Navigation Links
Lost frog DNA revived: Lazarus Project
Date:3/15/2013

The genome of an extinct Australian frog has been revived and reactivated by a team of scientists using sophisticated cloning technology to implant a "dead" cell nucleus into a fresh egg from another frog species.

The bizarre gastric-brooding frog, Rheobatrachus silus which uniquely swallowed its eggs, brooded its young in its stomach and gave birth through its mouth - became extinct in 1983.

But the Lazarus Project team has been able to recover cell nuclei from tissues collected in the 1970s and kept for 40 years in a conventional deep freezer. The "de-extinction" project aims to bring the frog back to life.

In repeated experiments over five years, the researchers used a laboratory technique known as somatic cell nuclear transfer. They took fresh donor eggs from the distantly related Great Barred Frog, Mixophyes fasciolatus, inactivated the egg nuclei and replaced them with dead nuclei from the extinct frog. Some of the eggs spontaneously began to divide and grow to early embryo stage a tiny ball of many living cells. Although none of the embryos survived beyond a few days, genetic tests confirmed that the dividing cells contain the genetic material from the extinct frog.

The results are yet to be published.

"We are watching Lazarus arise from the dead, step by exciting step," says the leader of the Lazarus Project team, Professor Mike Archer, of the University of New South Wales, in Sydney. "We've reactivated dead cells into living ones and revived the extinct frog's genome in the process. Now we have fresh cryo-preserved cells of the extinct frog to use in future cloning experiments.

"We're increasingly confident that the hurdles ahead are technological and not biological and that we will succeed. Importantly, we've demonstrated already the great promise this technology has as a conservation tool when hundreds of the world's amphibian species are in catastrophic decline."

The technical work was led by Dr Andrew F
'/>"/>

Contact: Deborah Smith
deborah.smith@unsw.edu.au
61-478-492-060
University of New South Wales
Source:Eurekalert  

Page: 1 2

Related biology news :

1. The large-scale EU project EU BON: Towards integration with its global counterpart GEO BON
2. Data pooling in biobanks: The BIOPOOL project
3. Meeting: Project aims to predict yield potential to help global food security
4. International biodiversity data symposium to mark the kickoff of the EU BON project
5. NSF selects OSU to lead project rejuvenating US research fleet
6. Japanese research organizations contribute to Human Brain Project
7. Climate change projected to alter Indiana bat maternity range
8. Human Brain Project funded - 1 billion euros to map the human brain
9. EU Commission selects Human Brain Project, with Israelis as partners
10. ASU partners with Life Technologies on US DHHS funded project to rapidly assess radiation dose
11. WHOI research projects awarded $5.2 million to support marine microbial research
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Lost frog DNA revived: Lazarus Project
(Date:7/31/2015)... SHENZHEN, China , 31 de julho de 2015 ... Genômica (ICG-10, www.icg-10.org ) será realizada pela BGI de ... China . A conferência está ... inauguração em 2006, a ICG se tornou uma das ... e um dos encontros científicos mais dinâmicos, entusiastas e ...
(Date:7/31/2015)... --NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... mobile commerce market and creator of the Wocket® smart ... for ELECTRONIC CRYPTO-CURRENCY MANAGEMENT METHOD AND SYSTEM ... crypto-currencies such as Bitcoin into the consumer market of ... manage all payments.  The technology manages ...
(Date:7/27/2015)... 2015   Zynx Health ™, the market ... solutions, today announced that its ZynxCarebook ™ ... Android smartphones and tablets. With this expansion, care ... use ZynxCarebook to securely exchange messages and share ... transitions to other care settings, and improve clinical ...
Breaking Biology News(10 mins):A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 2A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 3NXT-ID Patents Electronic Crypto-Currency Management Technology 2NXT-ID Patents Electronic Crypto-Currency Management Technology 3NXT-ID Patents Electronic Crypto-Currency Management Technology 4Zynx Health Adds Android Device Support to ZynxCarebook Solution 2Zynx Health Adds Android Device Support to ZynxCarebook Solution 3
... Jan. 6, 2011 Acceleron Pharma, Inc., a biopharmaceutical ... cells and tissues including muscle, bone, fat, red blood ... awarded a $1.5 million grant from the Muscular Dystrophy ... Muscular Dystrophy (DMD), a disabling neuromuscular disease in which ...
... that nations should abandon the concept of carbon emissions ... might lead to genuine reductions in the amount of ... provide a mechanism for reducing climate change. Details of ... Interdisciplinary Environmental Review . Carbon emissions trading ...
... The number of women who die from complications of ... last two decades thanks to improved monitoring and better ... report,s lead researcher, Joy Hawkins, MD, professor of anesthesiology ... Colorado School of Medicine, said the risks have been ...
Cached Biology News:Acceleron awarded $1.5 million grant from Muscular Dystrophy Association to support ACE-031 2Carbon swap bank to beat climate change 2Carbon swap bank to beat climate change 3Deaths from anesthesia during childbirth plummet 2
(Date:7/31/2015)... 2015 In today,s fast changing healthcare ... drive positive health outcomes, improve profitability and enhance ... care in their communities. At ThoughtSpot 2015, ... AmerisourceBergen announced a new set of innovative capabilities ... and help independent pharmacies endure the industry,s most ...
(Date:7/30/2015)... ... July 31, 2015 , ... Ralco is honored to announce that it ... Fair to be held August 5-9 in Marshall. The Ralco Enrichment Center is an ... and how agriculture impacts their daily lives. This unique exhibit also features a birthing ...
(Date:7/30/2015)... ... ... The 2015 Market Research Report on the Global Propanol Industry ... market with a focus on the Chinese situation. Major companies included in the propanol ... Sanofi, Royal Dutch Shell, LG Chem and Zhejiang Xinhua Chemical. , The report provides ...
(Date:7/30/2015)...   Senomyx , Inc. (NASDAQ: SNMX ), ... discover, develop, and commercialize novel flavor ingredients for the ... results for the second quarter 2015. ... on track to achieve our commercial and financial goals," ... the Company. "Since our last quarterly earnings report, our ...
Breaking Biology Technology:AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 2AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 3Ralco Announces Primary Sponsorship of Ralco Enrichment Center at Lyon County Fair 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 2Global Propanol Market Technical Data and Manufacturing Analysis 2020 3SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 2SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 3SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 4SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 5SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 6SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 7SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 8SENOMYX ANNOUNCES SECOND QUARTER 2015 FINANCIAL RESULTS 9
... /Xinhua-PRNewswire-FirstCall/ -- 3SBio Inc.,(Nasdaq: SSRX ), a ... and marketing biopharmaceutical,products, today announced its unaudited financial ... Second Quarter 2008 Financial Highlights: ... second quarter 2007 to ...
... To protect potential patients from,being unwitting victims in ... Stem Cell Institute LLC (RSCI),( http://www.RepairStemCells.org ) and ... of the industry,s first standards of,excellence for Repair ... RSC, also known as Adult Stem Cells. Among ...
... on Monday, August 18, 2008, ... Beginning at 1:00 PM Eastern Time, LIVINGSTON, N.J., Aug. ... in,advanced injection technologies, today announced that it plans to report,its results ... the morning,of Thursday, August 14, 2008., Milestone Scientific will also ...
Cached Biology Technology:3SBio Inc. Announces Second Quarter 2008 Results 23SBio Inc. Announces Second Quarter 2008 Results 33SBio Inc. Announces Second Quarter 2008 Results 43SBio Inc. Announces Second Quarter 2008 Results 53SBio Inc. Announces Second Quarter 2008 Results 63SBio Inc. Announces Second Quarter 2008 Results 73SBio Inc. Announces Second Quarter 2008 Results 83SBio Inc. Announces Second Quarter 2008 Results 93SBio Inc. Announces Second Quarter 2008 Results 103SBio Inc. Announces Second Quarter 2008 Results 113SBio Inc. Announces Second Quarter 2008 Results 123SBio Inc. Announces Second Quarter 2008 Results 133SBio Inc. Announces Second Quarter 2008 Results 143SBio Inc. Announces Second Quarter 2008 Results 15Repair Stem Cell Institute Announces Industry's First Standards of Excellence for Global Stem Cell Treatment Centers to Protect Patients from Less-than-Competent Therapeutics 2Milestone to Report Results for 2008 Second Quarter on Thursday, August 14, 2008 2
... Measurement of light production by luciferase-cDNA ... a valuable technique in the development of ... is used as an indicator for the ... the luciferase enzyme is due to advantages ...
... detection of apoptosis and mitochondrial membrane potential. ... early indication of the initiation of cellular ... a collapse in the electrochemical gradient across ... change in the membrane potential (YD). Loss ...
... kit measures mitochondria intactness and detects ... potential. Features and Benefits: ... staining isolated mitochondria and for assaying ... the reagents required for the detection ...
... is expressed in g per ml and is ... pH 6.8, of a 1 mg per ml ... concentration to agglutinate a 2% suspension of human ... at 25 C. Preparation Note: Affinity ...
Biology Products: