Navigation Links
Mussels inspire innovative new adhesive for surgery
Date:1/9/2013

ally, neither product is effective when used on wet tissue, a requirement of internal organ surgery, nor are there any current commercially available tissue adhesives or sealants appropriate for both external and internal use.

The researchers tested the newly developed iCMBAs on rats, using the adhesive and finger clamping to close three wounds for two minutes. Three other wounds were closed using sutures. The researchers reported their findings in a recent issue of Biomaterials.

The iCMBAs provided 2.5 to 8.0 times stronger adhesion in wet tissue conditions compared to fibrin glue. They also stopped bleeding instantly, facilitated wound healing, closed wounds without the use of sutures and offered controllable degradation.

"If you want the material to stay there for one week, we can control the polymer to degrade in one week," said Yang. "If you want the material to stay in the wound for more than a month, we can control the synthesis to make the materials degrade in one month."

The iCMBAs are also non-toxic, and because they are fully synthetic, they are unlikely to cause allergic reactions. Side effects were limited to mild inflammation.

"If you put any synthetic materials into your body," said Yang, "the body will generate some inflammation."

The researchers are now working on improving the formula.

"We are still optimizing our formulation," said Yang. "We are still trying to make the adhesion strength even stronger" to expand its use for things like broken bones where strong adhesion is tremendously important.

The researchers are also looking at adding in components that could control infection.

"We can introduce another component with anti-microbial properties, so it can do two functions at once," said Yang.

The iCMBAs could eventually be used in a wide range of surgical disciplines from suture and staple replacement to tissue grafts to treat hernias, ulcers and burns.
'/>"/>

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Silicone foul release coatings show promise to manage invasive mussels at water facilities
2. Mussel goo inspires blood vessel glue
3. University of Tennessee engineering professor looks to whirligig beetle for bio-inspired robots
4. Inspired: Canada funds 68 bold, inventive ways to improve health, save lives in developing countries
5. Origami inspires research into materials that self-assemble when exposed to light
6. Rice receives $1 million INSPIRE award from National Science Foundation
7. Frog calls inspire a new algorithm for wireless networks
8. Human eye inspires clog-free ink jet printer invented by MU researcher
9. New book inspires children to protect dugongs
10. MVI and Inovio partner to develop malaria vaccines using innovative vaccine delivery tech
11. NIH awards Penn scientists $10 million over 5 years for innovative research on single cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2015)... 22, 2015 Research ... of the "Huawei Ascend Mate 7 Fingerprint ... their offering. Huawei,s technological choice for ... direction than Apple,s and Samsung,s one. The Ascend ... by Fingerprint Cards, a main actor in capacitive ...
(Date:6/23/2015)... RALEIGH, N.C. , June 23, 2015 /PRNewswire/ ... technology, today announced the results of a recent ... unmatched accuracy on the wrist during activity. In ... biometric technology was compared along with the Apple ... for accurately measuring heart rate during activity. The ...
(Date:6/17/2015)... , Deutschland und GERMANTOWN, Maryland ... Investigator ®   Produktlinie mit DNA-Tests ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: ... neue STR-Testkits der Produktlinie Investigator ... in den Markt eingeführt. Die neuen Kits zur Erstellung ...
Breaking Biology News(10 mins):Huawei Ascend Mate 7 Fingerprint Sensor - Reverse Costing Analysis 2Valencell Delivers Breakthrough Heart Rate Accuracy on the Wrist 2Valencell Delivers Breakthrough Heart Rate Accuracy on the Wrist 3QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 2QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 3QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 4QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 5QIAGEN bringt in den USA neue Kits für die forensische DNA-Analyse auf den Markt 6
... 5,893 leaks from aging natural gas pipelines have been found ... from Duke University and Boston University. A dozen of ... Some manholes had methane concentrations as high as 500,000 parts ... than the threshold at which explosions can occur. ...
... Researchers from the University of Toronto (U of T) have ... claims an individual,s nutritional needs vary by blood type--is not ... One . , "Based on the data of ... ,blood-type, diet theory," said the senior author of the study, ...
... RICHLAND, Wash. -- Researchers simulating how certain bacteria run ... secret Nature uses for electron travel. The results are ... the ground, and will help researchers use them in ... electricity. Within the bacteria,s protein-based wire, molecular groups ...
Cached Biology News:5,900 natural gas leaks discovered under Washington, D.C. 25,900 natural gas leaks discovered under Washington, D.C. 3Popular blood type diet debunked 2Hugging hemes help electrons hop 2Hugging hemes help electrons hop 3Hugging hemes help electrons hop 4
(Date:7/3/2015)... ... July 03, 2015 , ... The global failure analysis market is ... to 2020. The bioscience market is expected to grow at the highest CAGR of ... analysis equipment in the research labs and academic institutions for root cause analysis of ...
(Date:7/3/2015)... 3, 2015  Pomerantz LLP announces that a class ... ("Puma" or the "Company")(NYSE: PBYI ) and certain ... States District Court, Central District of California ... of a class consisting of all persons or entities ... May 13, 2015 inclusive (the "Class Period").  This class ...
(Date:7/2/2015)... , July 2, 2015 College of ... Eakins are gaining invaluable real-world experiences while serving ... this summer. The students will be working ... Wereszczynski,s research group at IIT. The internship came ... Tom Carter , Physics; Dr. Kathy Finan , ...
(Date:7/2/2015)... ... July 02, 2015 , ... Sleepless nights will become obsolete as ... sleep, launched its Indiegogo campaign on June 23. Sound sleepers and the sleep deprived ... it effortless to use, while the integration of the Bluetooth speaker, alarm clock and ...
Breaking Biology Technology:Failure Analysis Market to Grow at 7.52% CAGR to 2020 2Failure Analysis Market to Grow at 7.52% CAGR to 2020 3Failure Analysis Market to Grow at 7.52% CAGR to 2020 4Failure Analysis Market to Grow at 7.52% CAGR to 2020 5SHAREHOLDER ALERT: Pomerantz Law Firm Reminds Shareholders with Losses on their Investment in Puma Biotechnology, Inc. of Class Action Lawsuit and Upcoming Deadline - PBYI 2SHAREHOLDER ALERT: Pomerantz Law Firm Reminds Shareholders with Losses on their Investment in Puma Biotechnology, Inc. of Class Action Lawsuit and Upcoming Deadline - PBYI 3SHAREHOLDER ALERT: Pomerantz Law Firm Reminds Shareholders with Losses on their Investment in Puma Biotechnology, Inc. of Class Action Lawsuit and Upcoming Deadline - PBYI 4COD Students Participate in Prestigious Summer Internships 2Luzi Smart Lamp Recently Launched Indiegogo Campaign 2Luzi Smart Lamp Recently Launched Indiegogo Campaign 3
... Web-based reporting credited with state's top healthcare ranking , , ... the state's web-based quality reporting system with the state's top ... Agency for Healthcare Research and Quality. , ,The ... quality score among all 50 states based on 129 measures ...
... company secrets. He thinks business meetings can be toxic as ... to improve the flow of communication, and he thinks employees ... , ,There is a method to Jason Fried's ... the recent Wisconsin Entrepreneurs' Conference in Milwaukee. , ,The founder ...
... - Using innovation to grow the top line will be ... 7:30 to 9 a.m., at the Butte des Morts Country ... open to the public, will center on innovation and adding value ... by Todd Teske, executive vice president and chief operating officer of ...
Cached Biology Technology:Visions: Chicago software exec Jason Fried breaks (almost) all the rules 2Visions: Chicago software exec Jason Fried breaks (almost) all the rules 3
Designed for use with all 96-well SPRI reagent kits. Used with round bottom 96-well microplates, and 96-well thermal cycling plates....
... suitable for a broad range of applications. ... physiological signal such as ECG, EMG, SCR ... use with a wide range of bridge ... stimulus artefact clamp to avoid saturation when ...
... covers can be used with ... covers for stacking of covered ... for use with automated systems ... and non-ridged, are available for ...
... or 384-well PCR plates Dimples on both sides ... plates End tabs on Thermo-Mat™ 384 fit into ... sealing is achieved with either Thermo-Mat™ 96 or 384 ... lid thermal cyclers Fully autoclavable May ...
Biology Products: