Navigation Links
Middle school students co-author research on enzyme for activating promising disease-fighters
Date:7/28/2010

Grown-ups aren't the only ones making exciting scientific discoveries these days. Two middle school students from Wisconsin joined a team of scientists who are reporting the first glimpse of the innermost structure of a key bacterial enzyme. It helps activate certain antibiotics and anti-cancer agents so that those substances do their job. Their study appears in ACS' weekly journal Biochemistry. The student co-authors of the study are from Edgewood Campus Middle School in Madison and participated in Project CRYSTAL, a special program that provides middle school students with hands-on laboratory experience.

In the report, study leader Hazel Holden and colleagues note intense scientific interest in a chemical process called methylation, which increases the activity of DNA, proteins, and other substances in the body by transferring methyl (CH3) groups to them. Special enzymes called methyltransferases make methylation possible, and these proteins are very important in a myriad of key biological processes.

Holden and colleagues studied a bacterial methyltransferase involved in the production of tetronitrose, a component of the promising anti-cancer agent, tetrocarcin, and the antibiotic kijanimicin. The methyltransferase seems to play a key role in activating these disease-fighters. The scientists identified the 3D structure of this methyltransferase, a key step in determining how it works and how it might be modified for potential use in medicine.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert  

Page: 1

Related biology news :

1. Why your boss is white, middle-class and a show-off
2. Exercise increases brain growth factor and receptors, prevents stem cell drop in middle age
3. Study says middle class coral reef fish feel the economic squeeze
4. Many middle-aged and older Americans not getting adequate nutrition
5. UT multimedia program increases middle school interest in science
6. Overweight middle-aged women cut chances of enjoying healthy old age
7. Color My Pyramid nutrition education program battles obesity in DC schools
8. identiMetrics & BIO-key(R) Provide Biometric Finger Scanning for School Food Service Nationwide
9. NJIT sustainability expert to discuss high performance schools at seminar
10. Students eat more whole grains when its gradually added to school lunch
11. Eliminating soda from school diets does not affect overall consumption
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Middle school students co-author research on enzyme for activating promising disease-fighters
(Date:8/23/2017)... ARMONK, N.Y. , Aug. 23, 2017  The general public,s help ... the human microbiome—the bacteria that live in and on the human body ... ... bacteria in the human microbiome, starting with the gut. The project's goal ... in disease. Photo credit: IBM ...
(Date:8/15/2017)... , Aug. 15 2017   ivWatch LLC , a ... intravenous (IV) therapy, today announced receipt of its ISO 13485 Certification, ... by the International Organization for Standardization (ISO®). ... ivWatch Model 400 Continuous Monitoring device for the early ... "This is an ...
(Date:7/20/2017)... WASHINGTON , July 20, 2017 Delta (NYSE: ... to board any Delta aircraft at Reagan Washington National Airport (DCA). ... Delta launches biometrics ... Delta,s ... Delta Sky Club is now integrated into the boarding process to ...
Breaking Biology News(10 mins):
(Date:9/25/2017)... ... ... Throughout the month of October, consumers will see thousands of their favorite ... industry expert David Carter is available to explain why so many leading brands and ... demand for non-GMO foods and beverages is gathering momentum, as consumers want to know ...
(Date:9/25/2017)... ... September 25, 2017 , ... Comprehend, ... presentations and demonstrations at SCDM 2017, held September 24-27, 2017 in Orlando. ... and CRO partners for more automated capabilities across evolving data, Comprehend delivers ...
(Date:9/22/2017)... (PRWEB) , ... September 22, 2017 , ... ... venous leg ulcers is now being assessed in clinical trials in the United ... please talk to your nurse or physician or find your nearest participating clinic ...
(Date:9/21/2017)... ... September 21, 2017 , ... Executives and subject ... most progressive pharma and biotech organizations to do more clinical trials will share ... events in Q4. , DrugDev will demonstrate DrugDev Spark™, the world’s first unified ...
Breaking Biology Technology: