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Mitochondrial mutations: When the cell's 2 genomes collide
Date:2/5/2013

tation in the same mitochondrial RNA gene the team studied in fruit flies.

Rand and his group are now conducting new experiments to trace more mito-nuclear incompatibilities within a single species to their genetic and biochemical roots.

"This paper provided proof of principle that we can identify these things and map them to their nucleotides," Rand said. "We want to ask how common is this and can we find other sources of this kind of breakdown in mito-nuclear crosstalk underlying disease."


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Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert  

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