Navigation Links
NC State researchers get to root of parasite genome
Date:9/23/2008

atodes is the development of a genetic map by our colleague, Dr. Valerie Williamson, at the University of California-Davis. The combination of a complete genome sequence with the genetic map makes this a unique and powerful system for the in-depth study of nematode-host interaction" Opperman says.

Besides being extremely important for the development of new and effective management strategies, the researchers say that the information gleaned from the genome sequence and genetic map will help scientists learn more about what they call the "themes of parasitism."

"All parasites have to do the same things to infect their hosts, whether the hosts are plants, animals or humans," Bird says. "Plants offer an advantage over those systems because they are easier to manipulate experimentally, and enable us to perform detailed experiments not easily done in animals, and not possible in humans."

The study shows that M. hapla has a somewhat smaller genome when compared with other microscopic worms like Caenorhabditis elegans, one of the models of scientific studies of animals. The northern root-knot nematode genome might be smaller, the researchers say, because the inside of the host plant's root provides an isolated environment compared to the soil.

"Having 99 percent of the genome sequenced allows you to not only know what's there, but to compare it to other nematodes to see what's missing from this genome," Bird says. "Finding potential Achilles' heels, what the nematode is getting from the plant and how is it really interacting with the plant are all more possible now."

The genome's reduced size made it easier to assemble the sequence, Opperman says. "In combination with an extensive database of plant parasitic nematode expressed genes from a previous project led by our Center for the Biology of Nematode Parasitism, this system provides a powerful platform for study of these important parasites," he added.

Although <
'/>"/>

Contact: Mick Kulikowski
mick_kulikowski@ncsu.edu
919-515-8387
North Carolina State University
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. Iowa State engineer works to clean and improve engine performance
2. Nitrate concentrations of ground water increasing in many areas of the United States
3. K-State professors USDA research shows mad cow disease also caused by genetic mutation
4. Iowa State wins $18.5M grant to create NSF Center for Biorenewable Chemicals
5. Stem cell research puts interstate rivalry on hold
6. NC State first university in nation to offer canine bone marrow transplants
7. Height linked to risk of prostate cancer development and progression
8. Iowa State University researcher shows proteins have controlled motions
9. Rapid test for pathogens developed by K-State researchers
10. Why a common treatment for prostate cancer ultimately fails
11. Sweets make young horses harder to train in Montana State study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/18/2013)... An increasing number of U.S. children are ... according to research presented at Digestive Disease Week ... researchers at the Cleveland Clinic Children,s Hospital found ... exhaled breath compared to their lean counterparts. The ... that can be correlated to potential complications associated ...
(Date:5/17/2013)... interaction of a group of proteins in the brain ... a new target that could increase cell survival. , ... of Biochemistry and published in the EMBO journal ... lead to new therapies for stroke and other brain ... the team which identified a protein, known as SUMO, ...
(Date:5/17/2013)... An international team of scientists using a new X-ray ... a living frog embryo in greater detail than ever ... biological research and the search for new treatments for ... Institut fr Technologie in Germany, in collaboration with the ... Argonne National Laboratory, released the most precise depiction ever ...
Breaking Biology News(10 mins):New research identifies risks, interventions for children's GI health 2New research identifies risks, interventions for children's GI health 3SUMO wrestling cells reveal new protective mechanism target for stroke 2New X-ray method shows how frog embryos could help thwart disease 2
... or water limit the size and photosynthetic capacity of a leaf? ... tree? These are all questions that Alana Oldham of Humboldt ... colleagues dangled from an ancient redwood tree well over a football ... trees, and many other plants, have thicker leaves on the top ...
... awarded a consortium of universities and companies headed by biologists ... next three years to conduct basic research that will pave ... competitive alternative to gasoline for our nation,s transportation fuel. ... $3 million from a consortium of biotechnology and energy companies, ...
... - A Purdue University researcher has found a sort of ... by about a week. Avtar Handa, a professor of ... a compound that slows aging and delays microbial decay in ... version of The Plant Journal , likely would transfer ...
Cached Biology News:Going out on a (redwood tree) limb 2Going out on a (redwood tree) limb 3DOE awards UC San Diego consortium $9 million for algal biofuels research 2Gene leads to longer shelf life for tomatoes, possibly other fruits 2
(Date:5/17/2013)... MD (PRWEB) May 17, 2013 ... of ezColony version 4.1, a versatile refinement to ... premier software solution, improves its advanced methodical management ... facilities with ezColony 4.1. The network-based platform provides ... conduct effective research. While continuing to emphasize streamlined ...
(Date:5/16/2013)... FL (PRWEB) May 16, 2013 ... named Barbara A. Myers, CAE, to the newly ... In her new role, Myers will be responsible ... development and production strategies, advancing the Society’s Member-led ... processes and continuing to refine organizational, membership and ...
(Date:5/16/2013)... Kitware , a leading ... new Phase II SBIR funding from the U.S. ... an open-source, high performance computing (HPC) simulation and ... researchers to select only the toolkits and applications ... or analysis tasks. , Manufacturers increasingly rely ...
(Date:5/16/2013)... On average, developing a new drug takes over ... this investment, less than 10% of drugs make it ... trial design optimally structured to balance time, cost and ... Sax, Global Head of the Center for Drug Development ... and technology in upfront clinical trial planning and design ...
Breaking Biology Technology:RURO Introduces ezColony 4.1 – The Versatile Transgenic Animal Colony Management Software 2ISPE Names Barbara A. Myers, CAE, as Vice President of Professional Development 2Kitware Develops a Customizable Simulation Framework to Provide HPC for Small to Mid-Sized Manufacturers 2Optimizing Clinical Trials Outcomes through Computer Assisted Design, New Life Science Webinar Hosted by Xtalks 2
... Calif., March 4, 2011 The Salk Institute is ... Esq. as Executive Director of the Salk Institute Office ... Dr. MacWright has extensive experience in academic ... Director of the University of Virginia Patent Foundation, where ...
... 2, 2011Toronto, ON and Helsinki, Finland) Dr. Andras ... of Mount Sinai Hospital and Dr. Timo Otonkoski,s ... Helsinki), as well as collaborators in Europe and ... adult cells to induced pluripotent stem (iPS) cells. ...
... 2011 Amgen (Nasdaq: AMGN ) will present ... Tuesday, March 8, 2011 at the Boston Marriott Copley Place, ... Amgen,s Senior Vice President of North American Commercial Operations, will ... the Events Calendar on Amgen,s website, www.amgen.com , under ...
Cached Biology Technology:Salk Welcomes National Leader in Academic Technology Transfer 2Scientists from Toronto and Helsinki discover genetic abnormalities after creation of stem cells 2Scientists from Toronto and Helsinki discover genetic abnormalities after creation of stem cells 3
RABBIT ANTI RHEB (IN) Immunogen: A 15 amino acid peptide located in the central region of human Rheb....
... Preparation contains a unique β-agarose digesting enzyme ... of intact DNA and RNA from low ... in TAE, TBE, MOPS, or phosphate buffers. ... the TAE, TBE, MOPS, and phosphate electrophoresis ...
... shortages in your laboratory or fellow researchers want ... problems and delays. • ... Bring us your idea and let us build ... under ISO 9001 quality assurance in design, development, ...
...
Biology Products: