Navigation Links
Mighty mesh
Date:1/23/2012

Cambridge, Mass. - January 23, 2012 - New research at Harvard explains how bacterial biofilms expand to form slimy mats on teeth, pipes, surgical instruments, and crops.

Through experiment and mathematical analysis, researchers have shown that the extracellular matrix (ECM), a mesh of proteins and sugars that can form outside bacterial cells, creates osmotic pressure that forces biofilms to swell and spread.

The ECM mechanism is so powerful that it can increase the radius of some biofilms five-fold within 24 hours.

The results have been published in the Proceedings of the National Academy of Sciences.

Biofilms, large colonies of bacteria that adhere to surfaces, can be harmful in a wide range of settings, resulting in tooth decay, hospital infections, agricultural damage, and corrosion. Finding ways to control or eliminate biofilms is a priority for many industries.

In order for a biofilm to grow, a group of bacterial cells must first adhere to a surface and then proliferate and spread. When a vast number of cells are present, this can translate into the creation of a filmy surface spanning several meters.

"Our work challenges the common picture of biofilms as sedentary communities by showing how cells in a biofilm cooperate to colonize surfaces," says lead author Agnese Seminara, a research associate at the Harvard School of Engineering and Applied Sciences (SEAS).

Several types of biofilms have been characterized based on composition and antibiotic resistance, but until now it has not been clear what roles the whip-like flagella and the ECM play in the outward movement of cells.

While the presence of a flagellum has traditionally been associated with greater movement capability, the new research has found that a flagellum actually confers little advantage in the formation of biofilms. In the Harvard study, mutant bacteria lacking flagella were able to spread at almost the same
'/>"/>

Contact: Caroline Perry
cperry@seas.harvard.edu
617-496-1351
Harvard University
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Fit females make more daughters, mighty males get grandsons
2. Simple little spud helps scientists crack potatos mighty genome
3. Mighty predatory mite and oil sprays may save eggplant production in Micronesia
4. Humans have a mighty bite
5. Mighty diatoms: Global climate feedback from microscopic algae
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mighty mesh
(Date:10/16/2014)... severe respiratory tract infections and worldwide claims the ... VIB and Ghent University have succeeded in developing ... virus infection. , Xavier Saelens (VIB/UGent): "We ... way for the development of a novel approach ... suffering in numerous small children and elderly people." ...
(Date:10/15/2014)... book ,Models of Life, is a non-traditional biophysics textbook ... The book is a journey of discovery into biological ... life and biological regulation. It is about how our ... communication between the billions of cells in an organism. ... relationships between principles, which can be found on both ...
(Date:10/15/2014)... 44th Rosenstiel Award for Distinguished Work in Biomedical Science ... mechanisms of genomic instability and its implications for the ... alumnus to win the Rosenstiel Award; the first, Rod ... is the Charles A. Janeway Professor of Pediatrics and ... investigator at the Howard Hughes Medical Institute at Boston ...
Breaking Biology News(10 mins):New perspectives for development of an RSV vaccine 2New book about life as seen from physics 2Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2
... Some parents of children with autism evaluate facial expressions ... a way that is strikingly similar to autistic patients ... Piven of the University of North Carolina at Chapel ... Institute of Technology. Piven, Adolphs and colleague ...
... in individuals of Asian descent increases the risk of ... the August Journal of Lipid Research . In ... this rare variant for apolipoprotein A-V had extremely high ... Apolipoprotein A-V is a recently discovered lipid-binding protein that ...
... BET DAGAN, ISRAEL - Table grapes are subject to serious ... the vine to dinner tables around the world. Mold and ... reduce grape quality during shipping and storage in retail produce ... are one way of ensuring that consumers get fresh, appealing ...
Cached Biology News:UNC, Caltech research finds further evidence for genetic contribution to autism 2UNC, Caltech research finds further evidence for genetic contribution to autism 3Genetic variant increases triglyceride levels in Asian-Americans 2Fresh from the grapevine to the table 2
(Date:10/25/2014)... Los Angeles, California (PRWEB) October 23, 2014 ... VDRM ), a specialty pharmaceutical company devoted to ... pursuing out-licensing partnerships in 2015. , ViaDerma has ... method, which allows for rapid mass transfer of ... into the body to provide immediate localized therapy. ...
(Date:10/25/2014)... Va. (PRWEB) October 24, 2014 ... the nation’s leading nonprofit authority on the ... healthcare information exchange, announces its appointment of four ... Workgroup. The workgroup leaders include:, , ... ,     Erik Pupo, Specialist Leader, Deloitte Consulting ...
(Date:10/25/2014)... 24, 2014 A new way to ... pitfalls of current skin grafting technologies, it also speeds ... The method, outlined in the October issue of STEM ... deep skin injuries that result from severe burns and ... the skin’s regenerative elements. These wounds heal by contraction, ...
(Date:10/25/2014)... , Oct. 24, 2014  RegeneRx Biopharmaceuticals, Inc. (OTCBB: ... presented at the Fourth International Symposium on Thymosins in ... Italy.  "When thymosin beta 4 (TB4) ... into the peritoneal cavity in a rodent model of ... throughout the brain parenchyma (the functional tissue of the ...
Breaking Biology Technology:ViaDerma, Inc. Announces Plans to Pursue Out-Licensing Partnerships in 2015 2ViaDerma, Inc. Announces Plans to Pursue Out-Licensing Partnerships in 2015 3WEDI Appoints Four New Security and Privacy Workgroup Co-chairs 2New engineering method shows promise for faster healing, more cosmetically appealing skin grafts 2New engineering method shows promise for faster healing, more cosmetically appealing skin grafts 3Researchers Report Thymosin Beta 4 Crosses Blood-Brain Barrier In Animal Stroke Model 2
... International,Corporation (Nasdaq: PRXL ) announced today that its ... Common Stock, which will be effected by,means of a ... will receive one additional share of,Common Stock for each ... of,February 22, 2008. The additional shares will be distributed ...
... Incorporated,(Nasdaq: GPRO ) announced today that Carl ... chief operating officer, effective March 1, 2008., ... 2007 as executive vice,president and chief operating officer. ... and development, manufacturing, and,sales and marketing., "Carl,s ...
... Feb. 11 BioSpace, the leading biotech,job board ... over 800,biotechnology and pharmaceutical job seekers to the ... CA., The BioSpace Career Fair attracted a ... diagnostics career,candidates from around southern California. The event ...
Cached Biology Technology:PAREXEL International Announces 2-For-1 Stock Split 2PAREXEL International Announces 2-For-1 Stock Split 3Carl Hull Named President and Chief Operating Officer of Gen-Probe 2Carl Hull Named President and Chief Operating Officer of Gen-Probe 3BioSpace Career Fair in San Diego Draws Record Number of Bioscience Candidates 2
... PureLink PCR Purification Kits provide rapid ... enzymes, short-failed PCR products, and salts from ... bind/wash/elute procedure:, provides two Binding Buffer ... bp* , can be performed in either ...
... PCR Cloning Kit offers the fastest ... cloning of blunt-end PCR products amplified ... includes the linearized and topoisomerase I-activated ... ligations without ligase (1). The pCR-Blunt ...
2.0 GHz Compaq Computer with 512 MB RAM, 32 MB AGP Graphics Card, 40 GB Hard Drive, 1 Serial Port & Open PCI Slot, Windows 2000 OS, MS Office, CD Read/Writer and 18 Flat Panel Monitor...
Blot Paper 7 x 8.5cm semi-dry western blots (order number RB-400)...
Biology Products: