Navigation Links
NIH TRND program announces next round of drug development projects
Date:11/15/2011

Researchers will begin drug development projects for rare and neglected diseases that include potential treatments for a musculoskeletal disorder, a cognitive dysfunction disorder, a virus that affects the central nervous system of newborns, a parasitic worm infection, a form of muscular dystrophy and a rare lung disease. The six new projects are part of the National Institutes of Health's Therapeutics for Rare and Neglected Diseases (TRND) program.

"These projects reinforce NIH's commitment to translational research and the need to accelerate potential new treatments that benefit patients with rare and neglected diseases," said NIH Director Francis S. Collins, M.D., Ph.D. "It is wonderful that TRND scientists and their collaborators can advance such promising projects that may have otherwise remained stalled due to a lack of scientific or fiscal resources."

Congress created the TRND program to facilitate the development of new drugs for rare and neglected diseases. TRND bridges the wide gap in expertise and resources that often exists between basic research discoveries and the development and testing of new drugs in human subjects. As it develops new treatments, TRND also conducts research aimed at improving the drug development process. In contrast to conventional drug development efforts, TRND will publish successes and failures so that the broader drug development community can benefit from the work done.

To develop new medicines, TRND establishes partnerships with academic, government, biopharmaceutical and patient advocacy groups. TRND and its collaborators focus on the optimization and pre-clinical development of new drugs, as needed, advancing them from Food and Drug Administration (FDA) investigational, new-drug approval to first, in-human clinical trials.

Typically, the success rate for such projects is low, with 80 to 90 percent of projects failing in the pre-clinical phase and never making it to clinical trials.
'/>"/>

Contact: Geoffrey Spencer
spencerg@mail.nih.gov
301-451-8325
NIH/National Human Genome Research Institute
Source:Eurekalert

Page: 1 2 3 4 5

Related biology news :

1. Researchers develop new self-training gene prediction program for fungi
2. Childrens gardening programs grow environmental stewards
3. Color My Pyramid nutrition education program battles obesity in DC schools
4. Yamanaka eliminates viral vector in stem cell reprogramming
5. Salk researchers successfully reprogram keratinocytes attached to a single hair
6. Evolved Machines Selected as a Prime Contractor for DARPA Program to Engineer an Artificial Olfaction System
7. International Council for Science launches major research program on natural disasters
8. ICSU launches new program to understand the human impact on Earths life-support systems
9. SAIC Awarded $37 Million Contract to Support U.S. Army Program Executive Office - Enterprise Information Systems
10. TECNALIA leads five projects within the VII Framework Program
11. NWO and Academy launch research program with China
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2014)... "electronic-nose" for sniffing the highly infectious bacteria C. ... has been developed by a team at the University ... team has demonstrated that it is possible to identify ... would lead to rapid diagnosis of the condition., What ... possible to identify different strains of the disease simply ...
(Date:8/31/2014)... Over the past several decades, malaria diagnosis has changed very ... technician smears the blood across a glass slide, stains it ... the Plasmodium parasite, which causes the disease. This approach gives ... blood an important measure of disease severity but ... , A research team from the Singapore-MIT Alliance for Research ...
(Date:8/29/2014)... University of Texas Medical Branch at Galveston has gone on ... completely protect monkeys against a lethal dose of Ebola virus ... the disease is severe. , Thomas Geisbert, professor of microbiology ... discussing advances in Ebola treatment research. The filoviruses known as ... of pathogens, with fatality rates of up to 90 percent. ...
Breaking Biology News(10 mins):Scientists develop 'electronic nose' for rapid detection of C. diff infection 2A new way to diagnose malaria 2A new way to diagnose malaria 3Leading Ebola researcher at UTMB says there's an effective treatment for Ebola 2
... first experimental evidence that birds can be deceived by camouflage ... today in Nature [3 March 2005]. , The idea that ... rapidly adopted by many armies as long ago as the ... colouration' has long been used to explain how insects such ...
... that radio-tracking could be affecting the animals they ... in the British Ecological Society's Journal of Applied ... with a "dramatic shift" in the sex ratio ... assumption that radio-tracking does not fundamentally affect the ...
... Blackburn is responsible for collecting and storing thousands of ... -- to make sure there's enough genetic material to ... deals with important livestock such as Holstein cattle and ... who is the coordinator of the animal section at ...
Cached Biology News:Radio-tracking associated with 'dramatic shift' in water vole sex ratio 2Making Sure Sacred Sheep Don't Become Extinct 2
(Date:8/31/2014)... Available spectra is similar for ... and cultivation of a wide range of plants. ... with proven patented and pending wide spectrum technology. ... in critical applications in contrast to growth spectra ... customers have a large variety of differently sized ...
(Date:8/29/2014)... Electronic circuits are based on electrons, but one of ... photonic circuits, i.e. circuits based on light (photons) instead ... to create a stream of single photons and control ... sorts of attempts to achieve this control, but now ... creating a steady stream of photons emitted one at ...
(Date:8/29/2014)... Hills, NY (PRWEB) August 29, 2014 ... Burnt Hills Veterinary Hospital are seeking candidates to participate ... dogs with osteoarthritis. The ultimate goal of this ... donor stem cells into one or two arthritically affected ... treated joints. , Candidates for the current investigational ...
(Date:8/28/2014)... USA (PRWEB) August 28, 2014 SPIE ... of Physics and Optical Science and Director of the ... of North Carolina at Charlotte, and co-founder and Chairman ... to serve as the 2015 Vice President of SPIE, ... 2014 President Philip Stahl announced recent election results at ...
Breaking Biology Technology:Breakthrough in light sources for new quantum technology 2Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2Glenn Boreman, UNC Professor and Plasmonics Co-Founder, Elected to SPIE Presidential Chain 2
... Previous Quarter, NEW YORK, May 15 ... biosensor and microprocessor technologies for,use in portable monitoring ... ended March 31, 2008., Gross revenues for ... quarter 2007 gross revenues. The increase in revenues ...
... YORK, May 15 American Oriental,Bioengineering, Inc. (NYSE: ... health through the development, manufacture and commercialization,of a ... ("OTC") products in,China, today released the following statement ... with the many victims of China,s earthquake and ...
... 15 /Xinhua-PRNewswire-FirstCall/ -- Huifeng Bio-,Pharmaceutical Technology, Inc. ... producer of plant extracts and pharmaceutical raw ... production, today,announced that there was no damage ... the Sichuan Earthquake., Immediately following the ...
Cached Biology Technology:SPO Medical Reports First Quarter 2008 Results 2SPO Medical Reports First Quarter 2008 Results 3American Oriental Bioengineering Comments on Earthquake 2Huifeng Bio-Pharmaceutical (HFGB) Announces No Earthquake Related Damage to Facilities 2
BD Primaria 35 mm Cell Culture Dish with Easy-Grip design, surface-modified polystyrene for enhanced cell culture. (20/sp, 200/ca) Packaging: 20 / sleeve, 500 / case ...
... is a software package that provides ... for custom buffer creation, set-up of ... crystallization trials. The software helps crystallographers ... automated protein crystallography: ...
The PROTEAN II slab gel casting stand is a component of the PROTEAN II XL and xi casting apparatus. It is supplied with gaskets....
Mouse monoclonal [H4B4] to LAMP2 - Lysosome Marker (Phycoerythrin) ( Abpromise for all tested applications). entrezGeneID: 3920 SwissProtID: P13473...
Biology Products: