calcium in sensing pain 2Surprising new role for calcium in sensing pain 3Quality of US diet shows modest improvement, but overall remains poor 2Quality of US diet shows modest improvement, but overall remains poor 3Faster, cheaper tests for sickle cell 2Faster, cheaper tests for sickle cell 3
... created to provide a haven for both protected species ... Gothenburg have analysed species living on the seabed (benthic ... marine areas require special protection., , "It,s not possible ... park. That,s why I,ve done what experienced mushroom pickers ...
... This release is available in German . ... the carbohydrates they produce through photosynthesis in the leaves. However, ... heart to help transport this vital fuel. Instead, they use ... with colleagues from the Carnegie Institution for Science in California, ...
... of 34 institutions in 15 countries contributing to the measurements ... network, InGOS. , The network focuses on providing accurate information ... for a more vigorous climate action. In order to ... of greenhouse gas emissions is essential and not only ...
Cached Biology News:Life on Kosterhavet's seabed analyzed 2Sugar pump in plants identified 2Sugar pump in plants identified 3DTU is participating in a European network on measurement of greenhouse gases 2
(Date:8/30/2014)... (PRWEB) August 31, 2014 The ... a professional and in-depth study on the current ... Global and China. , The report provides a ... and industry chain structure. Global market analysis and ... focus on history, developments, trends and competitive landscape ...
(Date:8/29/2014)... According to a new market report published ... market was valued at USD 3,754.6 million in 2012 and ... 2019at a CAGR of 5.9% from 2013 to 2019. , ... is afflicted by bone and joint disorders, and this number ... has and will continue to increase the demand for orthobiologics. ...
(Date:8/29/2014)... (PRWEB) August 29, 2014 Three ... Energy's 2014 Hydrogen Production R&D Award ... by splitting water using sunlight. , Shared with ... and the University of Nevada, Las Vegas (UNLV), ... developing models of photoelectrochemical solar-hydrogen production and corrosion ...
(Date:8/28/2014)... SPIE Fellow Glenn Boreman, Professor and ... and Director of the Center for Optoelectronics and Optical ... and co-founder and Chairman of the Board of Plasmonics, ... Vice President of SPIE, the international society for optics ... recent election results at the Annual General Meeting of ...
Breaking Biology Technology:Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 2Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 3Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 2Global Orthobiologics Market to Reach $5,519.9 Million by 2019: Transparency Market Research 3Livermore Team Awarded for Hydrogen Production Research 2Glenn Boreman, UNC Professor and Plasmonics Co-Founder, Elected to SPIE Presidential Chain 2
... deep underground carries no significant threat to human health, despite ... Researchers found that the risk of death from poisoning ... rocks is about one in 100 million far less ... from the University of Edinburgh studied historical data on deaths ...
... University-University of Oregon Center for Sustainable Materials Chemistry, born ... moving into a second phase under a new five-year, ... through its Centers of Chemical Innovation Program, will allow ... and development and boost efforts to translate basic-level discoveries ...
... The Albert and Mary Lasker Foundation, ... research, announced today the winners of the 2011 Lasker Awards ... Horwich for basic medical research, Tu Youyou for ... of Health for public service. The Lasker Awards – considered ...
Cached Biology Technology:Health fears over CO2 storage are unfounded, study shows 2Center for Sustainable Materials Chemistry gets Phase 2 NSF grant 2Center for Sustainable Materials Chemistry gets Phase 2 NSF grant 3Center for Sustainable Materials Chemistry gets Phase 2 NSF grant 42011 Lasker Awards Honor Medical Research Pioneers 22011 Lasker Awards Honor Medical Research Pioneers 32011 Lasker Awards Honor Medical Research Pioneers 42011 Lasker Awards Honor Medical Research Pioneers 52011 Lasker Awards Honor Medical Research Pioneers 62011 Lasker Awards Honor Medical Research Pioneers 7
... SYBR Green II RNA gel ... gel stain that has bright fluorescence when ... gels, making it ideal for use with ... scanners or standard UV transilluminators. A 500 ...
... records analyzes and reports the data from any ... the a chart recorder. The final data is ... The end-point selection is automatic for Systolic, Mean, ... computed. The user is always in the position ...
... is taking automated patch clamping to a new ... to generate thousands of high quality data points ... in ion channel drug discovery and safety testing. ... afforded by conventional patch clamping can now be ...
... Reagents for the differentiation of mouse ... cell bodies exist in the midbrain, where ... nigra, the ventral tegmental area, and the ... rise to extensive forebrain dopamine innervation ( ...
Biology Products: