Navigation Links
MGH researcher Gary Ruvkun named a co-recipient of the Lasker Award
Date:9/13/2008

Massachusetts General Hospital (MGH) and Harvard Medical School investigator Gary Ruvkun, PhD, is one of three co-recipients of the 2008 Lasker Award for Basic Medical Research. Presented by the Albert and Mary Lasker Foundation, the Lasker Awards are often considered the American version of the Nobel Prize, and many Lasker recipients have gone on to win the Nobel. The award will be presented in New York on Friday, Sept. 26.

Ruvkun and his co-recipients Victor Ambros, PhD, of the University of Massachusetts Medical School and David Baulcombe, PhD, FRS, University of Cambridge in the U.K. are being honored for discovering that tiny molecules of RNA can control the activity of critical genes in animals and plants. Instead of being translated into proteins as messenger RNAs are, single-stranded microRNAs bind to regulatory segments of their target genes' RNA and block gene expression. Current knowledge suggests that microRNAs may control one third of human protein-coding genes.

In the early 1980s Ruvkun and Ambros were both fellows in the Massachusetts Institute of Technology laboratory of Robert Horvitz, PhD, investigating genes that control development in the C. elegans roundworm. They worked together to isolate a gene called lin-14 that operates in concert with a gene called lin-4 to regulate the worms' transition through key developmental stages.

As the two researchers established their own laboratories Ruvkun in the MGH Department of Molecular Biology and Ambros at Harvard they continued collaborating to uncover how the two regulatory genes interacted and made some surprising discoveries. Lin-4 did not block the activity of lin-14 through the protein it coded for but in a manner never seen before by direct interaction between the two genes' RNA strands. These critical RNA molecules also appeared to be extremely small, around 20 nucleotides long. In the meantime Baulcombe was pursuing similar research in plants. His
'/>"/>

