Navigation Links
Looking through the eyes of a mouse, scientists monitor circulating cells in its bloodstream
Date:12/3/2007

WASHINGTON, Dec. 3 A team of researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have developed an optical device that allows them to peer through the eyes of a mouse and monitor the cells passing through its bloodstream.

In the Dec. 1 issue of the journal Optics Letters, published by the Optical Society of America, the team describes how they used the device, called a retinal flow cytometer, to non-invasively sample the blood passing through the vessels in the retinal tissue in the back of the eye. There they were able to detect circulating fluorescently labeled cells as they wound their way through the mouse.

"We could detect and count circulating cells continuously without drawing blood samples," says MGH/HMS investigator Charles Lin.

The ability to count circulating cells is important in diseases like multiple myeloma because the number of cancer cells in the bloodstream at the onset of the disease may represent only a tiny fraction of circulating cells in the bloodstream.

Though few in number, these rare cells nevertheless can be relentless. Multiple myeloma starts when cancerous immune system cells residing in the bone marrow quickly multiply out of control. Rather than forming a solid tumor, though, they spread throughout the body and crowd out other cells in the bloodstream. Multiple myeloma cells can invade bones throughout the body, eroding and weakening them and leading to fractures and sometimes paralysis because of compression of the spinal cord. Eroding the bones can also drastically increase the calcium levels in the blood, sometimes causing kidney failure. Moreover, multiple myeloma cells can crowd out the oxygen-ferrying red blood cells in the bloodstream and cause anemia.

Multiple myeloma is treatable, but the disease has a high rate of recurrence. Scientists like Lin and his collaborator Irene Ghobrial of the Dana-Farber
'/>"/>

Contact: Colleen Morrison
cmorri@osa.org
202-416-1437
Optical Society of America
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. M2SYS Partners With Gnosis Medical Services to Provide Accurate Patient Identification in Developing Countries Through Innovative Biometrics Solution
2. Rhythmic breathing adapts to external beat through brain calculus
3. New technique can be breakthrough for early cancer diagnosis
4. Breakthrough research identifies how cells from pigs may cure diabetes
5. Male contraception breakthroughs to be presented, Seattle Sept. 27-28
6. West Nile virus spread through nerve cells linked to serious complication
7. Major genetic breakthrough for ankylosing spondylitis brings treatment hope
8. ACT Ensures Integrity of Testing Process Through Deployment of BIO-keys(R) Biometric ID Technology
9. Oosight microscope enables embryonic stem cell breakthrough
10. UK scientists working to help cut ID theft
11. Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/16/2014)... Northridge, Calif. (October 16, 2014) – Post-menopausal women ... effect on hormone levels or genital bleeding, after ... of an investigational fermented soy germ-based nutritional supplement ... according to a new peer-reviewed pilot study reported ... Society (NAMS) annual scientific meeting. , "These ...
(Date:10/15/2014)... The book ,Models of Life, is a non-traditional biophysics ... itself. The book is a journey of discovery into ... of life and biological regulation. It is about how ... strategic communication between the billions of cells in an ... the relationships between principles, which can be found on ...
(Date:10/15/2014)... Conn. , Oct. 15, 2014 NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile commerce market releases ... MarketSite in Times Square on Monday October 13 th . ... CTO David Tunnel and angel investor Mr. Chad ... Pereira , CEO of NXT-ID thanked his investors and employees "for ...
Breaking Biology News(10 mins):S-equol supplements associated with improved measures of reproductive health in postmenopausal women 2New book about life as seen from physics 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 2Photo Release: NXT-ID Inc. Rings Opening Bell of the NASDAQ Stock Market October 13th 3
... of Michigan,s first human embryonic stem cell line will be ... the cells available for federally-funded research. It is the first ... Michigan to be placed on the registry. The line, ... October 2010 from a cluster of about 30 cells removed ...
... in Salt Lake City is part of a select ... clinical guidelines used by physicians worldwide for the diagnosis ... common cardiovascular diseases in the United States. Scott ... Intermountain Medical Center, says the new guidelines are critically-needed ...
... Economic Forum,s Global Agenda Council on Emerging Technologies has ... change the world in the years ahead. The list ... state of the world in the near future and ... science, businesses, and public policy. The technologies are expected ...
Cached Biology News:U-M human embryonic stem cell line placed on national registry 2U-M human embryonic stem cell line placed on national registry 3New guidelines developed for improved DVT diagnosis 2Important Emerging Technologies for the 21st Century 2Important Emerging Technologies for the 21st Century 3
(Date:10/19/2014)... The report "Unmanned Ground Vehicle Market ... Payload, Type & by Geography - Forecasts & ... ground vehicle market into various sub segments with ... The report also identifies the factors driving this ... with the adoption trends. , The unmanned ground ...
(Date:10/18/2014)... October 18, 2014 The Asia-Pacific ... and segments the bio-based advanced phase change material ... revenue. , Browse through the TOC of the ... to get an idea of the in-depth analysis ... segmentation in the Asia-Pacific bio-based advanced phase change ...
(Date:10/18/2014)... October 18, 2014 The Asia-Pacific hardware ... market in Asia-Pacific with analysis and forecast of revenue. ... is expected to reach $51,362.6 million by 2018, at ... Browse through the TOC of the Asia-Pacific hardware encryption ... analysis provided. This also provides a glimpse of the ...
(Date:10/18/2014)... October 18, 2014 The Biomass ... in the five years to 2014. The industry's expansion ... energy tax credits that encouraged the use of biomass ... portfolio standards (RPSs), which require local utilities to generate ... total energy portfolio. Increased campaigning for green technology also ...
Breaking Biology Technology:Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 2Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 3Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 4Unmanned Ground Vehicle (UGV) Market Estimated to Reach $8.26 Billion by 2020 - New Research Report by MarketsandMarkets 5The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 3The Asia-Pacific Bio-based Advanced Phase Change Materials Market is estimated to grow to $39.8 million by 2018 - New Report by MicroMarket Monitor 4The Asia-Pacific hardware encryption display market is expected to reach $51,362.6 million by 2018 - New Report by MicroMarket Monitor 2The Asia-Pacific hardware encryption display market is expected to reach $51,362.6 million by 2018 - New Report by MicroMarket Monitor 3Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 2Biomass Power in the US Industry Market Research Report from IBISWorld Has Been Updated 3
... 26 Oxygen Biotherapeutics, Inc. (OTC Bulletin Board: OXBO) today ... the addition of two new members. Appointed to the company,s ... Chatfield. With their addition, the company board now has eight ... of the U. S. Selective Service System from November of ...
... Pa., Oct. 26 Cadient Group , ... today announced that it has been recognized as one of ... the Greater Philadelphia region for the second consecutive year. ... during the five year period from 2004-2008. Cadient Group ...
... , ... blue dye test alternative using innovative laser technology has been installed at ... processes. Bayer China has acquired Sepha ’s ‘BlisterScan’ machines for non-destructive leak testing ... ...
Cached Biology Technology:Oxygen Biotherapeutics, Inc. Expands Board of Directors 2Cadient Group Ranks as Deloitte Fast 50 Company for Greater Philadelphia Region for Second Consecutive Year 2Blue Dye Test Alternative Installed at Bayer China for Packaging Quality Assurance Process 2Blue Dye Test Alternative Installed at Bayer China for Packaging Quality Assurance Process 3
... • Dog serum is collected from fasted mixed ... age Available Anticoagulants: N-02: ... K2EDTA N-08: Potassium Oxalate ... N-05: ACD N-07: CPD ...
Ready-to-use; 40mg/ml X-Gal and 32mg/ml IPTG...
Whole blood is collected from canines (any breed, either sex), refrigerated within 6 hours, processed within 24 hours and frozen at -20C....
Designed for flow cytometric applications intended to identify...
Biology Products: