Navigation Links
NIH TRND program announces next round of drug development projects
Date:11/15/2011

Researchers will begin drug development projects for rare and neglected diseases that include potential treatments for a musculoskeletal disorder, a cognitive dysfunction disorder, a virus that affects the central nervous system of newborns, a parasitic worm infection, a form of muscular dystrophy and a rare lung disease. The six new projects are part of the National Institutes of Health's Therapeutics for Rare and Neglected Diseases (TRND) program.

"These projects reinforce NIH's commitment to translational research and the need to accelerate potential new treatments that benefit patients with rare and neglected diseases," said NIH Director Francis S. Collins, M.D., Ph.D. "It is wonderful that TRND scientists and their collaborators can advance such promising projects that may have otherwise remained stalled due to a lack of scientific or fiscal resources."

Congress created the TRND program to facilitate the development of new drugs for rare and neglected diseases. TRND bridges the wide gap in expertise and resources that often exists between basic research discoveries and the development and testing of new drugs in human subjects. As it develops new treatments, TRND also conducts research aimed at improving the drug development process. In contrast to conventional drug development efforts, TRND will publish successes and failures so that the broader drug development community can benefit from the work done.

To develop new medicines, TRND establishes partnerships with academic, government, biopharmaceutical and patient advocacy groups. TRND and its collaborators focus on the optimization and pre-clinical development of new drugs, as needed, advancing them from Food and Drug Administration (FDA) investigational, new-drug approval to first, in-human clinical trials.

Typically, the success rate for such projects is low, with 80 to 90 percent of projects failing in the pre-clinical phase and never making it to clinical trials.
'/>"/>

Contact: Geoffrey Spencer
spencerg@mail.nih.gov
301-451-8325
NIH/National Human Genome Research Institute
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. Researchers develop new self-training gene prediction program for fungi
2. Childrens gardening programs grow environmental stewards
3. Color My Pyramid nutrition education program battles obesity in DC schools
4. Yamanaka eliminates viral vector in stem cell reprogramming
5. Salk researchers successfully reprogram keratinocytes attached to a single hair
6. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
7. International Council for Science launches major research program on natural disasters
8. ICSU launches new program to understand the human impact on Earths life-support systems
9. SAIC Awarded $37 Million Contract to Support U.S. Army Program Executive Office - Enterprise Information Systems
10. TECNALIA leads five projects within the VII Framework Program
11. NWO and Academy launch research program with China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/14/2014)... led by researchers at the University of Massachusetts ... Miller School of Medicine (UMMSM) have identified what ... (manic depressive) disorder, a breakthrough that could lead ... as well as depression and other related mood ... week in Nature Molecular Psychiatry , show ...
(Date:10/14/2014)... takes between 10 and 20 years to develop, ... of intervention if detected early, which may be ... Australian clinical researchers. , Dr Jeremy Humphris ... of Medical Research, analysed medical histories and tumour ... cancer patients, operated on between 1994 and 20122. ...
(Date:10/14/2014)... Stanford University School of Medicine have discovered a link ... activation of muscle stem cells. Cells use autophagy to ... of nutrient deprivation. The scientists report in The ... operational it also seems to assist in the activation ... cells emerge from a quiescent state there is a ...
Breaking Biology News(10 mins):Rare genetic disease protects against bipolar disorder 2Rare genetic disease protects against bipolar disorder 3Early detection window when pancreatic cancer is in the family 2Autophagy helps fast track stem cell activation 2
... Weiblen and colleagues have found a faster way to ... Using a technique called DNA barcoding, which involves the ... and an international team of researchers studied populations of ... DNA barcodes showed that migratory patterns and caterpillar diets ...
... The humble papaya is gaining credibility in Western ... for generations. University of Florida researcher Nam Dang, ... dramatic anticancer effect against a broad range of lab-grown ... and pancreas. The researchers used an extract made from ...
... Subhash Khot, an associate professor at the Courant Institute ... 2010 Alan T. Waterman Award, which is given annually ... science and engineering supported by NSF. The honor includes ... research or advanced study in any field of science. ...
Cached Biology News:Papaya extract thwarts growth of cancer cells in lab tests 2NYU Courant professor wins NSF's Waterman Award 2
(Date:10/19/2014)... The Asia-Pacific Bromine Market report defines and ... and forecast of revenue. , Browse through the ... to get an idea of the in-depth analysis ... segmentation in the Asia-Pacific bromine market, and is ... http://www.micromarketmonitor.com/market/asia-pacific-bromine-6741503144.html , Bromine is a volatile ...
(Date:10/19/2014)... The report "Chocolate, Cocoa Beans, Lecithin, Sugar ... Trend and Forecast (2011 - 2016)," analyzes the ... studies the major market drivers, restraints, and opportunities for ... , The global chocolate market is expected to grow ... at an estimated CAGR of 2.7% from 2011 to ...
(Date:10/19/2014)... 19, 2014 According to market ... Points; WLAN Controllers; Wireless gateways)]- Global Advancements, Forecasts ... the global Outdoor Wi-Fi market with analysis and ... MarketsandMarkets also identifies the drivers and the restrains ... trends, opportunities and challenges. , Browse 65 market ...
(Date:10/18/2014)... The report "1,6-Hexanediol Market by Application and By ... the global market on the basis of its ... such as the key drivers, current trends and ... 81 Market Data Tables and 29 Figures spread ... Market by Application and by Geography - Trends ...
Breaking Biology Technology:The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bromine Market is estimated to grow to $4,080.1 million by 2018 - New Report by MicroMarket Monitor 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 2Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 3Chocolate Market Projected To Reach $98.3 Billion by 2016 - New Report by MarketsandMarkets 4Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 2Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 3Outdoor Wi-Fi Market (by Access Points, WLAN Controllers, Wireless gateways) Expected to Cross $37.2 Billion by 2018 - New Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 21,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 31,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 41,6-Hexanediol Market Projected to Reach $916.1 Million at a CAGR of 8.3% by 2019 – Report by MarketsandMarkets 5
... 18 ,Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in ... will release its financial,results for the full year 2008 ... Time (CET). To discuss these results, the Company will,conduct ... , The dial-in number for ...
... NEWTOWN, Pa., Feb. 18 Jennifer Brownstein, ... been named a 2009 Rising Star by ... Stars are up-and-coming professionals in various sectors ... advertising, public relations, medical education, and market ...
... Feb. 18 A new clinical study published this month ... reports that high-quality patient outcomes for breast-conserving surgery can be ... the few and the most recent studies of its kind ... breast cancer patients in the United States are treated at ...
Cached Biology Technology:AMT to Release Full Year 2008 Results on February 24, 2009 2Jennifer Brownstein, of CONNEXION Healthcare, Honored as 'Rising Star' by Healthcare Businesswomen's Association 2New Study Reports Improved Patient Outcomes for Breast Cancer Patients 2New Study Reports Improved Patient Outcomes for Breast Cancer Patients 3
Request Info...
... CultureWell cell culture systems provide ... cultured cells for staining and ... silicone gaskets preassembled with standard ... plates. The entire system is ...
... Captivate magnetic separator for ... used in conjunction with the ... C-21476) or other magnetic particles ... 96-well microplates. Cell Biology Cell ...
ANTI L-DOPA...
Biology Products: