Navigation Links
Mechanisms involved in resistance to the bacteria Salmonella studied in a Ph.D. thesis
Date:2/6/2013

This press release is available in Spanish.

In their natural environment bacteria develop by forming communities of micro-organisms called biofilms that afford them greater resistance. These biofilms on farms and premises where food is processed lead to considerable economic losses besides being a potential source of contamination and transmission of the pathogen. In her PhD thesis,Violeta Zorraquino-Salvo has studied a specific protein type that activates the formation of biofilm in Salmonella and regulates bacterial motility. "Having a better idea of the mechanisms involved in these processes will help to design new, more effective strategies for preventing the formation of biofilm and its potential harm in the clinical, food and industrial ambit," points out the researcher.

Two decades ago it was discovered that a small molecule (the so-called c-di-GMP) could on its own hamper motility and activate the formation of biofilm. "This molecule is part of a signal transduction system: there are different sensory membranes on the membrane of the bacteria that pick up stimuli from the outside and transduce them into different intracellular levels of c-di-GMP, thus regulating different biological processes like biofilm formation. "In the first part of her thesis Zorraquino removed all the sensory proteins from the Salmonella's genome."We created a mutant Salmonella incapable of picking up stimuli from the medium in which it lives and therefore of producing biofilm under any circumstances. "After that, each sensory protein was inserted one by one to be able to analyse, under different ambient conditions, how each one contributed to the formation of biofilm. "We showed that under each condition tested, only some proteins are active, so each one is most likely responsible for the formation of biofilm whena given condition is present."<
'/>"/>

Contact: Oihane Lakar Iraizoz
o.lakar@elhuyar.com
34-943-363-040
Elhuyar Fundazioa
Source:Eurekalert

Page: 1 2

Related biology news :

1. FASEB SRC announces: Molecular Mechanisms & Physiological Consequences of Protein Aggregation
2. FASEB SRC announces conference registration open for: Neural Mechanisms in Cardiovascular Regulation
3. FASEB SRC announces conference registration open for: Mechanisms in Plant Development Conference
4. X-rays reveal the self-defence mechanisms of bacteria
5. Mechanisms for a beneficial effect of moderate alcohol consumption on osteoporosis in women
6. Researchers identify mechanisms that allow embryonic stem cells to become any cell in the human body
7. Force of nature: Defining the mechanical mechanisms in living cells
8. Symposium: Protein-Folding Diseases: Models & Mechanisms
9. Discovery of mechanisms predicting response to new treatments in colon cancer
10. UF receives $1 million from Keck Foundation to study mechanisms of inherited disease
11. New insight into mechanisms behind autoimmune diseases suggests a potential therapy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... non-indigenous women in Queensland, Australia, is closing, however indigenous ... preventable causes, find researchers in a new study published ... of Obstetrics and Gynaecology ( BJOG ). , ... Data Collection and looked at 881,211 singleton births from ... in stillbirth rates over time among indigenous (Australian Aboriginal ...
(Date:9/2/2014)... blogs: Earthquake rupture through a U.S. suburb , ... California Davis in the hours and days after the ... understand why the earthquake caused so much damage in ... Earth blog, hosted by the American Geophysical Union. ... Rovers: The Next Places to Direct Our Curiosity ...
(Date:9/2/2014)... 3, The Field Museum will present the prestigious Parker/Gentry ... his commitment to biodiversity conservation awareness. The Parker/Gentry Award ... outstanding individual, team or organization whose efforts have had ... heritage and whose actions can serve as a model ... Mongabay.com, an environmental science and conservation news website that ...
Breaking Biology News(10 mins):Stillbirth gap closing between indigenous and non-indigenous women, shows Australian study 2Stillbirth gap closing between indigenous and non-indigenous women, shows Australian study 3This week From AGU: California earthquake, future Mars rovers, models underestimate ozone 2
... and smoke forecasting models are useful tools to help ... in areas at risk from forest fire smoke, according ... Brauer shares his insight into the health impacts ... them today at the American Association for the Advancement ...
... This press release is available in French . ... are lots of new ideas out there for giving you extra ... good ideas may never make it to market. Researchers ... a way to enrich milk with docosahexaeonic acid (DHA)an essential nutrient ...
... An international team from the Nippon Foundation-University of British ... of life in the world,s oceans, allowing scientists and ... the state of life in the oceans of ... factors impacting our oceans climate change, human activity ...
Cached Biology News:As climate change increases forest fires, smoke forecasting could help protect public health 2Window into world's future oceans unveiled by NF-UBC Nereus team 2Window into world's future oceans unveiled by NF-UBC Nereus team 3
(Date:9/2/2014)... September 02, 2014 Opertech Bio, ... highly efficient, cost effective approach to sensory evaluation, ... 8,820,265 by the U.S. Patent and Trademark Office, ... , “Opertech’s taste evaluation technology called ... automated high throughput system for rapid characterization of ...
(Date:9/2/2014)... , Sept. 2, 2014  Xencor, Inc. (NASDAQ: ... developing engineered monoclonal antibodies for the treatment of ... today announced the appointment of Debra Zack ... the appointment of Lloyd Rowland , senior ... "Debra,s expertise in biologics clinical ...
(Date:9/2/2014)... ROCKVILLE, Md. , Sept. 2, 2014 /PRNewswire/ ... of novel anti-infective biologic and drug candidates targeting ... announced today positive results from its final preclinical ... Drug Administration (FDA) guidance, this bridging study was ... product candidate designed to prevent the devastating effects ...
(Date:9/2/2014)... Mount, NC (PRWEB) September 02, 2014 ... establishment of its 11th clinical research site: PMG Research ... assumed ownership and operation of the clinical research department ... further expanding PMG’s presence in eastern North Carolina. This ... patients. For the patients in Rocky Mount and the ...
Breaking Biology Technology:Opertech Bio Receives U.S. Patent for High-Throughput Taste Evaluation Technology 2Xencor Appoints Debra Zack, M.D., Ph.D., Vice President, Clinical Development and Lloyd Rowland, Senior Vice President, Chief Compliance Officer and General Counsel 2Xencor Appoints Debra Zack, M.D., Ph.D., Vice President, Clinical Development and Lloyd Rowland, Senior Vice President, Chief Compliance Officer and General Counsel 3Synthetic Biologics to Initiate Clinical Trials of SYN-004 in 4Q 2014 to Prevent Potentially Deadly C. difficile Infections 2Synthetic Biologics to Initiate Clinical Trials of SYN-004 in 4Q 2014 to Prevent Potentially Deadly C. difficile Infections 3Synthetic Biologics to Initiate Clinical Trials of SYN-004 in 4Q 2014 to Prevent Potentially Deadly C. difficile Infections 4Synthetic Biologics to Initiate Clinical Trials of SYN-004 in 4Q 2014 to Prevent Potentially Deadly C. difficile Infections 5PMG Research Announces the Formation of its Eleventh Site 2PMG Research Announces the Formation of its Eleventh Site 3
... 25 BN,ImmunoTherapeutics, Inc. announced today that the ... licensed from the National Institutes of,Health (NIH) is ... the,excellent safety and efficacy results previously reported, will ... on February 26-28, 2009 in,Orlando, Florida. , ...
... 25 /PRNewswire-Asia-FirstCall/ -- 3SBio Inc. (Nasdaq:, SSRX ... researching,developing, manufacturing and marketing biopharmaceutical products, today,announced that ... quarter and,full year ended December 31, 2008 after ... , Following the earnings ...
... Cerimon Pharmaceuticals, Inc., announced today the Company has enrolled ... patch Phase III program. The program consists of ... Cerimon,s diclofenac patch. The studies will assess the ... placebo for the treatment of acute pain caused by ...
Cached Biology Technology:BN ImmunoTherapeutics Reports Further Data on PROSTVAC(TM) 2BN ImmunoTherapeutics Reports Further Data on PROSTVAC(TM) 33SBio Inc. to Report 2008 Fourth Quarter and Full Year Earnings on March 11, 2009 2Cerimon Pharmaceuticals Initiates Phase III Clinical Studies to Evaluate Its Topical Diclofenac Sodium Patch for Mild-to-Moderate Pain 2
... Neutralizing synthetic peptide for OPA1-01009, OPEP-01009 is a 16 ... from human DNA fragmentation factor (DFF). The sequence of ... - P - K - S - V - K ... - S - P - R - K(18). ...
... intended for laboratory research use only. ... buffered formalin and embedded in paraffin. ... certified pathologists. Tissue cores were removed ... a new recipient paraffin block, in an ...
... High Throughput Processing of Microarrays Using the ... Frame multiple slide plate is designed to ... corresponding multi-well incubation chambers in a microplate ... The footprint dimensions meet the standards recommended ...
fully automated system for the processing of microarrays on microscope slides...
Biology Products: