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Mycobacterium tuberculosis: Our African follower for over 70,000 years!
Date:9/1/2013

age-like structures may have created conditions for the efficient human-to-human transmission of the disease, Gagneux suggests. This may also have increased the virulence of the bacteria over time.

The results indicate further that TB is unlikely to have jumped from domesticated animals to humans, as seen for other infectious diseases. "Simply, because Mycobacteria tuberculosis emerged long before humans started to domesticate animals," says Swiss TPH's Sebastien Gagneux.

New strategies to defeat tuberculosis

Tuberculosis remains a global threat. New drugs and vaccines are urgently needed to fight this poverty-related disease. Multidrug-resistance against first-line treatments is a growing threat in many countries. Therefore, the exploration of the evolutionary patterns of TB bacteria may help predicting future patterns of the disease. This may contribute to future drug discovery and to the design of improved strategies for disease control.


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Contact: Christian Heuss
christian.heuss@unibas.ch
41-612-848-683
Swiss Tropical and Public Health Institute
Source:Eurekalert

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