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Curbing coal emissions alone might avert climate danger, say researchers
2. Researchers develop nano-sized cargo ships to target and destroy tumors
3. Gap junction protein vital to successful pregnancy, researchers find
4. Cortisol and fatty liver: Researchers find cause of severe metabolic disorders
5. Researchers seeking to identify Alzheimers risk focus on specific blood biomarker
6. Childrens National researcher receives ACCP Distinguished Investigator Award
7. New once-a-week treatment for type 2 diabetes developed by Mount Sinai researcher
8. ISU researchers help map first plant-parasitic nematode genome sequence
9. Collaboration between researchers yields more comprehensive portrait of brain cancer
10. Tel Aviv University researchers create new stem cell screening tool
11. NYU Cancer Institute researcher among first NIH EUREKA award recipients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2015)... 2015  VOXX International Corporation (Nasdaq: VOXX ... a Definitive Agreement to purchase the assets, inclusive ... leader EyeLock through an acquiring entity.  Upon consummation ... interest in the acquiring entity. The closing of ... diligence.  Expanding on its existing supply chain and ...
(Date:8/12/2015)... , August 12, 2015 ... of mobile payment innovation and advanced biometrics technology is ... the way consumers rely on using their credit cards, ... reinventing the future for payment services led by companies ... NXTD ), :  Google, Inc. (NASDAQ: GOOG ), ...
(Date:8/10/2015)... , August 10, 2015 The latest ... offers comprehensive analysis of the global border security market ... revenues of $16.4bn in 2015. Now: Border security ... an example of the business critical issue you need to ... visiongain ,s objective analysis of how this will impact ...
Breaking Biology News(10 mins):VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 2VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 3VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 4VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 2Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 4Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 5Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 7Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 8Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 9
... Conn. , May 30, 2013 /PRNewswire-iReach/ -- ... industry leaders from around the world will convene ... detection and identification of biological threats ... http://photos.prnewswire.com/prnh/20130530/CG22485 ) The conference is organized ...
... from around the globe issued joint statements today to ... and innovation can play in the pursuit of sustainable ... threat of drug resistance in infectious agents including tuberculosis. ... leaders attending next month,s G8 Summit and other international ...
... exams might want to wait before pulling an all-night ... neurons are concerned. Carnegie Mellon University neuroscientists have discovered ... repeated exposure to a stimulus shrinks synapses. The findings ... Journal of Neuroscience . It,s well known ...
Cached Biology News:Join Leading Organizations at Biodetection Technologies 2013 in Alexandria, VA from June 18-19, 2013 2Join Leading Organizations at Biodetection Technologies 2013 in Alexandria, VA from June 18-19, 2013 3Science academies issue 'G-Science' statements to call world leaders' attention to global challenges 2Carnegie Mellon neuroscientists discover new phase of synaptic development 2
(Date:8/27/2015)... CA (PRWEB) , ... August 27, 2015 , ... ... unique opportunity for venture capital funds, investment firms and animal health companies to ... Forum have raised $160 million. Several have also received licensing agreements or distribution ...
(Date:8/27/2015)... Calif. , Aug. 27, 2015  Asterias Biotherapeutics, ... the emerging field of regenerative medicine, today announced that ... conferences in the month of September.  ... present at Rodman & Renshaw,s 17th Annual Global Investment ... PT at the St. Regis Hotel in ...
(Date:8/27/2015)... ... August 27, 2015 , ... METTLER TOLEDO's web-based EasyFinder™ ... product choices to a manageable shortlist of bench and floor scales and terminals. ... fit best with the customer’s industry and application. , Side-by-side product comparisons ...
(Date:8/26/2015)... 2015  Roka Bioscience, Inc. (NASDAQ: ROKA ), ... solutions for the detection of foodborne pathogens, today announced ... Sidoti & Company Emerging Growth Conference on September 2 ... the New York Marriott Marquis. A ... the investor relations section of Roka Bioscience,s website at ...
Breaking Biology Technology:VetStem Biopharma, Inc. Among Seventeen Companies Selected to Present at the KC Animal Health Investment Forum on September 1st 2015 2VetStem Biopharma, Inc. Among Seventeen Companies Selected to Present at the KC Animal Health Investment Forum on September 1st 2015 3Asterias Biotherapeutics to Present at Upcoming Investor Conferences 2METTLER TOLEDO Updates Online Scale Selection Tool 2
... recently released list of the top 100 IT leaders ... vice president and CIO of Church Mutual Insurance Company ... organizations, including churches as well as schools, camps and other ... , , Herman Nell, senior vice president and CIO of ...
... Technical College recently finished the first semester of ... which will soon be taught at technical colleges all ... need for security specialists. , ,MATC, one of the ... two-year degree development process down to five months. Network ...
... SBC kicked off its strategy of digital convergence on ... showing off its new home entertainment service. , ,Designed ... the service brings together satellite TV, digital video recording and ... an SBC satellite dish and DSL connection. , ,In his ...
Cached Biology Technology:Computerworld: Three Wisconsin CIOs among top 100 IT leaders 2MATCs new computer security program gears up for second semester 2MATCs new computer security program gears up for second semester 3SBC blends TV, video, music and the Internet in a new media box 2
... The DNA Engine Dyad instrument is the ... Featuring MJ's world-class thermal performance, the ... display, as well as point-and-click navigation via ... Dyad can be easily and economically expanded ...
... the Quansys Biosciences Q-Plex Array is a ... for human, mouse, and rat research. The ... quantitative ELISA-based test where 4 distinct capture ... of a 96-well plate in a defined ...
Caliper offers a wide array of standard LabChip products designed to be used in combination with our AMS 90 and LabChip 3000 microfluidic platforms....
... for 10 chips provides the chips and ... the Experion automated electrophoresis system. This kit ... 520 microliters Pro260 gel, 45 microliters Pro260 ... 400 microliters Pro260 sample buffer, and 3 ...
Biology Products: