Navigation Links
MIT: Mimicking the brain, in silicon
Date:11/15/2011

h biological systems. This could be useful in enabling communication between neural prosthetic devices such as artificial retinas and the brain. Further down the road, these chips could also become building blocks for artificial intelligence devices, Poon says.

Debate resolved

The MIT researchers have already used their chip to propose a resolution to a longstanding debate over how LTD occurs.

One theory holds that LTD and LTP depend on the frequency of action potentials stimulated in the postsynaptic cell, while a more recent theory suggests that they depend on the timing of the action potentials' arrival at the synapse.

Both require the involvement of ion channels known as NMDA receptors, which detect postsynaptic activation. Recently, it has been theorized that both models could be unified if there were a second type of receptor involved in detecting that activity. One candidate for that second receptor is the endo-cannabinoid receptor.

Endo-cannabinoids, similar in structure to marijuana, are produced in the brain and are involved in many functions, including appetite, pain sensation and memory. Some neuroscientists had theorized that endo-cannabinoids produced in the postsynaptic cell are released into the synapse, where they activate presynaptic endo-cannabinoid receptors. If NMDA receptors are active at the same time, LTD occurs.

When the researchers included on their chip transistors that model endo-cannabinoid receptors, they were able to accurately simulate both LTD and LTP. Although previous experiments supported this theory, until now, "nobody had put all this together and demonstrated computationally that indeed this works, and this is how it works," Poon says.


'/>"/>

Contact: Caroline McCall
cmccall5@mit.edu
Massachusetts Institute of Technology
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Some vocal-mimicking animals, particularly parrots, can move to a musical beat
2. Wildlife Conservation Society finds wild cat mimicking monkey calls
3. Boston Univ., Veterans Affairs find sports brain trauma may cause disease mimicking ALS
4. Mimicking nature, water-based artificial leaf produces electricity
5. Mimicking nature at the nanoscale: Selective transport across a biomimetic nanopore
6. Changing fine structure constant, packing spheres tighter, and mimicking complex birdsongs
7. Social interactions can alter gene expression in the brain, and vice versa
8. Knee injuries may start with strain on the brain, not the muscles
9. Experimental drug shows promise against brain, prostate cancers
10. UR study reveals chemos toxicity to brain, possible treatment
11. Regular aerobic exercise is good for the brain, Pitt team says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... a cost-effectiveness analysis of commercial diet programs and pills, ... the best value for the money. The Jenny Craig ... the most expensive option tested, according to researchers at ... The findings, published in the June issue of the ... health and weight-loss benefits per dollar spent as insurance ...
(Date:7/22/2014)... MSN, APRN, PMHCNS-BC, CNE, Assistant Professor of Clinical ... School of Nursing, contributed samples used in a ... with schizophrenia and also suggesting a possible link ... Biological insights from 108 schizophrenia-associated genetic loci, was ... , available at http://www.nature.com/nature/journal/vaop/ncurrent/full/nature13595.html., ...
(Date:7/22/2014)... 22, 2014 NXT-ID, Inc., (NXTD: OTCQB) a biometric ... announces its next generation smart wallet, Wocket™, will be featured ... show that airs on the History Channel, FYI ... regularly features top technology products and services. The ... History Channel (6:00-6:30am ET/PT) and the FYI Network ...
Breaking Biology News(10 mins):Study compares cost-effectiveness of weight-loss programs and drugs 2Study compares cost-effectiveness of weight-loss programs and drugs 3LSUHSC contributes to work identifying new DNA regions associated with schizophrenia 2NXT-ID's Next Generation Wocket Smart Wallet to be Featured on NewsWatch, Airing on History Channel, FYI Network and ION Network 2NXT-ID's Next Generation Wocket Smart Wallet to be Featured on NewsWatch, Airing on History Channel, FYI Network and ION Network 3
... Indiana University study found that strengthening inspiratory muscles by ... the amount of oxygen these same breathing muscles required ... muscles. Louise Turner, a researcher in the Department ... an endurance activity, such as running, swimming or cycling ...
... to all living things can make hibernating marmots hungry ... obesity and eating disorders, according to a new study ... appears in the current issue of the Journal ... at http://jeb.biologists.org/cgi/reprint/213/12/2031 . Professor Greg Florant discovered ...
... dish coating could overcome a major challenge to the ... of Michigan researchers. Under today,s regulations, current stem ... the cells have been grown on animal-based substances that ... components create issues with the FDA (the U.S. Food ...
Cached Biology News:Inspiratory muscle training and endurance sport performance 2Marmots can teach us about obesity 2New culture dish could advance human embryonic stem cell research 2
(Date:7/22/2014)... SHENZHEN , Kina, 22. juli 2014 ... Tech), et datterselskab af BGI, verdens største genomics-organisation, ... whole exome-sekvenseringstjeneste baseret på Complete Genomics brancheførende platform. ... branchen for at levere patenterede sekvenseringsteknologier med 99,999 ... varianter, blev købt af BGI i 2013. Mere ...
(Date:7/22/2014)... Urdorf, Switzerland (PRWEB) July 22, 2014 ... TDLs are becoming an increasingly common sight. The ... means they are now well- established as a ... and low maintenance has made them the gas ... installation locations and conditions encountered in some processes ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 Holomic ... with the debut of its fluorescent immunoassay reader, ... Chemistry (AACC) meeting in Chicago, July 28-31, 2014. ... top versions, the HRDR-300 is a highly sensitive, ... to analyze fluorescent lateral flow immunoassays with high ...
(Date:7/21/2014)... 21, 2014 Lawrence Livermore ... Board (WIB) and Las Positas College (LPC) recently ... education and hands-on training for veterans, officials recently ... at Las Positas is designed to help ... engineering technician careers, and establishes a pipeline of ...
Breaking Biology Technology:BGI Tech lancerer Human Whole Exome-sekvenseringstjeneste på Complete Genomics avancerede platform 2METTLER TOLEDO Shows How Tunable Diode Lasers (TDLs) Can Be Installed Where No TDLs Have Gone Before 2Holomic to Debut HRDR-300 Fluorescent Immunoassay Reader at the AACC 2014 2Engineering Program Established for Veterans 2Engineering Program Established for Veterans 3
... Analysts are ... only 308 job cuts announced in the pharmaceutical industry in March, 27,000 new health care ... be correct. , ... -- If the absence of bad news can be considered good news, then it is good ...
... Encyclopedia ... Amazon.com , ... (PRWEB) April 15, 2010 -- The preponderance of autism research shows no correlation between vaccines ... encyK Resource for Parents & Professionals . By retracting the article that first reported the ...
... , ... by Behavioral HealthCare Program to streamline data reporting and ad hoc analysis , ... (PRWEB) April 13, 2010 ... utilizes a complex relational database for storing its data. The program manages behavioral ...
Cached Biology Technology:The MedZilla Report for April 2010 - Pharma Layoffs Drop Below 400 in March; Health Care Adds Another 27,000 Jobs 2The MedZilla Report for April 2010 - Pharma Layoffs Drop Below 400 in March; Health Care Adds Another 27,000 Jobs 3Research in Autism Encyclopedia Shows No Link to Children With Autism, Supports Lancet Retraction 2Maine Medical Center Chooses Business Intelligence Solution from Rapid Insight Inc. 2
CleanCut agarose is used to prepare genomic DNA plugs for use in pulsed field gel electrophoresis (PFGE) applications. Supplied as a 12 ml solution of 2% agarose....
... 96 PW is an intelligent full microplate washer ... wells simultaneously. This instrument gives you the best ... washing efficiency , Performance ,Separate ... excellent wash efficiency. A dispense precision of better ...
... for cell culture scale-up, these culture chambers ... - 10 9 range and are ... spinner flasks. • High mechanical • strength ... prior to shipping • Certified nonpyrogenic and ...
... in immunostaining ,This solution has effect on ... get clearer signal than the one obtained ... amount of secondary antibody used and exposure ... can have images with high S/N ratio ...
Biology Products: