Navigation Links
Mussels inspire innovative new adhesive for surgery
Date:1/9/2013

ally, neither product is effective when used on wet tissue, a requirement of internal organ surgery, nor are there any current commercially available tissue adhesives or sealants appropriate for both external and internal use.

The researchers tested the newly developed iCMBAs on rats, using the adhesive and finger clamping to close three wounds for two minutes. Three other wounds were closed using sutures. The researchers reported their findings in a recent issue of Biomaterials.

The iCMBAs provided 2.5 to 8.0 times stronger adhesion in wet tissue conditions compared to fibrin glue. They also stopped bleeding instantly, facilitated wound healing, closed wounds without the use of sutures and offered controllable degradation.

"If you want the material to stay there for one week, we can control the polymer to degrade in one week," said Yang. "If you want the material to stay in the wound for more than a month, we can control the synthesis to make the materials degrade in one month."

The iCMBAs are also non-toxic, and because they are fully synthetic, they are unlikely to cause allergic reactions. Side effects were limited to mild inflammation.

"If you put any synthetic materials into your body," said Yang, "the body will generate some inflammation."

The researchers are now working on improving the formula.

"We are still optimizing our formulation," said Yang. "We are still trying to make the adhesion strength even stronger" to expand its use for things like broken bones where strong adhesion is tremendously important.

The researchers are also looking at adding in components that could control infection.

"We can introduce another component with anti-microbial properties, so it can do two functions at once," said Yang.

The iCMBAs could eventually be used in a wide range of surgical disciplines from suture and staple replacement to tissue grafts to treat hernias, ulcers and burns.
'/>"/>

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Silicone foul release coatings show promise to manage invasive mussels at water facilities
2. Mussel goo inspires blood vessel glue
3. University of Tennessee engineering professor looks to whirligig beetle for bio-inspired robots
4. Inspired: Canada funds 68 bold, inventive ways to improve health, save lives in developing countries
5. Origami inspires research into materials that self-assemble when exposed to light
6. Rice receives $1 million INSPIRE award from National Science Foundation
7. Frog calls inspire a new algorithm for wireless networks
8. Human eye inspires clog-free ink jet printer invented by MU researcher
9. New book inspires children to protect dugongs
10. MVI and Inovio partner to develop malaria vaccines using innovative vaccine delivery tech
11. NIH awards Penn scientists $10 million over 5 years for innovative research on single cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... BOSTON , July 23, 2014 ... and threat detection, announced today it has been named ... . The Market Guide replaces Gartner,s well-known Magic Quadrant ... Gartner categorized BioCatch as one of several vendors to ... biometric analysis will become a standard feature of at ...
(Date:7/23/2014)... SUP05 will play an increasingly important role in carbon ... minimum zones expand, according to research published this week ... Sciences . , University of British Columbia researchers plumbed ... Inlet, to chart how microbial community metabolism changes as ... very detailed picture of how SUP05 a bacterial ...
(Date:7/23/2014)...   MedNet Solutions , a global life ... systems, is pleased to announce that M. ... executive with over 25 years of experience, has ... be responsible for MedNet,s day-to-day operating activities, driving ... product/service delivery.  "We welcome Clareece, ...
Breaking Biology News(10 mins):BioCatch Featured in Gartner's 2014 Online Fraud Detection Market Guide 2BioCatch Featured in Gartner's 2014 Online Fraud Detection Market Guide 3Research charts the ecological impact of microbial respiration in the oxygen-starved ocean 2MedNet Appoints Clareece West As Chief Operating Officer 2
... of Technology have developed a miniature sensor that uses ... measure pollutants present in aqueous or gaseous environments. An ... be used during field-testing to rapidly detect many different ... allows water and air samples to be analyzed in ...
... using flexible electronics for next-generation biomedical devices has ... research program at Cornell, funded by the National ... received $3.2 million over five years from NSF,s ... Recruited IGERT fellows will work in teams to ...
... of a new approach to discover life on Mars ... a twelve-day, low-Earth orbit experiment to assess their survivability ... Mars. The new approach is based on technology ... so-called immunoassays are embodied in the Life Marker Chip ...
Cached Biology News:New microsensor measures volatile organic compounds in water and air on-site 2New microsensor measures volatile organic compounds in water and air on-site 3IGERT fellows to design biodevices using flexible electronics 2Life on Mars 'pregnancy test' successfully launched 2
(Date:7/23/2014)... Heroic worldwide conservation efforts have made great strides in ... in China, there are over 65 giant panda reserves ... But despite these efforts, just 1596 pandas remain in ... and zoos hope to save the panda by improving ... to the wild. Just how are these high-profile programs ...
(Date:7/23/2014)... , July 23, 2014 /PRNewswire-iReach/ -- Think Drinks ... performance for the long term. They are the first ... of sustained energy as an alternative to the temporary ... Drinks on Indiegogo on July 29, 2014, with hopes ... campaign. Photo - http://photos.prnewswire.com/prnh/20140723/129697 ...
(Date:7/23/2014)... 2014 Last year, Formedix ... leading global provider of data management solutions for clinical ... leading-edge system for electronic data capture (EDC) and clinical ... and study execution tools added TrialMaster to its Transform ... version of Transform for TrialMaster, is being released this ...
(Date:7/23/2014)... StemGenex® , the leading resource for ... at improving the lives of patients dealing with degenerative ... disease. StemGenex believes that a commitment to the ... when providing care to patients with degenerative diseases. ... accessible to the millions of individuals currently living with ...
Breaking Biology Technology:truBrain Neuroscientists To Launch More Effective, Healthier Alternative To Energy Drinks On Indiegogo 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 3StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 2StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study 3
... data reported for the first time show that ... (golimumab) resulted in significantly greater inhibition of structural ... with active rheumatoid arthritis (RA) and active psoriatic ... with SIMPONI resulted in a statistically significant reduction ...
... Oct. 19 Encorium Group, Inc. (Nasdaq: ENCO ... provides design, development, and management capabilities for clinical trials ... pharmaceutical companies, today announced that it has completed a ... with a private investor for an aggregate purchase price ...
... ... Data Analysis in Biomarker Project , ... Basel, Switzerland (PRWEB) October 19, 2009 -- Genedata, a leading provider ... collaboration with the Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, ...
Cached Biology Technology:New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 2New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 3New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 4New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 5New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 6New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 7New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 8New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 9New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 10New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 11New SIMPONI(TM) Data Show Inhibition of Joint Damage in Patients With Rheumatoid Arthritis and Psoriatic Arthritis 12Encorium Group, Inc. Completes $1.6 Million Private Placement of Common Stock and Executes Warrant Exchange Agreement; Ends Discussions to Sell Encorium OY 2Encorium Group, Inc. Completes $1.6 Million Private Placement of Common Stock and Executes Warrant Exchange Agreement; Ends Discussions to Sell Encorium OY 3Encorium Group, Inc. Completes $1.6 Million Private Placement of Common Stock and Executes Warrant Exchange Agreement; Ends Discussions to Sell Encorium OY 4Encorium Group, Inc. Completes $1.6 Million Private Placement of Common Stock and Executes Warrant Exchange Agreement; Ends Discussions to Sell Encorium OY 5Genedata and the Institute of Experimental Medicine, Academy of Sciences of the Czech Republic Collaborate on Asthma Bronchiale Project 2Genedata and the Institute of Experimental Medicine, Academy of Sciences of the Czech Republic Collaborate on Asthma Bronchiale Project 3Genedata and the Institute of Experimental Medicine, Academy of Sciences of the Czech Republic Collaborate on Asthma Bronchiale Project 4
... Enhancing signals in immunostaining ,This solution has ... allows to get clearer signal than the ... reduce the amount of secondary antibody used ... accordingly you can have images with high ...
Anti-human VEGFR-2/KDR (Protein-A Purified) Polyclonal Antibody...
... exists predominantly as XDH which converts hypoxanthine ... plasma antioxidant. During ischemia, XDH is ... XO by oxidation of essential sulfhydryl groups ... the amino-terminus. AO has a higher ...
Anti-TNKS2 Polyclonal AntibodyOther Sub-Family: not assigned-Other Applications: ELISA, Western Blot...
Biology Products: