Navigation Links
Men unaware of their cancer risk when female relatives test positive for BRCA mutation
Date:12/14/2007

Men whose mothers, sisters or daughters test positive for a cancer-causing gene mutation also have an increased risk of developing the disease but are unaware of that risk. That is the conclusion of a study at Fox Chase Cancer Center exploring how families communicate genetic test results.

Like their female relatives, fathers, sons or brothers can also harbor a mutation in the BRCA 1 or 2 genes. Male carriers of these mutations, more commonly called the breast cancer genes, face a 14 percent lifetime risk of developing prostate cancer as well as a 6 percent lifetime risk of developing breast cancer

Despite these health implications, we have found a lack of understanding of genetic test results among men in these families, said Mary B. Daly, M.D., Ph.D., senior vice president for population science at Fox Chase and lead author of the new research presented at the San Antonio Breast Cancer Symposium today.

Daly and her colleagues interviewed 24 men, each with a first-degree female relative who tested positive for having a BRCA1 or BRCA2 mutation. The women reported telling the results of their genetic test result to the male relative in the study, though only 18 of the men remember receiving the results.

Daly said what they learned demonstrates a level of cognitive and emotional distance that men experience from the genetic testing process.

Nearly half of the men (seven) who remembered receiving results did not believe that the test results increased their own risk of cancer. Only five (28 percent) could correctly identify their chance of being a mutation carrier.

We devote a significant amount of time learning how best to communicate genetic test results to women, but this study shows we also need to help them communicate the information to their male family members who may be impacted by the test results, concluded Daly.

Fourteen of the 18 men who recalled receiving the results expressed some level of concern about the meani
'/>"/>

Contact: Karen Mallet
karen.mallet@fccc.edu
215-514-9751
Fox Chase Cancer Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. ESF EURYI award winner aims to stop cancer cells reading their own DNA
2. Elephantnose fish see with their chin
3. Flies can turn off their immune response
4. UCR plant cell biologist to study how plant stem cells maintain and change their identity
5. Species still have more viable offspring if they can choose their best mate
6. Spatial patterns in tropical forests can help to understand their high biodiversity
7. Clever plants chat over their own network
8. Saltwater crocodiles can find their way home
9. Doctors learn to control their own brains pain responses to better treat patients
10. Sea cucumbers fast track organ regrowth by healing their wounds
11. Scientists uncover how hormones achieve their effects
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... hundred births, Down syndrome - or trisomy 21 - ... It results from a chromosomal abnormality where cells of ... (1% of the human genome). A study conducted by ... Genetic Medicine and Development at the University of Geneva ... shed light on how the extra chromosome 21 upsets ...
(Date:4/17/2014)... Clemson professor Rajendra Singh Thursday as a "Champion ... expand solar deployment in the residential, commercial and ... Professor of Electrical and Computer Engineering and director ... a local hero leading the charge across the ... solar power and driving policy changes at the ...
(Date:4/17/2014)... such as heart disease, epilepsy and pain, making them ... is still much scientists do not know about the ... into the structure of sodium channels and, specifically, one ... responsible for ,fine-tuning, the activity of the channel. The ... the Journal of Biological Chemistry . , Nerves ...
Breaking Biology News(10 mins):Trisomy 21: How an extra little chromosome throws the entire genome off balance 2Trisomy 21: How an extra little chromosome throws the entire genome off balance 3White House honors Clemson professor as 'Champion of Change' for solar deployment 2Structure of sodium channels different than previously believed 2
... AWRE ), a leading supplier of broadband technology and biometrics ... 30, 2010.   Revenues for the third quarter of ... million in the same quarter last year. Net income for the ... These results compared to a net loss of $1.1 million, or ...
... BOSTON The discovery that a protein called Rictor plays ... AKT oncogene could provide scientists with a new molecular target ... September 2010 issue of the journal Molecular Cell , ... Medical Center (BIDMC). The oncogenic cousin, known as ...
... Nanomedicine Center for Nucleoprotein Machines has received an award ... its renewal by the National Institutes of Health (NIH). ... of a clinically viable gene correction technology for single-gene ... disease. Sickle cell disease is a genetic condition ...
Cached Biology News:Aware, Inc. Reports Third Quarter 2010 Financial Results 2Aware, Inc. Reports Third Quarter 2010 Financial Results 3Aware, Inc. Reports Third Quarter 2010 Financial Results 4Aware, Inc. Reports Third Quarter 2010 Financial Results 5Rictor protein offers scientists a new molecular target for cancer therapies 2NIH renews Nanomedicine Center focused on treating single-gene disorders for $16.1 million 2NIH renews Nanomedicine Center focused on treating single-gene disorders for $16.1 million 3NIH renews Nanomedicine Center focused on treating single-gene disorders for $16.1 million 4
(Date:1/14/2014)... EquitiesIQ, a leading informational research provider, has ... an emerging biomedical company acquiring, developing, manufacturing, and marketing ... Free report download: http://equitiesiq.com/reports/alliqua/ , In late ... and Board, which launched the company’s new strategy to ...
(Date:1/14/2014)... iLab Solutions, the leader in core facility ... of Product Strategy. In this role, Michelle will work with ... guide in the development of iLab products. Her main goal ... benefit to the scientific community by offering the most advanced, ...
(Date:1/14/2014)... January 14, 2014 Global Record ... innovative information technology solutions for patients, physicians, the ... stakeholders, announced today the signing of a three-year ... and Drug Administration (FDA). This initiative is ...
(Date:1/14/2014)... January 14, 2014 Kerr Corporation, a leading ... and additional how-to information about dual arch impressions on its ... Dual Arch Impressions,” the blog entry serves up a list ... houses a step-by-step demonstration by Dr. David Little as he ...
Breaking Biology Technology:EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2
... 2011 GeoVax Labs, Inc. (OTCQB/OTCBB: GOVX), ... HIV/AIDS vaccines, announced today the opening of a third ... vaccine.  The Los Angeles-based AIDS Research Alliance (ARA) will ... site team: the AIDS Research Consortium of Atlanta and ...
... to detect the levels of vitamin B12 using your breath, ... help to avoid the potentially fatal symptoms of B12 deficiency. ... in IOP Publishing,s Journal of Breath Research , researchers ... accurately measure vitamin B12. Vitamin B12 deficiency is ...
... 2011 Veredus Laboratories, a leading provider of molecular ... STM ), today announced the successful development and ... to detect 10 to 12 food-borne pathogens in one ... (E. coli) responsible for the recent severe food poisoning ...
Cached Biology Technology:GeoVax Initiates Third Site For Therapeutic Testing of Its HIV Vaccine 2GeoVax Initiates Third Site For Therapeutic Testing of Its HIV Vaccine 3GeoVax Initiates Third Site For Therapeutic Testing of Its HIV Vaccine 4A breath of fresh air for detecting vitamin B12 deficiency 2Veredus Laboratories Develops Lab-on-Chip Solution to Detect and Differentiate Several Food-Borne Pathogens, Including Escherichia coli (E. coli) 2Veredus Laboratories Develops Lab-on-Chip Solution to Detect and Differentiate Several Food-Borne Pathogens, Including Escherichia coli (E. coli) 3Veredus Laboratories Develops Lab-on-Chip Solution to Detect and Differentiate Several Food-Borne Pathogens, Including Escherichia coli (E. coli) 4
... A direct, simple approach to ... well surface of an EIA ... maintains its integrity and availability ... dry, room temperature conditions ...
AC input: 230 V...
... lyophilization stabilizer is designed to stabilize ... for long-term storage. There are ... It is a convenient 10 ... and is superior to other traditional ...
... Freedom EVO Clinical is Tecans open platform ... enhance quality, safety and performance in the ... is provided by flexible barcode reading and ... mention that the system complies with the ...
Biology Products: