From water quality studies to genetic counseling, the acquisition of a DNA sequencer by Mercyhurst University marks an unprecedented opportunity to accelerate biological and medical research in the region.
Thanks to a $125,000 grant from the George I. Alden Trust and a $10,000 award from the Samuel P. Black Family Fund of the Erie Community Foundation, the Mercyhurst Biology Department has purchased an Illumina MiSeq DNA sequencing machine, which will be used for a variety of university-driven research projects, among them the ongoing investigation into bacterial and viral pathogens in the recreational waters of Lake Erie at Presque Isle State Park, said Biology Department Chair Steven Mauro, Ph.D., who wrote the grant proposal.
The DNA sequencer is a multi-faceted machine that allows for rapid and robust amplification of DNA sequences from any organism. For example, a single run of the machine would identify more than one million different bacterial or viral species in a gram of soil or drop of water. With that kind of power and speed, Mauro said, the applications are numerous and multidisciplinary in scope, spanning the fields of medicine, agriculture, aquaculture, forensic science and bioterrorism.
He said crime labs use DNA sequencing to analyze evidence from a crime scene to provide a definitive DNA fingerprint of a potential suspect. Health care centers use it in disease detection and in genetic counseling.
DNA sequencing technology of this caliber does not exist in the Erie region, Mauro said, necessitating that local universities, hospitals, environmental and other research-based organizations outsource their work to DNA sequencing companies. Mercyhurst, he said, intends to share its new resource with local institutions: free of charge in some instances, student training, for example; and, in other cases, through contract services.
"The significance of Mercyhurst obtaining this kind of equipment is that it
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