Navigation Links
Middle school students co-author research on enzyme for activating promising disease-fighters
Date:7/28/2010

Grown-ups aren't the only ones making exciting scientific discoveries these days. Two middle school students from Wisconsin joined a team of scientists who are reporting the first glimpse of the innermost structure of a key bacterial enzyme. It helps activate certain antibiotics and anti-cancer agents so that those substances do their job. Their study appears in ACS' weekly journal Biochemistry. The student co-authors of the study are from Edgewood Campus Middle School in Madison and participated in Project CRYSTAL, a special program that provides middle school students with hands-on laboratory experience.

In the report, study leader Hazel Holden and colleagues note intense scientific interest in a chemical process called methylation, which increases the activity of DNA, proteins, and other substances in the body by transferring methyl (CH3) groups to them. Special enzymes called methyltransferases make methylation possible, and these proteins are very important in a myriad of key biological processes.

Holden and colleagues studied a bacterial methyltransferase involved in the production of tetronitrose, a component of the promising anti-cancer agent, tetrocarcin, and the antibiotic kijanimicin. The methyltransferase seems to play a key role in activating these disease-fighters. The scientists identified the 3D structure of this methyltransferase, a key step in determining how it works and how it might be modified for potential use in medicine.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert  

Page: 1

Related biology news :

1. Why your boss is white, middle-class and a show-off
2. Exercise increases brain growth factor and receptors, prevents stem cell drop in middle age
3. Study says middle class coral reef fish feel the economic squeeze
4. Many middle-aged and older Americans not getting adequate nutrition
5. UT multimedia program increases middle school interest in science
6. Overweight middle-aged women cut chances of enjoying healthy old age
7. Color My Pyramid nutrition education program battles obesity in DC schools
8. identiMetrics & BIO-key(R) Provide Biometric Finger Scanning for School Food Service Nationwide
9. NJIT sustainability expert to discuss high performance schools at seminar
10. Students eat more whole grains when its gradually added to school lunch
11. Eliminating soda from school diets does not affect overall consumption
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Middle school students co-author research on enzyme for activating promising disease-fighters
(Date:3/28/2017)... -- The report "Video Surveillance Market by ... Devices), Software (Video Analytics, VMS), and Service (VSaaS, Installation ... 2022", published by MarketsandMarkets, the market was valued at ... reach USD 75.64 Billion by 2022, at a CAGR ... considered for the study is 2016 and the forecast ...
(Date:3/23/2017)... 23, 2017 The report "Gesture Recognition and Touchless Sensing ... Geography - Global Forecast to 2022", published by MarketsandMarkets, the market is expected ... 29.63% between 2017 and 2022. Continue Reading ... ... ...
(Date:3/22/2017)... 21, 2017 Vigilant Solutions , a ... enforcement agencies, announced today the appointment of retired FBI ... public safety business development. Mr. Sheridan brings ... including a focus on the aviation transportation sector, to ... position, Mr. Sheridan served as the Aviation Liaison Agent ...
Breaking Biology News(10 mins):
(Date:3/29/2017)... ... March 29, 2017 , ... Cancer ... exhibiting in booth 513 at the Association of Community Cancer Centers (ACCC) 43rd ... 29-31. , CANCERSCAPE unites key stakeholders from leading national organizations to share ...
(Date:3/29/2017)... 2017 Research and Markets has announced the ... - Industry Forecast to 2025" report to their offering. ... The Global Agricultural ... 7.8% over the next decade to reach approximately $825.4 million by ... and forecasts for all the given segments on global as well ...
(Date:3/29/2017)... MO , March 29, 2017 /PRNewswire/ - The ... its partners Nordion, a business of Sterigenics International, and ... (LAR) has been submitted to the U.S. Nuclear Regulatory ... domestic U.S. production of molybdenum-99 (Mo-99). Once operational, production ... half of U.S. demand for Mo-99, which currently must ...
(Date:3/29/2017)... , Mar. 29, 2017 Research ... Biotechnology: Emerging Technologies and Global Markets" report to their ... ... next generation DNA sequencing, biochips, RNA interference, synthetic biology tools ... seeds; and biologicals. These technologies and products are ...
Breaking Biology Technology: