Navigation Links
Looking at neurons from all sides
Date:4/27/2008

HOUSTON (April 28, 2008) A new technique that marries a fast-moving laser beam with a special microscope that look at tissues in different optical planes will enable scientists to get a three-dimensional view of neurons or nerve cells as they interact, said Baylor College of Medicine scientists in a report that appears today in the journal Nature Neuroscience.

Most microscopes can only study cell function in two dimensions, said Dr. Gaddum Duemani Reddy, an M.D./Ph.D. student at BCM at Houston and Rice University and also first author of the study. To look at different planes, you have move your preparation (of cells) or the objective lens. That takes time, and we are looking at processes that happen in milliseconds.

To solve that problem, he said, they developed a trick to quickly move a laser beam in three dimensions and then adapted that laser beam to the multi-photon microscope they were using. That allowed them to see the neurons function in three dimensions, giving them a much better view of its activity.

A multiphoton microscope looks much like a conventional, upright microscope but it has an adaption that allows it to look at tissues in sections. A conventional multiphoton microscope does that very slowly, he said.

With ours, you can do it very quickly. We are starting to see how a single neuron behaves in our laboratory, he said. The next step, he said, will be to use to it to look a clusters or colonies of neurons. This will enable them to actually see the neuronal interactions.

At present, the technology is applied in my lab to study information processing of single neurons in brain slice preparations by 3D multi-site optical recording, said Dr. Peter Saggau, professor of neuroscience at BCM and the papers senior author.

He is collaborating with two other labs on using the technology in other ways. In one, he said, researchers plan to use the technology to monitor nerve activity in the bra
'/>"/>

Contact: Graciela Gutierrez
ggutierr@bcm.edu
713-798-4712
Baylor College of Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. Looking through the eyes of a mouse, scientists monitor circulating cells in its bloodstream
2. Inflammation triggers cell fusions that could protect neurons, Stanford research shows
3. Neurons hard wired to tell left from right
4. Weill Cornell team discovers how brains own tPA helps regulate blood flow to neurons
5. Overexcited neurons not good for cell health
6. The birth and death of dopamine neurons: A new model for neurodegeneration
7. The accumulation of sugar in neurons may explain the origin of several neurodegenerative diseases
8. Mice use specialized neurons to detect carbon dioxide in the air
9. Sidestepping cancers chaperone
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... DUBLIN , June 25, 2015 ... the addition of the "Next Generation Biometrics Market ... to 2020" report to their offering. ... $24.4 Billion by 2020, at a CAGR of 17.9% ... is the leading application for the market. Safran ...
(Date:6/30/2015)... June 30, 2015 Genisphere announced ... CEO to help further develop Genisphere,s therapeutics capabilities and ... experience, having spent much of the last 25 years ... Baxter Bioscience, and Johnson & Johnson. Tom started his ... and Biotech Corporate Finance. He graduated from Dartmouth College ...
(Date:6/25/2015)... -- According to a new market ... Technology, Material (Optical Prism, Piezoelectric, Capacitive & Adhesives), ... & Geography - Global Forecast to 2014 - ... expected to reach $14,500.07 Million by 2020, at ... 76 market Tables and 109 Figures spread through ...
Breaking Biology News(10 mins):Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 3Genisphere Appoints New CEO, Thomas Bliss 2Genisphere Appoints New CEO, Thomas Bliss 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 4
... may be uncomfortable at first, but doing exercises to strengthen ... osteoarthritis is critical to your recovery. In fact, it can ... of a healthy adult your age. That,s the finding ... issue of Arthritis Care & Research . ...
... You don,t have to get wet, or seasick, to ... worldwide. Just tune in through your computer. This morning ... available to computers everywhere was launched at the California ... Barbara are involved in the project. "The Marine Science ...
... Women who have higher levels of a hormone produced ... to develop postpartum depression, a study authored by a ... identify and treat women at risk for postpartum depression ... psychology and social behavior assistant professor, and colleagues found ...
Cached Biology News:Exercise after knee replacement critical 2New version of Google Earth features California's marine protected areas 2
(Date:7/27/2015)... 2015 Research presented at the 2015 AACC ... the studies that led to a fingerprick Ebola test ... disease to receive approval from the World Health Organization ... grip on West Africa by ... workers to isolate and treat these patients much faster ...
(Date:7/27/2015)... , July 27, 2015 Junto Health, a ... share information and develop new technology solutions, today announced ... Group (SPG), a leader in health care policy consulting. ... engage in a collaborative innovation process while, at the ... trends in public policy, health care finance and the ...
(Date:7/25/2015)... ... , ... Technology leader Anton Paar offers the Abbemat ... temperature of the measuring prism. This is required to achieve the most precise ... key requirements. It is likely that no refractometer manufacturers on the market can ...
(Date:7/24/2015)... N.J. , July 24, 2015  Champions Oncology ... advanced technology solutions and services to personalize the development ... report its financial and operational results for the fourth ... on Tuesday, July 28, 2015, before market open. ... discuss the results that day at 9:00 a.m. EDT ...
Breaking Biology Technology:Rapid Ebola Test Could Play Key Role in Efforts to End Lingering Outbreak 2Rapid Ebola Test Could Play Key Role in Efforts to End Lingering Outbreak 3Junto Health Announces a Unique Partnership with Sachs Policy Group 2Junto Health Announces a Unique Partnership with Sachs Policy Group 3Junto Health Announces a Unique Partnership with Sachs Policy Group 4It’s T-Time for Refractometers: On-site Temperature Check Now Available 2Champions Oncology to Announce Fourth Quarter Financial Results on Tuesday, July 28 2
... Japan,s first second-generation drug-eluting stentNATICK, Mass., Jan. 28 ... ) announced today that it has received approval ... Welfare (MHLW) to market its TAXUS(R) Liberte(R) Paclitaxel-Eluting ... launch the product as soon as reimbursement approval ...
... Clinical Services, will lead a panel of top pharmaceutical financial experts ... CBI Forecasting & Budgeting conference. The panel will demonstrate practical ... management of clinical trial cash flow and accruals. , ... ...
... Bion Environmental Technologies, Inc. (OTC Bulletin Board: ... 2009, the Pennsylvania Infrastructure Investment Authority (PENNVEST) approved ... LLC (a wholly-owned subsidiary of Bion Environmental Technologies, ... used to construct Bion,s previously announced Kreider Farms ...
Cached Biology Technology:Boston Scientific Announces Japanese Approval for TAXUS(R) Liberte(R) Drug-Eluting Stent System 2Boston Scientific Announces Japanese Approval for TAXUS(R) Liberte(R) Drug-Eluting Stent System 3ClearTrial Selected to Lead Industry Panel on Managing Clinical Trial Cash Flow and Accruals at CBI Conference 2ClearTrial Selected to Lead Industry Panel on Managing Clinical Trial Cash Flow and Accruals at CBI Conference 3Bion Announces PENNVEST Board Approves $7.8 Million Financing for Kreider Farms Dairy Project 2Bion Announces PENNVEST Board Approves $7.8 Million Financing for Kreider Farms Dairy Project 3Bion Announces PENNVEST Board Approves $7.8 Million Financing for Kreider Farms Dairy Project 4
... Chemicon Select Tissue Arrays are intended ... individual tissues were fixed in neutral buffered ... identification and diagnosis was performed by certified ... their paraffin blocks and relocated into a ...
... 50 X-Ray System from KUBTEC is a dual ... and three dimensional representation of the specimen under ... of specimen X-ray images, the micro focus source ... of detail in standard 2D images. The 50 ...
... BTX, the leader in electroporation products and ... innovative product line for experiment optimization and ... is a breakthrough in Molecular Delivery. The ... procedures that typically limited the number of ...
... Progesterone Receptor (PR) Competitor Assay Kits ... novel progesterone receptor binding compounds using ... utilizes a fusion of glutathione transferase ... human progesterone receptor [PR-LBD(GST)] and a ...
Biology Products: