Navigation Links
Looking at neurons from all sides
Date:4/27/2008

HOUSTON (April 28, 2008) A new technique that marries a fast-moving laser beam with a special microscope that look at tissues in different optical planes will enable scientists to get a three-dimensional view of neurons or nerve cells as they interact, said Baylor College of Medicine scientists in a report that appears today in the journal Nature Neuroscience.

Most microscopes can only study cell function in two dimensions, said Dr. Gaddum Duemani Reddy, an M.D./Ph.D. student at BCM at Houston and Rice University and also first author of the study. To look at different planes, you have move your preparation (of cells) or the objective lens. That takes time, and we are looking at processes that happen in milliseconds.

To solve that problem, he said, they developed a trick to quickly move a laser beam in three dimensions and then adapted that laser beam to the multi-photon microscope they were using. That allowed them to see the neurons function in three dimensions, giving them a much better view of its activity.

A multiphoton microscope looks much like a conventional, upright microscope but it has an adaption that allows it to look at tissues in sections. A conventional multiphoton microscope does that very slowly, he said.

With ours, you can do it very quickly. We are starting to see how a single neuron behaves in our laboratory, he said. The next step, he said, will be to use to it to look a clusters or colonies of neurons. This will enable them to actually see the neuronal interactions.

At present, the technology is applied in my lab to study information processing of single neurons in brain slice preparations by 3D multi-site optical recording, said Dr. Peter Saggau, professor of neuroscience at BCM and the papers senior author.

He is collaborating with two other labs on using the technology in other ways. In one, he said, researchers plan to use the technology to monitor nerve activity in the bra
'/>"/>

Contact: Graciela Gutierrez
ggutierr@bcm.edu
713-798-4712
Baylor College of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. Looking through the eyes of a mouse, scientists monitor circulating cells in its bloodstream
2. Inflammation triggers cell fusions that could protect neurons, Stanford research shows
3. Neurons hard wired to tell left from right
4. Weill Cornell team discovers how brains own tPA helps regulate blood flow to neurons
5. Overexcited neurons not good for cell health
6. The birth and death of dopamine neurons: A new model for neurodegeneration
7. The accumulation of sugar in neurons may explain the origin of several neurodegenerative diseases
8. Mice use specialized neurons to detect carbon dioxide in the air
9. Sidestepping cancers chaperone
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... - Today, FindBiometrics, the leading source of biometrics industry news, interviews ... design. "When we launched FindBiometrics 12 years ago ... , founder and CEO of FindBiometrics. "Now it,s maturing very ... key players on a very broad scale.  We are known ...
(Date:1/22/2015)... Inc. (NASDAQ: NXTD and NXTDW) a biometric authentication company ... of the Wocket™ smart wallet at CES 2015 in Las ... one of the "11 Hot Products at CES" in a review published ... Far" by Newseveryday.com and "The top 10 gadgets from CES 2015" by ...
(Date:1/22/2015)... 2015   EyeLock, Inc. , a market leader of iris-based ... Gerber to the new role of Senior Vice President ... development of mobile platforms and wearable solutions for EyeLock,s technologies. ... in the semiconductor industry to his role at EyeLock, with ...
Breaking Biology News(10 mins):Identity Industry Leading Publication Debuts New Look As Biometrics Hit Mainstream 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2
... 18, 2012) Seeking to solve some of today,s ... at national research laboratories in the United States and ... Source and the Advanced Photon Source (APS) at the ... in January 2012 to a Partner User Proposal that ...
... absorb the greenhouse gas carbon dioxide to an ever-decreasing extent. ... atmosphere and an increase in the rate of warming in ... at the University of Gothenburg, Sweden. Most scientists consider ... amounts of greenhouse gases released by humans from, for example, ...
... More than 1,500 scientists will descend on Virginia Tech beginning ... information but also an economic boost to the Blacksburg area ... MACRO 2012, is one of the largest conferences ever held ... meeting. It,s all about large molecules macromolecules that ...
Cached Biology News:Advanced Photon Source and Canadian Light Source strengthen ties 2Increasing levels of carbon dioxide in Arctic coastal seas 2Scientific meeting at Virginia Tech will make more than $2 million economic impact 2Scientific meeting at Virginia Tech will make more than $2 million economic impact 3
(Date:1/23/2015)... Portal Solutions , a technology consulting firm that designs ... and SharePoint platforms , today announces its inclusion in Washington ... the region’s fastest-growing mid-sized companies based on a combined three-year ... recognized a second year in a row by SmartCEO is ...
(Date:1/22/2015)... BOSTON , Jan. 22, 2015  Transwestern | RBJ today ... feet of office space for Shire a leading biopharmaceutical company, ... . Transwestern | RBJ,s Robert Richards , president, and ... the lease for the entire five-floor building at 95 Hayden ...
(Date:1/22/2015)... (PRWEB) January 21, 2015 Cambridge Semantics, the ... technology, today announced that 2014 was a record-breaking year across ... capabilities of the Anzo Smart Data Platform and our Smart ... utilize insights from diverse data which led to record growth ...
(Date:1/22/2015)... Crystal Diagnostics (CDx) Xpress System, a rapid ... AOAC-PTM Certifications for the six non-O157 Shiga toxin-producing E. coli ... to as STEC or the “Big-6”) as well as Escherichia ... per 325 g of raw ground beef and raw beef ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Cambridge Semantics Announces Record Results for 2014 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2
... DCGN ) announced that on February 2, 2009, ... (the "Panel") stating that the Panel,will transfer the listing ... the Nasdaq Capital Market, effective at the open of ... Capital Market, which is,one of the three market tier ...
... Health,Inc. (Nasdaq: GHDX ) today reported financial results ... 31, 2008. , Total revenue for ... $19.3 million in the fourth quarter of 2007. Product ... in the fourth,quarter of 2008, an increase of 60 percent, ...
... Abt Associates announced that Ricky Takai, Ph.D., has ... brief orientation to the firm, Dr. Takai will become ... 2009. Dr. Takai brings his more than 20 ... evaluation studies in the field of education to the ...
Cached Biology Technology:deCODE Announces Transfer of the Listing of its Common Stock from Nasdaq Global Market to Nasdaq Capital Market 2deCODE Announces Transfer of the Listing of its Common Stock from Nasdaq Global Market to Nasdaq Capital Market 3Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 2Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 3Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 4Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 5Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 6Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 7Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 8Genomic Health Announces Fourth Quarter and Year-End 2008 Financial Results and Business Progress, Provides 2009 Financial Guidance 9Dr. Ricky Takai, Expert in Designing and Managing Federal Evaluation Studies in Education, Joins Abt Associates 2
... medium Reagent B - Permeabilisation medium ... in suspension with Reagent A and then ... procedure gives antibodies access to intracellular structures ... the cells intact. Specific formulations reduce background ...
... is formulated for covering tissue sections and cell preparations immunohistochemically ... products. , ... Application: Vision ... AEC that require an aqueous mounting medium, or those that ...
... Target Retrieval Solution, High pH This ... target retrievel prior to immunohistochemical staining procedures. ... tissue sections mounted on glass slides. For ... 9.9, is especially effective. It should be ...
Collected from calves that are 10 days old or less. Sterile, cell culture tested, US Origin...
Biology Products: