Navigation Links
Mussels inspire innovative new adhesive for surgery
Date:1/9/2013

ally, neither product is effective when used on wet tissue, a requirement of internal organ surgery, nor are there any current commercially available tissue adhesives or sealants appropriate for both external and internal use.

The researchers tested the newly developed iCMBAs on rats, using the adhesive and finger clamping to close three wounds for two minutes. Three other wounds were closed using sutures. The researchers reported their findings in a recent issue of Biomaterials.

The iCMBAs provided 2.5 to 8.0 times stronger adhesion in wet tissue conditions compared to fibrin glue. They also stopped bleeding instantly, facilitated wound healing, closed wounds without the use of sutures and offered controllable degradation.

"If you want the material to stay there for one week, we can control the polymer to degrade in one week," said Yang. "If you want the material to stay in the wound for more than a month, we can control the synthesis to make the materials degrade in one month."

The iCMBAs are also non-toxic, and because they are fully synthetic, they are unlikely to cause allergic reactions. Side effects were limited to mild inflammation.

"If you put any synthetic materials into your body," said Yang, "the body will generate some inflammation."

The researchers are now working on improving the formula.

"We are still optimizing our formulation," said Yang. "We are still trying to make the adhesion strength even stronger" to expand its use for things like broken bones where strong adhesion is tremendously important.

The researchers are also looking at adding in components that could control infection.

"We can introduce another component with anti-microbial properties, so it can do two functions at once," said Yang.

The iCMBAs could eventually be used in a wide range of surgical disciplines from suture and staple replacement to tissue grafts to treat hernias, ulcers and burns.
'/>"/>

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Silicone foul release coatings show promise to manage invasive mussels at water facilities
2. Mussel goo inspires blood vessel glue
3. University of Tennessee engineering professor looks to whirligig beetle for bio-inspired robots
4. Inspired: Canada funds 68 bold, inventive ways to improve health, save lives in developing countries
5. Origami inspires research into materials that self-assemble when exposed to light
6. Rice receives $1 million INSPIRE award from National Science Foundation
7. Frog calls inspire a new algorithm for wireless networks
8. Human eye inspires clog-free ink jet printer invented by MU researcher
9. New book inspires children to protect dugongs
10. MVI and Inovio partner to develop malaria vaccines using innovative vaccine delivery tech
11. NIH awards Penn scientists $10 million over 5 years for innovative research on single cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/2/2015)... At its 2015 ACMG Annual Clinical Genetics ... the American College of Medical Genetics and Genomics (ACMG) ... Board.  Members of the ACMG Board of Directors serve ... advancing its policies and programs. ACMG is the national ... an eventful time in medical genetics and genomics.  We ...
(Date:4/2/2015)... April 2, 2015 Fingerprint Cards ... sensor FPC1025 from the distributor World Peace Industrial Group ... Q2 2015 although the major part of the shipments ... be used by smartphone manufacturers in China ... included in the communicated revenue guidance of + 1 000 ...
(Date:4/1/2015)... 2015   Medisafe ™, the leading global medication ... iOS and Android smartphones and tablets, ... the platform to allow patients to track and correlate ... time, patients will be able to visualize in real-time ... biometrics, such as glucose levels and blood pressure. ...
Breaking Biology News(10 mins):American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 110 Million 2Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2
... ACCOKEEK, Md., Sept. 10 Beretta U.S.A. Corp. announced,today the ... Navy for a,total of 10,576 M9 pistols (5,969 for the ... a multi-year contract between Beretta,U.S.A. and the U.S. Army, which ... branches of the U.S. Armed Forces. "We are always ...
... ,Communication Intelligence Corporation (OTC Bulletin Board: CICI) ("CIC"),a ... process,automation in the financial industry and the recognized ... of Michael Betts to,the CIC Board of Directors. ... experience in the insurance and,financial services industries and ...
... in 21st Year of Service and ... Suppliers Under One Roof, SUNNYVALE, Calif., Sept. 10 ... IDEMA today announced program,highlights for DISKCON USA 2007, the premier ... at the Hyatt Regency Hotel / Santa Clara,Convention Center in ...
Cached Biology News:U.S. Army and Navy Purchase Over 10,000 New Beretta M9 Pistols 2Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors 2Michael A. Betts, Seasoned Financial Services Executive, Joins CIC Board of Directors 3IDEMA Reveals Program Highlights for DISKCON USA 2007 2IDEMA Reveals Program Highlights for DISKCON USA 2007 3IDEMA Reveals Program Highlights for DISKCON USA 2007 4
(Date:4/24/2015)... April 24, 2015 Seoul Semiconductor ... for various applications in the lighting market. ... installations of this technology in emerging markets such ... a wide range of applications such as streetlight ... decorative lighting. , First launched in 2005 the ...
(Date:4/23/2015)... , April 23, 2015 /CNW/ - A new and ... award from North America,s ... Comparison won Silver in the "Sustainability, service" category ... The Brandcheck "Competitor Comparison" is a service that ... American and Global peers. This benchmarking process shows ...
(Date:4/23/2015)... SHANGHAI , April 23, 2015 WuXi ... open-access R&D capability and technology platform company serving the ... China and the ... release financial results for the first quarter of 2015 ... May 13, 2015 (which will be Thursday morning, May ...
(Date:4/23/2015)... Prospects for Leading Companies in OTC, Rx Pharmaceuticals ... We predict the global healthcare packaging market ... will grow at a CAGR of 6.3% between 2015 and ... and increasing functional requirements for healthcare packaging products are some ... packaging market. A global ageing population, changing lifestyles and ...
Breaking Biology Technology:Acrich Technology from Seoul Semiconductor Adopted in Installations Worldwide 2WuXi PharmaTech Schedules First-Quarter 2015 Earnings Release 2WuXi PharmaTech Schedules First-Quarter 2015 Earnings Release 3Healthcare Packaging Market Forecast 2015-2025 2Healthcare Packaging Market Forecast 2015-2025 3Healthcare Packaging Market Forecast 2015-2025 4Healthcare Packaging Market Forecast 2015-2025 5Healthcare Packaging Market Forecast 2015-2025 6Healthcare Packaging Market Forecast 2015-2025 7Healthcare Packaging Market Forecast 2015-2025 8Healthcare Packaging Market Forecast 2015-2025 9Healthcare Packaging Market Forecast 2015-2025 10
... GAINESVILLE, Fla. --- Algae is a livid green giveaway of ... that action in tiny particles that would turn different colors ... poor health in the blood. , Now, University of Florida ... clear a major hurdle to creating such "smart dust.",The feat, ...
... studies illustrating the value of in situ mid IR reaction monitoring ... ... Columbia, MD (PRWEB) January 18, 2009 -- METTLER TOLEDO invites ... Chemistry Using Real-Time In Situ FTIR presented by Dr. Jennifer ...
... 16 N-Viro International Corporation,(OTC Bulletin Board: NVIC), ... technologies to convert various types of waste into,beneficial ... Fuel(TM), has satisfied guidelines set forth by the ... alternative energy,source that may be utilized in commercial ...
Cached Biology Technology:Researchers: Molecular forklifts overcome obstacle to 'smart dust' 2Researchers: Molecular forklifts overcome obstacle to 'smart dust' 3N-Viro Fuel Technology Receives Alternative Energy Status From the U.S. Environmental Protection Agency 2N-Viro Fuel Technology Receives Alternative Energy Status From the U.S. Environmental Protection Agency 3N-Viro Fuel Technology Receives Alternative Energy Status From the U.S. Environmental Protection Agency 4
... oligodeoxynucleotides are random primers ... the 5' end with ... dyes and they are ... spot morphology, hybridization potential ...
EDTA, disodium salt, 1 kg. Ethylene diaminetetraacetic acid.Dihydrate. Assay: 99.0-101.0%, nuclease-free.Risks: 36, 37, 38 ; Safety Precautions: 22, 36, 37. Category: Nucleotides & Enzymes & Biochemi...
Mycoplasma tested...
Alkaline Phosphatase Stabilizer Solution, 1 L...
Biology Products: