Navigation Links
MGH researcher Gary Ruvkun named a co-recipient of the Lasker Award
Date:9/13/2008

Massachusetts General Hospital (MGH) and Harvard Medical School investigator Gary Ruvkun, PhD, is one of three co-recipients of the 2008 Lasker Award for Basic Medical Research. Presented by the Albert and Mary Lasker Foundation, the Lasker Awards are often considered the American version of the Nobel Prize, and many Lasker recipients have gone on to win the Nobel. The award will be presented in New York on Friday, Sept. 26.

Ruvkun and his co-recipients Victor Ambros, PhD, of the University of Massachusetts Medical School and David Baulcombe, PhD, FRS, University of Cambridge in the U.K. are being honored for discovering that tiny molecules of RNA can control the activity of critical genes in animals and plants. Instead of being translated into proteins as messenger RNAs are, single-stranded microRNAs bind to regulatory segments of their target genes' RNA and block gene expression. Current knowledge suggests that microRNAs may control one third of human protein-coding genes.

In the early 1980s Ruvkun and Ambros were both fellows in the Massachusetts Institute of Technology laboratory of Robert Horvitz, PhD, investigating genes that control development in the C. elegans roundworm. They worked together to isolate a gene called lin-14 that operates in concert with a gene called lin-4 to regulate the worms' transition through key developmental stages.

As the two researchers established their own laboratories Ruvkun in the MGH Department of Molecular Biology and Ambros at Harvard they continued collaborating to uncover how the two regulatory genes interacted and made some surprising discoveries. Lin-4 did not block the activity of lin-14 through the protein it coded for but in a manner never seen before by direct interaction between the two genes' RNA strands. These critical RNA molecules also appeared to be extremely small, around 20 nucleotides long. In the meantime Baulcombe was pursuing similar research in plants. His
'/>"/>

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Curbing coal emissions alone might avert climate danger, say researchers
2. Researchers develop nano-sized cargo ships to target and destroy tumors
3. Gap junction protein vital to successful pregnancy, researchers find
4. Cortisol and fatty liver: Researchers find cause of severe metabolic disorders
5. Researchers seeking to identify Alzheimers risk focus on specific blood biomarker
6. Childrens National researcher receives ACCP Distinguished Investigator Award
7. New once-a-week treatment for type 2 diabetes developed by Mount Sinai researcher
8. ISU researchers help map first plant-parasitic nematode genome sequence
9. Collaboration between researchers yields more comprehensive portrait of brain cancer
10. Tel Aviv University researchers create new stem cell screening tool
11. NYU Cancer Institute researcher among first NIH EUREKA award recipients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/16/2015)... 2015 Fingerprint Cards has received an ... the company,s portfolio from one of its module partners in ... take place during the third quarter 2015. The sensors will ... . Jörgen Lantto, CEO of FPC, comments: " ... growing interest from smartphone OEMs in integrating touch fingerprint sensors ...
(Date:6/15/2015)... , Jun. 15, 2015 NXT-ID, Inc. (NASDAQ: ... focused on the growing mobile commerce market, announces that its ... showcased to media at Digital Experience! @ NYC June 18th. ... showcase of the latest innovation in technology to over 300 ... be held at the Metropolitan Pavilion in New ...
(Date:6/9/2015)... June 9, 2015   MedNet Solutions , an ... spectrum of clinical research, will be providing demonstrations of ... at the 2015 Drug Information Association (DIA) Annual Meeting ... 15-17.  These presentations will include previews of many exciting ... the upcoming iMedNet 2015 Feature 1 Release. ...
Breaking Biology News(10 mins):FPC Receives Order for Touch Fingerprint Sensors of 375 MSEK 2Wocket Smart Wallet Exhibiting at Pepcom Digital Experience! @ NYC June 18th 2Wocket Smart Wallet Exhibiting at Pepcom Digital Experience! @ NYC June 18th 3MedNet To Provide Sneak Peeks Of Its iMedNet "2015 Feature 1 Release" At The DIA Annual Meeting 2MedNet To Provide Sneak Peeks Of Its iMedNet "2015 Feature 1 Release" At The DIA Annual Meeting 3
... is no longer necessary for growing potatoes, at least ... is undertaking a research project, together with Neiker-Tecnalia (the ... tubers in air, by means of a novel system ... a pioneering experience in Spain, given that never before ...
... size of the Gulf oil spill, the possible risks ... fate of an endangered fish in the Colorado River ... Science Journalism Awards. The awards, administered by the ... their inception in 1945, go to professional journalists for ...
... MADISON, WI November 8, 2010 -- Conversion of sorghum ... fuel sources. Researchers at Iowa State University examined 12 varieties ... The experiment was designed to test the efficiency of double ... The author of the report, Ben Goff, found ...
Cached Biology News:Newco produces seed potatoes in the open air 2Newco produces seed potatoes in the open air 3Winners of 2010 AAAS Kavli Science Journalism Awards 2Winners of 2010 AAAS Kavli Science Journalism Awards 3Winners of 2010 AAAS Kavli Science Journalism Awards 4Winners of 2010 AAAS Kavli Science Journalism Awards 5Winners of 2010 AAAS Kavli Science Journalism Awards 6Winners of 2010 AAAS Kavli Science Journalism Awards 7Winners of 2010 AAAS Kavli Science Journalism Awards 8Growing sorghum for biofuel 2
(Date:6/29/2015)... Manhattan, KS (PRWEB) , ... June 29, 2015 ... ... US PATENT 7736892 B2. Under the terms of the agreement, MediVet will acquire ... Matrix Stem Cells (UCMSCs). MB-007 is currently in pre-clinical development as a potential ...
(Date:6/29/2015)... , June 29, 2015  MiMedx Group, Inc. (NASDAQ: ... human amniotic tissue and patent-protected processes to develop and ... Surgical, Orthopedic, Spine, Sports Medicine, Ophthalmic and Dental sectors ... H. "Pete" Petit, has been awarded the Lifetime Achievement ... Southeast Program. The Entrepreneur Of The ...
(Date:6/29/2015)... SOUTH SAN FRANCISCO, Calif. , June 29, 2015 ... a molecular diagnostics company pioneering the field of molecular ... the Bay Area News Group,s prestigious Top Workplaces list ... group selects Top Workplace winners based solely on an ... "We are humbled and honored that the degree to ...
(Date:6/26/2015)... , June 26, 2015   ... ), a pet therapeutics company focused on ... biopharmaceutical products for companion animals, today announced ... study of capromorelin (AT-002), the company,s innovative ... is a small molecule that mimics ghrelin, ...
Breaking Biology Technology:MediVet Biologics Acquires Exclusive Patent License from Kansas State University 2MediVet Biologics Acquires Exclusive Patent License from Kansas State University 3EY Entrepreneur Of The Year Program Recognizes Pete Petit, The Chairman & CEO of MiMedx 2Veracyte Named a 2015 "Top Workplace" in the San Francisco Bay Area 2Veracyte Named a 2015 "Top Workplace" in the San Francisco Bay Area 3Aratana Therapeutics Announces Positive Pivotal Results for AT-002 2Aratana Therapeutics Announces Positive Pivotal Results for AT-002 3Aratana Therapeutics Announces Positive Pivotal Results for AT-002 4Aratana Therapeutics Announces Positive Pivotal Results for AT-002 5
... , , AUSTIN, Texas, Jan. 7 Bender Consulting, ... key trends and merger and acquisition (M&A) related activity that ... sector for 2010. Bender Consulting combines proven industry experts and ... Tech, Energy and Bio Tech clients. The talent at Bender ...
... , FT. LAUDERDALE, Fla. , Jan. 15 ... Fund to provide further investment for the company,s growth in the ... is how CEO Chris Hamilton views this decision. "Funding ... and ultimately reducing Carbon Emissions feature so highly on the agenda ...
... , DURHAM, N.C. , Jan. 14 ... announced Wednesday the award of $44 million in ... (NAABB), a consortium including Palmer Labs, LLC , of Durham, ... Palmer Labs of its patent-pending algae technology addressing both energy and nutritional ...
Cached Biology Technology:Bender Consulting Predicts Key Trends and Merger and Acquisition Activity for the Oil & Gas Sector in 2010 2Bender Consulting Predicts Key Trends and Merger and Acquisition Activity for the Oil & Gas Sector in 2010 3InfoSpi to Create $500m Green Hedge Fund Focusing on the Carbon Credit Market 2Palmer Labs Awarded U.S. Department of Energy Funding for Algae Biofuel Research 2Palmer Labs Awarded U.S. Department of Energy Funding for Algae Biofuel Research 3Palmer Labs Awarded U.S. Department of Energy Funding for Algae Biofuel Research 4
Curcumin is an extract of turmeric root with antioxidant, anti-tumor promoter, and anti-inflammatory properties. Curcumin inhibits the induction of NOS in macrophages....
UGT1A6 (D-20)...
... is the smallest electronic pressure controller available ... Parker configured this unit specifically for the ... Used in carrier gas flow control, microfluidic ... and hydro-dynamic focusing, the OEM-EPC offers external ...
... Thrust Slide is designed for heavy duty ... limited and substantial side-loading is present. Standard ... millions of trouble-free cycles even in high ... or recirculating ball bearings , Optional corrosion ...
Biology Products: