Navigation Links
Mimicking nature at the nanoscale: Selective transport across a biomimetic nanopore
Date:6/20/2011

he development of synthetic systems that imitate biological structures and processes. Advances in nanotechnology now make it possible to study and shape matter at the nanometer scale, opening the way to imitate biological structures at the molecular level to both study and harness their ingenuity." The group of dr. Roderick Lim at the University of Basel purified the nuclear pore proteins and Dekkers group made the biomimetic nanopores of these by attaching these proteins to small holes in a solid-state support.

Selectivity

The new research, performed chiefly by lead author Stefan Kowalczyk, a graduate student in Dekkers lab, demonstrates that it is possible to establish a biomimetic nuclear pore and to monitor transport of individual proteins across the pore. Importantly, the biomimetic pore exhibits strong selectivity, just like the natural nuclear pore complex: ImpB proteins do pass the pores, whereas BSA proteins do not (as illustrated by the attached image). A differing degree of selectivity was found, depending on which exact nuclear pore proteins were used to functionalize the pore. The researchers have shown that the biomimetic pore is fully functional and can be used as a testing platform for studies of drug delivery into a cell's nucleus.


'/>"/>

Contact: Prof. Cees Dekker
c.dekker@tudelft.nl
Delft University of Technology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Mimicking nature, water-based artificial leaf produces electricity
2. Boston Univ., Veterans Affairs find sports brain trauma may cause disease mimicking ALS
3. Wildlife Conservation Society finds wild cat mimicking monkey calls
4. Some vocal-mimicking animals, particularly parrots, can move to a musical beat
5. GigaBlitz will turn high-resolution images of nature into global inventory of organisms, habitats
6. Nanotechnologists must take lessons from nature
7. How natures best ideas inspire innovative new technologies
8. Nature helps to solve a sticky problem
9. 2011 PerkinElmer Signature Genomic Laboratories Travel Award winner announced
10. Nature paper calls for carbon labeling
11. New data published in Nature Genetics demonstrate that tiny LNA-based compounds developed by Santaris Pharma A/S inhibit entire disease-associated microRNA families
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/16/2014)... land managers have a new synthesis of recent research ... (MMC) forests in the two states. , The ... Oregon and Washington: A Synthesis of the Relevant Biophysical ... technical report published by the U.S. Forest Service,s Pacific ... request from managers for a synthesis of the large ...
(Date:10/16/2014)... monocultures can be cultivated efficiently, they are anything ... caused by monoculture cultivation is becoming increasingly evident. ... crop form and are regarded as the sole ... – quite wrongfully, finds Bernhard Schmid, an ecology ... a novel form of agriculture and forestry. After ...
(Date:10/16/2014)... Post-menopausal women experienced improvements in vaginal atrophy, with ... bleeding, after 12 weeks of daily 10 milligram ... nutritional supplement previously shown to help relieve certain ... study reported in a poster at the North ... , "These data documented improved vaginal epithelium, without ...
Breaking Biology News(10 mins):New report synthesizes best available science on management of moist mixed-conifer forests 2Plant communities produce greater yield than monocultures 2Plant communities produce greater yield than monocultures 3S-equol supplements associated with improved measures of reproductive health in postmenopausal women 2
... Severe breathing disorders during sleep are associated with an ... published this week in the open access journal PLoS ... dying is most apparent in men between 40 and 70 ... specific link between this condition and death from coronary heart ...
... to those created by lightning strikes, Victor Ugaz, associate ... at Texas A&M University, has created a network of ... by serving as a three-dimensional vasculature for the support ... work, which was undertaken with colleague Arul Jayaraman and ...
... Hopkins researchers have developed a highly sensitive test to look ... cancer. This test, which detects both the presence ... who are at risk of developing the disease and could ... The new test was reported in a paper called ...
Cached Biology News:Severe breathing disorders during sleep are associated with an increased risk of dying 2Researcher says microchannels could advance tissue engineering methods 2Researcher says microchannels could advance tissue engineering methods 3Researcher says microchannels could advance tissue engineering methods 4New DNA test uses nanotechnology to find early signs of cancer 2New DNA test uses nanotechnology to find early signs of cancer 3
(Date:10/22/2014)... (PRWEB) October 21, 2014 The ... the inorganic refrigerants market in Americas with analysis ... TOC of the Americas Inorganic Refrigerants Market report, ... provided. This also provides a glimpse of the ... is supported by various tables and figures. ...
(Date:10/22/2014)... Cranford, NJ (PRWEB) October 22, 2014 ... technologies and services – has been working with a ... Health and New Haven Farms Community Farming Collaborative to ... iPad-based ePRO solution. The study, which started in ... Wellness program that provides participants weekly exposure to and ...
(Date:10/22/2014)... 22, 2014 According to new ... Service Type (Consulting, Integration, Deployment & Support), by ... Model (Public, Private, Others (Hybrid & Community)) - ... and segments the Cloud Professional Services Market into ... of revenues. It also identifies the drivers and ...
(Date:10/22/2014)... DUBLIN , Oct. 22, 2014 ... "Organic Electronics Market by Material, by Application, Geography ... report to their offering. Organic electronics, ... a branch of material science which deals with small ... as organic because small molecules and polymers are carbon ...
Breaking Biology Technology:The Americas Inorganic Refrigerants Market is estimated to grow to $71.6 million by 2018 - New Report by MicroMarket Monitor 2The Americas Inorganic Refrigerants Market is estimated to grow to $71.6 million by 2018 - New Report by MicroMarket Monitor 3myPROpad™ Topic of Panel Discussion at the Yale Food Systems Symposium 2myPROpad™ Topic of Panel Discussion at the Yale Food Systems Symposium 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 4Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 5Global Organic Electronics (Semiconductor, Conductive, Dielectric and Substrate) Market - Analysis and Forecast (2014 - 2020) 2Global Organic Electronics (Semiconductor, Conductive, Dielectric and Substrate) Market - Analysis and Forecast (2014 - 2020) 3
... Sonia Moralejo Garca at the University of the Basque Country ... and other magnetic devices of wide industrial application. , It ... that are ever smaller and that nanotechnology, although it its ... in our society. Who has not heard of nanotubes, nanoparticles ...
... Growth Plans, Technology Leadership, INDIANAPOLIS, Feb. 12 ... wholly owned subsidiary of The Dow Chemical,Company (NYSE: ... presentation made to investors,earlier today by Jerome Peribere, ... at the Goldman Sachs Agricultural Chemicals,Conference in New ...
... plc (LSE: SHP)(NASDAQ: SHPGY )(TSX: SHQ),the global specialty ... 21 February 2008., Results press release will ... 07:00 EST Investor meeting and conference call time: ... Analyst meeting and conference call:, Matthew Emmens, Chief ...
Cached Biology Technology:A researcher of UPV/EHU has designed nanomagnets for industry 2Dow AgroSciences' Success Presented to Wall Street 2Full Year 2007 Results Date Notification - 21 February 2008 2
... siRNA Tracker Intracellular Localization Kit provides a ... deliver siRNA, of your design, in an ... tracking experiments. Subcellular localization and functional inhibition ... following introduction of the labeled siRNA into ...
... IT siRNA Tracker Intracellular Localization Kit ... straight forward approach to directly label ... in an efficient yet non-destructive manner, ... localization and functional inhibition of target ...
Ideal for chemical processing that requires downward flow of exhaust fumes. Powderful 1200 CFM blower draws fumes into sub-surface bonded charcoal filter for safe removal of organic vapors (final HEP...
... Essentials Kit provides all the necessary materials and ... mir Vana miRNA Bioarrays when using a ... mir Vana miRNA Labeling Kit. The kit ... BA10001) that should be spiked into your miRNA ...
Biology Products: