Navigation Links
Low-cost sterilization method for cats and dogs is focus of new research project
Date:7/17/2013

WINSTON-SALEM, N.C. July 18, 2013 As an expert in molecular genetics, Colin E. Bishop, Ph.D.'s, usual role at the Wake Forest Baptist Medical Center's Institute for Regenerative Medicine is to apply the techniques of genetics and developmental biology to the regeneration of human organs.

But, with a background specifically in reproductive genetics, Bishop is also on a mission to help solve the over-population of homeless dogs and cats. Bishop has been awarded a two-year pilot grant from Michelson Prize and Grants (MPG), a division of the Found Animals Foundation, to develop a one-shot, non-surgical method for sterilizing companion animals.

According to MPG, an estimated six million to eight million cats and dogs enter U.S. shelters and three to four million of these animals are euthanized. Bishop is one of about 20 grant recipients worldwide working on developing non-surgical, single dose sterilization technology. The foundation will award a $25 million prize to the first research entity to develop a successful product.

Bishop's approach is to develop an injection to destroy particular cells in the hypothalamus, an area in the brain about the size of a pearl that controls reproduction in mammals. Because brain cells do not regenerate, it is believed that the treatment will lead to permanent sterility in the animals. Just like neutering or spaying, this method has the potential to eliminate the unwanted mating behaviors of companion animals without affecting their general health.

Specifically, the treatment aims to destroy GnRH cells in the hypothalamus that stimulate hormones that control male and female fertility. Bishop is designing a novel system for delivering a toxin to the GnRH cells. He will engineer nano-sized packages called exosomes that are generated from adult stem cells. These packages will be tagged to carry the molecular "address" of the GnRH cells, so that other cell types will not be affected. Inside
'/>"/>

Contact: Karen Richardson
krchrdsn@wakehealth.edu
336-716-4453
Wake Forest Baptist Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. Low-cost in-vitro fertilization method developed at CU may help couples in developing countries
2. Low-cost nano-biosensor to detect foodborne pathogen that causes listeriosis
3. Can algae-derived oils support large-scale, low-cost biofuels production?
4. Plants provide accurate low-cost alternative for diagnosis of West Nile Virus
5. Students create low-cost biosensor to detect contaminated water in developing nations
6. Low-cost carbon capture gets X-rayed
7. Low-cost nanosheet catalyst discovered to split hydrogen from water
8. Memorial Sloan-Kettering researchers develop new method for tracking cell signaling
9. Researchers create method to rapidly identify specific strains of illness
10. Gasification method turns forest residues to biofuel with less than a euro per liter
11. Gasification method turns forest residues to biofuel with less than a euro per litre
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/23/2014)... in their mid-thirties and forties, face a devastating ... two decades. "Mutant" protein clusters, long blamed for ... the primary focus of therapies in development by ... Prof. Gerardo Lederkremer and Dr. Julia Leitman of ... Immunology, in collaboration with Prof. Ulrich Hartl of ...
(Date:4/23/2014)... Toronto Scarborough research shows that male black widow spiders ... a rare example of mate preference by male spiders. ... Emily MacLeod and Maydianne Andrade, a professor in UTSC,s ... studies and the wild that males overwhelmingly chose to ... black widows can tell whether a potential mate is ...
(Date:4/23/2014)... source of a unique rhythmic sound, recorded for decades ... the Antarctic minke whale ( Balaenoptera bonaerensis ). First ... who thought it sounded like a duck, the bio-duck ... Southern Ocean, but its source has remained a mystery, ... of researchers deployed acoustic tags on two Antarctic minke ...
Breaking Biology News(10 mins):On the defensive 2On the defensive 3Picky male black widow spiders prefer well-fed virgins 2Scientists identify source of mysterious sound in the Southern Ocean 2Scientists identify source of mysterious sound in the Southern Ocean 3
... have uncovered a dramatic new twist in the battle against ... itself immune to a key component of the only effective ... team of TB researchers at Leicester announced a new advance ... They isolated the molecular weapons of the bacterium and are ...
... spring arrives across the country, tourists returning to beaches will ... algae that make water unfit for swimming and pose risks ... realize is that the small streams running through their neighborhoods ... feeds the algae blooms. A new study published in ...
... RIDGE, Tenn., March 12, 2008 -- Noted green energy ... this years Global Venture Challenge, a business competition and ... Ridge National Laboratory. The focus of this years ... bioenergy, energy efficiency and power generation sectors. Sridhar, ...
Cached Biology News:Scientists discover how TB 'develops invincibility' against only available treatment 2From the backyard to the ocean: New study shows streams act as key nitrogen filters 2
(Date:1/14/2014)... 2014 iLab Solutions, the leader in core ... Director of Product Strategy. In this role, Michelle will work ... to guide in the development of iLab products. Her main ... possible benefit to the scientific community by offering the most ...
(Date:1/14/2014)...  RXi Pharmaceuticals Corporation (OTCQX: RXII), a biotechnology company ... addressing major unmet medical needs using RNA-targeted technologies, ... Allowance from the United States Patent and Trademark ... for the treatment of fibrosis. The patent covers ...
(Date:1/14/2014)... 14, 2014   Kinaxis ®, provider of RapidResponse ®, ... and operations planning ( S&OP ) service, is proud to ... which will be held at the Hilton San Diego Bayfront, ... customer Elisabeth Kaszas , Director of Supply Chain at ...
(Date:1/14/2014)... CA (PRWEB) January 14, 2014 Kerr Corporation, ... 10-minute video and additional how-to information about dual arch impressions ... Restorations with Dual Arch Impressions,” the blog entry serves up ... technique and houses a step-by-step demonstration by Dr. David Little ...
Breaking Biology Technology:iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2
... hair-like blood vessels in the back of our eyes, researchers ... those that bring blood to the heart respond to air ... otherwise healthy people exposed to high levels of air pollution ... of heart disease. Previous studies linked pollution to heart ...
... An international team of researchers has succeeded in creating ... for the first time, allowing them to examine the ... the University of Leeds, the US Department of Energy,s ... Facilities Council,s Rutherford Appleton Laboratory say the breakthrough will ...
... Mass. -- Researchers at Tufts University School of Engineering have ... and two variations, using E. coli as the ... 24, 2010, issue of Chemistry and Biology, offers ... new drugs that will combat the growing incidence of antibiotic ...
Cached Biology Technology:Photos of tiny blood vessels in the eye link air pollution to heart disease 2Scientists create highly ordered artificial spin ice using nanotechnology 2Scientists create highly ordered artificial spin ice using nanotechnology 3Erythromycin A produced in E. coli for first time 2
Procollagen type I C-terminal propeptide (human, PICP)...
... in Early Drug Development with Imaging Mass ... drug compound localization data in early drug ... mass spectrometry service maps unlabeled ... so you can localize drugs and metabolites ...
... LC Sciences provides a unique new ... DNA synthesis serving diverse needs in genomics, ... applications. OligoMix is a MIXTURE of a ... sequences delivered in a single microtube. OligoMix ...
... is an automated, high-resolution protein analysis ... ProteomeLab family of products, the PA ... automated protein characterization solutions including molecular ... carbohydrate profiling and mechanisms to study ...
Biology Products: